NO20004798L - Barbitursyrederivat og forebyggende og terapeutisk middel for ben og brusk inneholdende det samme - Google Patents
Barbitursyrederivat og forebyggende og terapeutisk middel for ben og brusk inneholdende det sammeInfo
- Publication number
- NO20004798L NO20004798L NO20004798A NO20004798A NO20004798L NO 20004798 L NO20004798 L NO 20004798L NO 20004798 A NO20004798 A NO 20004798A NO 20004798 A NO20004798 A NO 20004798A NO 20004798 L NO20004798 L NO 20004798L
- Authority
- NO
- Norway
- Prior art keywords
- substituted
- acid derivative
- barbituric acid
- bone
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Barbitursyrederivat ifølge formel (I), der R og R1 uavhengig betegner et hydrogenatom, substituert eller usubstituert alkylgruppe eller GI - Ci5 - alkenylgruppe, en substituert eller usubstituert arylmetylgruppe, og substituert eller usubstituert arylgruppe, og R2 betegner en substituert eller usubstituert alkylgruppe eller Ci - C,5 alkenylgruppe, en substituert eller usubstituert arylmetylgruppe, og substituert eller usubstituert arylgruppe. Barbitursyrederivatet ifølge oppfinnelsen har en sterk inhiberende aktivitet på benresorpsjon og er et nyttig j.UiCuy ggcriuc Og terapeutisk iiiiddel for behandling av sykdommer som påvirker ben og brusk.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10100355A JPH11279157A (ja) | 1998-03-27 | 1998-03-27 | バルビツール酸誘導体およびそれらからなる骨・軟骨疾患予防・治療薬 |
PCT/IB1999/000961 WO1999050252A2 (en) | 1998-03-27 | 1999-03-23 | Barbituric acid derivative and preventive and therapeutic agent for bone and cartilage containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20004798D0 NO20004798D0 (no) | 2000-09-26 |
NO20004798L true NO20004798L (no) | 2000-11-20 |
Family
ID=14271794
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20004798A NO20004798L (no) | 1998-03-27 | 2000-09-26 | Barbitursyrederivat og forebyggende og terapeutisk middel for ben og brusk inneholdende det samme |
Country Status (20)
Country | Link |
---|---|
US (1) | US6498164B1 (no) |
EP (1) | EP1064269A1 (no) |
JP (1) | JPH11279157A (no) |
KR (1) | KR20010042182A (no) |
CN (1) | CN1295565A (no) |
AU (1) | AU759249B2 (no) |
BR (1) | BR9909139A (no) |
CA (1) | CA2324584A1 (no) |
CZ (1) | CZ20003460A3 (no) |
EA (1) | EA200000992A1 (no) |
HU (1) | HUP0101505A3 (no) |
IL (1) | IL138433A0 (no) |
NO (1) | NO20004798L (no) |
NZ (1) | NZ506616A (no) |
PL (1) | PL343433A1 (no) |
SK (1) | SK14032000A3 (no) |
TR (1) | TR200002785T2 (no) |
WO (1) | WO1999050252A2 (no) |
YU (1) | YU57800A (no) |
ZA (1) | ZA200004473B (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050261288A1 (en) * | 2004-02-26 | 2005-11-24 | Prakash Jagtap | Tetracyclic lactam derivatives and uses thereof |
CN102070623B (zh) * | 2010-12-20 | 2012-07-25 | 新乡医学院 | 一种巴比妥酸衍生物及其制备方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2921072A (en) * | 1956-10-18 | 1960-01-12 | Jr Edgar A Ferguson | Nicotinic acid substituents of barbituric acid |
GB1339748A (en) * | 1970-07-02 | 1973-12-05 | Ici Ltd | Pyrimidine derivatives |
JPS5829281B2 (ja) * | 1974-06-04 | 1983-06-22 | 日本曹達株式会社 | バルビツ−ル酸系除草剤 |
US4695673A (en) * | 1985-11-20 | 1987-09-22 | Stauffer Chemical Company | Process for the production of acylated 1,3-dicarbonyl compounds |
US4797147A (en) * | 1986-06-09 | 1989-01-10 | Stauffer Chemical Company | Herbicidal method and composition utilizing certain 5-(2-substituted benzoyl)-barbituric acids |
US4938796A (en) * | 1987-07-06 | 1990-07-03 | Ici Americas Inc. | Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and antidotes therefor |
JP2588780B2 (ja) * | 1989-09-26 | 1997-03-12 | 富士写真フイルム株式会社 | 電子写真感光体 |
JP2588779B2 (ja) * | 1989-09-18 | 1997-03-12 | 富士写真フイルム株式会社 | 電子写真式製版用印刷原版 |
DE4029565B9 (de) * | 1989-09-18 | 2005-03-10 | Fuji Photo Film Co Ltd | Elektrophotographisches Aufzeichnungsmaterial und elektrophotographischer Druckplattenvorläufer, die ein Phthalocyaninpigment und ein Thiobarbitursäurederivat enthalten |
JPH03179361A (ja) * | 1989-12-07 | 1991-08-05 | Fuji Photo Film Co Ltd | 光導電性組成物およびそれを用いた電子写真感光材料 |
US5141943A (en) * | 1990-04-12 | 1992-08-25 | Brown University Research Foundation | 5-benzyl barbiturate derivatives |
NL9001075A (no) * | 1990-05-04 | 1991-12-02 | Duphar Int Res | |
DE59208375D1 (de) * | 1991-06-05 | 1997-05-28 | Ciba Geigy Ag | Benzo-1,2,3-thiadiazol-Derivate |
EP0809634A4 (en) * | 1995-02-13 | 1998-05-20 | Kirpal S Gulliya | NEW USES FOR BARBITURIC ACID ANALOGS |
JPH10316608A (ja) * | 1997-05-14 | 1998-12-02 | Hoechst Yakuhin Kogyo Kk | ポリヒドロキシフェノール誘導体およびそれらからなる骨・軟骨疾患予防・治療剤 |
-
1998
- 1998-03-27 JP JP10100355A patent/JPH11279157A/ja active Pending
-
1999
- 1999-03-23 WO PCT/IB1999/000961 patent/WO1999050252A2/en not_active Application Discontinuation
- 1999-03-23 EA EA200000992A patent/EA200000992A1/ru unknown
- 1999-03-23 CA CA002324584A patent/CA2324584A1/en not_active Abandoned
- 1999-03-23 BR BR9909139-9A patent/BR9909139A/pt not_active IP Right Cessation
- 1999-03-23 AU AU37260/99A patent/AU759249B2/en not_active Ceased
- 1999-03-23 NZ NZ506616A patent/NZ506616A/xx unknown
- 1999-03-23 YU YU57800A patent/YU57800A/sh unknown
- 1999-03-23 SK SK1403-2000A patent/SK14032000A3/sk unknown
- 1999-03-23 IL IL13843399A patent/IL138433A0/xx unknown
- 1999-03-23 EP EP99919495A patent/EP1064269A1/en not_active Withdrawn
- 1999-03-23 CN CN99804571A patent/CN1295565A/zh active Pending
- 1999-03-23 HU HU0101505A patent/HUP0101505A3/hu unknown
- 1999-03-23 KR KR1020007010669A patent/KR20010042182A/ko not_active Application Discontinuation
- 1999-03-23 TR TR2000/02785T patent/TR200002785T2/xx unknown
- 1999-03-23 PL PL99343433A patent/PL343433A1/xx unknown
- 1999-03-23 US US09/647,280 patent/US6498164B1/en not_active Expired - Fee Related
- 1999-03-23 CZ CZ20003460A patent/CZ20003460A3/cs unknown
-
2000
- 2000-08-29 ZA ZA200004473A patent/ZA200004473B/xx unknown
- 2000-09-26 NO NO20004798A patent/NO20004798L/no unknown
Also Published As
Publication number | Publication date |
---|---|
SK14032000A3 (sk) | 2001-03-12 |
PL343433A1 (en) | 2001-08-13 |
HUP0101505A2 (hu) | 2002-03-28 |
CZ20003460A3 (cs) | 2001-08-15 |
CA2324584A1 (en) | 1999-10-07 |
TR200002785T2 (tr) | 2001-02-21 |
WO1999050252A3 (en) | 2000-01-13 |
BR9909139A (pt) | 2000-12-05 |
CN1295565A (zh) | 2001-05-16 |
ZA200004473B (en) | 2001-05-30 |
YU57800A (sh) | 2002-10-18 |
AU3726099A (en) | 1999-10-18 |
EA200000992A1 (ru) | 2001-06-25 |
EP1064269A1 (en) | 2001-01-03 |
NZ506616A (en) | 2003-04-29 |
AU759249B2 (en) | 2003-04-10 |
HUP0101505A3 (en) | 2002-06-28 |
NO20004798D0 (no) | 2000-09-26 |
IL138433A0 (en) | 2001-10-31 |
WO1999050252A2 (en) | 1999-10-07 |
JPH11279157A (ja) | 1999-10-12 |
KR20010042182A (ko) | 2001-05-25 |
US6498164B1 (en) | 2002-12-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20020968L (no) | Glukopyranosyloksypyrazolderivater, medisinske sammensetninger inneholdende det samme og intermediater forfremstillingen derav | |
NO20051010L (no) | Triazolderivater som transformerende vekst faktor (TGF) inhibitorer | |
DE69521424D1 (de) | Benzofuran derivate und ihre verwendung als inhibitoren der knochenresorption | |
DE60012751D1 (de) | Verwendung von ep4 rezeptorliganden zur behandlung von neuropathischen schmerz | |
IL178350A (en) | Vitamin d derivatives | |
DE69935718D1 (de) | Antidiabetische medikamente | |
DE69524598D1 (de) | Kondensierte imidazolderivate, ihre herstellung und verwendung | |
DE50011034D1 (de) | N-substituierte 4-aminopteridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
ATE316962T1 (de) | Pyrimidin-derivate als selective inhibitoren von cox-2 | |
DE69623497D1 (de) | 1-methylcarbapenem-derivate | |
DE69828197D1 (de) | Amidderivate zur behandlung neurodegenerativer erkrankungen der netzhaut | |
NO20004798L (no) | Barbitursyrederivat og forebyggende og terapeutisk middel for ben og brusk inneholdende det samme | |
ATE254607T1 (de) | Pyrimidinderivate | |
ES2158290T3 (es) | Derivados de tiazolidinona opticamente activos. | |
NO985298L (no) | Polyhydroksyfenolderivater og forebyggende og terapeutiske midler for ben- | |
ATE278701T1 (de) | Malto-oligosaccharide und deren verwendung | |
WO2005025492A3 (en) | Novel compositions, pharmaceutical compositions, and methods for the treatment and prevention of heart disease |