NO172849C - Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazol- og oksazol-derivater - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazol- og oksazol-derivaterInfo
- Publication number
- NO172849C NO172849C NO871028A NO871028A NO172849C NO 172849 C NO172849 C NO 172849C NO 871028 A NO871028 A NO 871028A NO 871028 A NO871028 A NO 871028A NO 172849 C NO172849 C NO 172849C
- Authority
- NO
- Norway
- Prior art keywords
- oksazol
- tiazol
- derivatives
- preparation
- therapeutically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863608290 DE3608290A1 (de) | 1986-03-13 | 1986-03-13 | Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE19863621775 DE3621775A1 (de) | 1986-03-13 | 1986-06-28 | Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO871028D0 NO871028D0 (no) | 1987-03-12 |
| NO871028L NO871028L (no) | 1987-09-14 |
| NO172849B NO172849B (no) | 1993-06-07 |
| NO172849C true NO172849C (no) | 1993-09-15 |
Family
ID=25841907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO871028A NO172849C (no) | 1986-03-13 | 1987-03-12 | Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazol- og oksazol-derivater |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US5457205A (da) |
| EP (1) | EP0239815B1 (da) |
| JP (1) | JPH0784446B2 (da) |
| KR (1) | KR870008876A (da) |
| CA (1) | CA1296002C (da) |
| DE (2) | DE3621775A1 (da) |
| DK (1) | DK168991B1 (da) |
| ES (1) | ES2040215T3 (da) |
| FI (1) | FI87777C (da) |
| GR (1) | GR3002839T3 (da) |
| HK (1) | HK106494A (da) |
| HU (1) | HU196974B (da) |
| IE (1) | IE59800B1 (da) |
| IL (1) | IL81874A (da) |
| MX (1) | MX9202818A (da) |
| NO (1) | NO172849C (da) |
| PH (1) | PH23996A (da) |
| PL (1) | PL154772B1 (da) |
| PT (1) | PT84462B (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3805382A1 (de) * | 1988-02-20 | 1989-08-31 | Boehringer Ingelheim Vetmed | Verwendung von thiazolen zur leistungssteigerung bei tieren |
| JP3003148B2 (ja) * | 1989-01-05 | 2000-01-24 | 藤沢薬品工業株式会社 | チアゾール化合物、その製造法およびそれを含有する医薬組成物 |
| HUT70422A (en) * | 1991-07-22 | 1995-10-30 | Pfizer | Chiral thiazole derivatives and process for preparing them |
| WO1995002586A1 (fr) * | 1993-07-14 | 1995-01-26 | Taisho Pharmaceutical Co., Ltd. | Derive de 5-acetylthiazoline oxime |
| US6472387B1 (en) | 1996-10-07 | 2002-10-29 | Eli Lilly And Company | Methods of using compounds as neuro-protective agents |
| US6156748A (en) | 1996-10-07 | 2000-12-05 | Eli Lilly And Company | Compounds useful as neuro-protective agents |
| DE69738809D1 (de) * | 1996-11-08 | 2008-08-14 | Nippon Chemiphar Co | Mittel zur verringerung der eigeweidefette |
| TR200001750T2 (tr) | 1997-10-06 | 2001-01-22 | Eli Lilly And Company | Nöro-koruyucu maddeler olarak yararlı yeni bileşikler. |
| US5972099A (en) * | 1997-12-17 | 1999-10-26 | Bayer Corporation | Process for preparing organic pigment compositions |
| US6121300A (en) * | 1998-11-10 | 2000-09-19 | Wagle; Dilip R. | Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts |
| EP1353918B1 (en) * | 2000-11-28 | 2005-01-12 | Smithkline Beecham Plc | Morpholine derivatives as antagonists of orexin receptors |
| CN101912380A (zh) * | 2003-04-15 | 2010-12-15 | 维尔斯达医疗公司 | 用于治疗代谢紊乱的化合物 |
| EP1618086B1 (en) | 2003-04-22 | 2009-12-02 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| GB0324654D0 (en) * | 2003-10-22 | 2003-11-26 | Glaxo Group Ltd | Medicinal compounds |
| TW200526588A (en) * | 2003-11-17 | 2005-08-16 | Smithkline Beecham Corp | Chemical compounds |
| JP6063948B2 (ja) * | 2011-10-27 | 2017-01-18 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | ベータ３アゴニストおよび中間体を製造するプロセス |
| US10791890B2 (en) | 2018-03-27 | 2020-10-06 | Omachron Intellectual Property Inc. | Surface cleaning apparatus |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3225042A (en) * | 1962-07-31 | 1965-12-21 | Lilly Co Eli | Hydroxymorpholines |
| US3514465A (en) * | 1966-12-30 | 1970-05-26 | Degussa | Certain thiazolyl- and pyridinylaminoketones |
| LU69079A1 (da) * | 1973-12-27 | 1975-08-20 | ||
| FI791727A (fi) * | 1978-06-05 | 1979-12-06 | Ciba Geigy Ag | Foerfarande foer framstaellning av n-alkylerade aminoalkoholer |
| IE50355B1 (en) * | 1979-10-20 | 1986-04-02 | Wyeth John & Brother Ltd | Morpholine derivatives |
| GB8418657D0 (en) * | 1984-07-21 | 1984-08-22 | Beecham Group Plc | Compounds |
| US4826990A (en) * | 1987-09-30 | 1989-05-02 | American Home Products Corporation | 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents |
-
1986
- 1986-06-28 DE DE19863621775 patent/DE3621775A1/de not_active Ceased
-
1987
- 1987-03-03 DE DE8787102995T patent/DE3771541D1/de not_active Expired - Fee Related
- 1987-03-03 EP EP87102995A patent/EP0239815B1/de not_active Expired - Lifetime
- 1987-03-03 ES ES198787102995T patent/ES2040215T3/es not_active Expired - Lifetime
- 1987-03-10 PL PL1987264545A patent/PL154772B1/pl unknown
- 1987-03-11 CA CA000531681A patent/CA1296002C/en not_active Expired - Lifetime
- 1987-03-11 FI FI871052A patent/FI87777C/fi not_active IP Right Cessation
- 1987-03-12 IE IE64487A patent/IE59800B1/en not_active IP Right Cessation
- 1987-03-12 DK DK127487A patent/DK168991B1/da active
- 1987-03-12 HU HU871084A patent/HU196974B/hu not_active IP Right Cessation
- 1987-03-12 JP JP62055477A patent/JPH0784446B2/ja not_active Expired - Lifetime
- 1987-03-12 NO NO871028A patent/NO172849C/no unknown
- 1987-03-12 PT PT84462A patent/PT84462B/pt not_active IP Right Cessation
- 1987-03-12 IL IL81874A patent/IL81874A/xx not_active IP Right Cessation
- 1987-03-13 PH PH35027A patent/PH23996A/en unknown
- 1987-03-13 KR KR870002258A patent/KR870008876A/ko not_active Application Discontinuation
-
1991
- 1991-10-03 GR GR91401473T patent/GR3002839T3/el unknown
-
1992
- 1992-06-12 MX MX9202818A patent/MX9202818A/es unknown
-
1993
- 1993-03-12 US US08/030,744 patent/US5457205A/en not_active Expired - Fee Related
-
1994
- 1994-10-06 HK HK106494A patent/HK106494A/xx not_active IP Right Cessation
-
1995
- 1995-05-24 US US08/449,174 patent/US5604225A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5604225A (en) | 1997-02-18 |
| ES2040215T3 (es) | 1993-10-16 |
| NO172849B (no) | 1993-06-07 |
| FI871052A0 (fi) | 1987-03-11 |
| IE870644L (en) | 1987-09-13 |
| NO871028D0 (no) | 1987-03-12 |
| DK127487D0 (da) | 1987-03-12 |
| PL264545A1 (en) | 1988-07-21 |
| JPH0784446B2 (ja) | 1995-09-13 |
| FI87777C (fi) | 1993-02-25 |
| GR3002839T3 (en) | 1993-01-25 |
| MX9202818A (es) | 1992-06-30 |
| FI87777B (fi) | 1992-11-13 |
| PT84462A (de) | 1987-04-01 |
| DK168991B1 (da) | 1994-07-25 |
| PL154772B1 (en) | 1991-09-30 |
| CA1296002C (en) | 1992-02-18 |
| KR870008876A (ko) | 1987-10-21 |
| NO871028L (no) | 1987-09-14 |
| IE59800B1 (en) | 1994-04-06 |
| JPS62226971A (ja) | 1987-10-05 |
| HU196974B (en) | 1989-02-28 |
| DE3621775A1 (de) | 1988-01-07 |
| EP0239815B1 (de) | 1991-07-24 |
| EP0239815A1 (de) | 1987-10-07 |
| HK106494A (en) | 1994-10-14 |
| DK127487A (da) | 1987-09-14 |
| HUT44246A (en) | 1988-02-29 |
| PH23996A (en) | 1990-02-09 |
| US5457205A (en) | 1995-10-10 |
| PT84462B (pt) | 1989-10-04 |
| IL81874A0 (en) | 1987-10-20 |
| DE3771541D1 (de) | 1991-08-29 |
| FI871052A (fi) | 1987-09-14 |
| IL81874A (en) | 1991-01-31 |
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