NO178858C - Analogifremgangsmåte for fremstilling av substituerte 4-fenyl-4-piperidinkarboksamider med både lokal anestetisk og analgetisk effekt - Google Patents
Analogifremgangsmåte for fremstilling av substituerte 4-fenyl-4-piperidinkarboksamider med både lokal anestetisk og analgetisk effektInfo
- Publication number
- NO178858C NO178858C NO922380A NO922380A NO178858C NO 178858 C NO178858 C NO 178858C NO 922380 A NO922380 A NO 922380A NO 922380 A NO922380 A NO 922380A NO 178858 C NO178858 C NO 178858C
- Authority
- NO
- Norway
- Prior art keywords
- piperidinecarboxamides
- phenyl
- local anesthetic
- analgesic effect
- analogous process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cosmetics (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8904298A SE8904298D0 (sv) | 1989-12-21 | 1989-12-21 | New compounds |
| PCT/SE1990/000818 WO1991009845A1 (en) | 1989-12-21 | 1990-12-17 | Substituted 4-phenyl-4-piperidinecarboxamides with both local anaesthetic and analgesic effect as well as processes for their preparation |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO922380L NO922380L (no) | 1992-06-17 |
| NO922380D0 NO922380D0 (no) | 1992-06-17 |
| NO178858B NO178858B (no) | 1996-03-11 |
| NO178858C true NO178858C (no) | 1996-06-19 |
Family
ID=20377821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO922380A NO178858C (no) | 1989-12-21 | 1992-06-17 | Analogifremgangsmåte for fremstilling av substituerte 4-fenyl-4-piperidinkarboksamider med både lokal anestetisk og analgetisk effekt |
Country Status (40)
| Country | Link |
|---|---|
| US (2) | US5227389A (ru) |
| EP (1) | EP0506778B1 (ru) |
| JP (1) | JP2656152B2 (ru) |
| KR (1) | KR0179382B1 (ru) |
| CN (1) | CN1037841C (ru) |
| AT (1) | ATE138650T1 (ru) |
| AU (1) | AU647068B2 (ru) |
| BG (1) | BG60912B1 (ru) |
| BR (1) | BR1100379A (ru) |
| CA (1) | CA2069608C (ru) |
| CZ (1) | CZ278035B6 (ru) |
| DE (1) | DE69027221T2 (ru) |
| DK (1) | DK0506778T3 (ru) |
| DZ (1) | DZ1468A1 (ru) |
| EG (1) | EG19361A (ru) |
| ES (1) | ES2087280T3 (ru) |
| FI (1) | FI100881B (ru) |
| HK (1) | HK22997A (ru) |
| HR (1) | HRP920591B1 (ru) |
| HU (1) | HU213110B (ru) |
| IE (1) | IE74855B1 (ru) |
| IL (1) | IL96636A (ru) |
| IS (1) | IS1664B (ru) |
| LT (1) | LT4005B (ru) |
| LV (2) | LV10949B (ru) |
| NO (1) | NO178858C (ru) |
| NZ (1) | NZ236293A (ru) |
| PL (1) | PL163591B1 (ru) |
| PT (1) | PT96303B (ru) |
| RO (1) | RO112864B1 (ru) |
| RU (1) | RU2039043C1 (ru) |
| SA (1) | SA91110209B1 (ru) |
| SE (1) | SE8904298D0 (ru) |
| SG (1) | SG46413A1 (ru) |
| SI (1) | SI9012346B (ru) |
| SK (1) | SK658190A3 (ru) |
| UA (1) | UA26403A (ru) |
| WO (1) | WO1991009845A1 (ru) |
| YU (1) | YU48086B (ru) |
| ZA (1) | ZA909903B (ru) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3916092B2 (ja) * | 1993-09-17 | 2007-05-16 | 杏林製薬株式会社 | イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬 |
| SE9400447D0 (sv) * | 1994-02-11 | 1994-02-11 | Astra Ab | New compounds |
| SE9404438D0 (sv) * | 1994-12-21 | 1994-12-21 | Astra Ab | New process |
| US5931809A (en) | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
| US7799337B2 (en) | 1997-07-21 | 2010-09-21 | Levin Bruce H | Method for directed intranasal administration of a composition |
| US20020102291A1 (en) * | 1997-12-15 | 2002-08-01 | Noven Pharmaceuticals, Inc. | Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
| CA2443672C (en) * | 2001-04-12 | 2011-03-29 | Pharmacopeia, Inc. | Aryl and biaryl piperidines used as mch antagonists |
| MXPA05006354A (es) * | 2002-12-13 | 2005-08-26 | Smithkline Beecham Corp | Antagonistas ccr5 como agentes terapeuticos. |
| AR063275A1 (es) * | 2006-10-12 | 2009-01-14 | Epix Delaware Inc | Compuestos de carboxamida, una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento de enfermedades mediadas por la activacion de ccr2. |
| WO2009076512A1 (en) | 2007-12-11 | 2009-06-18 | Epix Delaware, Inc. | Carboxamidξ compounds and their use as chemokine receptor agonists |
| US8473062B2 (en) | 2008-05-01 | 2013-06-25 | Autonomic Technologies, Inc. | Method and device for the treatment of headache |
| US8412336B2 (en) | 2008-12-29 | 2013-04-02 | Autonomic Technologies, Inc. | Integrated delivery and visualization tool for a neuromodulation system |
| US9320908B2 (en) | 2009-01-15 | 2016-04-26 | Autonomic Technologies, Inc. | Approval per use implanted neurostimulator |
| US8494641B2 (en) | 2009-04-22 | 2013-07-23 | Autonomic Technologies, Inc. | Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism |
| US20220096452A1 (en) | 2019-01-22 | 2022-03-31 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Local anesthetic for the treatment of neurological symptoms resulting from brain dysfunctions |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE96980C1 (ru) | ||||
| US2486796A (en) * | 1943-06-25 | 1949-11-01 | Ciba Pharm Prod Inc | Esters of 1-alkyl-4-hydroxyphenylpiperidyl-4-ketones |
| US3334106A (en) * | 1964-10-20 | 1967-08-01 | Aldrich Chem Co Inc | N(aryl)n(hydrocarbyl)-omega-(4-phenyl-4-piperidinocarbonylheteroamine) alkanoamide |
| US3539580A (en) * | 1967-06-26 | 1970-11-10 | Janssen Pharm | 4-aryl-4-aminoalkoxy-piperidines |
| CH498836A (de) * | 1968-12-20 | 1970-11-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Piperidinderivaten |
| US3737538A (en) * | 1968-12-30 | 1973-06-05 | Ciba Geigy Corp | Antitussive compositions and method with isonipecotic acid derivatives |
| FR2156470A2 (en) * | 1971-10-21 | 1973-06-01 | Synthelabo | 1-(3,3-diphenyl-1-propyl)-4-aryl-piperidines - as analgesics spasmolytic and anti-tussive agents |
| ZA899436B (en) * | 1988-12-12 | 1990-08-29 | Ciba Geigy | Piperidine derivatives |
| US5100903A (en) * | 1989-05-12 | 1992-03-31 | Anaquest, Inc. | N-aryl-n-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds |
-
1989
- 1989-12-21 SE SE8904298A patent/SE8904298D0/xx unknown
-
1990
- 1990-11-30 NZ NZ236293A patent/NZ236293A/xx unknown
- 1990-12-10 ZA ZA909903A patent/ZA909903B/xx unknown
- 1990-12-11 IL IL9663690A patent/IL96636A/en not_active IP Right Cessation
- 1990-12-12 DZ DZ900223A patent/DZ1468A1/xx active
- 1990-12-12 YU YU234690A patent/YU48086B/sh unknown
- 1990-12-12 SI SI9012346A patent/SI9012346B/sl not_active IP Right Cessation
- 1990-12-17 SG SG1996004491A patent/SG46413A1/en unknown
- 1990-12-17 KR KR1019920701484A patent/KR0179382B1/ko not_active IP Right Cessation
- 1990-12-17 HU HU9202044A patent/HU213110B/hu unknown
- 1990-12-17 JP JP3501896A patent/JP2656152B2/ja not_active Expired - Fee Related
- 1990-12-17 IS IS3659A patent/IS1664B/is unknown
- 1990-12-17 DE DE69027221T patent/DE69027221T2/de not_active Expired - Fee Related
- 1990-12-17 IE IE453490A patent/IE74855B1/en not_active IP Right Cessation
- 1990-12-17 AU AU69783/91A patent/AU647068B2/en not_active Ceased
- 1990-12-17 DK DK91901571.9T patent/DK0506778T3/da active
- 1990-12-17 RO RO92-0832A patent/RO112864B1/ro unknown
- 1990-12-17 CA CA002069608A patent/CA2069608C/en not_active Expired - Fee Related
- 1990-12-17 ES ES91901571T patent/ES2087280T3/es not_active Expired - Lifetime
- 1990-12-17 WO PCT/SE1990/000818 patent/WO1991009845A1/en active IP Right Grant
- 1990-12-17 EP EP91901571A patent/EP0506778B1/en not_active Expired - Lifetime
- 1990-12-17 UA UA5052485A patent/UA26403A/uk unknown
- 1990-12-17 AT AT91901571T patent/ATE138650T1/de not_active IP Right Cessation
- 1990-12-20 PT PT96303A patent/PT96303B/pt active IP Right Grant
- 1990-12-20 EG EG74690A patent/EG19361A/xx active
- 1990-12-21 PL PL90288409A patent/PL163591B1/pl not_active IP Right Cessation
- 1990-12-21 CZ CS906581A patent/CZ278035B6/cs not_active IP Right Cessation
- 1990-12-21 US US07/633,246 patent/US5227389A/en not_active Expired - Lifetime
- 1990-12-21 SK SK6581-90A patent/SK658190A3/sk unknown
- 1990-12-21 CN CN90106009A patent/CN1037841C/zh not_active Expired - Fee Related
-
1991
- 1991-01-09 SA SA91110209A patent/SA91110209B1/ar unknown
-
1992
- 1992-06-17 FI FI922806A patent/FI100881B/fi not_active IP Right Cessation
- 1992-06-17 NO NO922380A patent/NO178858C/no unknown
- 1992-06-19 RU SU925052485A patent/RU2039043C1/ru not_active IP Right Cessation
- 1992-06-19 BG BG96513A patent/BG60912B1/bg unknown
- 1992-09-29 HR HRP-2346/90A patent/HRP920591B1/xx not_active IP Right Cessation
-
1993
- 1993-07-12 US US08/090,416 patent/US5360805A/en not_active Expired - Lifetime
- 1993-08-27 LV LVP-93-1042A patent/LV10949B/lv unknown
- 1993-12-30 LT LTIP1731A patent/LT4005B/lt not_active IP Right Cessation
-
1996
- 1996-07-17 LV LV960262A patent/LV5766B4/xx unknown
-
1997
- 1997-02-27 HK HK22997A patent/HK22997A/xx not_active IP Right Cessation
- 1997-04-30 BR BR1100379-0A patent/BR1100379A/pt active IP Right Grant
Also Published As
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