NO148488C - Analogifremgangsmaate til fremstilling av terapeutisk aktive acyl-benzimidazol-2-derivater - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk aktive acyl-benzimidazol-2-derivater

Info

Publication number
NO148488C
NO148488C NO772962A NO772962A NO148488C NO 148488 C NO148488 C NO 148488C NO 772962 A NO772962 A NO 772962A NO 772962 A NO772962 A NO 772962A NO 148488 C NO148488 C NO 148488C
Authority
NO
Norway
Prior art keywords
benzimidazole
derivatives
preparation
therapeutic active
active acyl
Prior art date
Application number
NO772962A
Other languages
English (en)
Norwegian (no)
Other versions
NO148488B (no
NO772962L (no
Inventor
Ernst Habicht
Pier Giorgio Ferrini
Alfred Sallmann
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO772962L publication Critical patent/NO772962L/no
Publication of NO148488B publication Critical patent/NO148488B/no
Publication of NO148488C publication Critical patent/NO148488C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/807—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
NO772962A 1976-08-27 1977-08-26 Analogifremgangsmaate til fremstilling av terapeutisk aktive acyl-benzimidazol-2-derivater NO148488C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75684A LU75684A1 (xx) 1976-08-27 1976-08-27

Publications (3)

Publication Number Publication Date
NO772962L NO772962L (no) 1978-02-28
NO148488B NO148488B (no) 1983-07-11
NO148488C true NO148488C (no) 1983-10-19

Family

ID=19728336

Family Applications (1)

Application Number Title Priority Date Filing Date
NO772962A NO148488C (no) 1976-08-27 1977-08-26 Analogifremgangsmaate til fremstilling av terapeutisk aktive acyl-benzimidazol-2-derivater

Country Status (32)

Country Link
US (3) US4141982A (xx)
JP (1) JPS5328172A (xx)
AR (6) AR224610A1 (xx)
AT (1) AT359060B (xx)
AU (1) AU517209B2 (xx)
BE (1) BE858157A (xx)
CA (1) CA1098526A (xx)
CH (8) CH631973A5 (xx)
DD (1) DD132735A5 (xx)
DE (1) DE2737462A1 (xx)
DK (1) DK381277A (xx)
ES (7) ES461906A1 (xx)
FI (1) FI68230C (xx)
FR (1) FR2362841A1 (xx)
GB (2) GB1595913A (xx)
GR (1) GR72908B (xx)
HK (1) HK93784A (xx)
HU (2) HU186765B (xx)
IE (1) IE45665B1 (xx)
IL (1) IL52820A (xx)
LU (1) LU75684A1 (xx)
MY (1) MY8500936A (xx)
NL (1) NL7709471A (xx)
NO (1) NO148488C (xx)
NZ (1) NZ185035A (xx)
OA (1) OA05753A (xx)
PL (4) PL105527B1 (xx)
PT (1) PT66947B (xx)
SE (1) SE434397B (xx)
SG (1) SG70784G (xx)
SU (7) SU882410A3 (xx)
ZA (1) ZA775182B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312873A (en) * 1978-09-29 1982-01-26 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4322431A (en) * 1979-02-09 1982-03-30 Ciba-Geigy Corporation Pharmaceutical preparations containing benzimidazole 2-derivatives
US4492708A (en) * 1982-09-27 1985-01-08 Eli Lilly And Company Antiviral benzimidazoles
ES2025645T3 (es) * 1987-02-03 1992-04-01 W.R. Grace & Co.-Conn. (A Connecticut Corp.) Un metodo para tratar sistemas acuosos o no acuosos con biocidas.
JPH04197628A (ja) * 1990-11-28 1992-07-17 Sekisui Chem Co Ltd 壁パネルの製造方法
US5216003A (en) * 1992-01-02 1993-06-01 G. D. Searle & Co. Diacid-containing benzimidazole compounds for treatment of neurotoxic injury
FR2751649B1 (fr) * 1996-07-26 1998-08-28 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US9663703B2 (en) 2014-04-25 2017-05-30 James George Clements Method and compositions for enhanced oil recovery
CN109467512B (zh) * 2018-12-18 2021-06-08 苏州开元民生科技股份有限公司 一种3,4-二氨基-二苯甲酮的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB766749A (en) 1954-01-11 1957-01-23 Aschaffenburger Zellstoffwerke Benzimidazole cobalamines and process for their preparation and separation
US3318889A (en) * 1963-10-14 1967-05-09 S B Penick & Company 2-benzimidazole carbamates
DE1923481A1 (de) * 1969-05-08 1970-11-12 Hoechst Ag Verfahren zur Herstellung von Amiden und Estern der 1-Hydroxy-benzimidazol-2-carbonsaeure
NL7013343A (xx) * 1969-09-26 1971-03-30
BE759237A (fr) * 1969-11-21 1971-05-01 Montedison Spa Procede de preparation d'amides a partir de composes heterocycliques azotes
BE792402A (fr) * 1971-12-07 1973-06-07 Ciba Geigy Composes heterocycliques azotes et medicaments anthelminthiqueset antimicrobiens qui en contiennent
US4026936A (en) * 1975-08-07 1977-05-31 Hoffmann-La Roche Inc. Anthelmintic pyridine and thiazole substituted benzimidazole carbamates

Also Published As

Publication number Publication date
AR227621A1 (es) 1982-11-30
HU180700B (en) 1983-04-29
GR72908B (xx) 1984-01-04
MY8500936A (en) 1985-12-31
CH637120A5 (de) 1983-07-15
IE45665L (en) 1978-02-27
ES471688A1 (es) 1979-10-16
NO148488B (no) 1983-07-11
HU186765B (en) 1985-09-30
GB1595914A (en) 1981-08-19
FI68230B (fi) 1985-04-30
JPS5328172A (en) 1978-03-16
IL52820A (en) 1981-02-27
NO772962L (no) 1978-02-28
ES471686A1 (es) 1979-10-16
SU831074A3 (ru) 1981-05-15
CH637121A5 (de) 1983-07-15
ATA620677A (de) 1980-03-15
ES471687A1 (es) 1979-10-16
PT66947A (en) 1977-09-01
SE434397B (sv) 1984-07-23
LU75684A1 (xx) 1978-04-13
ES479189A0 (es) 1981-09-01
FI772521A (fi) 1978-02-28
SU784766A3 (ru) 1980-11-30
AR230990A1 (es) 1984-08-31
US4141982A (en) 1979-02-27
DE2737462A1 (de) 1978-03-02
IE45665B1 (en) 1982-10-20
PL105527B1 (pl) 1979-10-31
SG70784G (en) 1985-03-15
NL7709471A (nl) 1978-03-01
CH631974A5 (de) 1982-09-15
IL52820A0 (en) 1977-10-31
BE858157A (fr) 1978-02-27
US4213993A (en) 1980-07-22
AT359060B (de) 1980-10-27
PL110215B1 (en) 1980-07-31
AU517209B2 (en) 1981-07-16
AR224610A1 (es) 1981-12-30
PL108853B1 (en) 1980-05-31
CH631975A5 (de) 1982-09-15
FI68230C (fi) 1985-08-12
HK93784A (en) 1984-12-07
PL200449A1 (pl) 1978-05-22
OA05753A (fr) 1981-05-31
ZA775182B (en) 1978-07-26
DK381277A (da) 1978-02-28
US4344957A (en) 1982-08-17
ES8106706A1 (es) 1981-09-01
ES471689A1 (es) 1979-10-16
ES461906A1 (es) 1978-12-01
ES471690A1 (es) 1979-10-16
NZ185035A (en) 1981-05-29
SU745365A3 (ru) 1980-06-30
GB1595913A (en) 1981-08-19
AU2825577A (en) 1979-03-01
AR222318A1 (es) 1981-05-15
CH631973A5 (de) 1982-09-15
DD132735A5 (de) 1978-10-25
AR225889A1 (es) 1982-05-14
CH632253A5 (de) 1982-09-30
SE7709615L (sv) 1978-02-28
AR231536A1 (es) 1984-12-28
SU923368A3 (ru) 1982-04-23
CH632749A5 (de) 1982-10-29
FR2362841A1 (fr) 1978-03-24
PL112665B1 (en) 1980-10-31
PT66947B (en) 1979-02-07
CH634305A5 (de) 1983-01-31
JPS6231706B2 (xx) 1987-07-09
SU882410A3 (ru) 1981-11-15
SU888819A3 (ru) 1981-12-07
FR2362841B1 (xx) 1981-11-20
CA1098526A (en) 1981-03-31
SU843744A3 (ru) 1981-06-30

Similar Documents

Publication Publication Date Title
NO147243C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalanderivater
NO149586C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive polypeptider
NO151321C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater
NO151463C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater
NO148148C (no) Fremgangsmaate til fremstilling av terapeutisk aktive 4-hydroksy-2-pyrrolidinonderivater
NO151411C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-aryloksy-2-hydroksy-3-alkylenaminopropan-derivater
NO148453C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive spirohydantoinderivater
NO800881L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolonderivater
NO144848C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 4-hydroksyfenylalkanolamin-derivater
NO148777C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive antrakinon-derivater
NO150044C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrazol-derivater
NO145198C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktivt 1,2-benzisotia-zolinon-3
NO145951C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazolinderivater
NO149313C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridobenzodiazepiner
NO149037C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridobenzodiazepiner
NO148291C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive basisk substituerte teofyllinderivater
NO148488C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive acyl-benzimidazol-2-derivater
NO145163C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive antitumorglykosider
NO151660C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazolderivater.
NO143903C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-fluorpyrimidin-4-on-derivater
NO780644L (no) Fremgangsmaate til fremstilling av terapeutisk virksomme 9-hydroksyetoksymetylguanin-derivater
NO152172C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive spiro-kinolyl-hydantoin-derivater
NO146600C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazolderivater
NO147273C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive cykloheksadien-derivater
NO152556C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive antracen-biskarbonylhydrazoner