NL94112C - - Google Patents

Info

Publication number
NL94112C
NL94112C NL179985A NL179985A NL94112C NL 94112 C NL94112 C NL 94112C NL 179985 A NL179985 A NL 179985A NL 179985 A NL179985 A NL 179985A NL 94112 C NL94112 C NL 94112C
Authority
NL
Netherlands
Application number
NL179985A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22345996&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL94112(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Application granted granted Critical
Publication of NL94112C publication Critical patent/NL94112C/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G01N15/13—Details pertaining to apertures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NL179985A 1949-08-27 1953-07-18 NL94112C (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US112819A US2656508A (en) 1949-08-27 1949-08-27 Means for counting particles suspended in a fluid

Publications (1)

Publication Number Publication Date
NL94112C true NL94112C (xx) 1960-05-16

Family

ID=22345996

Family Applications (1)

Application Number Title Priority Date Filing Date
NL179985A NL94112C (xx) 1949-08-27 1953-07-18

Country Status (5)

Country Link
US (1) US2656508A (xx)
DE (1) DE964810C (xx)
FR (1) FR1080716A (xx)
GB (1) GB722418A (xx)
NL (1) NL94112C (xx)

Families Citing this family (295)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2709781A (en) * 1952-06-20 1955-05-31 American Chem Paint Co Instrument for determining the electrical conductance of liquids
US2836792A (en) * 1956-01-30 1958-05-27 Gen Electric Dielectric testing device
BE562451A (xx) * 1956-05-09
NL236797A (xx) * 1958-03-06
US3233173A (en) * 1958-04-28 1966-02-01 United Res Inc Method of determining the volume of particles in a mixture
NL240601A (xx) * 1958-12-29
US3015775A (en) * 1959-01-09 1962-01-02 Coulter Electronics Fluid metering system and apparatus
US3259842A (en) * 1959-08-19 1966-07-05 Coulter Electronics Particle analyzing device
US3083909A (en) * 1960-04-05 1963-04-02 New Brunswick Scientific Co Bacteria-counting apparatus
US3057758A (en) * 1960-10-26 1962-10-09 Harry H Walker System for measuring and increasing flow through pipelines
US3160785A (en) * 1961-01-26 1964-12-08 Exxon Research Engineering Co Process of reducing electrostatic charges in fluid flow lines
US3141113A (en) * 1961-01-26 1964-07-14 Exxon Research Engineering Co Process of controlling electrostatic charges
DE1698203B2 (de) * 1961-04-06 1973-04-19 Amplitudendiskriminator fuer ein teilchenanalysiergeraet
US3165692A (en) * 1961-05-15 1965-01-12 Technicon Instr Continuously operable apparatus and method for counting particles in successive portions of a flowing fluid stream
DE1292877B (de) * 1961-06-23 1969-04-17 Cap Ges Fuer Entwicklung Von M Verfahren und Vorrichtung zum selbsttaetigen photoelektrischen Zaehlen, Registrierenund Differenzieren von Teilchen
GB980206A (en) * 1961-09-20 1965-01-13 Coulter Electronics Improvements in and relating to apparatus for studying the physical properties of particles
GB1042144A (en) * 1961-11-10 1966-09-14 Atomic Energy Authority Uk Apparatus for indicating the metal oxide content of a liquid metal
US3264557A (en) * 1961-12-06 1966-08-02 Heeps Brian Hamilton Method and apparatus for detecting and measuring minute quantities of water presentin liquid hydrocarbon fuels
US3286167A (en) * 1962-04-25 1966-11-15 Shell Oil Co Monitoring of heterogeneity of alkylation emulsions
US3220777A (en) * 1962-09-20 1965-11-30 Allis Chalmers Mfg Co Head control for particle counter
US3287638A (en) * 1962-10-02 1966-11-22 Univ Iowa State Res Found Inc Method of counting erythrocytes utilizing high frequency current
DE1498642B1 (de) * 1963-07-13 1971-08-26 Coulter Electronics Vorrichtung zur untersuchung von in einer elektrisch leiten den fluessigkeit sispendierten teilchen insbesondere von blutkoerperchen
US3324720A (en) * 1963-07-29 1967-06-13 Friends Of Psychiatric Res Inc Apparatus and method for determining rate of flow by measurement of electrical property of stream
