IL77294A - 2-piperazino-4,7-di(cyclo)amino piperidine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
2-piperazino-4,7-di(cyclo)amino piperidine derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL77294A IL77294A IL77294A IL7729485A IL77294A IL 77294 A IL77294 A IL 77294A IL 77294 A IL77294 A IL 77294A IL 7729485 A IL7729485 A IL 7729485A IL 77294 A IL77294 A IL 77294A
- Authority
- IL
- Israel
- Prior art keywords
- piperazino
- cyclo
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
- C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843445298 DE3445298A1 (en) | 1984-12-12 | 1984-12-12 | NEW PTERIDINE, METHOD FOR THE PRODUCTION AND USE THEREOF AS INTERMEDIATE PRODUCTS OR AS A MEDICINAL PRODUCT |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL77294A true IL77294A (en) | 1989-02-28 |
Family
ID=6252576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL77294A IL77294A (en) | 1984-12-12 | 1985-12-11 | 2-piperazino-4,7-di(cyclo)amino piperidine derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0185259A3 (en) |
| JP (1) | JPS61140585A (en) |
| AU (1) | AU576924B2 (en) |
| CA (1) | CA1252783A (en) |
| DE (1) | DE3445298A1 (en) |
| DK (1) | DK161327C (en) |
| ES (1) | ES8707238A1 (en) |
| FI (1) | FI82696C (en) |
| GR (1) | GR852996B (en) |
| IL (1) | IL77294A (en) |
| NO (1) | NO161373C (en) |
| NZ (1) | NZ214522A (en) |
| PH (1) | PH24451A (en) |
| PT (1) | PT81650B (en) |
| ZA (1) | ZA859462B (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7276506B2 (en) | 1998-12-28 | 2007-10-02 | 4 Aza Bioscience Nv | Immunosuppressive effects of pteridine derivatives |
| WO2005021003A2 (en) * | 2003-08-29 | 2005-03-10 | 4 Aza Bioscience Nv | Immunosuppressive effects of pteridine derivatives |
| YU102503A (en) * | 2001-06-28 | 2006-08-17 | Pliva D.D. | Fused pyrimidine dhfr inhibitors as antibacterials |
| DE10202468A1 (en) * | 2002-01-23 | 2004-09-30 | Faustus Forschungs Cie. Translational Cancer Research Gmbh | Pteridine derivatives, process for their preparation and their use |
| GB2407089A (en) * | 2003-10-17 | 2005-04-20 | 4 Aza Bioscience Nv | Pteridine derivatives |
| PT1673092E (en) * | 2003-10-17 | 2007-11-23 | 4 Aza Ip Nv | Heterocycle-substituted pteridine derivatives and their use in therapy |
| JP2007526323A (en) * | 2004-03-04 | 2007-09-13 | ニューロジェン・コーポレーション | Arylalkylamino substituted quinazoline analogs |
| DE102004057645A1 (en) * | 2004-11-29 | 2006-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New substituted pteridine compounds, useful as phosphodiesterase 4 inhibitors for treating e.g. inflammatory diseases, cancer, asthma, ulcerative colitis, depression and schizophrenia |
| DE102004057594A1 (en) * | 2004-11-29 | 2006-06-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Substitute pteridine for the treatment of inflammatory diseases |
| DE102004057595A1 (en) | 2004-11-29 | 2006-06-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Substituted pteridines for the treatment of inflammatory diseases |
| DE102004057618A1 (en) | 2004-11-29 | 2006-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Substituted pteridines for the treatment of inflammatory diseases |
| WO2007060404A1 (en) * | 2005-11-22 | 2007-05-31 | Kudos Pharmaceuticals Limited | PYRIDO-,PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS |
| RU2445315C2 (en) * | 2005-11-22 | 2012-03-20 | Кудос Фармасьютиклз Лимитед | PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AND USE THEREOF AS mTOR INHIBITORS |
| EP2032585B1 (en) | 2006-05-24 | 2014-07-23 | Boehringer Ingelheim International GmbH | Substituted pteridines as therapeutic agents |
| US10144736B2 (en) | 2006-07-20 | 2018-12-04 | Gilead Sciences, Inc. | Substituted pteridines useful for the treatment and prevention of viral infections |
| US9259426B2 (en) | 2006-07-20 | 2016-02-16 | Gilead Sciences, Inc. | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections |
| WO2008023161A1 (en) | 2006-08-23 | 2008-02-28 | Kudos Pharmaceuticals Limited | 2-methylmorpholine pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors |
| US8198441B2 (en) | 2008-06-20 | 2012-06-12 | Astrazeneca Ab | Process for the preparation of novel pyridopyrazines as mTOR kinase inhibitors |
| KR101756050B1 (en) | 2015-03-04 | 2017-07-07 | 길리애드 사이언시즈, 인코포레이티드 | Toll like receptor modulator compounds |
| EP3507288B1 (en) | 2016-09-02 | 2020-08-26 | Gilead Sciences, Inc. | 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators |
| EP3507276B1 (en) | 2016-09-02 | 2021-11-03 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
| TWI751516B (en) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | Solid forms of a toll-like receptor modulator |
| TWI751517B (en) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | Solid forms of a toll-like receptor modulator |
| TW202115056A (en) | 2019-06-28 | 2021-04-16 | 美商基利科學股份有限公司 | Processes for preparing toll-like receptor modulator compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3159628A (en) * | 1962-05-28 | 1964-12-01 | Smith Kline French Lab | Pteridine-5-oxide derivatives |
| DE3323932A1 (en) * | 1983-07-02 | 1985-01-10 | Dr. Karl Thomae Gmbh, 7950 Biberach | NEW 2-PIPERAZINO-PTERIDINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS COMPOUND |
-
1984
- 1984-12-12 DE DE19843445298 patent/DE3445298A1/en not_active Withdrawn
-
1985
- 1985-12-05 EP EP85115459A patent/EP0185259A3/en not_active Ceased
- 1985-12-10 FI FI854862A patent/FI82696C/en not_active IP Right Cessation
- 1985-12-11 JP JP60278859A patent/JPS61140585A/en active Pending
- 1985-12-11 ES ES549806A patent/ES8707238A1/en not_active Expired
- 1985-12-11 NO NO854965A patent/NO161373C/en unknown
- 1985-12-11 PT PT81650A patent/PT81650B/en not_active IP Right Cessation
- 1985-12-11 NZ NZ214522A patent/NZ214522A/en unknown
- 1985-12-11 IL IL77294A patent/IL77294A/en unknown
- 1985-12-11 DK DK572685A patent/DK161327C/en not_active IP Right Cessation
- 1985-12-11 PH PH33161A patent/PH24451A/en unknown
- 1985-12-11 CA CA000497336A patent/CA1252783A/en not_active Expired
- 1985-12-11 ZA ZA859462A patent/ZA859462B/en unknown
- 1985-12-12 GR GR852996A patent/GR852996B/el unknown
- 1985-12-12 AU AU51232/85A patent/AU576924B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DK161327B (en) | 1991-06-24 |
| EP0185259A2 (en) | 1986-06-25 |
| PT81650A (en) | 1986-01-01 |
| NO161373B (en) | 1989-05-02 |
| CA1252783A (en) | 1989-04-18 |
| DE3445298A1 (en) | 1986-06-12 |
| NZ214522A (en) | 1988-07-28 |
| AU5123285A (en) | 1986-06-19 |
| AU576924B2 (en) | 1988-09-08 |
| FI854862A0 (en) | 1985-12-10 |
| EP0185259A3 (en) | 1989-03-01 |
| DK572685D0 (en) | 1985-12-11 |
| DK161327C (en) | 1991-12-09 |
| JPS61140585A (en) | 1986-06-27 |
| ES549806A0 (en) | 1987-07-16 |
| PH24451A (en) | 1990-06-25 |
| FI82696B (en) | 1990-12-31 |
| ES8707238A1 (en) | 1987-07-16 |
| NO854965L (en) | 1986-06-13 |
| FI854862A (en) | 1986-06-13 |
| PT81650B (en) | 1988-04-21 |
| NO161373C (en) | 1989-08-09 |
| DK572685A (en) | 1986-06-13 |
| FI82696C (en) | 1991-04-10 |
| GR852996B (en) | 1986-04-16 |
| ZA859462B (en) | 1987-07-29 |
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