IL137774A0 - Cytostatic agents - Google Patents

Cytostatic agents

Info

Publication number
IL137774A0
IL137774A0 IL13777498A IL13777498A IL137774A0 IL 137774 A0 IL137774 A0 IL 137774A0 IL 13777498 A IL13777498 A IL 13777498A IL 13777498 A IL13777498 A IL 13777498A IL 137774 A0 IL137774 A0 IL 137774A0
Authority
IL
Israel
Prior art keywords
hydroxycarbamoyl
enoylamino
hex
isobutyl
methyl
Prior art date
Application number
IL13777498A
Other languages
English (en)
Original Assignee
British Biotech Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharm filed Critical British Biotech Pharm
Publication of IL137774A0 publication Critical patent/IL137774A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL13777498A 1998-03-12 1998-03-12 Cytostatic agents IL137774A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB1998/000754 WO1999046241A1 (en) 1998-03-12 1998-03-12 Cytostatic agents

Publications (1)

Publication Number Publication Date
IL137774A0 true IL137774A0 (en) 2001-10-31

Family

ID=10825272

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13777498A IL137774A0 (en) 1998-03-12 1998-03-12 Cytostatic agents
IL137774A IL137774A (en) 1998-03-12 2000-08-09 Cytostatic substances

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL137774A IL137774A (en) 1998-03-12 2000-08-09 Cytostatic substances

Country Status (17)

Country Link
EP (1) EP1062202B1 (xx)
JP (1) JP4324324B2 (xx)
KR (1) KR20010041661A (xx)
CN (1) CN1141292C (xx)
AT (1) ATE231122T1 (xx)
AU (1) AU747977B2 (xx)
BR (1) BR9815717A (xx)
CA (1) CA2323414C (xx)
CZ (1) CZ299610B6 (xx)
DE (1) DE69810817T2 (xx)
GB (1) GB2349149A (xx)
HU (1) HUP0100999A2 (xx)
IL (2) IL137774A0 (xx)
NO (1) NO20004528L (xx)
NZ (1) NZ506293A (xx)
PL (1) PL190637B1 (xx)
WO (1) WO1999046241A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9901863D0 (en) 1999-01-29 1999-03-17 British Biotech Pharm Antibacterial agents
WO2019039937A1 (en) 2017-08-21 2019-02-28 Stichting Vumc POLYTHERAPY FOR THE TREATMENT OF CANCER
US10925851B2 (en) 2018-03-15 2021-02-23 Regents Of The University Of Minnesota Use of Tosedostat and related compounds as analgesics

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1002556A3 (en) * 1992-05-01 2001-01-10 British Biotech Pharmaceuticals Limited Use of MMP inhibitors
GB9215665D0 (en) * 1992-07-23 1992-09-09 British Bio Technology Compounds
US5691381A (en) * 1995-04-18 1997-11-25 The Dupont Merck Pharmaceutical Company Hydroxamic and carbocyclic acids as metalloprotease inhibitors
CA2265666C (en) * 1996-09-10 2008-01-15 British Biotech Pharmaceuticals Limited Cytostatic hydroxamic acid derivatives

Also Published As

Publication number Publication date
AU6410698A (en) 1999-09-27
CA2323414A1 (en) 1999-09-16
NZ506293A (en) 2003-05-30
CZ20003317A3 (cs) 2001-03-14
PL190637B1 (pl) 2005-12-30
JP2002506057A (ja) 2002-02-26
BR9815717A (pt) 2000-11-07
EP1062202A1 (en) 2000-12-27
PL342811A1 (en) 2001-07-02
EP1062202B1 (en) 2003-01-15
DE69810817T2 (de) 2003-11-20
CA2323414C (en) 2008-05-13
NO20004528D0 (no) 2000-09-11
KR20010041661A (ko) 2001-05-25
JP4324324B2 (ja) 2009-09-02
HUP0100999A2 (hu) 2001-08-28
CN1141292C (zh) 2004-03-10
WO1999046241A1 (en) 1999-09-16
NO20004528L (no) 2000-09-11
GB0019414D0 (en) 2000-09-27
CZ299610B6 (cs) 2008-09-17
AU747977B2 (en) 2002-05-30
IL137774A (en) 2006-07-05
ATE231122T1 (de) 2003-02-15
DE69810817D1 (de) 2003-02-20
CN1286681A (zh) 2001-03-07
GB2349149A (en) 2000-10-25

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed