NO157420C - Analogifremgangsmaate for fremstilling av teraputisk aktive 2-acylaminomethyl-1h-2,3-dihydro-1,4-benzodiazepin-forbindelser. - Google Patents
Analogifremgangsmaate for fremstilling av teraputisk aktive 2-acylaminomethyl-1h-2,3-dihydro-1,4-benzodiazepin-forbindelser.Info
- Publication number
- NO157420C NO157420C NO822037A NO822037A NO157420C NO 157420 C NO157420 C NO 157420C NO 822037 A NO822037 A NO 822037A NO 822037 A NO822037 A NO 822037A NO 157420 C NO157420 C NO 157420C
- Authority
- NO
- Norway
- Prior art keywords
- radical
- acylaminomethyl
- dihydro
- hydrogen atom
- theraputic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813124013 DE3124013A1 (de) | 1981-06-19 | 1981-06-19 | 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO822037L NO822037L (no) | 1982-12-20 |
| NO157420B NO157420B (no) | 1987-12-07 |
| NO157420C true NO157420C (no) | 1988-03-16 |
Family
ID=6134869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO822037A NO157420C (no) | 1981-06-19 | 1982-06-18 | Analogifremgangsmaate for fremstilling av teraputisk aktive 2-acylaminomethyl-1h-2,3-dihydro-1,4-benzodiazepin-forbindelser. |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US4497740A (no) |
| EP (1) | EP0068240B1 (no) |
| JP (1) | JPS58968A (no) |
| AT (1) | ATE15802T1 (no) |
| AU (1) | AU547857B2 (no) |
| CA (1) | CA1188299A (no) |
| DD (1) | DD202553A5 (no) |
| DE (2) | DE3124013A1 (no) |
| DK (1) | DK274082A (no) |
| ES (1) | ES512844A0 (no) |
| FI (1) | FI68049C (no) |
| GR (1) | GR76499B (no) |
| HU (1) | HU188178B (no) |
| IE (1) | IE53464B1 (no) |
| IL (1) | IL66076A (no) |
| NO (1) | NO157420C (no) |
| NZ (1) | NZ201007A (no) |
| PH (1) | PH17911A (no) |
| PT (1) | PT74971B (no) |
| SU (1) | SU1245259A3 (no) |
| ZA (1) | ZA823780B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4724237A (en) * | 1984-06-26 | 1988-02-09 | Merck & Co., Inc. | 2-substituted-aminomethyl-1,4-benzodiazepines |
| US4899425A (en) * | 1986-11-14 | 1990-02-13 | Mahlo Gmbh & Co. Kg. | Apparatus for straightening weft yarns in fabrics |
| US6458784B1 (en) | 1994-06-29 | 2002-10-01 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
| US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
| CN102548943B (zh) * | 2009-09-18 | 2014-07-02 | 三菱瓦斯化学株式会社 | 环己基烷基酮类的制造方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US28315A (en) * | 1860-05-15 | Improvement in method of decomposing fats into fatty acids and glycerine | ||
| NL122319C (no) * | 1961-06-20 | |||
| USRE28315E (en) | 1964-06-15 | 1975-01-21 | Cooc.hi | |
| US3560482A (en) * | 1967-12-08 | 1971-02-02 | Sumitomo Chemical Co | Method for producing benzodiazepine derivatives |
| US3546212A (en) * | 1968-06-12 | 1970-12-08 | Hoffmann La Roche | Oxidation of benzodiazepines with ruthenium tetroxide |
| US3773765A (en) * | 1971-08-18 | 1973-11-20 | Upjohn Co | S-triazino(1,2-a)(1,4)benzodiazepine-1,3-(2h,4h and 2h,5h)diones |
| US3847935A (en) * | 1972-04-12 | 1974-11-12 | Upjohn Co | 5-substituted 1-(3h,1,4-benzodiazepin-2-yl)-2-imidazolidinones |
| DE2265371C3 (de) * | 1972-05-03 | 1980-12-11 | Kali-Chemie Ag, 3000 Hannover | N-(3-Benzoylaminopropyl)-aniline |
| US4244869A (en) * | 1972-05-03 | 1981-01-13 | Kali-Chemie A.G. | Benzodiazepine derivatives and process of making them |
| DE2314993A1 (de) * | 1973-03-26 | 1974-10-03 | Kali Chemie Pharma Gmbh | Neue benzodiazepinderivate und verfahren zu deren herstellung |
| DE2353187A1 (de) * | 1973-05-02 | 1974-11-14 | Kali Chemie Ag | Neue benzodiazepinderivate |
| DE2353160C2 (de) * | 1973-05-02 | 1986-07-17 | Kali-Chemie Ag, 3000 Hannover | 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine, ihre Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel |
| DE2353165C2 (de) * | 1973-05-03 | 1983-06-09 | Kali-Chemie Ag, 3000 Hannover | 1-Methyl-3-hydroxy-6-(2-chlorphenyl)-1,2,3,4-tetrahydro-1,5-benzodiazocinderivate |
| US3925358A (en) * | 1973-07-27 | 1975-12-09 | Hoffmann La Roche | 1-Lower alkyl-2-substituted-1,4-benzodiazepines |
| US4368159A (en) * | 1978-05-15 | 1983-01-11 | Hoffmann-La Roche Inc. | Intermediates to produce imidazodiazepines |
| DE2952279A1 (de) * | 1979-12-24 | 1981-06-25 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Neue 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| HU186760B (en) * | 1981-03-12 | 1985-09-30 | Gyogyszerkutato Intezet | Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives |
-
1981
- 1981-06-19 DE DE19813124013 patent/DE3124013A1/de not_active Withdrawn
-
1982
- 1982-05-28 PT PT74971A patent/PT74971B/pt unknown
- 1982-05-28 ZA ZA823780A patent/ZA823780B/xx unknown
- 1982-06-04 ES ES512844A patent/ES512844A0/es active Granted
- 1982-06-08 US US06/386,303 patent/US4497740A/en not_active Expired - Fee Related
- 1982-06-11 JP JP57099446A patent/JPS58968A/ja active Granted
- 1982-06-12 AT AT82105139T patent/ATE15802T1/de not_active IP Right Cessation
- 1982-06-12 EP EP82105139A patent/EP0068240B1/de not_active Expired
- 1982-06-12 DE DE8282105139T patent/DE3266521D1/de not_active Expired
- 1982-06-15 FI FI822148A patent/FI68049C/fi not_active IP Right Cessation
- 1982-06-15 DD DD82240747A patent/DD202553A5/de unknown
- 1982-06-17 GR GR68467A patent/GR76499B/el unknown
- 1982-06-17 IL IL66076A patent/IL66076A/xx unknown
- 1982-06-18 SU SU823453651A patent/SU1245259A3/ru active
- 1982-06-18 NZ NZ201007A patent/NZ201007A/en unknown
- 1982-06-18 HU HU821988A patent/HU188178B/hu unknown
- 1982-06-18 AU AU84991/82A patent/AU547857B2/en not_active Ceased
- 1982-06-18 NO NO822037A patent/NO157420C/no unknown
- 1982-06-18 CA CA000405518A patent/CA1188299A/en not_active Expired
- 1982-06-18 PH PH27446A patent/PH17911A/en unknown
- 1982-06-18 DK DK274082A patent/DK274082A/da not_active Application Discontinuation
- 1982-06-21 IE IE1468/82A patent/IE53464B1/en unknown
-
1986
- 1986-04-03 US US06/847,112 patent/US4649137A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI68049B (fi) | 1985-03-29 |
| IE53464B1 (en) | 1988-11-23 |
| JPS58968A (ja) | 1983-01-06 |
| ATE15802T1 (de) | 1985-10-15 |
| CA1188299A (en) | 1985-06-04 |
| EP0068240B1 (de) | 1985-09-25 |
| DK274082A (da) | 1982-12-20 |
| GR76499B (no) | 1984-08-10 |
| FI822148L (fi) | 1982-12-20 |
| FI68049C (fi) | 1985-07-10 |
| PT74971A (en) | 1982-06-01 |
| AU547857B2 (en) | 1985-11-07 |
| ES8304564A1 (es) | 1983-03-01 |
| IE821468L (en) | 1982-12-19 |
| PT74971B (en) | 1983-12-29 |
| NO822037L (no) | 1982-12-20 |
| ES512844A0 (es) | 1983-03-01 |
| AU8499182A (en) | 1982-12-23 |
| HU188178B (en) | 1986-03-28 |
| EP0068240A1 (de) | 1983-01-05 |
| US4649137A (en) | 1987-03-10 |
| FI822148A0 (fi) | 1982-06-15 |
| US4497740A (en) | 1985-02-05 |
| PH17911A (en) | 1985-01-25 |
| DE3266521D1 (en) | 1985-10-31 |
| ZA823780B (en) | 1983-03-30 |
| DE3124013A1 (de) | 1982-12-30 |
| NZ201007A (en) | 1985-05-31 |
| NO157420B (no) | 1987-12-07 |
| DD202553A5 (de) | 1983-09-21 |
| IL66076A0 (en) | 1982-09-30 |
| JPH0433795B2 (no) | 1992-06-04 |
| SU1245259A3 (ru) | 1986-07-15 |
| IL66076A (en) | 1986-03-31 |
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