NO123738B - - Google Patents
Download PDFInfo
- Publication number
- NO123738B NO123738B NO2016/69A NO201669A NO123738B NO 123738 B NO123738 B NO 123738B NO 2016/69 A NO2016/69 A NO 2016/69A NO 201669 A NO201669 A NO 201669A NO 123738 B NO123738 B NO 123738B
- Authority
- NO
- Norway
- Prior art keywords
- pimaricin
- approx
- soluble
- micrograms
- days
- Prior art date
Links
- NCXMLFZGDNKEPB-UHFFFAOYSA-N Pimaricin Natural products OC1C(N)C(O)C(C)OC1OC1C=CC=CC=CC=CCC(C)OC(=O)C=CC2OC2CC(O)CC(O)(CC(O)C2C(O)=O)OC2C1 NCXMLFZGDNKEPB-UHFFFAOYSA-N 0.000 claims description 61
- 229960003255 natamycin Drugs 0.000 claims description 61
- NCXMLFZGDNKEPB-FFPOYIOWSA-N natamycin Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C[C@@H](C)OC(=O)/C=C/[C@H]2O[C@@H]2C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 NCXMLFZGDNKEPB-FFPOYIOWSA-N 0.000 claims description 61
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 39
- 239000002609 medium Substances 0.000 claims description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 25
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 20
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims description 15
- 230000003115 biocidal effect Effects 0.000 claims description 13
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 12
- 239000000126 substance Substances 0.000 claims description 12
- 241000970906 Streptomyces natalensis Species 0.000 claims description 11
- 235000015097 nutrients Nutrition 0.000 claims description 11
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 10
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 241000233866 Fungi Species 0.000 claims description 6
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 6
- 229960000583 acetic acid Drugs 0.000 claims description 6
- 239000012362 glacial acetic acid Substances 0.000 claims description 6
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 claims description 6
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 5
- 229910001854 alkali hydroxide Inorganic materials 0.000 claims description 5
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims description 5
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 5
- 238000000605 extraction Methods 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 238000010521 absorption reaction Methods 0.000 claims description 4
- 150000001720 carbohydrates Chemical class 0.000 claims description 4
- 229910052757 nitrogen Inorganic materials 0.000 claims description 4
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims description 3
- 241000894007 species Species 0.000 claims description 3
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims description 2
- 150000001298 alcohols Chemical class 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 claims description 2
- JGJLWPGRMCADHB-UHFFFAOYSA-N hypobromite Inorganic materials Br[O-] JGJLWPGRMCADHB-UHFFFAOYSA-N 0.000 claims description 2
- 230000003071 parasitic effect Effects 0.000 claims description 2
- 230000008569 process Effects 0.000 claims description 2
- 229910021578 Iron(III) chloride Inorganic materials 0.000 claims 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 claims 1
- 230000000694 effects Effects 0.000 description 18
- 238000000855 fermentation Methods 0.000 description 18
- 230000004151 fermentation Effects 0.000 description 18
- 239000007788 liquid Substances 0.000 description 15
- 230000012010 growth Effects 0.000 description 14
- 240000007817 Olea europaea Species 0.000 description 13
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
- 239000000243 solution Substances 0.000 description 12
- 239000000049 pigment Substances 0.000 description 11
- 238000011081 inoculation Methods 0.000 description 10
- 229920001817 Agar Polymers 0.000 description 9
- 239000008272 agar Substances 0.000 description 9
- 239000000284 extract Substances 0.000 description 9
- 241000699666 Mus <mouse, genus> Species 0.000 description 7
- 239000006071 cream Substances 0.000 description 7
- 239000013078 crystal Substances 0.000 description 7
- 239000000706 filtrate Substances 0.000 description 7
- 239000000047 product Substances 0.000 description 6
- 240000004713 Pisum sativum Species 0.000 description 5
- 235000010582 Pisum sativum Nutrition 0.000 description 5
- 238000005273 aeration Methods 0.000 description 5
- 238000011534 incubation Methods 0.000 description 5
- 238000002955 isolation Methods 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 241001481789 Rupicapra Species 0.000 description 4
- 241000187747 Streptomyces Species 0.000 description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 description 4
- 239000011707 mineral Substances 0.000 description 4
- 235000010755 mineral Nutrition 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 235000011121 sodium hydroxide Nutrition 0.000 description 4
- 159000000000 sodium salts Chemical class 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 244000061775 Olea africana Species 0.000 description 3
- 235000002852 Olea africana Nutrition 0.000 description 3
- 241000700159 Rattus Species 0.000 description 3
- 244000061456 Solanum tuberosum Species 0.000 description 3
- 235000002595 Solanum tuberosum Nutrition 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 229910021538 borax Inorganic materials 0.000 description 3
- 239000001110 calcium chloride Substances 0.000 description 3
- 229910001628 calcium chloride Inorganic materials 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 235000013312 flour Nutrition 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 239000002244 precipitate Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 238000000746 purification Methods 0.000 description 3
- 239000004328 sodium tetraborate Substances 0.000 description 3
- 235000010339 sodium tetraborate Nutrition 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 241000186361 Actinobacteria <class> Species 0.000 description 2
- 241001273451 Ascochyta pisi Species 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 2
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000002021 butanolic extract Substances 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 230000000855 fungicidal effect Effects 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000002329 infrared spectrum Methods 0.000 description 2
- PHTQWCKDNZKARW-UHFFFAOYSA-N isoamylol Chemical compound CC(C)CCO PHTQWCKDNZKARW-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000000877 morphologic effect Effects 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 229940072033 potash Drugs 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 235000015320 potassium carbonate Nutrition 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- DLYUQMMRRRQYAE-UHFFFAOYSA-N tetraphosphorus decaoxide Chemical compound O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 2
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 1
- 241000203809 Actinomycetales Species 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 235000017060 Arachis glabrata Nutrition 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 235000010777 Arachis hypogaea Nutrition 0.000 description 1
- 235000018262 Arachis monticola Nutrition 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 241000222290 Cladosporium Species 0.000 description 1
- 241000252095 Congridae Species 0.000 description 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 241000223218 Fusarium Species 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 241000235070 Saccharomyces Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 241000005602 Trisetum flavescens Species 0.000 description 1
- 241000082085 Verticillium <Phyllachorales> Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 238000000862 absorption spectrum Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000010533 azeotropic distillation Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 210000000805 cytoplasm Anatomy 0.000 description 1
- 239000012225 czapek media Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000000921 elemental analysis Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 235000021323 fish oil Nutrition 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- -1 glycerol Chemical class 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 238000003898 horticulture Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000000401 methanolic extract Substances 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- KELXKDDAALYTDI-BTVCFUMJSA-N nitric acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound O[N+]([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O KELXKDDAALYTDI-BTVCFUMJSA-N 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 230000003032 phytopathogenic effect Effects 0.000 description 1
- 230000000885 phytotoxic effect Effects 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 239000002459 polyene antibiotic agent Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 241001446247 uncultured actinomycete Species 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
- B29C66/112—Single lapped joints
- B29C66/1122—Single lap to lap joints, i.e. overlap joints
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/40—General aspects of joining substantially flat articles, e.g. plates, sheets or web-like materials; Making flat seams in tubular or hollow articles; Joining single elements to substantially flat surfaces
- B29C66/41—Joining substantially flat articles ; Making flat seams in tubular or hollow articles
- B29C66/45—Joining of substantially the whole surface of the articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
- B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
-
- E—FIXED CONSTRUCTIONS
- E06—DOORS, WINDOWS, SHUTTERS, OR ROLLER BLINDS IN GENERAL; LADDERS
- E06B—FIXED OR MOVABLE CLOSURES FOR OPENINGS IN BUILDINGS, VEHICLES, FENCES OR LIKE ENCLOSURES IN GENERAL, e.g. DOORS, WINDOWS, BLINDS, GATES
- E06B5/00—Doors, windows, or like closures for special purposes; Border constructions therefor
- E06B5/10—Doors, windows, or like closures for special purposes; Border constructions therefor for protection against air-raid or other war-like action; for other protective purposes
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F41—WEAPONS
- F41H—ARMOUR; ARMOURED TURRETS; ARMOURED OR ARMED VEHICLES; MEANS OF ATTACK OR DEFENCE, e.g. CAMOUFLAGE, IN GENERAL
- F41H5/00—Armour; Armour plates
- F41H5/02—Plate construction
- F41H5/04—Plate construction composed of more than one layer
- F41H5/0407—Transparent bullet-proof laminatesinformative reference: layered products essentially comprising glass in general B32B17/06, e.g. B32B17/10009; manufacture or composition of glass, e.g. joining glass to glass C03; permanent multiple-glazing windows, e.g. with spacing therebetween, E06B3/66
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S428/00—Stock material or miscellaneous articles
- Y10S428/911—Penetration resistant layer
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Civil Engineering (AREA)
- Structural Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Securing Of Glass Panes Or The Like (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Joining Of Glass To Other Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT476668A AT288660B (de) | 1968-05-17 | 1968-05-17 | Schußsichere Verbundscheiben |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO123738B true NO123738B (hr) | 1972-01-03 |
Family
ID=3568072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO2016/69A NO123738B (hr) | 1968-05-17 | 1969-05-16 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3630814A (hr) |
| AT (1) | AT288660B (hr) |
| BE (1) | BE732910A (hr) |
| CH (1) | CH483554A (hr) |
| DE (1) | DE1802230A1 (hr) |
| FR (1) | FR2014131A1 (hr) |
| GB (1) | GB1223818A (hr) |
| NL (1) | NL6905833A (hr) |
| NO (1) | NO123738B (hr) |
| SE (1) | SE358466B (hr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3868805A (en) * | 1971-04-26 | 1975-03-04 | Usm Corp | Double glazing unit |
| US3872804A (en) * | 1971-09-21 | 1975-03-25 | Commercial Plastics & Supply C | Composite panel projectile barrier |
| SE370754B (hr) * | 1971-10-29 | 1974-10-28 | Emmaboda Glasverk Ab | |
| US3917891A (en) * | 1974-04-11 | 1975-11-04 | Asg Ind Inc | Fragmentation shield for impact resisting optical medium |
| US4027443A (en) * | 1975-10-14 | 1977-06-07 | Aneomstat Products Division, Dynamics Corporation Of America | Fire and impact resistant window assembly |
| US4058943A (en) * | 1976-06-03 | 1977-11-22 | Sturgill Lawrence W | Glass block panel |
| GB1589878A (en) * | 1976-11-26 | 1981-05-20 | Bfg Glassgroup | Method of manufacturing a hollow panel |
| US4316404A (en) * | 1978-06-30 | 1982-02-23 | Medlin Richard C | Lightweight armored vehicle and method of making same |
| US4242386A (en) * | 1978-11-28 | 1980-12-30 | Christel Konrad | Multiple glazing units |
| DE2856085C2 (de) * | 1978-12-23 | 1982-10-14 | Herbert 2000 Hamburg Mackenroth | Schußfeste Plattenanordnung für Sicherheitszwecke |
| US4312903A (en) * | 1980-03-05 | 1982-01-26 | General Electric Company | Impact resistant double glazed structure |
| FR2516646A1 (fr) * | 1981-11-18 | 1983-05-20 | Boussois Sa | Panneau anti-balles |
| DE3244152A1 (de) * | 1982-11-29 | 1984-05-30 | HPS-Hildebrandt Gesellschaft für Kunststoffverarbeitung mbH & Co KG, 3167 Burgdorf | Visier fuer einen beschusssicheren schutzhelm |
| DE8527571U1 (de) * | 1985-09-27 | 1986-01-02 | Körner, Lucy, 7012 Fellbach | Buch |
| DE9111130U1 (de) * | 1991-09-07 | 1992-01-16 | Trasco Export GmbH, 2820 Bremen | Kraftfahrzeug mit gepanzerter Scheibe |
| DE9114530U1 (de) * | 1991-11-22 | 1992-02-13 | Bosse GmbH & Co. KG, 4440 Rheine | Farbtonblock |
| SE470552B (sv) * | 1993-01-07 | 1994-08-22 | Jerzy Kryszof Johansson | Säkerhetsskåp |
| DE9310957U1 (de) * | 1993-07-22 | 1993-09-23 | Vegla Vereinigte Glaswerke Gmbh, 52066 Aachen | Panzerglasscheibe fuer kraftfahrzeuge |
| US5506051A (en) * | 1994-01-27 | 1996-04-09 | Nicolectronix Ltd. Laboratories | Transparent sheet composites for use as bullet-proof windows |
| GB9413180D0 (en) * | 1994-06-30 | 1994-08-24 | Glaverbel | Multiple glazing unit |
| US5636484A (en) * | 1994-08-11 | 1997-06-10 | Odl Incorporated | Hurricane door light |
| US6009790A (en) * | 1998-02-03 | 2000-01-04 | Tekorius; Paul | Single-use, bullet-proof shield |
| DE10148483A1 (de) * | 2001-10-01 | 2003-04-30 | Knorr Bremse Ag | Mobile Trennwand |
| US6546682B1 (en) | 2001-10-10 | 2003-04-15 | Odl, Incorporated | Hurricane door light |
| CN1795362B (zh) * | 2003-03-28 | 2012-09-05 | 艾伦-先锋公司 | 头部保护器 |
| US20050126091A1 (en) * | 2003-12-12 | 2005-06-16 | Kensington Windows, Inc. | Impact resistant glass unit |
| IL172883A (en) * | 2005-12-28 | 2011-10-31 | Daniel Besserglik | Compound protective glass |
| US8117790B2 (en) * | 2007-02-06 | 2012-02-21 | Vtech Patents Llc | Overmolded fenestration building product and method of manufacture |
| WO2009152220A2 (en) * | 2008-06-11 | 2009-12-17 | Madico, Inc. | Method of manufacturing an insulated, impact resistant window |
| WO2012135407A1 (en) | 2011-04-01 | 2012-10-04 | Am General Llc | Transparent armor structure |
| US10690451B2 (en) * | 2017-09-17 | 2020-06-23 | Kris McKenna | Transparent projectile-proof panes, devices and methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1988964A (en) * | 1932-07-15 | 1935-01-22 | Barrows Charles Storrs | Pane |
| US2741809A (en) * | 1952-03-28 | 1956-04-17 | Pittsburgh Plate Glass Co | Multiple glazed unit for test chambers |
| US3135645A (en) * | 1958-12-05 | 1964-06-02 | Goodyear Aerospace Corp | Laminates |
| FR1348328A (fr) * | 1963-02-26 | 1964-01-04 | Fenêtre composée à perméabilité réduite à la chaleur et au rayonnement, plus particulièrement pour le chauffage direct par l'énergie solaire des bâtiments et des serres | |
| US3179553A (en) * | 1963-03-12 | 1965-04-20 | Philip J Franklin | Lightweight armor plate |
| US3388034A (en) * | 1965-01-13 | 1968-06-11 | Mobay Chemical Corp | Laminated safety glass |
| US3406086A (en) * | 1965-03-31 | 1968-10-15 | Mobay Chemical Corp | Transparent safety laminates and method of making same |
| US3431818A (en) * | 1965-04-26 | 1969-03-11 | Aerojet General Co | Lightweight protective armor plate |
-
1968
- 1968-05-17 AT AT476668A patent/AT288660B/de not_active IP Right Cessation
- 1968-10-10 DE DE19681802230 patent/DE1802230A1/de active Pending
-
1969
- 1969-04-16 NL NL6905833A patent/NL6905833A/xx unknown
- 1969-04-17 GB GB09600/69A patent/GB1223818A/en not_active Expired
- 1969-04-18 CH CH586069A patent/CH483554A/de not_active IP Right Cessation
- 1969-04-25 US US819405A patent/US3630814A/en not_active Expired - Lifetime
- 1969-05-12 BE BE732910D patent/BE732910A/xx not_active IP Right Cessation
- 1969-05-13 SE SE06828/69A patent/SE358466B/xx unknown
- 1969-05-13 FR FR6915418A patent/FR2014131A1/fr not_active Withdrawn
- 1969-05-16 NO NO2016/69A patent/NO123738B/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT288660B (de) | 1971-03-10 |
| SE358466B (hr) | 1973-07-30 |
| NL6905833A (hr) | 1969-11-19 |
| BE732910A (hr) | 1969-10-16 |
| DE1802230A1 (de) | 1970-02-12 |
| US3630814A (en) | 1971-12-28 |
| FR2014131A1 (hr) | 1970-04-17 |
| CH483554A (de) | 1969-12-31 |
| GB1223818A (en) | 1971-03-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO123738B (hr) | ||
| US3892850A (en) | Pimaricin and process of producing same | |
| SU1082304A3 (ru) | Способ получени белковых пищевых продуктов | |
| US4032663A (en) | Process for using cell wall-lysing enzymes | |
| CN111925945A (zh) | 一株烟管菌g14及应用 | |
| CN1219879C (zh) | 淡紫灰链霉菌海南变种及由该菌种制备农用抗生素的方法 | |
| CN1970731A (zh) | 利用黑曲霉制备高效生物铁载体的方法 | |
| DE2939269C2 (de) | Verfahren zur optischen Trennung von DL-2-Amino-4-hydroxy(methyl)phosphinoylbuttersäure | |
| US3870600A (en) | Selective and enrichment medium for the isolation identification and propagation of yeasts and fungi | |
| WO1999050434A1 (en) | Strain of the microorganism penicillium oxalicum var. armeniaca and its application | |
| CN111471721A (zh) | 一种芸薹链格孢菌代谢物在制备黄曲霉菌抑菌剂中的应用 | |
| US3969189A (en) | Cell wall-lysing complex enzymes and a process for the production thereof | |
| CN111979157B (zh) | 一种马铃薯干腐病拮抗菌jz3-1-15及其应用 | |
| CN110564628B (zh) | 一种全营养基质微生物培养方法 | |
| US2689854A (en) | Acetopyrrothine and preparation thereof | |
| CN114790438A (zh) | 一种提高牛樟芝胞外多糖产量及其抗氧化性的方法 | |
| US2805185A (en) | Antibiotic and production thereof | |
| Wolf | CITRUS CANKER¹ | |
| CN112877218A (zh) | 牛樟芝子实体栽培及其应用 | |
| JP2003102429A (ja) | レモン発酵物及びその製造方法 | |
| SU503532A3 (ru) | Способ получени фермента дл лизиса клеток микроорганизмов | |
| US2972569A (en) | Hortesin, an antifungal agent derived from streptomyces versipellis | |
| US3058890A (en) | Process for the preparation of pectolytic enzymes | |
| NO119308B (hr) | ||
| CN117305135A (zh) | 一株拟康氏木霉t0027及其在防治猕猴桃软腐病中的应用 |