PT92609B - Processo para a preparacao de derivados 4,5,6,7-tetrahidroben zimidazoles - Google Patents

Processo para a preparacao de derivados 4,5,6,7-tetrahidroben zimidazoles Download PDF

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Publication number
PT92609B
PT92609B PT92609A PT9260989A PT92609B PT 92609 B PT92609 B PT 92609B PT 92609 A PT92609 A PT 92609A PT 9260989 A PT9260989 A PT 9260989A PT 92609 B PT92609 B PT 92609B
Authority
PT
Portugal
Prior art keywords
group
tetrahydrobenzimidazole
added
physico
methyl
Prior art date
Application number
PT92609A
Other languages
English (en)
Portuguese (pt)
Other versions
PT92609A (pt
Inventor
Tokuo Koide
Akira Matsuhisa
Mitsuaki Ohta
Takeshi Suzuki
Keiji Miyata
Isao Yanagisawa
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26389240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT92609(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of PT92609A publication Critical patent/PT92609A/pt
Publication of PT92609B publication Critical patent/PT92609B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Reinforced Plastic Materials (AREA)
  • Adhesive Tapes (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
PT92609A 1988-12-22 1989-12-18 Processo para a preparacao de derivados 4,5,6,7-tetrahidroben zimidazoles PT92609B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP32532788 1988-12-22
JP4889689 1989-02-28

Publications (2)

Publication Number Publication Date
PT92609A PT92609A (pt) 1990-06-29
PT92609B true PT92609B (pt) 1995-09-12

Family

ID=26389240

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92609A PT92609B (pt) 1988-12-22 1989-12-18 Processo para a preparacao de derivados 4,5,6,7-tetrahidroben zimidazoles

Country Status (15)

Country Link
US (1) US4977175A (no)
EP (1) EP0376624B1 (no)
KR (1) KR900009608A (no)
CN (1) CN1027536C (no)
AT (1) ATE111454T1 (no)
AU (1) AU630397B2 (no)
CA (1) CA2004911A1 (no)
DE (1) DE68918257T2 (no)
DK (1) DK653089A (no)
ES (1) ES2063831T3 (no)
FI (1) FI896075A0 (no)
IE (1) IE65639B1 (no)
NO (1) NO178188C (no)
PT (1) PT92609B (no)
YU (1) YU47216B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU626980B2 (en) * 1989-02-02 1992-08-13 Astellas Pharma Inc. Tetrahydrobenzimidazole derivatives
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
GB9225141D0 (en) * 1992-12-01 1993-01-20 Smithkline Beecham Corp Chemical compounds
US5262537A (en) * 1993-03-19 1993-11-16 Anaquest, Inc. Derivatives of 4,5,6,7-tetrahydroimidazo-[4,5-c]pyridinyl-6-carboxylic acid
BR9612434A (pt) 1995-12-28 1999-12-28 Fujiwasa Pharmaceutical Co Ltd Derivados de benzimidazol
TW453999B (en) 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
EP1268484A1 (en) * 2000-03-17 2003-01-02 Novo Nordisk A/S Condensed imidazoles as histamine h3 receptor ligands
US6437147B1 (en) 2000-03-17 2002-08-20 Novo Nordisk Imidazole compounds
ES2273008T3 (es) * 2002-05-17 2007-05-01 Neurogen Corporation Derivados de imidazol con anillos fusionados sustituidos: ligandos de receptores gaba sba/sb.
JP7098600B2 (ja) * 2016-08-16 2022-07-11 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体を有機金属亜鉛－アミン塩基と反応させることによる２－（３，６－ジハロピリジン－２－イル）－３Ｈ－イミダゾール［４，５－ｃ］ピリジン誘導体及び関連化合物の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1260294A (en) * 1968-03-15 1972-01-12 Rhein Chemie Holding G M B H 4,5,6,7-tetrahydrobenzimidazoles, process for their production and their use as corrosion inhibitors and antioxidants
DE1948795A1 (de) * 1969-09-26 1971-04-08 Rhein Chemie Rheinau Gmbh 4,5,6,7-Tetrahydrobenzimidazole,Verfahren zu ihrer Herstellung und ihre Verwendung als Korrosionsinhibitoren und Alterungsschutzmittel
US3987054A (en) * 1970-09-23 1976-10-19 Pliva Pharmaceutical And Chemical Works 4,5,6,7-tetrahydrobenzimidazoles
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
IE57809B1 (en) * 1984-01-25 1993-04-21 Glaxo Group Ltd 1,2,3,9-tetrahydro-3-(imidazol-1-ylmethyl)-4h-carbazol-4 one derivatives
EP0200444B1 (en) * 1985-04-27 1992-11-11 Beecham Group Plc Azabicyclononyl-indazole-carboxamide having 5-ht antagonist activity
US4826990A (en) * 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents

Also Published As

Publication number Publication date
NO895198D0 (no) 1989-12-21
IE894185L (en) 1990-06-22
CA2004911A1 (en) 1990-06-22
YU243989A (en) 1991-02-28
FI896075A0 (fi) 1989-12-19
KR900009608A (ko) 1990-07-05
AU4714589A (en) 1990-06-28
PT92609A (pt) 1990-06-29
NO178188C (no) 1996-02-07
DE68918257D1 (de) 1994-10-20
IE65639B1 (en) 1995-11-15
US4977175A (en) 1990-12-11
EP0376624B1 (en) 1994-09-14
ES2063831T3 (es) 1995-01-16
EP0376624A1 (en) 1990-07-04
CN1043706A (zh) 1990-07-11
DK653089D0 (da) 1989-12-21
NO895198L (no) 1990-06-25
CN1027536C (zh) 1995-02-01
ATE111454T1 (de) 1994-09-15
NO178188B (no) 1995-10-30
DE68918257T2 (de) 1995-02-02
AU630397B2 (en) 1992-10-29
DK653089A (da) 1990-06-23
YU47216B (sh) 1995-01-31

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FG3A Patent granted, date of granting

Effective date: 19950505

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19961130