NO177638C - Analogifremgangsmåte for fremstilling av en terapeutisk aktiv spiroforbindelse - Google Patents

Analogifremgangsmåte for fremstilling av en terapeutisk aktiv spiroforbindelse

Info

Publication number
NO177638C
NO177638C NO893453A NO893453A NO177638C NO 177638 C NO177638 C NO 177638C NO 893453 A NO893453 A NO 893453A NO 893453 A NO893453 A NO 893453A NO 177638 C NO177638 C NO 177638C
Authority
NO
Norway
Prior art keywords
preparing
spiro compound
therapeutically active
analogous process
active spiro
Prior art date
Application number
NO893453A
Other languages
English (en)
Norwegian (no)
Other versions
NO177638B (no
NO893453D0 (no
NO893453L (no
Inventor
Isao Hayakawa
Shohgo Atarashi
Masazumi Imamura
Youichi Kimura
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of NO893453D0 publication Critical patent/NO893453D0/no
Publication of NO893453L publication Critical patent/NO893453L/no
Publication of NO177638B publication Critical patent/NO177638B/no
Publication of NO177638C publication Critical patent/NO177638C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Luminescent Compositions (AREA)
  • Dental Preparations (AREA)
  • Saccharide Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO893453A 1988-08-31 1989-08-29 Analogifremgangsmåte for fremstilling av en terapeutisk aktiv spiroforbindelse NO177638C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP21763888 1988-08-31
JP23131888 1988-09-14
JP29698588 1988-11-24
JP15631689 1989-06-19

Publications (4)

Publication Number Publication Date
NO893453D0 NO893453D0 (no) 1989-08-29
NO893453L NO893453L (no) 1990-03-01
NO177638B NO177638B (no) 1995-07-17
NO177638C true NO177638C (no) 1995-10-25

Family

ID=27473404

Family Applications (1)

Application Number Title Priority Date Filing Date
NO893453A NO177638C (no) 1988-08-31 1989-08-29 Analogifremgangsmåte for fremstilling av en terapeutisk aktiv spiroforbindelse

Country Status (19)

Country Link
US (1) US5508428A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP0529688B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (2) KR0148688B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1036193C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE160141T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU619891B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1336090C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE68928447T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK174689B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES2061845T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI92703C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (2) IE82128B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL91474A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN170262B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY104652A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO177638C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ230484A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH31278A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT91602B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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US5137892A (en) * 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
DK0641339T3 (da) * 1991-06-19 1999-12-20 Pfizer Antibakterielle midler med azaspiroquinolon
US5276041A (en) * 1991-11-08 1994-01-04 Kaken Pharmaceutical Co., Ltd. Oxime derivatives
EP0550016A1 (en) * 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and processes for preparing same
KR960011370B1 (ko) * 1991-12-31 1996-08-22 재단법인 한국화학연구소 스피로알킬아민 유도체와 그의 제조방법
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
DK0688772T3 (da) * 1994-06-16 1999-11-01 Lg Chemical Ltd Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling
EP1148047A3 (en) 1995-05-26 2004-10-06 Daiichi Pharmaceutical Co., Ltd. Processes for preparing cyclic compounds
NZ286951A (en) * 1995-07-13 1998-02-26 Anormed Inc Substituted Under N-n-diethyl-8,8-dipropyl-2-azaspiro[4,5]decane-2-propanamine dimaleate
TW519542B (en) * 1996-09-27 2003-02-01 Daiichi Seiyaku Co Bicyclic amine derivative
US20020032216A1 (en) * 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
MA24500A1 (fr) * 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
WO1999000393A1 (en) * 1997-06-26 1999-01-07 Dong Wha Pharmaceutical Industrial Co., Ltd. Quinolone carboxylic acid derivatives
DE19751948A1 (de) 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
DE60135640D1 (de) * 2000-02-09 2008-10-16 Daiichi Sankyo Co Ltd Rielle mittel die pyridincarbonsäuren als aktiven wirkstoff enthalten
EP1310487B1 (en) 2000-08-08 2007-01-03 Daiichi Pharmaceutical Co., Ltd. Processes for preparation of bicyclic compounds and intermediates therefor
JP4108311B2 (ja) * 2001-10-02 2008-06-25 ダイセル化学工業株式会社 １−アシル−１−シクロプロパンカルボン酸エステル誘導体の製造法
JP2003171354A (ja) 2001-12-06 2003-06-20 Daicel Chem Ind Ltd 光学活性アミン化合物又はその塩の製造方法
WO2005026145A2 (en) * 2003-09-12 2005-03-24 Warner-Lambert Company Llc Quinolone antibacterial agents
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
US7977346B2 (en) 2006-01-17 2011-07-12 Guoqing Paul Chen Spiro compounds and methods of use
EP2249828A1 (en) * 2008-01-07 2010-11-17 Janssen Pharmaceutica, N.V. Preparation of sulfamide derivatives
KR20140059164A (ko) 2011-03-15 2014-05-15 트라이우스 테라퓨틱스, 아이엔씨. 트라이사이클릭 자이라제 억제제
WO2012150221A2 (de) 2011-05-04 2012-11-08 Bayer Cropscience Ag Neue halogenierte benzylalkoholester der cyclopropancarbonsäure als schädlingsbekämpfungsmittel
WO2012150208A1 (de) 2011-05-04 2012-11-08 Bayer Cropscience Ag Verwendung von substituierten benzylalkoholestern der cyclopropancarbonsäure zur bekämpfung von insektizid-resistenten insekten
CN103073481A (zh) * 2013-02-06 2013-05-01 上海药明康德新药开发有限公司 一种4-氮杂螺[2.4]庚烷盐酸盐的制备方法
US20200369611A1 (en) * 2017-08-01 2020-11-26 Boehringer Ingelheim International Gmbh Intermediate compounds and methods

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US2814622A (en) * 1955-07-18 1957-11-26 Upjohn Co Organic compounds
GB984119A (en) * 1960-06-20 1965-02-24 Aspro Nicholas Ltd Substituted piperidines and methods for their preparation
US3418324A (en) * 1961-03-13 1968-12-24 Geschickter Fund Med Res Heterocyclic secondary amines
NL124128C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1963-05-27
DE1961474A1 (de) * 1968-12-19 1970-07-02 Leuna Werke Veb Verfahren zur Herstellung von am Stickstoff unsubstituierten Oxaziridinen
US3859292A (en) * 1972-08-15 1975-01-07 Scm Corp N-haloacyl (2-spirocycloaliphatic) oxazolidines
US4011233A (en) * 1973-06-28 1977-03-08 Givaudan Corporation 2-methyl-2-(4-methyl-3-pentene-1-yl) thiazolidine
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DD152706A5 (de) * 1980-08-21 1981-12-09 Stauffer Chemical Co Unkrautvertilgungsmittelzusammensetzung
US4777175A (en) * 1982-09-09 1988-10-11 Warner-Lambert Company Antibacterial agents
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DE3322530A1 (de) * 1983-06-23 1985-01-10 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
DE3721745A1 (de) * 1986-07-04 1988-01-14 Lentia Gmbh Bicyclisch substituierte chinoloncarbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
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WO1989000158A1 (en) * 1987-07-02 1989-01-12 Pfizer Inc. Bridged-diazabicycloalkyl quinolone carboxylic acids and esters
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JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤

Also Published As

Publication number Publication date
US5508428A (en) 1996-04-16
DK426289A (da) 1990-03-01
HK1003000A1 (en) 1998-09-30
KR0148719B1 (en) 1998-08-17
CN1100095A (zh) 1995-03-15
EP0529688B1 (en) 1997-11-12
IE82128B1 (en) 2002-02-20
DE68928447T2 (de) 1998-06-18
FI894045A0 (fi) 1989-08-29
EP0529688A2 (en) 1993-03-03
ATE160141T1 (de) 1997-11-15
FI894045A7 (fi) 1990-03-01
IL91474A0 (en) 1990-04-29
DE68910441T2 (de) 1994-03-03
EP0529688A3 (en) 1993-03-10
NO177638B (no) 1995-07-17
DE68928447D1 (de) 1997-12-18
IE930570L (en) 1990-02-28
CN1036193C (zh) 1997-10-22
IN170262B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-03-07
NO893453D0 (no) 1989-08-29
NZ230484A (en) 1991-06-25
FI92703B (fi) 1994-09-15
IL91474A (en) 1994-05-30
PT91602B (pt) 1995-05-31
AU4100689A (en) 1990-03-08
IE892785L (en) 1990-02-28
MY104652A (en) 1994-05-31
IE63492B1 (en) 1995-05-03
DE68910441D1 (de) 1993-12-09
PT91602A (pt) 1990-03-08
KR900003152A (ko) 1990-03-23
DK426289D0 (da) 1989-08-30
EP0357047B1 (en) 1993-11-03
FI92703C (fi) 1994-12-27
ES2061845T3 (es) 1994-12-16
CA1336090C (en) 1995-06-27
KR0148688B1 (ko) 1998-08-17
NO893453L (no) 1990-03-01
PH31278A (en) 1998-07-06
DK174689B1 (da) 2003-09-15
EP0357047A1 (en) 1990-03-07
AU619891B2 (en) 1992-02-06
ES2111029T3 (es) 1998-03-01

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