NO177266C - Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler

Info

Publication number
NO177266C
NO177266C NO911302A NO911302A NO177266C NO 177266 C NO177266 C NO 177266C NO 911302 A NO911302 A NO 911302A NO 911302 A NO911302 A NO 911302A NO 177266 C NO177266 C NO 177266C
Authority
NO
Norway
Prior art keywords
preparation
therapeutically active
analogous process
active substituted
substituted azoles
Prior art date
Application number
NO911302A
Other languages
English (en)
Other versions
NO911302D0 (no
NO177266B (no
NO911302L (no
Inventor
Adalbert Wagner
Rainer Henning
Hermann Gerhards
Bernward Scholkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO911302D0 publication Critical patent/NO911302D0/no
Publication of NO911302L publication Critical patent/NO911302L/no
Priority to NO950118A priority Critical patent/NO179705C/no
Publication of NO177266B publication Critical patent/NO177266B/no
Publication of NO177266C publication Critical patent/NO177266C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Detergent Compositions (AREA)
  • Coloring (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
NO911302A 1990-04-04 1991-04-03 Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler NO177266C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO950118A NO179705C (no) 1990-04-04 1995-01-12 Nye azolderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4010797A DE4010797A1 (de) 1990-04-04 1990-04-04 Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung

Publications (4)

Publication Number Publication Date
NO911302D0 NO911302D0 (no) 1991-04-03
NO911302L NO911302L (no) 1991-10-07
NO177266B NO177266B (no) 1995-05-08
NO177266C true NO177266C (no) 1995-08-16

Family

ID=6403704

Family Applications (1)

Application Number Title Priority Date Filing Date
NO911302A NO177266C (no) 1990-04-04 1991-04-03 Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler

Country Status (25)

Country Link
US (2) US5350751A (no)
EP (1) EP0450566B1 (no)
JP (1) JP3212036B2 (no)
KR (1) KR910018376A (no)
CN (2) CN1031940C (no)
AT (1) ATE124696T1 (no)
AU (2) AU644857B2 (no)
CA (1) CA2039622A1 (no)
CZ (1) CZ280248B6 (no)
DE (2) DE4010797A1 (no)
DK (1) DK0450566T3 (no)
ES (1) ES2076395T3 (no)
FI (1) FI911584A (no)
HU (2) HU213096B (no)
IE (1) IE67790B1 (no)
IL (1) IL97760A (no)
MA (1) MA22112A1 (no)
MX (1) MX25204A (no)
MY (1) MY109937A (no)
NO (1) NO177266C (no)
NZ (2) NZ260561A (no)
PT (1) PT97254B (no)
RU (2) RU2060255C1 (no)
SK (1) SK278797B6 (no)
ZA (1) ZA912458B (no)

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DE4010797A1 (de) * 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE4023215A1 (de) * 1990-07-21 1992-01-23 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
US5374615A (en) * 1990-10-31 1994-12-20 E. R. Squibb & Sons, Inc. Indole- and benzimidazole-substituted imidazole and benzimidazole derivatives
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DE4036706A1 (de) * 1990-11-17 1992-05-21 Hoechst Ag Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie
TW197428B (no) 1991-01-04 1993-01-01 Hoechst Ag
CA2058198A1 (en) * 1991-01-04 1992-07-05 Adalbert Wagner Azole derivatives, process for their preparation, and their use
GB9108811D0 (en) * 1991-04-24 1991-06-12 Erba Carlo Spa N-imidazolyl derivatives of substituted indole
TW215434B (no) * 1992-03-07 1993-11-01 Hoechst Ag
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DK2170930T3 (da) 2007-06-04 2012-11-05 Synergy Pharmaceuticals Inc Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
JP2013506624A (ja) * 2009-09-23 2013-02-28 アミラ ファーマシューティカルズ，インク． ５−リポキシゲナーゼのインドリジンインヒビター
US20130005721A1 (en) * 2009-09-23 2013-01-03 Panmira Pharmaceuticals, Llc Indolizine inhibitors of 5-lipoxygenase
IN2012DN04917A (no) 2009-11-05 2015-09-25 Univ Notre Dame Du Lac
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
KR102272746B1 (ko) 2013-06-05 2021-07-08 보슈 헬스 아일랜드 리미티드 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법
JP7055378B2 (ja) 2015-09-17 2022-04-18 ユニバーシティ・オブ・ノートル・ダム・デュ・ラック マイコバクテリア感染症に対して有用なベンジルアミン含有複素環化合物及び組成物
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Also Published As

Publication number Publication date
DE4010797A1 (de) 1991-10-10
EP0450566B1 (de) 1995-07-05
JPH04234876A (ja) 1992-08-24
FI911584A (fi) 1991-10-05
NO911302D0 (no) 1991-04-03
HUT60734A (en) 1992-10-28
MY109937A (en) 1997-10-31
US5350751A (en) 1994-09-27
EP0450566A1 (de) 1991-10-09
MA22112A1 (fr) 1991-12-31
AU644857B2 (en) 1993-12-23
CZ280248B6 (cs) 1995-12-13
CN1036263C (zh) 1997-10-29
US5440046A (en) 1995-08-08
PT97254A (pt) 1992-01-31
NO177266B (no) 1995-05-08
RU95108590A (ru) 1997-03-20
ATE124696T1 (de) 1995-07-15
IE67790B1 (en) 1996-04-17
AU7401391A (en) 1991-10-10
CS9100906A2 (en) 1991-11-12
IL97760A0 (en) 1992-06-21
IE911098A1 (en) 1991-10-09
CN1031940C (zh) 1996-06-05
CN1055361A (zh) 1991-10-16
MX25204A (es) 1993-08-01
HU211464A9 (en) 1995-11-28
HU911091D0 (en) 1991-10-28
NZ260561A (en) 1995-01-27
ES2076395T3 (es) 1995-11-01
AU658781B2 (en) 1995-04-27
KR910018376A (ko) 1991-11-30
DK0450566T3 (da) 1995-10-30
RU2060255C1 (ru) 1996-05-20
AU5256093A (en) 1994-02-24
JP3212036B2 (ja) 2001-09-25
DE59105897D1 (de) 1995-08-10
NZ237644A (en) 1994-12-22
SK278797B6 (sk) 1998-03-04
NO911302L (no) 1991-10-07
IL97760A (en) 1997-06-10
RU2092482C1 (ru) 1997-10-10
PT97254B (pt) 1998-07-31
ZA912458B (en) 1991-12-24
CN1105993A (zh) 1995-08-02
HU213096B (en) 1997-02-28
FI911584A0 (fi) 1991-04-02
CA2039622A1 (en) 1991-10-05

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