NO20002422L - Penetrasjonsforsterkende og irritasjonssenkende systemer - Google Patents
Penetrasjonsforsterkende og irritasjonssenkende systemerInfo
- Publication number
- NO20002422L NO20002422L NO20002422A NO20002422A NO20002422L NO 20002422 L NO20002422 L NO 20002422L NO 20002422 A NO20002422 A NO 20002422A NO 20002422 A NO20002422 A NO 20002422A NO 20002422 L NO20002422 L NO 20002422L
- Authority
- NO
- Norway
- Prior art keywords
- penetration
- irritation
- enhancing
- lowering systems
- transdermal
- Prior art date
Links
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 abstract 2
- 238000012377 drug delivery Methods 0.000 abstract 2
- 230000000699 topical effect Effects 0.000 abstract 2
- 206010040880 Skin irritation Diseases 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 230000036556 skin irritation Effects 0.000 abstract 1
- 231100000475 skin irritation Toxicity 0.000 abstract 1
- 229960003604 testosterone Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6498097P | 1997-11-10 | 1997-11-10 | |
PCT/US1998/023750 WO1999024041A1 (en) | 1997-11-10 | 1998-11-09 | Penetration enhancing and irritation reducing systems |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20002422D0 NO20002422D0 (no) | 2000-05-10 |
NO20002422L true NO20002422L (no) | 2000-06-21 |
Family
ID=22059554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20002422A NO20002422L (no) | 1997-11-10 | 2000-05-10 | Penetrasjonsforsterkende og irritasjonssenkende systemer |
Country Status (17)
Country | Link |
---|---|
US (3) | US6319913B1 (es) |
EP (2) | EP1030668A4 (es) |
JP (2) | JP4139860B2 (es) |
KR (1) | KR100648536B1 (es) |
CN (1) | CN1172674C (es) |
AT (1) | ATE418988T1 (es) |
AU (1) | AU747041B2 (es) |
BR (1) | BR9814014B1 (es) |
CA (1) | CA2309688C (es) |
DE (1) | DE69840426D1 (es) |
DK (1) | DK1510213T3 (es) |
ES (1) | ES2318233T3 (es) |
IL (1) | IL136042A (es) |
NO (1) | NO20002422L (es) |
NZ (1) | NZ504423A (es) |
PT (1) | PT1510213E (es) |
WO (1) | WO1999024041A1 (es) |
Families Citing this family (126)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69840426D1 (de) * | 1997-11-10 | 2009-02-12 | Strakan Int Ltd | Penetrationsfördernde und irritationsvermindernde Systeme mit Testosteron |
US7179483B2 (en) * | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
CN102327253A (zh) * | 2000-04-26 | 2012-01-25 | 沃特森药物公司 | 最小化与奥昔布宁疗法有关的副作用 |
US7029694B2 (en) * | 2000-04-26 | 2006-04-18 | Watson Laboratories, Inc. | Compositions and methods for transdermal oxybutynin therapy |
US7897559B2 (en) * | 2000-06-29 | 2011-03-01 | Parks L Dean | Dermatological composition and kit containing avermectin compound for treating dermatological conditions |
US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
ATE485837T1 (de) | 2000-08-03 | 2010-11-15 | Antares Pharma Ipl Ag | Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert |
US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
JP2004507511A (ja) * | 2000-08-30 | 2004-03-11 | ユニメッド・ファーマシューティカルズ・インコーポレーテッド | 女性におけるテストステロンおよび近縁ステロイド濃度を増大させる方法 |
US20040002482A1 (en) * | 2000-08-30 | 2004-01-01 | Dudley Robert E. | Androgen pharmaceutical composition and method for treating depression |
NZ524601A (en) * | 2000-08-30 | 2006-04-28 | Unimed Pharmaceuticals Inc | Method for treating erectile dysfunction and increasing libido in men |
