NO178188C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 4,5,6,7-tetrahydro-benzimidazolderivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 4,5,6,7-tetrahydro-benzimidazolderivater

Info

Publication number
NO178188C
NO178188C NO895198A NO895198A NO178188C NO 178188 C NO178188 C NO 178188C NO 895198 A NO895198 A NO 895198A NO 895198 A NO895198 A NO 895198A NO 178188 C NO178188 C NO 178188C
Authority
NO
Norway
Prior art keywords
group
tetrahydro
preparation
atom
therapeutically active
Prior art date
Application number
NO895198A
Other languages
English (en)
Other versions
NO895198L (no
NO178188B (no
NO895198D0 (no
Inventor
Mitsuaki Ohta
Tokuo Koide
Takeshi Suzuki
Akira Matsuhisa
Isao Yanagisawa
Keiji Miyata
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26389240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO178188(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of NO895198D0 publication Critical patent/NO895198D0/no
Publication of NO895198L publication Critical patent/NO895198L/no
Publication of NO178188B publication Critical patent/NO178188B/no
Publication of NO178188C publication Critical patent/NO178188C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Adhesive Tapes (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Reinforced Plastic Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
NO895198A 1988-12-22 1989-12-21 Analogifremgangsmåte for fremstilling av terapeutisk aktive 4,5,6,7-tetrahydro-benzimidazolderivater NO178188C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32532788 1988-12-22
JP4889689 1989-02-28

Publications (4)

Publication Number Publication Date
NO895198D0 NO895198D0 (no) 1989-12-21
NO895198L NO895198L (no) 1990-06-25
NO178188B NO178188B (no) 1995-10-30
NO178188C true NO178188C (no) 1996-02-07

Family

ID=26389240

Family Applications (1)

Application Number Title Priority Date Filing Date
NO895198A NO178188C (no) 1988-12-22 1989-12-21 Analogifremgangsmåte for fremstilling av terapeutisk aktive 4,5,6,7-tetrahydro-benzimidazolderivater

Country Status (15)

Country Link
US (1) US4977175A (no)
EP (1) EP0376624B1 (no)
KR (1) KR900009608A (no)
CN (1) CN1027536C (no)
AT (1) ATE111454T1 (no)
AU (1) AU630397B2 (no)
CA (1) CA2004911A1 (no)
DE (1) DE68918257T2 (no)
DK (1) DK653089A (no)
ES (1) ES2063831T3 (no)
FI (1) FI896075A7 (no)
IE (1) IE65639B1 (no)
NO (1) NO178188C (no)
PT (1) PT92609B (no)
YU (1) YU47216B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2095855T3 (es) * 1989-02-02 1997-03-01 Yamanouchi Pharma Co Ltd Derivados de tetrahidrobencimidazol.
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
GB9225141D0 (en) * 1992-12-01 1993-01-20 Smithkline Beecham Corp Chemical compounds
US5262537A (en) * 1993-03-19 1993-11-16 Anaquest, Inc. Derivatives of 4,5,6,7-tetrahydroimidazo-[4,5-c]pyridinyl-6-carboxylic acid
HUP9900625A3 (en) * 1995-12-28 2003-04-28 Fujisawa Pharmaceutical Co Benzimidazole derivatives, pharmaceutical compositions containing them and process for preparing the compounds
TW453999B (en) 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
AU2001244088A1 (en) * 2000-03-17 2001-09-24 Boehringer Ingelheim International G.M.B.H Condensed imidazoles as histamine h3 receptor ligands
US6437147B1 (en) 2000-03-17 2002-08-20 Novo Nordisk Imidazole compounds
AU2003237881A1 (en) 2002-05-17 2003-12-02 Neurogen Corporation Substituted ring-fused imidazole derivates: gabaa receptor ligands
WO2018033448A1 (de) * 2016-08-16 2018-02-22 Bayer Cropscience Aktiengesellschaft Verfahren zur herstellung von 2-(3,6-dihalopyridin-2-yl)-3h-imidazol[4,5-c]pyridinderivaten und verwandten verbindungen durch umsetzung des 3h-imidazol[4,5-c]pyridinderivats mit einer metallorganischen zink-amin base

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1260294A (en) * 1968-03-15 1972-01-12 Rhein Chemie Holding G M B H 4,5,6,7-tetrahydrobenzimidazoles, process for their production and their use as corrosion inhibitors and antioxidants
DE1948795A1 (de) * 1969-09-26 1971-04-08 Rhein Chemie Rheinau Gmbh 4,5,6,7-Tetrahydrobenzimidazole,Verfahren zu ihrer Herstellung und ihre Verwendung als Korrosionsinhibitoren und Alterungsschutzmittel
US3987054A (en) * 1970-09-23 1976-10-19 Pliva Pharmaceutical And Chemical Works 4,5,6,7-tetrahydrobenzimidazoles
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
SE460359B (sv) * 1984-01-25 1989-10-02 Glaxo Group Ltd 3-imidazolylmetyltetrahydrokarbazoloner, foerfarande foer framstaellning av dessa och en farmaceutisk komposition
DE3687080T2 (de) * 1985-04-27 1993-03-25 Beecham Group Plc Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung.
US4826990A (en) * 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents

Also Published As

Publication number Publication date
EP0376624A1 (en) 1990-07-04
NO895198L (no) 1990-06-25
EP0376624B1 (en) 1994-09-14
CA2004911A1 (en) 1990-06-22
DK653089D0 (da) 1989-12-21
CN1043706A (zh) 1990-07-11
AU630397B2 (en) 1992-10-29
DK653089A (da) 1990-06-23
ATE111454T1 (de) 1994-09-15
YU243989A (en) 1991-02-28
US4977175A (en) 1990-12-11
FI896075A0 (fi) 1989-12-19
IE65639B1 (en) 1995-11-15
NO178188B (no) 1995-10-30
PT92609A (pt) 1990-06-29
KR900009608A (ko) 1990-07-05
YU47216B (sh) 1995-01-31
ES2063831T3 (es) 1995-01-16
NO895198D0 (no) 1989-12-21
IE894185L (en) 1990-06-22
PT92609B (pt) 1995-09-12
DE68918257D1 (de) 1994-10-20
CN1027536C (zh) 1995-02-01
FI896075A7 (fi) 1990-06-23
AU4714589A (en) 1990-06-28
DE68918257T2 (de) 1995-02-02

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