FI871052A - Nya substituerade tiazoler och oxazoler, dessa foereningar innehaollande laekemedel och foerfarande foer deras framstaellning. - Google Patents
Nya substituerade tiazoler och oxazoler, dessa foereningar innehaollande laekemedel och foerfarande foer deras framstaellning. Download PDFInfo
- Publication number
- FI871052A FI871052A FI871052A FI871052A FI871052A FI 871052 A FI871052 A FI 871052A FI 871052 A FI871052 A FI 871052A FI 871052 A FI871052 A FI 871052A FI 871052 A FI871052 A FI 871052A
- Authority
- FI
- Finland
- Prior art keywords
- och
- tiazoler
- oxazoler
- substituerade
- nya
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3608290 | 1986-03-13 | ||
| DE19863608290 DE3608290A1 (de) | 1986-03-13 | 1986-03-13 | Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE3621775 | 1986-06-28 | ||
| DE19863621775 DE3621775A1 (de) | 1986-03-13 | 1986-06-28 | Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI871052A0 FI871052A0 (fi) | 1987-03-11 |
| FI871052A true FI871052A (fi) | 1987-09-14 |
| FI87777B FI87777B (fi) | 1992-11-13 |
| FI87777C FI87777C (fi) | 1993-02-25 |
Family
ID=25841907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI871052A FI87777C (fi) | 1986-03-13 | 1987-03-11 | Foerfarande foer framstaellning av terapeutiskt anvaendbara substituerade tiazoler och oxazoler |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US5457205A (fi) |
| EP (1) | EP0239815B1 (fi) |
| JP (1) | JPH0784446B2 (fi) |
| KR (1) | KR870008876A (fi) |
| CA (1) | CA1296002C (fi) |
| DE (2) | DE3621775A1 (fi) |
| DK (1) | DK168991B1 (fi) |
| ES (1) | ES2040215T3 (fi) |
| FI (1) | FI87777C (fi) |
| GR (1) | GR3002839T3 (fi) |
| HK (1) | HK106494A (fi) |
| HU (1) | HU196974B (fi) |
| IE (1) | IE59800B1 (fi) |
| IL (1) | IL81874A (fi) |
| MX (1) | MX9202818A (fi) |
| NO (1) | NO172849C (fi) |
| PH (1) | PH23996A (fi) |
| PL (1) | PL154772B1 (fi) |
| PT (1) | PT84462B (fi) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3805382A1 (de) * | 1988-02-20 | 1989-08-31 | Boehringer Ingelheim Vetmed | Verwendung von thiazolen zur leistungssteigerung bei tieren |
| JP3003148B2 (ja) * | 1989-01-05 | 2000-01-24 | 藤沢薬品工業株式会社 | チアゾール化合物、その製造法およびそれを含有する医薬組成物 |
| CA2111446C (en) * | 1991-07-22 | 1997-12-16 | George J. Quallich | Chiral intermediates for the preparation of antidiabetics thiazoles |
| AU7084294A (en) * | 1993-07-14 | 1995-02-13 | Taisho Pharmaceutical Co., Ltd. | 5-acetylthiazoline oxime derivative |
| PT971709E (pt) * | 1996-10-07 | 2003-09-30 | Lilly Co Eli | Novos compostos uteis como agentes neuro-protectores |
| US6472387B1 (en) | 1996-10-07 | 2002-10-29 | Eli Lilly And Company | Methods of using compounds as neuro-protective agents |
| ATE399545T1 (de) * | 1996-11-08 | 2008-07-15 | Nippon Chemiphar Co | Mittel zur verringerung der eigeweidefette |
| PL339673A1 (en) | 1997-10-06 | 2001-01-02 | Lilly Co Eli | Novel compounds suitable for use as neuroprotective agents |
| US5972099A (en) * | 1997-12-17 | 1999-10-26 | Bayer Corporation | Process for preparing organic pigment compositions |
| US6121300A (en) | 1998-11-10 | 2000-09-19 | Wagle; Dilip R. | Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts |
| ATE286897T1 (de) * | 2000-11-28 | 2005-01-15 | Smithkline Beecham Plc | Morpholinderivate als antagonisten an orexinrezeptoren |
| WO2004091486A2 (en) * | 2003-04-15 | 2004-10-28 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| WO2004093806A2 (en) | 2003-04-22 | 2004-11-04 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| GB0324654D0 (en) * | 2003-10-22 | 2003-11-26 | Glaxo Group Ltd | Medicinal compounds |
| TW200526588A (en) * | 2003-11-17 | 2005-08-16 | Smithkline Beecham Corp | Chemical compounds |
| WO2013062881A1 (en) * | 2011-10-27 | 2013-05-02 | Merck Sharp & Dohme Corp. | Process for making beta 3 agonists and intermediates |
| US10791890B2 (en) | 2018-03-27 | 2020-10-06 | Omachron Intellectual Property Inc. | Surface cleaning apparatus |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3225042A (en) * | 1962-07-31 | 1965-12-21 | Lilly Co Eli | Hydroxymorpholines |
| US3514465A (en) * | 1966-12-30 | 1970-05-26 | Degussa | Certain thiazolyl- and pyridinylaminoketones |
| LU69079A1 (fi) * | 1973-12-27 | 1975-08-20 | ||
| FI791727A (fi) * | 1978-06-05 | 1979-12-06 | Ciba Geigy Ag | Foerfarande foer framstaellning av n-alkylerade aminoalkoholer |
| IE50355B1 (en) * | 1979-10-20 | 1986-04-02 | Wyeth John & Brother Ltd | Morpholine derivatives |
| GB8418657D0 (en) * | 1984-07-21 | 1984-08-22 | Beecham Group Plc | Compounds |
| US4826990A (en) * | 1987-09-30 | 1989-05-02 | American Home Products Corporation | 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents |
-
1986
- 1986-06-28 DE DE19863621775 patent/DE3621775A1/de not_active Ceased
-
1987
- 1987-03-03 ES ES198787102995T patent/ES2040215T3/es not_active Expired - Lifetime
- 1987-03-03 EP EP87102995A patent/EP0239815B1/de not_active Expired - Lifetime
- 1987-03-03 DE DE8787102995T patent/DE3771541D1/de not_active Expired - Fee Related
- 1987-03-10 PL PL1987264545A patent/PL154772B1/pl unknown
- 1987-03-11 CA CA000531681A patent/CA1296002C/en not_active Expired - Lifetime
- 1987-03-11 FI FI871052A patent/FI87777C/fi not_active IP Right Cessation
- 1987-03-12 IE IE64487A patent/IE59800B1/en not_active IP Right Cessation
- 1987-03-12 IL IL81874A patent/IL81874A/xx not_active IP Right Cessation
- 1987-03-12 HU HU871084A patent/HU196974B/hu not_active IP Right Cessation
- 1987-03-12 DK DK127487A patent/DK168991B1/da active
- 1987-03-12 NO NO871028A patent/NO172849C/no unknown
- 1987-03-12 PT PT84462A patent/PT84462B/pt not_active IP Right Cessation
- 1987-03-12 JP JP62055477A patent/JPH0784446B2/ja not_active Expired - Lifetime
- 1987-03-13 KR KR870002258A patent/KR870008876A/ko not_active Application Discontinuation
- 1987-03-13 PH PH35027A patent/PH23996A/en unknown
-
1991
- 1991-10-03 GR GR91401473T patent/GR3002839T3/el unknown
-
1992
- 1992-06-12 MX MX9202818A patent/MX9202818A/es unknown
-
1993
- 1993-03-12 US US08/030,744 patent/US5457205A/en not_active Expired - Fee Related
-
1994
- 1994-10-06 HK HK106494A patent/HK106494A/xx not_active IP Right Cessation
-
1995
- 1995-05-24 US US08/449,174 patent/US5604225A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| PT84462A (de) | 1987-04-01 |
| PL154772B1 (en) | 1991-09-30 |
| DE3621775A1 (de) | 1988-01-07 |
| IL81874A (en) | 1991-01-31 |
| US5604225A (en) | 1997-02-18 |
| PH23996A (en) | 1990-02-09 |
| PL264545A1 (en) | 1988-07-21 |
| EP0239815A1 (de) | 1987-10-07 |
| US5457205A (en) | 1995-10-10 |
| IE59800B1 (en) | 1994-04-06 |
| ES2040215T3 (es) | 1993-10-16 |
| FI87777B (fi) | 1992-11-13 |
| IE870644L (en) | 1987-09-13 |
| NO871028D0 (no) | 1987-03-12 |
| JPH0784446B2 (ja) | 1995-09-13 |
| CA1296002C (en) | 1992-02-18 |
| HU196974B (en) | 1989-02-28 |
| PT84462B (pt) | 1989-10-04 |
| HK106494A (en) | 1994-10-14 |
| JPS62226971A (ja) | 1987-10-05 |
| DK127487D0 (da) | 1987-03-12 |
| MX9202818A (es) | 1992-06-30 |
| NO172849B (no) | 1993-06-07 |
| FI87777C (fi) | 1993-02-25 |
| DE3771541D1 (de) | 1991-08-29 |
| EP0239815B1 (de) | 1991-07-24 |
| IL81874A0 (en) | 1987-10-20 |
| HUT44246A (en) | 1988-02-29 |
| KR870008876A (ko) | 1987-10-21 |
| NO871028L (no) | 1987-09-14 |
| GR3002839T3 (en) | 1993-01-25 |
| DK168991B1 (da) | 1994-07-25 |
| DK127487A (da) | 1987-09-14 |
| NO172849C (no) | 1993-09-15 |
| FI871052A0 (fi) | 1987-03-11 |
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Owner name: DR. KARL THOMAE GESELLSCHAFT MIT |