US20030139384A1 (en) * | 2000-08-30 | 2003-07-24 | Dudley Robert E. | Method for treating erectile dysfunction and increasing libido in men |
JP5039252B2 (ja) * | 2000-08-31 | 2012-10-03 | ユニメッド ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 性機能低下を治療するための医薬組成物及び方法 |
SK7932003A3 (en) * | 2000-12-22 | 2003-11-04 | August Wolff Gmbh & Co Dr | Gel composition and trans-scrotal application of a composition for the treatment of hypogonadism |
CA2451839C (en) * | 2001-06-22 | 2013-08-06 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions comprising peptides and permeation enhancers |
AU2002333193A1 (en) * | 2001-08-15 | 2003-03-03 | Leo Pharma A/S | A pharmaceutical composition for dermal application |
WO2003028667A2 (en) * | 2001-10-04 | 2003-04-10 | Cellegy Pharmaceuticals, Inc. | Semisolid topical hormonal compositions and methods for treatment |
EP1455697A4 (en) | 2001-12-20 | 2009-08-05 | Femmepharma Holding Co Inc | VAGINAL DRUG DELIVERY |
WO2004091631A1 (en) * | 2002-03-15 | 2004-10-28 | Unimed Pharmaceuticals, Inc. | Androgen pharmaceutical composition and method for treating depression |
BR0308584A (pt) * | 2002-03-15 | 2005-02-22 | Unimed Pharmaceuticals Inc | Composição farmacêutica androgênica e método para tratamento de depressão |
MY139721A (en) * | 2002-04-19 | 2009-10-30 | Cpex Pharmaceuticals Inc | Pharmaceutical composition |
US6959640B2 (en) * | 2002-06-06 | 2005-11-01 | Omega Patents, L.L.C. | Device for magnetically treating materials and associated methods |
JP5160018B2 (ja) | 2002-06-25 | 2013-03-13 | アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド | 非晶質医薬組成物を用いる経皮送達速度調節 |
US7099713B2 (en) | 2002-06-28 | 2006-08-29 | Battelle Memorial Institute | Skin conduction and transport systems |
IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
ES2532906T5 (es) | 2002-10-25 | 2022-03-23 | Foamix Pharmaceuticals Ltd | Espuma cosmética y farmacéutica |
US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
US8119109B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Foamable compositions, kits and methods for hyperhidrosis |
US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
US8119150B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
WO2004060322A2 (en) | 2003-01-02 | 2004-07-22 | Femmepharma Holding Company, Inc. | Pharmaceutical preparations for treatments of diseases and disorders of the breast |
US9173836B2 (en) | 2003-01-02 | 2015-11-03 | FemmeParma Holding Company, Inc. | Pharmaceutical preparations for treatments of diseases and disorders of the breast |
WO2004075822A2 (fr) * | 2003-02-20 | 2004-09-10 | Besins International Belgique | Composition pharmaceutique pour administration transdermique ou transmuqueuse |
FR2851470B1 (fr) * | 2003-02-20 | 2007-11-16 | Besins Int Belgique | Composition pharmaceutique pour administration transdermique ou transmuqueuse |
US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
US20040259852A1 (en) * | 2003-06-18 | 2004-12-23 | White Hillary D. | Trandsdermal compositions and methods for treatment of fibromyalgia and chronic fatigue syndrome |
US8883769B2 (en) | 2003-06-18 | 2014-11-11 | White Mountain Pharma, Inc. | Methods for the treatment of fibromyalgia and chronic fatigue syndrome |
US20050036953A1 (en) * | 2003-08-13 | 2005-02-17 | Moshe Arkin | Topical compositions of ammonium lactate |
US20050037040A1 (en) * | 2003-08-13 | 2005-02-17 | Moshe Arkin | Topical compositions of urea and ammonium lactate |
US20050042182A1 (en) * | 2003-08-13 | 2005-02-24 | Moshe Arkin | Topical compositions of urea |
FR2856926B1 (fr) * | 2003-07-02 | 2005-09-30 | Centre Nat Rech Scient | Utilisation des n-alkanols comme activateurs du canal cftr |
US20050042268A1 (en) * | 2003-07-16 | 2005-02-24 | Chaim Aschkenasy | Pharmaceutical composition and method for transdermal drug delivery |
US20050020552A1 (en) * | 2003-07-16 | 2005-01-27 | Chaim Aschkenasy | Pharmaceutical composition and method for transdermal drug delivery |
US20050025833A1 (en) * | 2003-07-16 | 2005-02-03 | Chaim Aschkenasy | Pharmaceutical composition and method for transdermal drug delivery |
US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
NZ546106A (en) | 2003-10-10 | 2008-10-31 | Antares Pharma Ipl Ag | Transdermal pharmaceutical formulation for minimizing skin residues |
US20050244502A1 (en) * | 2004-04-28 | 2005-11-03 | Mathias Neil R | Composition for enhancing absorption of a drug and method |
US7425340B2 (en) | 2004-05-07 | 2008-09-16 | Antares Pharma Ipl Ag | Permeation enhancing compositions for anticholinergic agents |
EP1634583A1 (en) * | 2004-09-09 | 2006-03-15 | Laboratoires Besins International | Testosterone gels comprising propylene glycol as penetration enhancer |
EP1802258A4 (en) | 2004-09-13 | 2015-09-23 | Chrono Therapeutics Inc | BIOSYNCHRONE TRANSDERMAL MEDICINES |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
US20070042026A1 (en) * | 2005-03-17 | 2007-02-22 | Wille John J | Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions |
WO2006127905A2 (en) | 2005-05-24 | 2006-11-30 | Chrono Therapeutics, Inc. | Portable drug delivery device |
US8067399B2 (en) | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
CN102091079B (zh) | 2005-06-03 | 2014-03-12 | 艾克若克斯Dds有限公司 | 用于透皮给药的方法和组合物 |
GB0518558D0 (en) * | 2005-09-12 | 2005-10-19 | Givaudan Sa | Improvements in or related to organic compounds |
ZA200803087B (en) | 2005-10-12 | 2009-11-25 | Unimed Pharmaceuticals Llc | Improved testosterone gel and method of use |
CN101426475A (zh) | 2006-04-21 | 2009-05-06 | 安塔雷斯制药Ipl股份公司 | 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法 |
US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
WO2008083158A2 (en) * | 2006-12-26 | 2008-07-10 | Femmepharma Holding Company, Inc. | Topical administration of danazol |
BRPI0720945A2 (pt) | 2007-01-11 | 2012-12-25 | Acrux Dds Pty Ltd | instrumento espalhador |
US9283177B2 (en) * | 2007-01-16 | 2016-03-15 | Juventio, Llc | Topical anesthetic for rapid local anesthesia and method of applying a topical anesthetic |
CA2675797A1 (en) * | 2007-01-16 | 2008-07-24 | Dermworx, Incorporated | Topical anesthetic for rapid local anesthesia and method of applying a topical anesthetic |
US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
WO2010041141A2 (en) | 2008-10-07 | 2010-04-15 | Foamix Ltd. | Oil-based foamable carriers and formulations |
WO2009090495A2 (en) | 2007-12-07 | 2009-07-23 | Foamix Ltd. | Oil and liquid silicone foamable carriers and formulations |
WO2009090558A2 (en) | 2008-01-14 | 2009-07-23 | Foamix Ltd. | Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses |
EP2278947A4 (en) * | 2008-05-21 | 2013-11-06 | Teikoku Pharma Usa Inc | TREATMENT OF DYSMENORRHEA BY TRANSDERMAL ADMINISTRATION OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS |
WO2010008600A1 (en) * | 2008-07-16 | 2010-01-21 | Dermworx Incorporated | Topical drug delivery system |
RU2011111206A (ru) * | 2008-10-31 | 2012-12-10 | Моберг Дерма Аб | Композиции для местного применения, содержащие комбинацию по меньшей мере двух агентов, усиливающих проникновение |
SI2373305T1 (sl) * | 2008-12-11 | 2017-09-29 | Besins Healthcare Luxembourg Sarl | Transdermalni farmacevtski sestavki, ki obsegajo serm |
CA2760186C (en) | 2009-04-28 | 2019-10-29 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
EP4249001A3 (en) | 2009-08-21 | 2023-11-29 | Novan, Inc. | Topical gels |
US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
CA2776474C (en) | 2009-10-02 | 2021-01-12 | Foamix Ltd. | Topical tetracycline compositions |
US10080760B2 (en) | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
US8174881B2 (en) | 2009-11-24 | 2012-05-08 | Micron Technology, Inc. | Techniques for reducing disturbance in a semiconductor device |
CN102309669B (zh) * | 2010-07-08 | 2013-07-03 | 高健生 | 一种治疗变态反应性结膜炎的中药制剂 |
EP2640398A4 (en) | 2010-11-18 | 2014-05-14 | White Mountain Pharma Inc | METHODS FOR TREATING CHRONIC OR REFRACTORY PAIN AND / OR INCREASING PAIN THRESHOLD IN A SUBJECT, AND ASSOCIATED PHARMACEUTICAL COMPOSITIONS |
US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
US20130040923A1 (en) | 2011-05-13 | 2013-02-14 | Trimel Pharmaceuticals Corporation | Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
KR20200118228A (ko) * | 2011-05-15 | 2020-10-14 | 에이세러스 바이오파마 인크. | 비내용 테스토스테론 바이오-접착제 겔 제형 및 남성의 성선기능저하증을 치료하기 위한 그의 용도 |
EP2729131B1 (en) | 2011-07-05 | 2020-04-15 | Novan, Inc. | Topical compositions |
CA2841785A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
CN102335390B (zh) * | 2011-09-30 | 2013-01-02 | 王巍 | 一种治疗面部湿疹的洗剂 |
US11077194B2 (en) | 2012-03-14 | 2021-08-03 | Novan, Inc. | Nitric oxide releasing pharmaceutical compositions |
US10105487B2 (en) | 2013-01-24 | 2018-10-23 | Chrono Therapeutics Inc. | Optimized bio-synchronous bioactive agent delivery system |
US9855211B2 (en) * | 2013-02-28 | 2018-01-02 | Novan, Inc. | Topical compositions and methods of using the same |
US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
US10206947B2 (en) | 2013-08-08 | 2019-02-19 | Novan, Inc. | Topical compositions and methods of using the same |
US11813284B2 (en) | 2013-08-08 | 2023-11-14 | Novan, Inc. | Topical compositions and methods of using the same |
USD750788S1 (en) | 2013-11-26 | 2016-03-01 | Acrux Dds Pty Ltd | Topical spreading applicator |
USD749225S1 (en) | 2013-11-26 | 2016-02-09 | Acrux Dds Pty Ltd | Topical spreading applicator |
US8785426B1 (en) | 2013-12-13 | 2014-07-22 | Upsher-Smith Laboratories, Inc. | Testosterone gel compositions and related methods |
US10322082B2 (en) | 2014-07-11 | 2019-06-18 | Novan, Inc. | Topical antiviral compositions and methods of using the same |
WO2016007834A1 (en) | 2014-07-11 | 2016-01-14 | Novan, Inc. | Topical antiviral compositions and methods of using the same |
JP2018511355A (ja) | 2015-01-28 | 2018-04-26 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 薬剤送達方法及びシステム |
CA2977814A1 (en) | 2015-03-12 | 2016-09-15 | Chrono Therapeutics Inc. | Craving input and support system |
US20170014417A1 (en) | 2015-07-14 | 2017-01-19 | Lipp Life Sciences Llc | Pharmaceutical administration system for the transdermal application of vardenafil |
JP6444956B2 (ja) * | 2015-09-30 | 2018-12-26 | 富士フイルム株式会社 | 経皮吸収用組成物 |
JP7090549B2 (ja) | 2016-03-02 | 2022-06-24 | ノヴァン,インコーポレイテッド | 炎症のための治療用組成物およびその治療方法 |
CN109310630A (zh) | 2016-04-13 | 2019-02-05 | 诺万公司 | 用于治疗感染的组合物、系统、试剂盒和方法 |
MX2017011630A (es) | 2016-09-08 | 2018-09-25 | Foamix Pharmaceuticals Ltd | Composiciones y metodos para tratar rosacea y acne. |
US11285306B2 (en) | 2017-01-06 | 2022-03-29 | Morningside Venture Investments Limited | Transdermal drug delivery devices and methods |
US10821075B1 (en) | 2017-07-12 | 2020-11-03 | James Blanchard | Compositions for topical application of a medicaments onto a mammalian body surface |
EP3758679A4 (en) | 2018-03-01 | 2021-12-15 | Novan, Inc. | NITRIC OXIDE RELEASING SUPPOSITORIES AND THEIR METHODS OF USE |
EP3801732A4 (en) | 2018-05-29 | 2022-04-27 | Morningside Venture Investments Limited | DRUG DELIVERY METHODS AND SYSTEMS |
AU2019365255A1 (en) | 2018-10-26 | 2021-06-03 | Viramal Limited | Mucoadhesive gel composition |
TW202305125A (zh) | 2021-04-30 | 2023-02-01 | 美商凱立凡爾免疫治療股份有限公司 | 用於經修飾mhc表現之溶瘤病毒 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US175329A (en) * | 1876-03-28 | Improvement in processes of preserving burial-cases | ||
CA1165240A (en) | 1980-07-09 | 1984-04-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions |
JPS59134710A (ja) | 1983-01-21 | 1984-08-02 | Suntory Ltd | 発酵養毛化粧料 |
US4552872A (en) | 1983-06-21 | 1985-11-12 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing corticosteroids |
US4557934A (en) * | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
US4537776A (en) * | 1983-06-21 | 1985-08-27 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
JPS6067409A (ja) | 1983-09-22 | 1985-04-17 | Suntory Ltd | 頭髪用化粧料 |
US4743588A (en) * | 1984-06-13 | 1988-05-10 | Allergan Pharmaceuticals, Inc. | Compositions and methods of enhancing transdermal and transmembrane penetration systemic agents |
US5196410A (en) * | 1986-10-31 | 1993-03-23 | Pfizer Inc. | Transdermal flux enhancing compositions |
US4863970A (en) * | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
ATE77559T1 (de) * | 1986-11-14 | 1992-07-15 | Theratech Inc | Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems. |
CA1331137C (en) * | 1988-02-29 | 1994-08-02 | Pfizer, Inc. | Transdermal flux enhancing compositions |
US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
US4855294A (en) * | 1988-09-06 | 1989-08-08 | Theratech, Inc. | Method for reducing skin irritation associated with drug/penetration enhancer compositions |
EP0371496A1 (en) * | 1988-12-01 | 1990-06-06 | Schering Corporation | Compositions for transdermal delivery of estradiol |
EP0416173B1 (en) * | 1989-08-23 | 1997-01-15 | Hitachi, Ltd. | A method for adjusting network parameters in a multi-layer perceptron device, and perceptron device provided with means for executing the method |
US5152997A (en) * | 1990-12-11 | 1992-10-06 | Theratech, Inc. | Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels |
DE69231536T2 (de) * | 1991-08-26 | 2001-06-13 | Abbott Lab | Verbindungen und methoden zur sublingualen oder buccalen verabreichung von therapeutischen agentien |
KR950701508A (ko) * | 1992-06-11 | 1995-04-28 | 챨스 디 에버트 | 경피식 약물수송을 조절하기 위한 글리세린의 용도(the use of glycerin in moderating transdermal drug delivery) |
US5607691A (en) * | 1992-06-12 | 1997-03-04 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
AU2345695A (en) * | 1994-04-28 | 1995-11-29 | F. Hoffmann-La Roche Ag | Pharmaceutical composition for transdermal delivery |
US5601839A (en) * | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
US5780050A (en) * | 1995-07-20 | 1998-07-14 | Theratech, Inc. | Drug delivery compositions for improved stability of steroids |
AU1429697A (en) * | 1995-12-29 | 1997-07-28 | Cygnus, Inc. | Systems and methods for the transdermal administration of androgenic agents |
IT1283102B1 (it) * | 1996-06-06 | 1998-04-07 | Permatec Nv | Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele |
US5760096A (en) | 1996-10-18 | 1998-06-02 | Thornfeldt; Carl R. | Potent penetration enhancers |
BR9712474A (pt) * | 1996-10-30 | 1999-10-26 | Theratech Inc | steres de ácido graxo de sais de ácido láctico como melhoradores de permeação |
DE69840426D1 (de) * | 1997-11-10 | 2009-02-12 | Strakan Int Ltd | Penetrationsfördernde und irritationsvermindernde Systeme mit Testosteron |
US6465009B1 (en) | 1998-03-18 | 2002-10-15 | Yamanouchi Pharmaceutical Co., Ltd. | Water soluble polymer-based rapidly dissolving tablets and production processes thereof |
WO2003028667A2 (en) | 2001-10-04 | 2003-04-10 | Cellegy Pharmaceuticals, Inc. | Semisolid topical hormonal compositions and methods for treatment |
-
1998
- 1998-11-09 DE DE69840426T patent/DE69840426D1/de not_active Expired - Lifetime
- 1998-11-09 CN CNB988130491A patent/CN1172674C/zh not_active Expired - Fee Related
- 1998-11-09 DK DK04028426T patent/DK1510213T3/da active
- 1998-11-09 KR KR1020007005094A patent/KR100648536B1/ko active IP Right Grant
- 1998-11-09 IL IL13604298A patent/IL136042A/xx not_active IP Right Cessation
- 1998-11-09 WO PCT/US1998/023750 patent/WO1999024041A1/en active IP Right Grant
- 1998-11-09 PT PT04028426T patent/PT1510213E/pt unknown
- 1998-11-09 EP EP98956663A patent/EP1030668A4/en not_active Withdrawn
- 1998-11-09 US US09/189,090 patent/US6319913B1/en not_active Expired - Lifetime
- 1998-11-09 CA CA002309688A patent/CA2309688C/en not_active Expired - Fee Related
- 1998-11-09 AU AU13132/99A patent/AU747041B2/en not_active Ceased
- 1998-11-09 EP EP04028426A patent/EP1510213B1/en not_active Revoked
- 1998-11-09 ES ES04028426T patent/ES2318233T3/es not_active Expired - Lifetime
- 1998-11-09 NZ NZ504423A patent/NZ504423A/xx not_active IP Right Cessation
- 1998-11-09 AT AT04028426T patent/ATE418988T1/de active
- 1998-11-09 BR BRPI9814014-0A patent/BR9814014B1/pt not_active IP Right Cessation
- 1998-11-09 JP JP2000520133A patent/JP4139860B2/ja not_active Expired - Fee Related
-
2000
- 2000-05-10 NO NO20002422A patent/NO20002422L/no not_active Application Discontinuation
-
2001
- 2001-09-24 US US09/963,287 patent/US6579865B2/en not_active Expired - Lifetime
-
2003
- 2003-03-12 US US10/389,715 patent/US7157097B2/en not_active Expired - Lifetime
-
2004
- 2004-10-28 JP JP2004313201A patent/JP2005047932A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2309688C (en) | 2007-04-24 |
JP2005047932A (ja) | 2005-02-24 |
IL136042A (en) | 2005-12-18 |
EP1510213A3 (en) | 2005-03-23 |
CN1172674C (zh) | 2004-10-27 |
AU1313299A (en) | 1999-05-31 |
ES2318233T3 (es) | 2009-05-01 |
ATE418988T1 (de) | 2009-01-15 |
DK1510213T3 (da) | 2009-03-23 |
KR100648536B1 (ko) | 2006-11-24 |
US20020058650A1 (en) | 2002-05-16 |
EP1510213A2 (en) | 2005-03-02 |
EP1030668A1 (en) | 2000-08-30 |
NZ504423A (en) | 2003-04-29 |
JP2001522804A (ja) | 2001-11-20 |
WO1999024041A1 (en) | 1999-05-20 |
DE69840426D1 (de) | 2009-02-12 |
US6319913B1 (en) | 2001-11-20 |
PT1510213E (pt) | 2009-02-12 |
AU747041C (en) | 1999-05-31 |
US7157097B2 (en) | 2007-01-02 |
IL136042A0 (en) | 2001-05-20 |
KR20010031984A (ko) | 2001-04-16 |
EP1030668A4 (en) | 2002-09-25 |
AU747041B2 (en) | 2002-05-09 |
CA2309688A1 (en) | 1999-05-20 |
NO20002422D0 (no) | 2000-05-10 |
CN1285749A (zh) | 2001-02-28 |
US20030166625A1 (en) | 2003-09-04 |
US6579865B2 (en) | 2003-06-17 |
BR9814014A (pt) | 2000-09-26 |
EP1510213B1 (en) | 2008-12-31 |
BR9814014B1 (pt) | 2014-10-07 |
JP4139860B2 (ja) | 2008-08-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20002422D0 (no) | Penetrasjonsforsterkende og irritasjonssenkende systemer | |
ATE244003T1 (de) | Transdermales therapeutisches system | |
MY109727A (en) | Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals | |
BR0312506A (pt) | Composições transdérmicas de toxina botulìnica | |
DE59603597D1 (de) | Therapeutische zubereitung zur transdermalen applikation von wirkstoffen durch die haut | |
NO973900L (no) | Nitrogenoksyd syntase inhibitor | |
BR0300830A (pt) | Composições tópicas anticâncer e métodos de uso destas | |
BR9900501A (pt) | Utilização de amido e processo de tratamento cosmético. | |
DK0513832T3 (da) | Anvendelse af dibutyladipat og isopropylmyristat i topiske og transdermale produkter | |
ATE77230T1 (de) | Melatoninhaltige mittel sowie deren verwendungen. | |
BR0200921A (pt) | Uso de produtos de legume para o tratamento de agressões externas | |
ATE526944T1 (de) | Selbstbräunungszusammensetzungen die cholesterolsulfat und dha enthalten | |
DE9312509U1 (de) | Präparate zur äußeren Verabreichung von antiseptischen und/oder die Wundheilung fördernden Wirkstoffen | |
ATE52911T1 (de) | Topische anwendung des 3-phenylacetylamino-2,6piperidindionszur behandlung von hautfalten und hyperpigmentierung. | |
MX9805290A (es) | Utilizacion de inhibidores de la actividad del acido retinoico para tratar las pieles sensibles y/o los daños agudos inducidos por las radiaciones ultravioleta. | |
WO1997030714A3 (en) | Topical pharmaceutical composition containing heparin | |
DK131586A (da) | Transdermalt, antiallergisk, farmaceutisk praeparat | |
GR3031890T3 (en) | Use of topically applied factor xiii for inhibiting hemorrhage. | |
TR199802703T2 (xx) | HIV tedavisinde Vx478, Zidov�din, ve/veya 1592U89 i�eren kombinasyonlar�n kullan�m�. | |
ATE271872T1 (de) | Topische carbamazepin-formulierungen und deren verwendung | |
PT89986A (pt) | Processo de preparacao de preparacoes topicas a base de griseofulvina | |
ATE289818T1 (de) | Transdermales therapeutisches system mit einer östriol enthaltenden bisphosphatekombination | |
SE9900891D0 (sv) | Topical composition for dermatological and cosmetic treatment of the skin | |
GEP20012408B (en) | Means for Treatment of Psoriasis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |