NO911302D0 - Fremgangsmaate for fremstilling av substituerte azoler, oganvendelse av midler som inneholder disse. - Google Patents

Fremgangsmaate for fremstilling av substituerte azoler, oganvendelse av midler som inneholder disse.

Info

Publication number
NO911302D0
NO911302D0 NO911302A NO911302A NO911302D0 NO 911302 D0 NO911302 D0 NO 911302D0 NO 911302 A NO911302 A NO 911302A NO 911302 A NO911302 A NO 911302A NO 911302 D0 NO911302 D0 NO 911302D0
Authority
NO
Norway
Prior art keywords
azols
substituted
procedure
manufacture
mentals
Prior art date
Application number
NO911302A
Other languages
English (en)
Other versions
NO911302L (no
NO177266C (no
NO177266B (no
Inventor
Adalbert Wagner
Rainer Henning
Hermann Gerhards
Bernhard Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO911302D0 publication Critical patent/NO911302D0/no
Publication of NO911302L publication Critical patent/NO911302L/no
Priority to NO950118A priority Critical patent/NO179705C/no
Publication of NO177266B publication Critical patent/NO177266B/no
Publication of NO177266C publication Critical patent/NO177266C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Coloring (AREA)
  • Pyrrole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
NO911302A 1990-04-04 1991-04-03 Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler NO177266C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO950118A NO179705C (no) 1990-04-04 1995-01-12 Nye azolderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4010797A DE4010797A1 (de) 1990-04-04 1990-04-04 Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung

Publications (4)

Publication Number Publication Date
NO911302D0 true NO911302D0 (no) 1991-04-03
NO911302L NO911302L (no) 1991-10-07
NO177266B NO177266B (no) 1995-05-08
NO177266C NO177266C (no) 1995-08-16

Family

ID=6403704

Family Applications (1)

Application Number Title Priority Date Filing Date
NO911302A NO177266C (no) 1990-04-04 1991-04-03 Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte azoler

Country Status (25)

Country Link
US (2) US5350751A (no)
EP (1) EP0450566B1 (no)
JP (1) JP3212036B2 (no)
KR (1) KR910018376A (no)
CN (2) CN1031940C (no)
AT (1) ATE124696T1 (no)
AU (2) AU644857B2 (no)
CA (1) CA2039622A1 (no)
CZ (1) CZ280248B6 (no)
DE (2) DE4010797A1 (no)
DK (1) DK0450566T3 (no)
ES (1) ES2076395T3 (no)
FI (1) FI911584A (no)
HU (2) HU213096B (no)
IE (1) IE67790B1 (no)
IL (1) IL97760A (no)
MA (1) MA22112A1 (no)
MX (1) MX25204A (no)
MY (1) MY109937A (no)
NO (1) NO177266C (no)
NZ (2) NZ260561A (no)
PT (1) PT97254B (no)
RU (2) RU2060255C1 (no)
SK (1) SK278797B6 (no)
ZA (1) ZA912458B (no)

