IL77294A - 2-piperazino-4,7-di(cyclo)amino piperidine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
2-piperazino-4,7-di(cyclo)amino piperidine derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL77294A IL77294A IL77294A IL7729485A IL77294A IL 77294 A IL77294 A IL 77294A IL 77294 A IL77294 A IL 77294A IL 7729485 A IL7729485 A IL 7729485A IL 77294 A IL77294 A IL 77294A
- Authority
- IL
- Israel
- Prior art keywords
- piperazino
- cyclo
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
- C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843445298 DE3445298A1 (en) | 1984-12-12 | 1984-12-12 | NEW PTERIDINE, METHOD FOR THE PRODUCTION AND USE THEREOF AS INTERMEDIATE PRODUCTS OR AS A MEDICINAL PRODUCT |
Publications (1)
Publication Number | Publication Date |
---|---|
IL77294A true IL77294A (en) | 1989-02-28 |
Family
ID=6252576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL77294A IL77294A (en) | 1984-12-12 | 1985-12-11 | 2-piperazino-4,7-di(cyclo)amino piperidine derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0185259A3 (en) |
JP (1) | JPS61140585A (en) |
AU (1) | AU576924B2 (en) |
CA (1) | CA1252783A (en) |
DE (1) | DE3445298A1 (en) |
DK (1) | DK161327C (en) |
ES (1) | ES8707238A1 (en) |
FI (1) | FI82696C (en) |
GR (1) | GR852996B (en) |
IL (1) | IL77294A (en) |
NO (1) | NO161373C (en) |
NZ (1) | NZ214522A (en) |
PH (1) | PH24451A (en) |
PT (1) | PT81650B (en) |
ZA (1) | ZA859462B (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7276506B2 (en) | 1998-12-28 | 2007-10-02 | 4 Aza Bioscience Nv | Immunosuppressive effects of pteridine derivatives |
WO2005021003A2 (en) * | 2003-08-29 | 2005-03-10 | 4 Aza Bioscience Nv | Immunosuppressive effects of pteridine derivatives |
YU102503A (en) * | 2001-06-28 | 2006-08-17 | Pliva D.D. | Fused pyrimidine dhfr inhibitors as antibacterials |
DE10202468A1 (en) * | 2002-01-23 | 2004-09-30 | Faustus Forschungs Cie. Translational Cancer Research Gmbh | Pteridine derivatives, process for their preparation and their use |
GB2407089A (en) * | 2003-10-17 | 2005-04-20 | 4 Aza Bioscience Nv | Pteridine derivatives |
PT1673092E (en) * | 2003-10-17 | 2007-11-23 | 4 Aza Ip Nv | Heterocycle-substituted pteridine derivatives and their use in therapy |
JP2007526323A (en) * | 2004-03-04 | 2007-09-13 | ニューロジェン・コーポレーション | Arylalkylamino substituted quinazoline analogs |
DE102004057645A1 (en) * | 2004-11-29 | 2006-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New substituted pteridine compounds, useful as phosphodiesterase 4 inhibitors for treating e.g. inflammatory diseases, cancer, asthma, ulcerative colitis, depression and schizophrenia |
DE102004057594A1 (en) * | 2004-11-29 | 2006-06-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Substitute pteridine for the treatment of inflammatory diseases |
DE102004057595A1 (en) | 2004-11-29 | 2006-06-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Substituted pteridines for the treatment of inflammatory diseases |
DE102004057618A1 (en) | 2004-11-29 | 2006-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Substituted pteridines for the treatment of inflammatory diseases |
WO2007060404A1 (en) * | 2005-11-22 | 2007-05-31 | Kudos Pharmaceuticals Limited | PYRIDO-,PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS |
RU2445315C2 (en) * | 2005-11-22 | 2012-03-20 | Кудос Фармасьютиклз Лимитед | PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AND USE THEREOF AS mTOR INHIBITORS |
EP2032585B1 (en) | 2006-05-24 | 2014-07-23 | Boehringer Ingelheim International GmbH | Substituted pteridines as therapeutic agents |
US10144736B2 (en) | 2006-07-20 | 2018-12-04 | Gilead Sciences, Inc. | Substituted pteridines useful for the treatment and prevention of viral infections |
US9259426B2 (en) | 2006-07-20 | 2016-02-16 | Gilead Sciences, Inc. | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections |
WO2008023161A1 (en) | 2006-08-23 | 2008-02-28 | Kudos Pharmaceuticals Limited | 2-methylmorpholine pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors |
US8198441B2 (en) | 2008-06-20 | 2012-06-12 | Astrazeneca Ab | Process for the preparation of novel pyridopyrazines as mTOR kinase inhibitors |
KR101756050B1 (en) | 2015-03-04 | 2017-07-07 | 길리애드 사이언시즈, 인코포레이티드 | Toll like receptor modulator compounds |
EP3507288B1 (en) | 2016-09-02 | 2020-08-26 | Gilead Sciences, Inc. | 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators |
EP3507276B1 (en) | 2016-09-02 | 2021-11-03 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
TWI751516B (en) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | Solid forms of a toll-like receptor modulator |
TWI751517B (en) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | Solid forms of a toll-like receptor modulator |
TW202115056A (en) | 2019-06-28 | 2021-04-16 | 美商基利科學股份有限公司 | Processes for preparing toll-like receptor modulator compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3159628A (en) * | 1962-05-28 | 1964-12-01 | Smith Kline French Lab | Pteridine-5-oxide derivatives |
DE3323932A1 (en) * | 1983-07-02 | 1985-01-10 | Dr. Karl Thomae Gmbh, 7950 Biberach | NEW 2-PIPERAZINO-PTERIDINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS COMPOUND |
-
1984
- 1984-12-12 DE DE19843445298 patent/DE3445298A1/en not_active Withdrawn
-
1985
- 1985-12-05 EP EP85115459A patent/EP0185259A3/en not_active Ceased
- 1985-12-10 FI FI854862A patent/FI82696C/en not_active IP Right Cessation
- 1985-12-11 JP JP60278859A patent/JPS61140585A/en active Pending
- 1985-12-11 ES ES549806A patent/ES8707238A1/en not_active Expired
- 1985-12-11 NO NO854965A patent/NO161373C/en unknown
- 1985-12-11 PT PT81650A patent/PT81650B/en not_active IP Right Cessation
- 1985-12-11 NZ NZ214522A patent/NZ214522A/en unknown
- 1985-12-11 IL IL77294A patent/IL77294A/en unknown
- 1985-12-11 DK DK572685A patent/DK161327C/en not_active IP Right Cessation
- 1985-12-11 PH PH33161A patent/PH24451A/en unknown
- 1985-12-11 CA CA000497336A patent/CA1252783A/en not_active Expired
- 1985-12-11 ZA ZA859462A patent/ZA859462B/en unknown
- 1985-12-12 GR GR852996A patent/GR852996B/el unknown
- 1985-12-12 AU AU51232/85A patent/AU576924B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
DK161327B (en) | 1991-06-24 |
EP0185259A2 (en) | 1986-06-25 |
PT81650A (en) | 1986-01-01 |
NO161373B (en) | 1989-05-02 |
CA1252783A (en) | 1989-04-18 |
DE3445298A1 (en) | 1986-06-12 |
NZ214522A (en) | 1988-07-28 |
AU5123285A (en) | 1986-06-19 |
AU576924B2 (en) | 1988-09-08 |
FI854862A0 (en) | 1985-12-10 |
EP0185259A3 (en) | 1989-03-01 |
DK572685D0 (en) | 1985-12-11 |
DK161327C (en) | 1991-12-09 |
JPS61140585A (en) | 1986-06-27 |
ES549806A0 (en) | 1987-07-16 |
PH24451A (en) | 1990-06-25 |
FI82696B (en) | 1990-12-31 |
ES8707238A1 (en) | 1987-07-16 |
NO854965L (en) | 1986-06-13 |
FI854862A (en) | 1986-06-13 |
PT81650B (en) | 1988-04-21 |
NO161373C (en) | 1989-08-09 |
DK572685A (en) | 1986-06-13 |
FI82696C (en) | 1991-04-10 |
GR852996B (en) | 1986-04-16 |
ZA859462B (en) | 1987-07-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL77294A (en) | 2-piperazino-4,7-di(cyclo)amino piperidine derivatives,their preparation and pharmaceutical compositions containing them | |
IL85136A0 (en) | Peptide derivatives,their preparation and pharmaceutical compositions containing them | |
IL80296A (en) | Phenylpyridone derivatives,their preparation and pharmaceutical compositions containing them | |
IL79323A0 (en) | Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them | |
EP0163550A3 (en) | New mitomycin derivatives, preparation thereof and pharmaceutical compositions containing them | |
IL79309A0 (en) | (heterocyclic substituted-phenoxy)alkyl-isoxazoles and-furans,their preparation and pharmaceutical compositions containing them | |
IL89881A0 (en) | Peptide derivatives,their production and pharmaceutical compositions containing them | |
IL76675A (en) | Piperidine derivatives,their preparation and pharmaceutical compositions containing them | |
IL92633A0 (en) | Piperidine derivatives,their preparation and pharmaceutical compositions containing them | |
IL79402A (en) | Poly-4-aminopyrrole-2-carboxamido derivatives,their preparation and pharmaceutical compositions containing them | |
IL79039A0 (en) | 4-oxoquinolinesulfonamides,their preparation and pharmaceutical compositions containing them | |
IL76312A (en) | Xenocoumacins and derivatives thereof,their preparation and pharmaceutical compositions containing them | |
EP0159652A3 (en) | 4-phenylphthalazine derivatives, their preparation and pharmaceutical compositions containing them | |
DE3561808D1 (en) | Phenylnonatetraenic-acid derivatives, their preparation and pharmaceutical compositions containing them | |
IL78432A (en) | Dichloroaniline derivatives,their preparation and pharmaceutical compositions containing them | |
AU4963985A (en) | Carboxyalkyldipeptides, their preparation and pharmaceutical compositions containing them | |
IL96216A0 (en) | Peptide derivatives,their preparation and pharmaceutical compositions containing them | |
GB2196958B (en) | Halo-homostatin peptide derivatives ,their preparation and pharmaceutical compositions containing them | |
IL75329A (en) | Acylated sugar peptide derivatives,and pharmaceutical compositions containing them | |
ZA857911B (en) | Piperidine derivatives,their preparation and pharmaceutical compositions containing them | |
IL77614A (en) | Interfuranylene-prostacyclin derivatives,their preparation and pharmaceutical compositions containing them | |
AU589429B2 (en) | Novel 11-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions | |
IL76282A0 (en) | Amino acid derivatives,their preparation and pharmaceutical compositions containing them | |
DE3570667D1 (en) | 3-aminopropyloxyphenyl derivatives, their preparation and pharmaceutical compositions containing them | |
IL78534A0 (en) | Eburnamenine derivatives,their preparation and pharmaceutical compositions containing them |