NO309525B1 - Optisk aktive tiazolidinonderivater og farmasöytisk preparat inneholdende disse - Google Patents
Optisk aktive tiazolidinonderivater og farmasöytisk preparat inneholdende disse Download PDFInfo
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- NO309525B1 NO309525B1 NO974004A NO974004A NO309525B1 NO 309525 B1 NO309525 B1 NO 309525B1 NO 974004 A NO974004 A NO 974004A NO 974004 A NO974004 A NO 974004A NO 309525 B1 NO309525 B1 NO 309525B1
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- optically active
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- 230000008020 evaporation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- FPVGTPBMTFTMRT-NSKUCRDLSA-L fast yellow Chemical compound [Na+].[Na+].C1=C(S([O-])(=O)=O)C(N)=CC=C1\N=N\C1=CC=C(S([O-])(=O)=O)C=C1 FPVGTPBMTFTMRT-NSKUCRDLSA-L 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- KIWBRXCOTCXSSZ-UHFFFAOYSA-N hexyl carbonochloridate Chemical compound CCCCCCOC(Cl)=O KIWBRXCOTCXSSZ-UHFFFAOYSA-N 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 150000003840 hydrochlorides Chemical class 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- NPZTUJOABDZTLV-UHFFFAOYSA-N hydroxybenzotriazole Substances O=C1C=CC=C2NNN=C12 NPZTUJOABDZTLV-UHFFFAOYSA-N 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 229960003511 macrogol Drugs 0.000 description 1
- 229940037627 magnesium lauryl sulfate Drugs 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- HBNDBUATLJAUQM-UHFFFAOYSA-L magnesium;dodecyl sulfate Chemical compound [Mg+2].CCCCCCCCCCCCOS([O-])(=O)=O.CCCCCCCCCCCCOS([O-])(=O)=O HBNDBUATLJAUQM-UHFFFAOYSA-L 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 210000001758 mesenteric vein Anatomy 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- IZDROVVXIHRYMH-UHFFFAOYSA-N methanesulfonic anhydride Chemical compound CS(=O)(=O)OS(C)(=O)=O IZDROVVXIHRYMH-UHFFFAOYSA-N 0.000 description 1
- ITYJDNHFRZSTJY-UHFFFAOYSA-N methanesulfonyl bromide Chemical compound CS(Br)(=O)=O ITYJDNHFRZSTJY-UHFFFAOYSA-N 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- DASJFYAPNPUBGG-UHFFFAOYSA-N naphthalene-1-sulfonyl chloride Chemical compound C1=CC=C2C(S(=O)(=O)Cl)=CC=CC2=C1 DASJFYAPNPUBGG-UHFFFAOYSA-N 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 125000004430 oxygen atom Chemical group O* 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 229960001412 pentobarbital Drugs 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- ABUYPZMWYIVOKQ-UHFFFAOYSA-N phenyl carbonobromidate Chemical compound BrC(=O)OC1=CC=CC=C1 ABUYPZMWYIVOKQ-UHFFFAOYSA-N 0.000 description 1
- 229940067107 phenylethyl alcohol Drugs 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 description 1
- CPGRMGOILBSUQC-UHFFFAOYSA-N phosphoryl azide Chemical compound [N-]=[N+]=NP(=O)(N=[N+]=[N-])N=[N+]=[N-] CPGRMGOILBSUQC-UHFFFAOYSA-N 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229960003975 potassium Drugs 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 235000011181 potassium carbonates Nutrition 0.000 description 1
- 239000011698 potassium fluoride Substances 0.000 description 1
- 235000003270 potassium fluoride Nutrition 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 229940086066 potassium hydrogencarbonate Drugs 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- QQKDTTWZXHEGAQ-UHFFFAOYSA-N propyl carbonochloridate Chemical compound CCCOC(Cl)=O QQKDTTWZXHEGAQ-UHFFFAOYSA-N 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- 229960000957 prothipendyl Drugs 0.000 description 1
- 235000019423 pullulan Nutrition 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- 125000005624 silicic acid group Chemical class 0.000 description 1
- NGHMEZWZOZEZOH-UHFFFAOYSA-N silicic acid;hydrate Chemical compound O.O[Si](O)(O)O NGHMEZWZOZEZOH-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- IKFVLRLCFMEBDI-WDEREUQCSA-N tert-butyl (3r)-4-[[(2s)-1-hydroxypropan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-sulfanylidenebutanoate Chemical compound OC[C@H](C)NC(=S)[C@@H](CC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C IKFVLRLCFMEBDI-WDEREUQCSA-N 0.000 description 1
- PDAFIZPRSXHMCO-ZCFIWIBFSA-N tert-butyl n-[(2r)-1-hydroxypropan-2-yl]carbamate Chemical compound OC[C@@H](C)NC(=O)OC(C)(C)C PDAFIZPRSXHMCO-ZCFIWIBFSA-N 0.000 description 1
- SVULZUWODJYCNR-ZCFIWIBFSA-N tert-butyl n-[(2r)-1-nitrooxypropan-2-yl]carbamate Chemical compound [O-][N+](=O)OC[C@@H](C)NC(=O)OC(C)(C)C SVULZUWODJYCNR-ZCFIWIBFSA-N 0.000 description 1
- LQRGWGOFPUXNOV-ZETCQYMHSA-N tert-butyl n-[(2s)-1-hydroxybutan-2-yl]carbamate Chemical compound CC[C@@H](CO)NC(=O)OC(C)(C)C LQRGWGOFPUXNOV-ZETCQYMHSA-N 0.000 description 1
- PDAFIZPRSXHMCO-LURJTMIESA-N tert-butyl n-[(2s)-1-hydroxypropan-2-yl]carbamate Chemical compound OC[C@H](C)NC(=O)OC(C)(C)C PDAFIZPRSXHMCO-LURJTMIESA-N 0.000 description 1
- WJSQQDPUDMZYQM-VIFPVBQESA-N tert-butyl n-[(2s)-1-nitrooxyhexan-2-yl]carbamate Chemical compound CCCC[C@@H](CO[N+]([O-])=O)NC(=O)OC(C)(C)C WJSQQDPUDMZYQM-VIFPVBQESA-N 0.000 description 1
- SVULZUWODJYCNR-LURJTMIESA-N tert-butyl n-[(2s)-1-nitrooxypropan-2-yl]carbamate Chemical compound [O-][N+](=O)OC[C@H](C)NC(=O)OC(C)(C)C SVULZUWODJYCNR-LURJTMIESA-N 0.000 description 1
- WAOWQLJJQBDGQC-UHFFFAOYSA-N tetraazanium;tetrafluoride Chemical compound [NH4+].[NH4+].[NH4+].[NH4+].[F-].[F-].[F-].[F-] WAOWQLJJQBDGQC-UHFFFAOYSA-N 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Soil Working Implements (AREA)
- Supplying Of Containers To The Packaging Station (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4223795 | 1995-03-02 | ||
| JP27995195 | 1995-10-27 | ||
| PCT/JP1996/000487 WO1996026931A1 (fr) | 1995-03-02 | 1996-03-01 | Derives de thiazolidinone optiquement actifs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO974004D0 NO974004D0 (no) | 1997-09-01 |
| NO974004L NO974004L (no) | 1997-11-03 |
| NO309525B1 true NO309525B1 (no) | 2001-02-12 |
Family
ID=26381885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO974004A NO309525B1 (no) | 1995-03-02 | 1997-09-01 | Optisk aktive tiazolidinonderivater og farmasöytisk preparat inneholdende disse |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0812835B1 (de) |
| KR (1) | KR100292737B1 (de) |
| CN (1) | CN1066725C (de) |
| AT (1) | ATE201402T1 (de) |
| AU (1) | AU701977B2 (de) |
| CA (1) | CA2214386C (de) |
| CZ (1) | CZ290989B6 (de) |
| DE (1) | DE69612967T2 (de) |
| DK (1) | DK0812835T3 (de) |
| ES (1) | ES2158290T3 (de) |
| GR (1) | GR3036029T3 (de) |
| HK (2) | HK1003890A1 (de) |
| HU (1) | HU223094B1 (de) |
| NO (1) | NO309525B1 (de) |
| NZ (1) | NZ302391A (de) |
| PT (1) | PT812835E (de) |
| RU (1) | RU2141956C1 (de) |
| WO (1) | WO1996026931A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE203987T1 (de) * | 1994-12-15 | 2001-08-15 | Sankyo Co | Thiazolidonon- oder oxazolidinonderivate zur behandlung von angina pectoris und zusammensetzungen die diese als wirkstoffe enthält |
| WO2002069967A1 (fr) * | 2001-03-01 | 2002-09-12 | Sankyo Company, Limited | Compositions a absorption percutanee |
| EP1692121A1 (de) | 2003-11-18 | 2006-08-23 | University of Tennessee Research Foundation | Thiazolidinonamide, thiazolidincarbonsäureamide, herstellungsverfahren und anwendungen davon |
| TWI400220B (zh) | 2004-09-13 | 2013-07-01 | Takeda Pharmaceutical | 光活性胺衍生物的製法 |
| US9447049B2 (en) | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| DK2303021T3 (en) | 2008-06-16 | 2019-04-08 | Univ Tennessee Res Found | RELATIONSHIPS FOR TREATING CANCER |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| US8822513B2 (en) | 2010-03-01 | 2014-09-02 | Gtx, Inc. | Compounds for treatment of cancer |
| JP5879273B2 (ja) | 2010-03-01 | 2016-03-08 | ジーティーエックス・インコーポレイテッド | 癌を処置するための化合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8717068D0 (en) * | 1987-07-20 | 1987-08-26 | Fujisawa Pharmaceutical Co | Nitric ester derivative |
| US5298516A (en) * | 1991-03-27 | 1994-03-29 | Sankyo Company, Limited | Thiazolidone compounds and method of using the same as a vasodilator |
-
1996
- 1996-03-01 NZ NZ302391A patent/NZ302391A/en unknown
- 1996-03-01 CZ CZ19972734A patent/CZ290989B6/cs not_active IP Right Cessation
- 1996-03-01 DK DK96904292T patent/DK0812835T3/da active
- 1996-03-01 AU AU48438/96A patent/AU701977B2/en not_active Ceased
- 1996-03-01 CA CA002214386A patent/CA2214386C/en not_active Expired - Fee Related
- 1996-03-01 EP EP96904292A patent/EP0812835B1/de not_active Expired - Lifetime
- 1996-03-01 PT PT96904292T patent/PT812835E/pt unknown
- 1996-03-01 DE DE69612967T patent/DE69612967T2/de not_active Expired - Fee Related
- 1996-03-01 KR KR1019970706114A patent/KR100292737B1/ko not_active IP Right Cessation
- 1996-03-01 WO PCT/JP1996/000487 patent/WO1996026931A1/ja active IP Right Grant
- 1996-03-01 AT AT96904292T patent/ATE201402T1/de not_active IP Right Cessation
- 1996-03-01 CN CN96193568A patent/CN1066725C/zh not_active Expired - Fee Related
- 1996-03-01 HU HU9900320A patent/HU223094B1/hu not_active IP Right Cessation
- 1996-03-01 RU RU97114846A patent/RU2141956C1/ru not_active IP Right Cessation
- 1996-03-01 ES ES96904292T patent/ES2158290T3/es not_active Expired - Lifetime
-
1997
- 1997-09-01 NO NO974004A patent/NO309525B1/no not_active IP Right Cessation
-
1998
- 1998-04-15 HK HK98103110A patent/HK1003890A1/xx not_active IP Right Cessation
- 1998-09-28 HK HK98111023A patent/HK1016579A1/xx not_active IP Right Cessation
-
2001
- 2001-06-13 GR GR20010400882T patent/GR3036029T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2214386A1 (en) | 1996-09-06 |
| CN1183096A (zh) | 1998-05-27 |
| ATE201402T1 (de) | 2001-06-15 |
| NO974004D0 (no) | 1997-09-01 |
| KR100292737B1 (ko) | 2001-09-17 |
| HU223094B1 (hu) | 2004-03-29 |
| AU4843896A (en) | 1996-09-18 |
| HUP9900320A3 (en) | 1999-11-29 |
| CA2214386C (en) | 2001-12-04 |
| MX9706627A (es) | 1997-11-29 |
| WO1996026931A1 (fr) | 1996-09-06 |
| GR3036029T3 (en) | 2001-09-28 |
| EP0812835A1 (de) | 1997-12-17 |
| RU2141956C1 (ru) | 1999-11-27 |
| PT812835E (pt) | 2001-08-30 |
| DE69612967T2 (de) | 2002-04-04 |
| NO974004L (no) | 1997-11-03 |
| EP0812835B1 (de) | 2001-05-23 |
| DE69612967D1 (en) | 2001-06-28 |
| HK1003890A1 (en) | 1998-11-13 |
| DK0812835T3 (da) | 2001-07-09 |
| HK1016579A1 (en) | 1999-11-05 |
| EP0812835A4 (de) | 1998-04-29 |
| AU701977B2 (en) | 1999-02-11 |
| NZ302391A (en) | 1999-04-29 |
| CZ273497A3 (cs) | 1998-02-18 |
| ES2158290T3 (es) | 2001-09-01 |
| CN1066725C (zh) | 2001-06-06 |
| KR19980702707A (ko) | 1998-08-05 |
| CZ290989B6 (cs) | 2002-11-13 |
| HUP9900320A2 (hu) | 1999-05-28 |
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