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DE4010797A1 (de) * 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE4023215A1 (de) * 1990-07-21 1992-01-23 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
PH31175A (en) * 1990-10-31 1998-03-20 Squibb & Sons Inc Indole and benzimi-dazole-substituted imidazole and benzimidazole derivatives.
US5374615A (en) * 1990-10-31 1994-12-20 E. R. Squibb & Sons, Inc. Indole- and benzimidazole-substituted imidazole and benzimidazole derivatives
DE4036706A1 (de) * 1990-11-17 1992-05-21 Hoechst Ag Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie
CA2058198A1 (en) * 1991-01-04 1992-07-05 Adalbert Wagner Azole derivatives, process for their preparation, and their use
TW197428B (no) 1991-01-04 1993-01-01 Hoechst Ag
GB9108811D0 (en) * 1991-04-24 1991-06-12 Erba Carlo Spa N-imidazolyl derivatives of substituted indole
TW215434B (no) * 1992-03-07 1993-11-01 Hoechst Ag
US5364869A (en) * 1992-03-09 1994-11-15 Abbott Laboratories Heterocycle-substituted benzyaminopyridine angiotensin II receptor antagonists
RU2103262C1 (ru) * 1992-07-16 1998-01-27 Лонца АГ Гампель/Валлис Способ получения 2-замещенных 5-хлоримидазол-4-карбальдегидов
EP0614889A1 (de) * 1993-03-12 1994-09-14 Lonza Ag Verfahren zur Herstellung von gegebenenfalls 2-substituierten 5-Chlorimidazol-4-carbaldehyden
US5442075A (en) * 1993-03-12 1995-08-15 Lonza Ltd. Process for the production of 2-substituted 5-chlorimidazole-4-carbaldehydes
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SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
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AU2002364381A1 (en) * 2001-11-23 2003-06-10 Solvay Pharmaceuticals Gmbh Hypertonia treatment during the acute phase of a cerebrovascular accident
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CA2583087C (en) 2003-09-19 2012-07-10 Galileo Pharmaceuticals, Inc. Chroman derivatives
WO2007107470A2 (en) 2006-03-22 2007-09-27 F. Hoffmann-La Roche Ag Pyrazoles as 11-beta-hsd-1
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2009149279A2 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US20120214840A1 (en) * 2009-09-23 2012-08-23 Panmira Pharmaceuticals, Llc Indolizine inhibitors of 5-lipoxygenase
EP2480547A4 (en) * 2009-09-23 2013-02-20 Panmira Pharmaceuticals Llc INDOLIZINE INHIBITORS OF 5-LIPOXYGENASE
IN2012DN04917A (no) 2009-11-05 2015-09-25 Univ Notre Dame Du Lac
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
JP7055378B2 (ja) 2015-09-17 2022-04-18 ユニバーシティ・オブ・ノートル・ダム・デュ・ラック マイコバクテリア感染症に対して有用なベンジルアミン含有複素環化合物及び組成物
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DE4023215A1 (de) * 1990-07-21 1992-01-23 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
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Also Published As

Publication number Publication date
RU2060255C1 (ru) 1996-05-20
EP0450566A1 (de) 1991-10-09
FI911584A (fi) 1991-10-05
NO911302L (no) 1991-10-07
MX25204A (es) 1993-08-01
CN1031940C (zh) 1996-06-05
HU911091D0 (en) 1991-10-28
IE911098A1 (en) 1991-10-09
PT97254A (pt) 1992-01-31
JP3212036B2 (ja) 2001-09-25
AU644857B2 (en) 1993-12-23
IE67790B1 (en) 1996-04-17
KR910018376A (ko) 1991-11-30
NZ260561A (en) 1995-01-27
US5440046A (en) 1995-08-08
EP0450566B1 (de) 1995-07-05
ATE124696T1 (de) 1995-07-15
JPH04234876A (ja) 1992-08-24
HU213096B (en) 1997-02-28
MY109937A (en) 1997-10-31
US5350751A (en) 1994-09-27
MA22112A1 (fr) 1991-12-31
IL97760A (en) 1997-06-10
SK278797B6 (sk) 1998-03-04
ES2076395T3 (es) 1995-11-01
IL97760A0 (en) 1992-06-21
HU211464A9 (en) 1995-11-28
DE59105897D1 (de) 1995-08-10
AU658781B2 (en) 1995-04-27
CN1105993A (zh) 1995-08-02
CS9100906A2 (en) 1991-11-12
CZ280248B6 (cs) 1995-12-13
RU2092482C1 (ru) 1997-10-10
FI911584A0 (fi) 1991-04-02
RU95108590A (ru) 1997-03-20
CN1036263C (zh) 1997-10-29
HUT60734A (en) 1992-10-28
AU5256093A (en) 1994-02-24
CN1055361A (zh) 1991-10-16
CA2039622A1 (en) 1991-10-05
DK0450566T3 (da) 1995-10-30
NO177266C (no) 1995-08-16
NZ237644A (en) 1994-12-22
NO177266B (no) 1995-05-08
DE4010797A1 (de) 1991-10-10
AU7401391A (en) 1991-10-10
PT97254B (pt) 1998-07-31
ZA912458B (en) 1991-12-24

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