NO174517B - Fremgangsmaate for fremstilling av et nytt antibiotikum, Mersacidin - Google Patents
Fremgangsmaate for fremstilling av et nytt antibiotikum, Mersacidin Download PDFInfo
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- NO174517B NO174517B NO893288A NO893288A NO174517B NO 174517 B NO174517 B NO 174517B NO 893288 A NO893288 A NO 893288A NO 893288 A NO893288 A NO 893288A NO 174517 B NO174517 B NO 174517B
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- Prior art keywords
- mersacidin
- compound
- culture
- formula
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- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3827868A DE3827868A1 (de) | 1988-08-17 | 1988-08-17 | Ein neues antibiotikum, mersacidin, ein verfahren zu seiner herstellung und seine verwendung als arzneimittel |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO893288D0 NO893288D0 (no) | 1989-08-16 |
| NO893288L NO893288L (no) | 1990-02-19 |
| NO174517B true NO174517B (no) | 1994-02-07 |
| NO174517C NO174517C (xx) | 1994-05-18 |
Family
ID=6361001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO893288A NO174517B (no) | 1988-08-17 | 1989-08-16 | Fremgangsmaate for fremstilling av et nytt antibiotikum, Mersacidin |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5112806A (xx) |
| EP (1) | EP0362520B1 (xx) |
| JP (1) | JP2892699B2 (xx) |
| KR (1) | KR0139628B1 (xx) |
| AT (1) | ATE113296T1 (xx) |
| AU (1) | AU613228B2 (xx) |
| CA (1) | CA1338171C (xx) |
| DE (2) | DE3827868A1 (xx) |
| DK (1) | DK175121B1 (xx) |
| ES (1) | ES2064398T3 (xx) |
| FI (1) | FI94648C (xx) |
| HU (1) | HU203906B (xx) |
| IE (1) | IE64706B1 (xx) |
| IL (1) | IL91317A0 (xx) |
| IN (1) | IN167138B (xx) |
| NO (1) | NO174517B (xx) |
| NZ (1) | NZ230303A (xx) |
| PH (1) | PH27179A (xx) |
| PT (1) | PT91468B (xx) |
| ZA (1) | ZA896245B (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0700998B1 (en) * | 1994-09-12 | 2003-11-26 | Aventis Pharma Deutschland GmbH | Recombinant mersacidin and a method for production |
| US5910479A (en) * | 1996-10-18 | 1999-06-08 | Ambi Inc. | Method for the treatment of Streptococcus pneumoniae infection |
| US6861236B2 (en) * | 2002-05-24 | 2005-03-01 | Applied Nanosystems B.V. | Export and modification of (poly)peptides in the lantibiotic way |
| GB0406870D0 (en) | 2004-03-26 | 2004-04-28 | Novacta Biosystems Ltd | Improvements relating to the production of lantibiotics |
| EP1928900A1 (en) * | 2005-09-27 | 2008-06-11 | Novacta Biosystems Limited | Variants of the lantibiotic mersacidin and their use |
| GB0600928D0 (en) | 2006-01-17 | 2006-02-22 | Novacta Biosystems Ltd | Improvements relating to lantibiotics |
| GB0714029D0 (en) * | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | Lantibiotic-based compounds having antimicrobial activity |
| GB0714030D0 (en) * | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
| EA021683B1 (ru) | 2009-01-14 | 2015-08-31 | Новакта Биосистемс Лимитед | Производные деоксиактагардина в |
| NZ594675A (en) | 2009-02-04 | 2013-11-29 | Novacta Biosystems Ltd | Actagardine derivatives |
| GB201001688D0 (en) | 2010-02-02 | 2010-03-17 | Novacta Biosystems Ltd | Compounds |
| GB201013513D0 (en) | 2010-08-11 | 2010-09-22 | Novacta Biosystems Ltd | Formulations |
| KR102582570B1 (ko) * | 2021-03-19 | 2023-09-22 | 한국생명공학연구원 | 유박테리움 칼란데리, 이의 배양액 또는 이의 배양액 추출물을 유효성분으로 포함하는 암 예방 또는 치료용 조성물 |
| WO2023049300A1 (en) * | 2021-09-22 | 2023-03-30 | Biomedit, Llc | Methods of inhibiting diseases caused by respiratory viruses |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4493796A (en) * | 1980-09-12 | 1985-01-15 | Board Of Trustees, Univ. Of Ill. | Didemnins A, B, C, and derivatives thereof, as antiviral agents |
| JPS61134398A (ja) * | 1984-12-06 | 1986-06-21 | Microbial Chem Res Found | 新生理活性物質プリパスタチン及びその製造法 |
-
1988
- 1988-07-04 IN IN193/BOM/88A patent/IN167138B/en unknown
- 1988-08-17 DE DE3827868A patent/DE3827868A1/de not_active Withdrawn
-
1989
- 1989-08-14 DE DE58908558T patent/DE58908558D1/de not_active Expired - Lifetime
- 1989-08-14 AT AT89114990T patent/ATE113296T1/de not_active IP Right Cessation
- 1989-08-14 EP EP89114990A patent/EP0362520B1/de not_active Expired - Lifetime
- 1989-08-14 ES ES89114990T patent/ES2064398T3/es not_active Expired - Lifetime
- 1989-08-15 NZ NZ230303A patent/NZ230303A/en unknown
- 1989-08-15 FI FI893842A patent/FI94648C/fi active IP Right Grant
- 1989-08-15 PH PH39098A patent/PH27179A/en unknown
- 1989-08-15 US US07/393,953 patent/US5112806A/en not_active Expired - Lifetime
- 1989-08-15 IL IL91317A patent/IL91317A0/xx unknown
- 1989-08-16 AU AU39966/89A patent/AU613228B2/en not_active Expired
- 1989-08-16 JP JP1210228A patent/JP2892699B2/ja not_active Expired - Lifetime
- 1989-08-16 CA CA000608500A patent/CA1338171C/en not_active Expired - Lifetime
- 1989-08-16 IE IE263889A patent/IE64706B1/en not_active IP Right Cessation
- 1989-08-16 DK DK198904037A patent/DK175121B1/da not_active IP Right Cessation
- 1989-08-16 HU HU894215A patent/HU203906B/hu unknown
- 1989-08-16 ZA ZA896245A patent/ZA896245B/xx unknown
- 1989-08-16 NO NO893288A patent/NO174517B/no not_active IP Right Cessation
- 1989-08-17 PT PT91468A patent/PT91468B/pt not_active IP Right Cessation
- 1989-08-17 KR KR1019890011679A patent/KR0139628B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PH27179A (en) | 1993-04-02 |
| DE58908558D1 (de) | 1994-12-01 |
| IL91317A0 (en) | 1990-03-19 |
| IE892638L (en) | 1990-02-17 |
| JP2892699B2 (ja) | 1999-05-17 |
| NO174517C (xx) | 1994-05-18 |
| DK175121B1 (da) | 2004-06-07 |
| NO893288D0 (no) | 1989-08-16 |
| US5112806A (en) | 1992-05-12 |
| DK403789D0 (da) | 1989-08-16 |
| IE64706B1 (en) | 1995-08-23 |
| FI893842A0 (fi) | 1989-08-15 |
| ATE113296T1 (de) | 1994-11-15 |
| PT91468B (pt) | 1995-05-04 |
| KR900003206A (ko) | 1990-03-26 |
| EP0362520A3 (de) | 1991-10-23 |
| IN167138B (xx) | 1990-09-01 |
| DE3827868A1 (de) | 1990-02-22 |
| FI94648C (fi) | 1995-10-10 |
| HUT55054A (en) | 1991-04-29 |
| CA1338171C (en) | 1996-03-19 |
| FI94648B (fi) | 1995-06-30 |
| ES2064398T3 (es) | 1995-02-01 |
| NZ230303A (en) | 1992-06-25 |
| PT91468A (pt) | 1990-03-08 |
| JPH02142800A (ja) | 1990-05-31 |
| AU3996689A (en) | 1990-02-22 |
| AU613228B2 (en) | 1991-07-25 |
| KR0139628B1 (ko) | 1998-07-01 |
| EP0362520B1 (de) | 1994-10-26 |
| ZA896245B (en) | 1990-04-25 |
| EP0362520A2 (de) | 1990-04-11 |
| NO893288L (no) | 1990-02-19 |
| HU203906B (en) | 1991-10-28 |
| DK403789A (da) | 1990-02-18 |
| FI893842A (fi) | 1990-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |