NO20004528L - Cytostatiske midler - Google Patents
Cytostatiske midlerInfo
- Publication number
- NO20004528L NO20004528L NO20004528A NO20004528A NO20004528L NO 20004528 L NO20004528 L NO 20004528L NO 20004528 A NO20004528 A NO 20004528A NO 20004528 A NO20004528 A NO 20004528A NO 20004528 L NO20004528 L NO 20004528L
- Authority
- NO
- Norway
- Prior art keywords
- enoylamino
- ester
- hydroxycarbamoyl
- hex
- ethanoic acid
- Prior art date
Links
- 239000000824 cytostatic agent Substances 0.000 title abstract 2
- 229960003424 phenylacetic acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
2(R eller S)-[2R-(S-hydroksy-hydroksy- karbamoylmetyl)-4-merylpentanoylamin]-2-fenyl- etansyresykJopentylester; 2(R eller S)-(3S-hydroksy- karbamoyl-2R-isobutyl-heks-5-enoylamino)-2-fenyl- etansyreisopropylester; 2(R eller S)-[2R-(S-hydroksy- karbamoylmetoksvmetyl)-4-metylpentanoylamino]-3- fenyletansyresyklopentylester; 2(R eller S)-(3S- hydroksykarbarnoyl-2R-isobutyl-heks-5-enoylamino)- 2-(4-metoksyfenyl)etansyresyklopenrylester; 2(R eller S)-(3S-hydroksykarbamoyl-2R-isoburyl-heks-5-enoyl- amino)-2-(tien-2-yl)etansyresyklopentylester; og 2(R eller S)-(3S-hydroksykarbamoyl-2R-isobutyl- heks-5-enoylamino)-2-(tien-3-yl)etansyresyklo- pentylester er cytostatiske midler.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/GB1998/000754 WO1999046241A1 (en) | 1998-03-12 | 1998-03-12 | Cytostatic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20004528D0 NO20004528D0 (no) | 2000-09-11 |
NO20004528L true NO20004528L (no) | 2000-09-11 |
Family
ID=10825272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20004528A NO20004528L (no) | 1998-03-12 | 2000-09-11 | Cytostatiske midler |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1062202B1 (no) |
JP (1) | JP4324324B2 (no) |
KR (1) | KR20010041661A (no) |
CN (1) | CN1141292C (no) |
AT (1) | ATE231122T1 (no) |
AU (1) | AU747977B2 (no) |
BR (1) | BR9815717A (no) |
CA (1) | CA2323414C (no) |
CZ (1) | CZ299610B6 (no) |
DE (1) | DE69810817T2 (no) |
GB (1) | GB2349149A (no) |
HU (1) | HUP0100999A2 (no) |
IL (2) | IL137774A0 (no) |
NO (1) | NO20004528L (no) |
NZ (1) | NZ506293A (no) |
PL (1) | PL190637B1 (no) |
WO (1) | WO1999046241A1 (no) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9901863D0 (en) * | 1999-01-29 | 1999-03-17 | British Biotech Pharm | Antibacterial agents |
WO2019039937A1 (en) | 2017-08-21 | 2019-02-28 | Stichting Vumc | POLYTHERAPY FOR THE TREATMENT OF CANCER |
US10925851B2 (en) | 2018-03-15 | 2021-02-23 | Regents Of The University Of Minnesota | Use of Tosedostat and related compounds as analgesics |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993021942A2 (en) * | 1992-05-01 | 1993-11-11 | British Biotech Pharmaceuticals Limited | Use of mmp inhibitors |
GB9215665D0 (en) * | 1992-07-23 | 1992-09-09 | British Bio Technology | Compounds |
US5691381A (en) * | 1995-04-18 | 1997-11-25 | The Dupont Merck Pharmaceutical Company | Hydroxamic and carbocyclic acids as metalloprotease inhibitors |
EP0925278B1 (en) * | 1996-09-10 | 2002-07-17 | British Biotech Pharmaceuticals Limited | Cytostatic hydroxamic acid derivatives |
-
1998
- 1998-03-12 NZ NZ506293A patent/NZ506293A/en not_active IP Right Cessation
- 1998-03-12 CZ CZ20003317A patent/CZ299610B6/cs not_active IP Right Cessation
- 1998-03-12 AT AT98909620T patent/ATE231122T1/de not_active IP Right Cessation
- 1998-03-12 DE DE69810817T patent/DE69810817T2/de not_active Expired - Lifetime
- 1998-03-12 IL IL13777498A patent/IL137774A0/xx active IP Right Grant
- 1998-03-12 EP EP98909620A patent/EP1062202B1/en not_active Expired - Lifetime
- 1998-03-12 PL PL98342811A patent/PL190637B1/pl unknown
- 1998-03-12 CA CA002323414A patent/CA2323414C/en not_active Expired - Lifetime
- 1998-03-12 KR KR1020007009865A patent/KR20010041661A/ko not_active Application Discontinuation
- 1998-03-12 JP JP2000535622A patent/JP4324324B2/ja not_active Expired - Lifetime
- 1998-03-12 GB GB0019414A patent/GB2349149A/en not_active Withdrawn
- 1998-03-12 AU AU64106/98A patent/AU747977B2/en not_active Expired
- 1998-03-12 CN CNB988138476A patent/CN1141292C/zh not_active Expired - Lifetime
- 1998-03-12 BR BR9815717-5A patent/BR9815717A/pt unknown
- 1998-03-12 WO PCT/GB1998/000754 patent/WO1999046241A1/en not_active Application Discontinuation
- 1998-03-12 HU HU0100999A patent/HUP0100999A2/hu unknown
-
2000
- 2000-08-09 IL IL137774A patent/IL137774A/en not_active IP Right Cessation
- 2000-09-11 NO NO20004528A patent/NO20004528L/no unknown
Also Published As
Publication number | Publication date |
---|---|
NO20004528D0 (no) | 2000-09-11 |
ATE231122T1 (de) | 2003-02-15 |
GB0019414D0 (en) | 2000-09-27 |
CA2323414C (en) | 2008-05-13 |
PL342811A1 (en) | 2001-07-02 |
IL137774A0 (en) | 2001-10-31 |
CZ20003317A3 (cs) | 2001-03-14 |
GB2349149A (en) | 2000-10-25 |
AU6410698A (en) | 1999-09-27 |
JP4324324B2 (ja) | 2009-09-02 |
EP1062202B1 (en) | 2003-01-15 |
EP1062202A1 (en) | 2000-12-27 |
AU747977B2 (en) | 2002-05-30 |
CA2323414A1 (en) | 1999-09-16 |
NZ506293A (en) | 2003-05-30 |
CN1141292C (zh) | 2004-03-10 |
WO1999046241A1 (en) | 1999-09-16 |
CZ299610B6 (cs) | 2008-09-17 |
CN1286681A (zh) | 2001-03-07 |
JP2002506057A (ja) | 2002-02-26 |
PL190637B1 (pl) | 2005-12-30 |
KR20010041661A (ko) | 2001-05-25 |
BR9815717A (pt) | 2000-11-07 |
DE69810817D1 (de) | 2003-02-20 |
DE69810817T2 (de) | 2003-11-20 |
IL137774A (en) | 2006-07-05 |
HUP0100999A2 (hu) | 2001-08-28 |
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