DE69612967T2 - Optisch aktive thiazolidinonderivate - Google Patents

Optisch aktive thiazolidinonderivate

Info

Publication number
DE69612967T2
DE69612967T2 DE69612967T DE69612967T DE69612967T2 DE 69612967 T2 DE69612967 T2 DE 69612967T2 DE 69612967 T DE69612967 T DE 69612967T DE 69612967 T DE69612967 T DE 69612967T DE 69612967 T2 DE69612967 T2 DE 69612967T2
Authority
DE
Germany
Prior art keywords
optically active
alkyl group
phenyl
alkyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69612967T
Other languages
English (en)
Other versions
DE69612967D1 (en
Inventor
Sadao Ishihara
Fujio Saito
Yasuo Ohhata
Shigeki Miyake
Ryosuke Yorikane
Norio Fukuda
Keiichi Tabata
Mitsuko Makino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE69612967D1 publication Critical patent/DE69612967D1/de
Publication of DE69612967T2 publication Critical patent/DE69612967T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Soil Working Implements (AREA)
  • Supplying Of Containers To The Packaging Station (AREA)
DE69612967T 1995-03-02 1996-03-01 Optisch aktive thiazolidinonderivate Expired - Fee Related DE69612967T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP4223795 1995-03-02
JP27995195 1995-10-27
PCT/JP1996/000487 WO1996026931A1 (fr) 1995-03-02 1996-03-01 Derives de thiazolidinone optiquement actifs

Publications (2)

Publication Number Publication Date
DE69612967D1 DE69612967D1 (en) 2001-06-28
DE69612967T2 true DE69612967T2 (de) 2002-04-04

Family

ID=26381885

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69612967T Expired - Fee Related DE69612967T2 (de) 1995-03-02 1996-03-01 Optisch aktive thiazolidinonderivate

Country Status (18)

Country Link
EP (1) EP0812835B1 (de)
KR (1) KR100292737B1 (de)
CN (1) CN1066725C (de)
AT (1) ATE201402T1 (de)
AU (1) AU701977B2 (de)
CA (1) CA2214386C (de)
CZ (1) CZ290989B6 (de)
DE (1) DE69612967T2 (de)
DK (1) DK0812835T3 (de)
ES (1) ES2158290T3 (de)
GR (1) GR3036029T3 (de)
HK (2) HK1003890A1 (de)
HU (1) HU223094B1 (de)
NO (1) NO309525B1 (de)
NZ (1) NZ302391A (de)
PT (1) PT812835E (de)
RU (1) RU2141956C1 (de)
WO (1) WO1996026931A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ292626B6 (cs) * 1994-12-15 2003-11-12 Sankyo Company Limited Thiazolidinonové sloučeniny, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje
WO2002069967A1 (fr) * 2001-03-01 2002-09-12 Sankyo Company, Limited Compositions a absorption percutanee
US7307093B2 (en) 2003-11-18 2007-12-11 The University Of Tennessee Research Foundation Thiazolidinone amides, thiazolidine carboxylic acid amides, methods of making, and uses thereof
TWI400220B (zh) 2004-09-13 2013-07-01 Takeda Pharmaceutical 光活性胺衍生物的製法
US9029408B2 (en) 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
DK3289876T3 (da) 2008-06-16 2022-10-10 Univ Tennessee Res Found Forbindelser til behandling af cancer
US8822513B2 (en) 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
CN104592205A (zh) 2010-03-01 2015-05-06 Gtx公司 用于治疗癌的化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8717068D0 (en) * 1987-07-20 1987-08-26 Fujisawa Pharmaceutical Co Nitric ester derivative
US5298516A (en) * 1991-03-27 1994-03-29 Sankyo Company, Limited Thiazolidone compounds and method of using the same as a vasodilator

Also Published As

Publication number Publication date
CN1066725C (zh) 2001-06-06
AU701977B2 (en) 1999-02-11
CZ273497A3 (cs) 1998-02-18
RU2141956C1 (ru) 1999-11-27
HUP9900320A3 (en) 1999-11-29
EP0812835A4 (de) 1998-04-29
EP0812835B1 (de) 2001-05-23
AU4843896A (en) 1996-09-18
KR100292737B1 (ko) 2001-09-17
MX9706627A (es) 1997-11-29
HU223094B1 (hu) 2004-03-29
DK0812835T3 (da) 2001-07-09
NO974004D0 (no) 1997-09-01
WO1996026931A1 (fr) 1996-09-06
DE69612967D1 (en) 2001-06-28
HK1003890A1 (en) 1998-11-13
CA2214386C (en) 2001-12-04
CZ290989B6 (cs) 2002-11-13
HUP9900320A2 (hu) 1999-05-28
NO974004L (no) 1997-11-03
ES2158290T3 (es) 2001-09-01
ATE201402T1 (de) 2001-06-15
NO309525B1 (no) 2001-02-12
EP0812835A1 (de) 1997-12-17
NZ302391A (en) 1999-04-29
CA2214386A1 (en) 1996-09-06
CN1183096A (zh) 1998-05-27
HK1016579A1 (en) 1999-11-05
PT812835E (pt) 2001-08-30
GR3036029T3 (en) 2001-09-28
KR19980702707A (ko) 1998-08-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee