NO161373C - Analogifremgangsmaate for fremstilling av terapeutisk aktive pteridin-derivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive pteridin-derivater.

Info

Publication number
NO161373C
NO161373C NO854965A NO854965A NO161373C NO 161373 C NO161373 C NO 161373C NO 854965 A NO854965 A NO 854965A NO 854965 A NO854965 A NO 854965A NO 161373 C NO161373 C NO 161373C
Authority
NO
Norway
Prior art keywords
preparation
therapeutic active
pteridine derivatives
analogue procedure
active pteridine
Prior art date
Application number
NO854965A
Other languages
English (en)
Norwegian (no)
Other versions
NO161373B (no
NO854965L (no
Inventor
Josef Roch
Armin Heckel
Josef Nickl
Erich Mueller
Berthold Narr
Rainer Zimmermann
Hans Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO854965L publication Critical patent/NO854965L/no
Publication of NO161373B publication Critical patent/NO161373B/no
Publication of NO161373C publication Critical patent/NO161373C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/06Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO854965A 1984-12-12 1985-12-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive pteridin-derivater. NO161373C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445298 DE3445298A1 (de) 1984-12-12 1984-12-12 Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel

Publications (3)

Publication Number Publication Date
NO854965L NO854965L (no) 1986-06-13
NO161373B NO161373B (no) 1989-05-02
NO161373C true NO161373C (no) 1989-08-09

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
NO854965A NO161373C (no) 1984-12-12 1985-12-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive pteridin-derivater.

Country Status (15)

Country Link
EP (1) EP0185259A3 (OSRAM)
JP (1) JPS61140585A (OSRAM)
AU (1) AU576924B2 (OSRAM)
CA (1) CA1252783A (OSRAM)
DE (1) DE3445298A1 (OSRAM)
DK (1) DK161327C (OSRAM)
ES (1) ES8707238A1 (OSRAM)
FI (1) FI82696C (OSRAM)
GR (1) GR852996B (OSRAM)
IL (1) IL77294A (OSRAM)
NO (1) NO161373C (OSRAM)
NZ (1) NZ214522A (OSRAM)
PH (1) PH24451A (OSRAM)
PT (1) PT81650B (OSRAM)
ZA (1) ZA859462B (OSRAM)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005021003A2 (en) * 2003-08-29 2005-03-10 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
YU102503A (sh) 2001-06-28 2006-08-17 Pliva D.D. Kondenzovani pirimidinski dhfr inhibitori kao antibakterijska sredstva
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
PT1673092E (pt) * 2003-10-17 2007-11-23 4 Aza Ip Nv ''derivados de pteridina substituídos com heterociclos e sua utilização em terapia''
JP2007526323A (ja) * 2004-03-04 2007-09-13 ニューロジェン・コーポレーション アリールアルキルアミノ置換キナゾリン類縁体
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de) * 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057645A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
RU2445315C2 (ru) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед ПРОИЗВОДНЫЕ ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR
EP1954699B1 (en) * 2005-11-22 2012-09-19 Kudos Pharmaceuticals Ltd PYRIDO-, PYRAZO- AND PYRIMIDOPYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
CA2652840C (en) 2006-05-24 2014-09-09 Boehringer Ingelheim International Gmbh 2-piperazino-6-chloro-pteridines as pde4-inhibitors for the treatment of inflammatory diseases
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
US9259426B2 (en) 2006-07-20 2016-02-16 Gilead Sciences, Inc. 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
KR101438245B1 (ko) 2006-08-23 2014-09-04 쿠도스 파마슈티칼스 리미티드 Mtor 억제제로서의 2-메틸모르폴린 피리도-, 피라조- 및 피리미도-피리미딘 유도체
EP2303875B1 (en) 2008-06-20 2012-11-28 AstraZeneca AB Compositions with and process for methylmorpholin-subsituted pyrido[2,3-d]pyrimidines
LT3097102T (lt) 2015-03-04 2018-01-25 Gilead Sciences, Inc. 4,6-diamino-pirido[3,2-d]pirimidino junginiai, moduliuojantys į toll panašius receptorius
WO2018045150A1 (en) 2016-09-02 2018-03-08 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
CN109923106B (zh) 2016-09-02 2022-09-13 吉利德科学公司 toll样受体调节剂化合物
TW202212339A (zh) 2019-04-17 2022-04-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI879779B (zh) 2019-06-28 2025-04-11 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
DE3323932A1 (de) * 1983-07-02 1985-01-10 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Also Published As

Publication number Publication date
AU576924B2 (en) 1988-09-08
ES549806A0 (es) 1987-07-16
EP0185259A2 (de) 1986-06-25
GR852996B (OSRAM) 1986-04-16
NZ214522A (en) 1988-07-28
EP0185259A3 (de) 1989-03-01
IL77294A (en) 1989-02-28
ES8707238A1 (es) 1987-07-16
CA1252783A (en) 1989-04-18
PT81650A (de) 1986-01-01
FI82696C (fi) 1991-04-10
NO161373B (no) 1989-05-02
DE3445298A1 (de) 1986-06-12
PT81650B (pt) 1988-04-21
DK161327C (da) 1991-12-09
DK572685D0 (da) 1985-12-11
DK572685A (da) 1986-06-13
FI854862A0 (fi) 1985-12-10
ZA859462B (en) 1987-07-29
JPS61140585A (ja) 1986-06-27
NO854965L (no) 1986-06-13
FI854862A7 (fi) 1986-06-13
FI82696B (fi) 1990-12-31
AU5123285A (en) 1986-06-19
DK161327B (da) 1991-06-24
PH24451A (en) 1990-06-25

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