NL950006I2 - Gesubstitueerde aromatische sulfonamiden als antiglaucoommiddelen. - Google Patents

Gesubstitueerde aromatische sulfonamiden als antiglaucoommiddelen.

Info

Publication number
NL950006I2
NL950006I2 NL950006C NL950006C NL950006I2 NL 950006 I2 NL950006 I2 NL 950006I2 NL 950006 C NL950006 C NL 950006C NL 950006 C NL950006 C NL 950006C NL 950006 I2 NL950006 I2 NL 950006I2
Authority
NL
Netherlands
Prior art keywords
substituted aromatic
aromatic sulfonamides
glaucoma agents
sulfonamides
glaucoma
Prior art date
Application number
NL950006C
Other languages
English (en)
Dutch (nl)
Other versions
NL950006I1 (nl
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26747752&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL950006(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/067,326 external-priority patent/US4797413A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL950006I1 publication Critical patent/NL950006I1/nl
Publication of NL950006I2 publication Critical patent/NL950006I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Lubricants (AREA)
  • Photosensitive Polymer And Photoresist Processing (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Dental Preparations (AREA)
NL950006C 1987-06-26 1995-04-27 Gesubstitueerde aromatische sulfonamiden als antiglaucoommiddelen. NL950006I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/067,326 US4797413A (en) 1986-05-14 1987-06-26 Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use
US07/208,314 US4863922A (en) 1984-12-12 1988-06-15 Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use

Publications (2)

Publication Number Publication Date
NL950006I1 NL950006I1 (nl) 1995-06-16
NL950006I2 true NL950006I2 (nl) 1997-02-03

Family

ID=26747752

Family Applications (1)

Application Number Title Priority Date Filing Date
NL950006C NL950006I2 (nl) 1987-06-26 1995-04-27 Gesubstitueerde aromatische sulfonamiden als antiglaucoommiddelen.

Country Status (18)

Country Link
US (1) US4863922A (cg-RX-API-DMAC10.html)
EP (1) EP0296879B1 (cg-RX-API-DMAC10.html)
JP (1) JPH0631247B2 (cg-RX-API-DMAC10.html)
AT (1) ATE86998T1 (cg-RX-API-DMAC10.html)
AU (1) AU616664B2 (cg-RX-API-DMAC10.html)
CA (2) CA1328262C (cg-RX-API-DMAC10.html)
CY (1) CY1772A (cg-RX-API-DMAC10.html)
DE (2) DE3879292T2 (cg-RX-API-DMAC10.html)
DK (1) DK167684B1 (cg-RX-API-DMAC10.html)
ES (1) ES2053738T4 (cg-RX-API-DMAC10.html)
GR (1) GR3007407T3 (cg-RX-API-DMAC10.html)
IE (1) IE62255B1 (cg-RX-API-DMAC10.html)
IL (1) IL86822A (cg-RX-API-DMAC10.html)
LU (1) LU88633I2 (cg-RX-API-DMAC10.html)
NL (1) NL950006I2 (cg-RX-API-DMAC10.html)
NZ (1) NZ225166A (cg-RX-API-DMAC10.html)
PT (1) PT87832B (cg-RX-API-DMAC10.html)
SG (1) SG24394G (cg-RX-API-DMAC10.html)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1320487C (en) * 1987-08-03 1993-07-20 George D. Hartman Substituted thieno[2,3-.beta.]thiophene-2-sulfonamides as antiglaucoma agents
US5260453A (en) * 1988-09-23 1993-11-09 Ortho Pharmaceutical Corporation Substituted thienopyrans as antihypertensive agents
US4876271A (en) * 1988-12-20 1989-10-24 Merck & Co., Inc. Substituted thieno[3,2-b]thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors
US4929549A (en) * 1989-02-08 1990-05-29 Merck & Co., Inc. 5-carbamoylthieno[2,3-b]thiophene-2-sulfon-amides as topically active carbonic anhydrase inhibitors
US4946859A (en) * 1989-07-31 1990-08-07 Merck & Co., Inc. 4-(2-methyl-2-hydroxypropylamino)-5,6-dihydrothieno-[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide
US5120757A (en) * 1989-07-31 1992-06-09 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents
CA2028496A1 (en) * 1989-10-31 1991-05-01 Tohru Nakao Thiophene compounds and their pharmaceutical uses
US5045561A (en) * 1990-04-12 1991-09-03 Merck & Co., Inc. Substituted furan sulfonamides as antiglaucoma agents
IE911192A1 (en) * 1990-04-12 1991-10-23 Merck & Co Inc Substituted aromatic sulfonamides as antiglaucoma agents
JP3031498B2 (ja) * 1990-04-12 2000-04-10 メルク エンド カムパニー インコーポレーテッド 抗緑内障剤としての置換芳香族スルホンアミド類
US5157129A (en) * 1990-04-18 1992-10-20 Merck & Co., Inc. Enantiospecific synthesis of s-(+)-5,6-dihydro-4-(r-amino)-4h-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide
US5091409A (en) * 1990-05-17 1992-02-25 Merck & Co., Inc. 4-alkylamino-6-(C3-5 -hydrocarbyl)thieno[2,3-B]thiopyran-2-sulfonamide-7,7-dioxides
US5093332A (en) * 1990-10-01 1992-03-03 Merck & Co., Inc. Substituted thieno(2,3-b)(1,4)thiazine-6-sulfonamides as antiglaucoma agents
EP0480745A3 (en) * 1990-10-12 1992-07-29 Merck & Co. Inc. Substituted dihydrothieno-thiophene-2-sulfonamides and dioxides thereof
US5216020A (en) * 1990-10-12 1993-06-01 Merck & Co., Inc. Substituted 4,5-dihydrothieno(2,3-b)thiophene-2-sulfonamides and 6,6-dioxides thereof
WO1992018124A1 (en) * 1991-04-17 1992-10-29 Merck & Co., Inc. OPHTHALMIC COMPOSITIONS COMPRISING COMBINATIONS OF A CARBONIC ANHYDRASE INHIBITOR AND A β-ADRENERGIC ANTAGONIST
SG84487A1 (en) 1991-04-17 2001-11-20 Merck & Co Inc Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a b-adrenergic antagonist
CA2080403A1 (en) * 1991-10-15 1993-04-16 John J. Baldwin Tricyclic thienothiopyrans
US5932572A (en) * 1992-02-21 1999-08-03 Alcon Laboratories, Inc. Topical anti-glaucoma compositions
DE69320329T2 (de) * 1992-02-21 1998-12-24 Alcon Laboratories, Inc., Fort Worth, Tex. Topische Antiglaukoma Zusammensetzungen, enthaltend Karbonhydrasehemmer und Beta-Blocker
JP3333206B2 (ja) * 1992-08-28 2002-10-15 アベシア・リミテッド 不斉還元方法
JP3279671B2 (ja) * 1992-09-28 2002-04-30 鐘淵化学工業株式会社 チエノチオピラン誘導体の製造方法
TW265343B (cg-RX-API-DMAC10.html) * 1993-03-22 1995-12-11 Merck & Co Inc
US6316443B1 (en) 1994-08-04 2001-11-13 Merck & Co., Inc. Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a β-adrenergic antagonist
TW438587B (en) * 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
FR2754712B1 (fr) 1996-10-17 1999-09-03 Merck Sharp Dohme Chibret Lab Compositions ophtalmiques
TWI290470B (en) 1999-12-01 2007-12-01 Sankyo Co The composition for treating glaucoma
US6548535B2 (en) 2000-01-18 2003-04-15 Merck & Co., Inc. Method for treating ocular hypertension
JP2003520245A (ja) * 2000-01-18 2003-07-02 メルク エンド カムパニー インコーポレーテッド 高眼圧症を治療するための眼科組成物
ES2177415B1 (es) * 2000-09-04 2004-10-16 Ragactives, S.L. Procedimiento para la obtencion de 4-alquilamino-5, 6-dihidro-4h-tieno-(2,3b)-tiopiran-2-sulfonamida-7-dioxidos, e intermedios.
US20040254230A1 (en) * 2001-12-03 2004-12-16 Ogidigben Miller J. Method for treating ocular hypertension
WO2003077845A2 (en) * 2002-03-15 2003-09-25 Merck & Co., Inc. Compositions and methods for treating glaucoma and ocular hypertension
AU2003233731A1 (en) * 2002-06-06 2003-12-22 Xavier Billot 1,5-disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases
CA2488802A1 (en) * 2002-06-14 2003-12-24 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
EP1515730A4 (en) * 2002-06-17 2005-07-20 Merck & Co Inc NEW MAXI-K CHANNEL BLOCKS, USE METHOD AND METHOD FOR THE PRODUCTION THEREOF
EP1515974A4 (en) * 2002-06-17 2007-02-28 Merck & Co Inc NEW MAXI-K CHANNEL BLOCKS, METHOD OF USE AND METHOD FOR THE PRODUCTION THEREOF
JP2005532361A (ja) * 2002-06-17 2005-10-27 メルク　エンド　カムパニー　インコーポレーテッド 高眼圧症の治療用の眼科用組成物
US7109223B2 (en) * 2002-08-28 2006-09-19 Merck & Co. Inc. Oxazolidin-2-one and thiazolidin-2-one derivatives for use as EP4 receptor agonists in the treatment of glaucoma
JP2006505572A (ja) * 2002-10-25 2006-02-16 メルク フロスト カナダ アンド カンパニー Ｅｐ４受容体アゴニストとしての２−ピロリドン
JP2006524239A (ja) * 2003-03-27 2006-10-26 メルク　エンド　カムパニー　インコーポレーテッド 高眼圧症を治療するための眼用組成物
WO2006068333A1 (en) 2004-12-20 2006-06-29 Sk Corporation Method for separating of optically pure thiophene compounds using simulated moving bed chromatography
WO2006070387A1 (en) * 2004-12-28 2006-07-06 Council Of Scientific And Industrial Research PROCESS FOR PREPARING 5,6-DIHYDRO-4-(S)-(ETHYLAMINO)-6-(S) METHYL-4H-THIENO[2,3b]THIOPYRAN-2-SULPHONAMIDE-7,7-DIOXIDE HCI
US7109353B2 (en) * 2004-12-28 2006-09-19 Council Of Scientific And Industrial Research Process for preparing 5,6-dihydro-4-(S)-(ethylamino)-6-(S) methyl-4H-thieno[2,3b]thiopyran-2-sulphonamide-7,7-dioxide HCl
DE602007001885D1 (de) * 2006-04-21 2009-09-17 Zach System Spa Verfahren zur herstellung von dorzolamid
EP1918293A1 (en) * 2006-10-02 2008-05-07 Sandoz AG Process for the preparation of 6-substituted-4-oxo-thieno [2,3b]thiopyran-2-sulfonic acid
JP5313125B2 (ja) 2007-02-28 2013-10-09 旭化成ファーマ株式会社 スルホンアミド誘導体
AU2008247144B2 (en) * 2007-05-07 2013-02-28 Cipla Limited Process for preparing dorzolamide
US20110015158A1 (en) 2007-12-11 2011-01-20 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
WO2010061398A1 (en) * 2008-11-27 2010-06-03 Suven Life Sciences Limited Process for preparing dorzolamide hydrochloride and its intermediate
EP2683724B1 (en) 2011-03-10 2015-05-06 ZaCh System S.p.A. Asymmetric reduction process
ITMI20121165A1 (it) * 2012-07-03 2014-01-04 Zach System Spa Processo di riduzione asimmetrica
CN103497202B (zh) * 2013-10-23 2015-12-02 武汉武药科技有限公司 盐酸多佐胺中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4416890A (en) * 1981-07-13 1983-11-22 Merck & Co., Inc. Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4386098A (en) * 1981-11-03 1983-05-31 Merck & Co., Inc. 6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure
US4426388A (en) * 1982-04-02 1984-01-17 Merck & Co., Inc. 5-Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4499103A (en) * 1983-03-17 1985-02-12 Merck & Co., Inc. Benzothiazole-2-sulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4677115A (en) * 1984-12-12 1987-06-30 Merck & Co., Inc. Antiglaucoma thieno-thiopyran and thieno-thiepin sulfonamide derivatives, compositions, and method of use thereof
DE3568431D1 (en) * 1984-12-12 1989-04-06 Merck & Co Inc Substituted aromatic sulfonamides, their preparation and ophthalmic compositions containing them
US4731368A (en) * 1986-12-08 1988-03-15 Merck & Co., Inc. Thienopyridine sulfonamides and their ophthalmological formulation

Also Published As

Publication number Publication date
US4863922A (en) 1989-09-05
AU1838788A (en) 1989-01-05
ES2053738T4 (es) 2011-12-29
IL86822A0 (en) 1988-11-30
SG24394G (en) 1994-06-10
NZ225166A (en) 1991-05-28
DK167684B1 (da) 1993-12-06
JPH0631247B2 (ja) 1994-04-27
PT87832A (pt) 1989-05-31
DE19575017I2 (de) 2008-11-20
CY1772A (en) 1995-10-20
IE881933L (en) 1988-12-26
IL86822A (en) 1992-01-15
EP0296879B1 (en) 1993-03-17
DK348588A (da) 1989-02-24
JPH01100174A (ja) 1989-04-18
DE3879292D1 (de) 1993-04-22
DK348588D0 (da) 1988-06-24
EP0296879A1 (en) 1988-12-28
AU616664B2 (en) 1991-11-07
NL950006I1 (nl) 1995-06-16
LU88633I2 (fr) 1995-09-01
IE62255B1 (en) 1995-01-11
GR3007407T3 (cg-RX-API-DMAC10.html) 1993-07-30
ES2053738T3 (es) 1994-08-01
PT87832B (pt) 1992-10-30
CA1329211C (en) 1994-05-03
DE3879292T2 (de) 1993-09-09
CA1328262C (en) 1994-04-05
ATE86998T1 (de) 1993-04-15

Similar Documents

Publication Publication Date Title
NL950006I1 (nl) Gesubstitueerde aromatische sulfonamiden als antiglaucoom-middelen.
IE853143L (en) Aromatic sulfonamides, antiglaucoma agents
DK172089D0 (da) 1,3-dioxolanderivater samt fremgangsmaade til fremstilling deraf
NL300098I1 (nl) Thiophene sulfonamides useful as carbonic anhydrase inhibitors.
DE3852110D1 (de) Gerät zum Insufflieren von Gas in eine Körperhöhle.
ATE196466T1 (de) Inhibitoren retroviraler proteasen
PT87620A (pt) Process for preparing thiophene sulfonamide antiglaucoma agents
ATE109465T1 (de) 4-aryl-4-piperidine (oder -pyrrolidin- oder - hexahydroazepin-) carbinole und heterocyclische analoga davon.
ATE98647T1 (de) Substituierte thieno(2,3-b) thiophen-2sulfonamide als mittel gegen glaukoma.
DE3876221D1 (de) Absorption von schwefelwasserstoff.
ES2044100T4 (es) Ciertas combinaciones de antagonistas del "paf" y antihistaminicos y metodos.
DE69023459D1 (de) Behandlung von pulmonarer Disfunktion mit 15-Keto-prostaglandin-Derivaten.
MX169432B (es) Metodo para tratar lentes de contacto
ES491921A0 (es) Procedimiento para preparar agentes para el tratamiento de fibras queratinicas
DK0458537T3 (da) Anvendelse af en terapeutisk forbindelse til behandling af bronkitis
DK435089D0 (da) Anvendelse af zofenopril til behandling af rheumatoid arthritis
ES8506668A1 (es) Procedimiento de preparacion de nuevas sales de dioxido de benzotiacina.
IT1115835B (it) Capsula per bottiglie gia' tappate
SE8701177L (sv) Arbetsmoebel med staellbart stativ