NO176565C - Analogifremgangsmåte for fremstilling av antitrombotisk aktive forbindelser - Google Patents

Analogifremgangsmåte for fremstilling av antitrombotisk aktive forbindelser

Info

Publication number
NO176565C
NO176565C NO905511A NO905511A NO176565C NO 176565 C NO176565 C NO 176565C NO 905511 A NO905511 A NO 905511A NO 905511 A NO905511 A NO 905511A NO 176565 C NO176565 C NO 176565C
Authority
NO
Norway
Prior art keywords
preparation
active compounds
analogous process
antithrombotically
antithrombotically active
Prior art date
Application number
NO905511A
Other languages
English (en)
Norwegian (no)
Other versions
NO905511D0 (no
NO905511L (no
NO176565B (no
Inventor
Albert Anthony Carr
Richard Cyrus Dage
John Ednar Koerner
Tung Li
Francis Peter Miller
Thaddeus Robert Nieduzak
Mark William Dudley
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO905511D0 publication Critical patent/NO905511D0/no
Publication of NO905511L publication Critical patent/NO905511L/no
Publication of NO176565B publication Critical patent/NO176565B/no
Publication of NO176565C publication Critical patent/NO176565C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO905511A 1989-12-21 1990-12-20 Analogifremgangsmåte for fremstilling av antitrombotisk aktive forbindelser NO176565C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45449789A 1989-12-21 1989-12-21
US60465190A 1990-11-01 1990-11-01

Publications (4)

Publication Number Publication Date
NO905511D0 NO905511D0 (no) 1990-12-20
NO905511L NO905511L (no) 1991-06-24
NO176565B NO176565B (no) 1995-01-16
NO176565C true NO176565C (no) 1995-04-26

Family

ID=27037488

Family Applications (1)

Application Number Title Priority Date Filing Date
NO905511A NO176565C (no) 1989-12-21 1990-12-20 Analogifremgangsmåte for fremstilling av antitrombotisk aktive forbindelser

Country Status (20)

Country Link
EP (1) EP0437790B1 (de)
JP (1) JP2934323B2 (de)
KR (1) KR0184641B1 (de)
CN (1) CN1025853C (de)
AR (1) AR247200A1 (de)
AT (1) ATE133163T1 (de)
AU (1) AU635098B2 (de)
CA (1) CA2032797C (de)
DE (1) DE69024933T2 (de)
DK (1) DK0437790T3 (de)
ES (1) ES2084642T3 (de)
FI (1) FI96946C (de)
GR (1) GR3018895T3 (de)
HU (1) HU210590B (de)
IE (1) IE71039B1 (de)
IL (1) IL96731A (de)
NO (1) NO176565C (de)
NZ (1) NZ236501A (de)
PT (1) PT96291B (de)
TW (1) TW199145B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292752A (en) * 1989-12-21 1994-03-08 Merrell Dow Pharmaceuticals Inc. Antithrombotic compounds
US5478846A (en) * 1990-06-07 1995-12-26 Merrell Dow Pharmaceuticals Inc. 1-piperidinyl alkanoylanyl sulfonamides for treatment of cardiac arrhythmia
EP0532629B1 (de) * 1990-06-07 1996-11-06 Merrell Pharmaceuticals Inc. Derivate des 1-piperidinyl-alkanoylarylsulfonamids
EP0661266A1 (de) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituierte cyclische Aminverbindungen als 5HT2 Antagonisten
JP3274579B2 (ja) * 1995-01-12 2002-04-15 住友製薬株式会社 脳血管障害に伴う精神症候治療剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4355037A (en) * 1981-11-12 1982-10-19 Hoechst-Roussel Pharmaceuticals 3-(4-Piperidyl)-1,2-benzisoxales
FR2581993B1 (fr) * 1985-05-14 1988-03-18 Synthelabo Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
WO1988004918A1 (en) * 1987-01-12 1988-07-14 Ricchio Dominic A Method and apparatus for improved water therapy
US5093341A (en) * 1987-12-17 1992-03-03 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine derivatives useful as antithrombolytic agents
US5064838A (en) * 1988-01-21 1991-11-12 Merrell Dow Pharmaceuticals 1,4-disubstituted-piperidinyl compounds as pain relievers
JP2969359B2 (ja) * 1989-01-13 1999-11-02 武田薬品工業株式会社 環状アミン化合物

Also Published As

Publication number Publication date
FI96946C (fi) 1996-09-25
CA2032797C (en) 2002-03-19
IE71039B1 (en) 1997-01-15
AR247200A1 (es) 1994-11-30
DE69024933T2 (de) 1996-05-30
DE69024933D1 (de) 1996-02-29
CA2032797A1 (en) 1991-06-22
PT96291B (pt) 1998-06-30
NO905511D0 (no) 1990-12-20
FI906246A0 (fi) 1990-12-18
IE904632A1 (en) 1991-07-17
KR0184641B1 (ko) 1999-05-01
PT96291A (pt) 1991-09-30
ATE133163T1 (de) 1996-02-15
HU210590B (en) 1995-05-29
EP0437790A3 (en) 1992-04-08
GR3018895T3 (en) 1996-05-31
CN1052664A (zh) 1991-07-03
AU6818190A (en) 1991-06-27
DK0437790T3 (da) 1996-02-12
ES2084642T3 (es) 1996-05-16
JPH04145068A (ja) 1992-05-19
IL96731A (en) 1995-06-29
FI906246A (fi) 1991-06-22
KR910011787A (ko) 1991-08-07
TW199145B (de) 1993-02-01
CN1025853C (zh) 1994-09-07
EP0437790B1 (de) 1996-01-17
JP2934323B2 (ja) 1999-08-16
FI96946B (fi) 1996-06-14
AU635098B2 (en) 1993-03-11
HU908370D0 (en) 1991-07-29
NO905511L (no) 1991-06-24
EP0437790A2 (de) 1991-07-24
NO176565B (no) 1995-01-16
NZ236501A (en) 1992-12-23

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Free format text: LAPSED IN JUNE 2001