ES2158290T3 - Derivados de tiazolidinona opticamente activos. - Google Patents

Derivados de tiazolidinona opticamente activos.

Info

Publication number
ES2158290T3
ES2158290T3 ES96904292T ES96904292T ES2158290T3 ES 2158290 T3 ES2158290 T3 ES 2158290T3 ES 96904292 T ES96904292 T ES 96904292T ES 96904292 T ES96904292 T ES 96904292T ES 2158290 T3 ES2158290 T3 ES 2158290T3
Authority
ES
Spain
Prior art keywords
sub
optically active
sup
substitutes
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96904292T
Other languages
English (en)
Inventor
Sadao Ishihara
Fujio Saito
Yasuo Ohhata
Shigeki Miyake
Ryosuke Yorikane
Norio Fukuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of ES2158290T3 publication Critical patent/ES2158290T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Soil Working Implements (AREA)
  • Supplying Of Containers To The Packaging Station (AREA)

Abstract

DERIVADOS DE TIAZOLIDINONA CON LA FORMULA GENERAL (I) [EN DONDE R{SUP,1} REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO C{SUB,1} ITUIDO (SIENDO DICHOS SUSTITUYENTES C{SUB,1} O, C{SUB,1} B,1} LQUILO SUSTITUIDO (SIENDO LOS SUSTITUYENTES DE DICHO FENILO C{SUB,1} NO); R{SUP,2} REPRESENTA UN GRUPO ALQUILO C{SUB,1} Y N REPRESENTA 1 O 2]. LOS DERIVADOS OPTICAMENTE ACTIVOS DE LAS TIAZOLIDINONAS DE LA PRESENTE INVENCION POSEEN EXCELENTE ACTIVIDAD ANTI ANGINA DE PECHO Y SON UTILES COMO AGENTES PREVENTIVOS O AGENTES TERAPEUTICOS PARA LA ANGINA DE PECHO.
ES96904292T 1995-03-02 1996-03-01 Derivados de tiazolidinona opticamente activos. Expired - Lifetime ES2158290T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4223795 1995-03-02
JP27995195 1995-10-27

Publications (1)

Publication Number Publication Date
ES2158290T3 true ES2158290T3 (es) 2001-09-01

Family

ID=26381885

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96904292T Expired - Lifetime ES2158290T3 (es) 1995-03-02 1996-03-01 Derivados de tiazolidinona opticamente activos.

Country Status (18)

Country Link
EP (1) EP0812835B1 (es)
KR (1) KR100292737B1 (es)
CN (1) CN1066725C (es)
AT (1) ATE201402T1 (es)
AU (1) AU701977B2 (es)
CA (1) CA2214386C (es)
CZ (1) CZ290989B6 (es)
DE (1) DE69612967T2 (es)
DK (1) DK0812835T3 (es)
ES (1) ES2158290T3 (es)
GR (1) GR3036029T3 (es)
HK (2) HK1003890A1 (es)
HU (1) HU223094B1 (es)
NO (1) NO309525B1 (es)
NZ (1) NZ302391A (es)
PT (1) PT812835E (es)
RU (1) RU2141956C1 (es)
WO (1) WO1996026931A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0798298T3 (da) * 1994-12-15 2001-10-22 Sankyo Co Thiazolidinon- eller oxazolidonderivater til behandling af angina pectoris eller sammensætninger indeholdende samme som aktiv bestanddel
WO2002069967A1 (fr) * 2001-03-01 2002-09-12 Sankyo Company, Limited Compositions a absorption percutanee
CN1902184A (zh) 2003-11-18 2007-01-24 田纳西大学研究基金会 噻唑烷酮酰胺、噻唑烷羧酸酰胺、其制备方法及其用途
TWI400220B (zh) 2004-09-13 2013-07-01 Takeda Pharmaceutical 光活性胺衍生物的製法
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
US9029408B2 (en) 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
PT2959900T (pt) 2008-06-16 2017-06-22 Univ Tennessee Res Found Composto para tratamento do cancro
US8822513B2 (en) 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
CN102883607B (zh) 2010-03-01 2015-07-22 Gtx公司 用于治疗癌的化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8717068D0 (en) * 1987-07-20 1987-08-26 Fujisawa Pharmaceutical Co Nitric ester derivative
US5298516A (en) * 1991-03-27 1994-03-29 Sankyo Company, Limited Thiazolidone compounds and method of using the same as a vasodilator

Also Published As

Publication number Publication date
HU223094B1 (hu) 2004-03-29
RU2141956C1 (ru) 1999-11-27
ATE201402T1 (de) 2001-06-15
HK1016579A1 (en) 1999-11-05
EP0812835B1 (en) 2001-05-23
NO974004D0 (no) 1997-09-01
HUP9900320A2 (hu) 1999-05-28
NO309525B1 (no) 2001-02-12
CN1183096A (zh) 1998-05-27
DK0812835T3 (da) 2001-07-09
NZ302391A (en) 1999-04-29
CA2214386C (en) 2001-12-04
AU701977B2 (en) 1999-02-11
EP0812835A4 (en) 1998-04-29
MX9706627A (es) 1997-11-29
HK1003890A1 (en) 1998-11-13
KR100292737B1 (ko) 2001-09-17
AU4843896A (en) 1996-09-18
NO974004L (no) 1997-11-03
CZ290989B6 (cs) 2002-11-13
HUP9900320A3 (en) 1999-11-29
CA2214386A1 (en) 1996-09-06
PT812835E (pt) 2001-08-30
GR3036029T3 (en) 2001-09-28
WO1996026931A1 (fr) 1996-09-06
DE69612967T2 (de) 2002-04-04
DE69612967D1 (en) 2001-06-28
CN1066725C (zh) 2001-06-06
CZ273497A3 (cs) 1998-02-18
EP0812835A1 (en) 1997-12-17
KR19980702707A (ko) 1998-08-05

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