NL137000C (xx) * 1964-03-26
US3395343A (en) * 1964-07-21 1968-07-30 Coulter Electronics Electronic particle study apparatus and vessel construction therefor
US3345502A (en) * 1964-08-14 1967-10-03 Robert H Berg Pulse analyzer computer
US3289916A (en) * 1964-11-16 1966-12-06 Coulter Electronics Variable pressure pump for manometric metering device
US3502972A (en) * 1965-03-08 1970-03-24 Robert H Berg Continuous flow particle size analyser apparatus having suspension level maintaining means
US3380584A (en) * 1965-06-04 1968-04-30 Atomic Energy Commission Usa Particle separator
US3444464A (en) * 1965-11-26 1969-05-13 Coulter Electronics Multiple aperture fittings for particle analyzing apparatus
US3369984A (en) * 1966-03-04 1968-02-20 Dow Chemical Co Control apparatus
US3479884A (en) * 1967-08-15 1969-11-25 Paul Imris Method and apparatus for measuring specific surface area of powders
US3810010A (en) * 1968-11-02 1974-05-07 Telefunken Patent Particle analysis method and apparatus wherein liquid containing particles is sucked into a constricted flow path
US3993948A (en) * 1969-12-15 1976-11-23 Coulter Electronics, Inc. Particle analyzer having scanning apparatus series coupled between a d.c. power source and the parallel connection of a d.c. short-circuiting device and a voltage sensitive signal detector
DE2219778C3 (de) * 1972-04-22 1981-10-29 Coulter Electronics, Inc., 33010 Hialeah, Fla. Verfahren zur Ermittlung physiologischer Eigenschaften nativer Blutzellen und Anordnung zur Durchführung des Verfahrens
US3768084A (en) * 1972-07-14 1973-10-23 Becton Dickinson Co Particle counter having a clog and bubble alarm
US3973194A (en) * 1972-08-07 1976-08-03 Becton, Dickinson And Company Particle counter
US3984307A (en) * 1973-03-05 1976-10-05 Bio/Physics Systems, Inc. Combined particle sorter and segregation indicator
US3944917A (en) * 1973-08-13 1976-03-16 Coulter Electronics, Inc. Electrical sensing circuitry for particle analyzing device
US3961249A (en) * 1973-10-15 1976-06-01 Coulter Electronics, Inc. Particle size distribution analyzation employing trailing edge differentiation
US3976429A (en) * 1973-10-16 1976-08-24 Coulter Electronics, Inc. Backwash system for diluting apparatus
DE2428082C3 (de) * 1974-06-11 1979-05-17 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Schaltangsanordnung zur Eichung einer Meßanordnung zur Volumen-Messung von Partikeln
US3921006A (en) * 1974-09-16 1975-11-18 Coulter Electronics Particle counting apparatus including isolated manometer
US4130754A (en) * 1977-06-16 1978-12-19 Cortex Research Corporation Particle counting
US4244513A (en) * 1978-09-15 1981-01-13 Coulter Corporation Centrifuge unit
US4293221A (en) * 1979-04-17 1981-10-06 Research Corporation Multidimensional slit-scan flow system
US4263508A (en) * 1979-04-20 1981-04-21 Research Corporation Pulse edge measurement for determining particle dimensional characteristics
US4240029A (en) * 1979-04-20 1980-12-16 Becton Dickinson & Company Apparatus for counting particles in a liquid suspension
US4299726A (en) * 1979-05-07 1981-11-10 Coulter Electronics, Inc. Process for preparing whole blood reference controls having long term stability, preconditioning diluent and media therefor
US4298836A (en) * 1979-11-23 1981-11-03 Coulter Electronics, Inc. Particle shape determination
US4278936A (en) * 1980-02-05 1981-07-14 Coulter Electronics, Inc. Biological cell parameter change test method and apparatus
US4453266A (en) * 1980-04-21 1984-06-05 Rush-Presbyterian-St. Luke's Medical Center Method and apparatus for measuring mean cell volume of red blood cells
US4350892A (en) * 1980-07-31 1982-09-21 Research Corporation X'-, Y'-, Z'- axis multidimensional slit-scan flow system
US4395676A (en) * 1980-11-24 1983-07-26 Coulter Electronics, Inc. Focused aperture module
US4472506A (en) * 1981-01-13 1984-09-18 Liburdy Robert P Method for determining cell membrane dielectric breakdown
US4368423A (en) * 1981-01-13 1983-01-11 Liburdy Robert P Apparatus for determining cell membrane dielectric breakdown
US4374644A (en) * 1981-04-06 1983-02-22 Coulter Electronics, Inc. Blood cell volume monitoring
US4580096A (en) * 1981-07-06 1986-04-01 Coulter Electronics, Inc. Isotachophoresis analyzer for inductively detecting boundaries between adjoining substances having different conductivities
US4535284A (en) * 1981-07-10 1985-08-13 Coulter Electronics, Inc. High and low frequency analysis of osmotic stress of cells
JPS5829450A (ja) * 1981-08-18 1983-02-21 株式会社豊田中央研究所 ヘマトクリツト測定装置
US4484134A (en) * 1981-08-31 1984-11-20 Coulter Electrnonics, Inc. Elongate particle sensing aperture
US4450435A (en) * 1981-11-30 1984-05-22 Bobby Dencil James Analog debris alarm
US4515274A (en) * 1981-12-02 1985-05-07 Coulter Corporation Particle analyzing and sorting apparatus
US4510438A (en) * 1982-02-16 1985-04-09 Coulter Electronics, Inc. Coincidence correction in particle analysis system
US4527114A (en) * 1982-02-25 1985-07-02 Coulter Electronics, Inc. Electrical slit scanning apparatus
DE3233055C2 (de) * 1982-09-06 1994-07-28 Coulter Electronics Durchflußvorrichtung zur Untersuchung einzelner, in einer Flüssigkeit suspendierter Teilchen
US4555662A (en) * 1983-03-03 1985-11-26 Limca Research Inc. Method and apparatus for the detection and measurement of particulates in molten metal
US4633169A (en) * 1983-07-08 1986-12-30 Kontron Holding Ag Blood particle analyzer
US4710021A (en) * 1983-10-14 1987-12-01 Sequoia-Turner Corporation Particulate matter analyzing apparatus and method
US4704364A (en) * 1984-05-18 1987-11-03 Coulter Electronics, Inc. Hematology control compositions for three populations of leukocytes; and methods for their preparation and use in whole blood control systems
US4751179A (en) * 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
JPS61124850A (ja) * 1984-11-21 1986-06-12 Eruma Kogaku Kk 超純水の不純物測定装置
GB2177804A (en) * 1985-05-31 1987-01-28 Coulter Electronics Analysing and editing electrical pulses
US4791355A (en) * 1986-10-21 1988-12-13 Coulter Electronics Inc. Particle analyzer for measuring the resistance and reactance of a particle
KR970007077B1 (ko) * 1987-03-13 1997-05-02 코울터 일렉트로닉스 인커퍼레이티드 광산란 기술을 이용한 다중-부분식별 분석 방법
US5389549A (en) * 1987-05-29 1995-02-14 Toa Medical Electronics Co., Ltd. Method for classifying leukocytes and a reagent used therefor
JPH02170053A (ja) * 1988-12-23 1990-06-29 Meiji Seika Kaisha Ltd 微生物の検出方法及び装置
US4957008A (en) * 1988-12-28 1990-09-18 Coulter Electronics, Inc. Fluid sampling and transfer valve assembly
JP2815435B2 (ja) * 1989-12-22 1998-10-27 株式会社日立製作所 粒子解析装置及び血球カウンタ
DK111990D0 (da) * 1990-05-04 1990-05-04 Biometic Aps Apparat og fremgangsmaade til analyse af en vaeskesuspension
US5194909A (en) * 1990-12-04 1993-03-16 Tycko Daniel H Apparatus and method for measuring volume and hemoglobin concentration of red blood cells
US5158751A (en) * 1990-12-13 1992-10-27 Coulter Corporation Liquid metering and transfer valve assembly
ATE193603T1 (de) * 1992-02-24 2000-06-15 Coulter Corp Suspensionsmedien für hämatoligische zusammensetzungen und methode für ihren gebrauch
US6362003B1 (en) 1992-02-24 2002-03-26 Coulter Corporation Hematological reference control composition containing leukocyte analogs, methods of making, and uses thereof
US6509192B1 (en) 1992-02-24 2003-01-21 Coulter International Corp. Quality control method
BR9305952A (pt) * 1992-02-24 1997-10-21 Coulter Corp Produto de controle de hematologia processo para utilizar o mesmo e processo para fabricação de análogos de leucócito
GB9215733D0 (en) * 1992-07-24 1992-09-09 British Tech Group Method of and apparatus for determining a property of a sample
US5395588A (en) * 1992-12-14 1995-03-07 Becton Dickinson And Company Control of flow cytometer having vacuum fluidics
IL106662A (en) * 1993-08-11 1996-10-31 Yissum Res Dev Co Install a flow cell to monitor blood or any single cell suspension under flow
GB9405028D0 (en) * 1994-03-15 1994-04-27 Counting Tech Ltd Fluid diluter
US5895869A (en) * 1995-11-17 1999-04-20 Mwi, Inc. Method and apparatus for analyzing particulate matter
US5817518A (en) * 1995-12-18 1998-10-06 Coulter International Corp. Reagent and method for differential determination of leukocytes in blood
JP3276550B2 (ja) * 1995-12-19 2002-04-22 シスメックス株式会社 試料定量装置
US5686309A (en) * 1996-01-19 1997-11-11 Coulter International Corp. Method and apparatus for determination of hemoglobin content of individual red blood cells
US6221654B1 (en) 1996-09-25 2001-04-24 California Institute Of Technology Method and apparatus for analysis and sorting of polynucleotides based on size
WO1998017383A1 (en) 1996-10-21 1998-04-30 Smithkline Beecham Plc Apparatus and method for distributing beads
GB2337598B (en) * 1996-11-20 2000-08-16 Microbial Systems Ltd Particle sizing apparatus
GB9624096D0 (en) * 1996-11-20 1997-01-08 Microbial Systems Ltd Apparatus and method of use thereof
US6418802B1 (en) * 1996-11-21 2002-07-16 Michael Anthony Wood Particle sizing apparatus and method of use thereof
US5882934A (en) * 1997-01-21 1999-03-16 Coulter International Corp. Composition and method for hemoglobin and cell analysis
US6175227B1 (en) 1997-07-03 2001-01-16 Coulter International Corp. Potential-sensing method and apparatus for sensing and characterizing particles by the Coulter principle
US6111398A (en) * 1997-07-03 2000-08-29 Coulter International Corp. Method and apparatus for sensing and characterizing particles
US6833242B2 (en) * 1997-09-23 2004-12-21 California Institute Of Technology Methods for detecting and sorting polynucleotides based on size
US6540895B1 (en) 1997-09-23 2003-04-01 California Institute Of Technology Microfabricated cell sorter for chemical and biological materials
US7214298B2 (en) * 1997-09-23 2007-05-08 California Institute Of Technology Microfabricated cell sorter
US6122599A (en) * 1998-02-13 2000-09-19 Mehta; Shailesh Apparatus and method for analyzing particles
US5994139A (en) * 1998-04-07 1999-11-30 Coulter International Corp. Stable hematology control composition and method of use
US6507400B1 (en) 1999-02-27 2003-01-14 Mwi, Inc. Optical system for multi-part differential particle discrimination and an apparatus using the same
US6259242B1 (en) 1999-05-26 2001-07-10 Coulter International Corp. Apparatus incorporating a sensing conduit in conductive material and method of use thereof for sensing and characterizing particles
CA2381285C (en) * 1999-08-06 2010-04-27 Ulrik Darling Larsen Particle characterisation apparatus
US6232125B1 (en) 1999-08-09 2001-05-15 Coulter International Corp. Method and apparatus for differentiating and enumerating leukocytes
US6587792B1 (en) * 2000-01-11 2003-07-01 Richard A. Thomas Nuclear packing efficiency
US6646742B1 (en) 2000-02-19 2003-11-11 Mwi, Inc. Optical device and method for multi-angle laser light scatter
WO2001067369A2 (en) * 2000-03-03 2001-09-13 California Institute Of Technology Combinatorial array for nucleic acid analysis
US6624621B2 (en) 2000-04-03 2003-09-23 Howard L. North, Jr. Particle counter volume sensor
US6363801B1 (en) * 2000-04-26 2002-04-02 General Electric Company Apparatus and process for selecting and positioning particles
US6514763B2 (en) 2000-04-28 2003-02-04 Hematronix, Inc. Hematology blood control and method for preparation of same
US7351376B1 (en) 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
US7062418B2 (en) 2000-06-27 2006-06-13 Fluidigm Corporation Computer aided design method and system for developing a microfluidic system
WO2002023163A1 (en) 2000-09-15 2002-03-21 California Institute Of Technology Microfabricated crossflow devices and methods
WO2002030486A2 (en) 2000-10-13 2002-04-18 Fluidigm Corporation Microfluidic device based sample injection system for analytical devices
US7049093B2 (en) * 2000-11-08 2006-05-23 Sysmex Corporation Method of classifying and counting nucleated bone marrow cells
US20050196785A1 (en) * 2001-03-05 2005-09-08 California Institute Of Technology Combinational array for nucleic acid analysis
US6960437B2 (en) 2001-04-06 2005-11-01 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
US6916658B2 (en) * 2001-07-27 2005-07-12 Beckman Coulter, Inc. Method for measurement of immature granulocytes
US6472215B1 (en) 2001-07-27 2002-10-29 Coulter International Corp. Method of analyzing nucleated red blood cells in a blood sample
US6410330B1 (en) 2001-07-27 2002-06-25 Coulter International Corp. Method for measurement of nucleated red blood cells
JP2005506525A (ja) 2001-07-27 2005-03-03 ベックマン コールター，インコーポレーテッド 有核赤血球の計測法の方法
US8440093B1 (en) 2001-10-26 2013-05-14 Fuidigm Corporation Methods and devices for electronic and magnetic sensing of the contents of microfluidic flow channels
EP1463796B1 (en) 2001-11-30 2013-01-09 Fluidigm Corporation Microfluidic device and methods of using same
US7691333B2 (en) 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
WO2003085379A2 (en) 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
US6709868B2 (en) * 2002-05-20 2004-03-23 Portascience Inc. Method and apparatus for measuring white blood cell count
EP1530710B1 (en) * 2002-06-11 2017-08-09 Koninklijke Philips N.V. A disposable cartridge for characterizing particles suspended in a liquid
US20040090613A1 (en) * 2002-07-17 2004-05-13 Goix Philippe J. Method for measuring the volume of cells or particles
US7560269B2 (en) 2002-12-20 2009-07-14 Acea Biosciences, Inc. Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
US8263375B2 (en) 2002-12-20 2012-09-11 Acea Biosciences Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
US7470533B2 (en) 2002-12-20 2008-12-30 Acea Biosciences Impedance based devices and methods for use in assays
US8206903B2 (en) 2002-12-20 2012-06-26 Acea Biosciences Device and method for electroporation-based delivery of molecules into cells and dynamic monitoring of cell responses
US7732127B2 (en) * 2002-12-20 2010-06-08 Acea Biosciences, Inc. Dynamic monitoring of cell adhesion and spreading using the RT-CES system
ATE442587T1 (de) * 2002-07-20 2009-09-15 Acea Biosciences Inc Impedanz basierende vorrichtungen und verfahren zur analyse von zellen und partikeln
US7468255B2 (en) * 2002-12-20 2008-12-23 Acea Biosciences Method for assaying for natural killer, cytotoxic T-lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology
US7143785B2 (en) 2002-09-25 2006-12-05 California Institute Of Technology Microfluidic large scale integration
WO2004040001A2 (en) 2002-10-02 2004-05-13 California Institute Of Technology Microfluidic nucleic acid analysis
EP1556169A1 (en) * 2002-10-30 2005-07-27 The Procter & Gamble Company Dynamic electrostatic aerosol collection apparatus for collecting and sampling airborne particulate matter
US10215748B2 (en) 2002-12-20 2019-02-26 Acea Biosciences, Inc. Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways
US10551371B2 (en) 2003-11-10 2020-02-04 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function
US10539523B2 (en) 2002-12-20 2020-01-21 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology, and electrophysiological properties
US11346797B2 (en) 2002-12-20 2022-05-31 Agilent Technologies, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties
US9612234B2 (en) 2008-05-05 2017-04-04 Acea Biosciences, Inc. Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (RTCA) cardio instruments
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
US7476363B2 (en) 2003-04-03 2009-01-13 Fluidigm Corporation Microfluidic devices and methods of using same
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
US20050145496A1 (en) 2003-04-03 2005-07-07 Federico Goodsaid Thermal reaction device and method for using the same
US8828663B2 (en) 2005-03-18 2014-09-09 Fluidigm Corporation Thermal reaction device and method for using the same
US7413712B2 (en) 2003-08-11 2008-08-19 California Institute Of Technology Microfluidic rotary flow reactor matrix
CA2550274A1 (en) 2003-11-12 2005-05-26 Acea Biosciences, Inc. Real time electronic cell sensing systems and applications for cell-based assays
JP4911601B2 (ja) * 2004-02-10 2012-04-04 ベックマン コールター， インコーポレイテッド 有核赤血球細胞の計測方法
US7208319B2 (en) * 2004-02-10 2007-04-24 Beckman Coulter, Inc. Method of measurement of nucleated red blood cells
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7225682B2 (en) * 2004-06-22 2007-06-05 Concretec Ltd. Method, apparatus and system for monitoring hardening and forecasting strength of cementitious material
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
CA2855108A1 (en) * 2005-02-10 2006-08-17 Koninklijke Philips Electronics N.V. Dual sample cartridge and method for characterizing particles in liquid
JP5096170B2 (ja) 2005-02-10 2012-12-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ デュアルサンプルカートリッジ及び液体中の粒子を特徴付ける方法
US7531357B2 (en) * 2005-04-04 2009-05-12 Bio-Rad Laboratories, Inc. Preparation of platelet analogs
US7235404B2 (en) * 2005-05-04 2007-06-26 Beckman Coulter, Inc. Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement
US7417418B1 (en) 2005-06-14 2008-08-26 Ayliffe Harold E Thin film sensor
US7451646B2 (en) * 2005-07-28 2008-11-18 The Regents Of The University Of California Device and method for resonant high-speed microscopic impedance probe
US7482165B2 (en) * 2005-08-24 2009-01-27 Beckman Coulter, Inc. Method of preventing white blood cell interferences to red blood cell measurements of a blood sample
US7586589B2 (en) * 2005-09-24 2009-09-08 Beckman Coulter, Inc. Methods of determination of responsiveness to erythropoietin treatment
US7609369B2 (en) * 2005-09-24 2009-10-27 Beckman Coulter, Inc. Methods of detection of iron deficiency and hemochromatosis
CA2624229A1 (en) * 2005-09-30 2007-04-05 Pulse-Immunotech Corporation Method of assaying substance with affinity in sample containing blood-cell ingredient
US20090117667A1 (en) * 2005-09-30 2009-05-07 Pulse-Immunotech Corporation Methods for measuring affinity substances in samples comprising step of disrupting blood cell components
US7397232B2 (en) * 2005-10-21 2008-07-08 The University Of Akron Coulter counter having a plurality of channels
EP1984738A2 (en) 2006-01-11 2008-10-29 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
US7361512B2 (en) * 2006-01-20 2008-04-22 Beckman Coulter, Inc. Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency
US8616048B2 (en) * 2006-02-02 2013-12-31 E I Spectra, LLC Reusable thin film particle sensor
US7520164B1 (en) 2006-05-05 2009-04-21 E.I. Spectra, Llc Thin film particle sensor
US9293311B1 (en) 2006-02-02 2016-03-22 E. I. Spectra, Llc Microfluidic interrogation device
US9452429B2 (en) 2006-02-02 2016-09-27 E. I. Spectra, Llc Method for mutiplexed microfluidic bead-based immunoassay
US8171778B2 (en) * 2006-05-05 2012-05-08 E I Spectra, LLC Thin film particle sensor
US20110189714A1 (en) * 2010-02-03 2011-08-04 Ayliffe Harold E Microfluidic cell sorter and method
WO2009126257A1 (en) 2008-04-07 2009-10-15 E.I. Spectra, Llc Method for manufactiring a microfluidic sensor
WO2007119081A1 (en) * 2006-04-19 2007-10-25 Institut Rudjer Boskovic Amperometric method and apparatus for measurement of soft particles in liquids by analyzing the adhesion of these particeles to an electrode
EP2481815B1 (en) 2006-05-11 2016-01-27 Raindance Technologies, Inc. Microfluidic devices
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP3536396B1 (en) 2006-08-07 2022-03-30 The President and Fellows of Harvard College Fluorocarbon emulsion stabilizing surfactants
US7288219B1 (en) 2006-08-30 2007-10-30 Ermi Roos Method and apparatus for size measurement of particles of carbon black
US8041515B2 (en) * 2006-09-20 2011-10-18 Acea Biosciences, Inc. Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US8592221B2 (en) 2007-04-19 2013-11-26 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
JP5681965B2 (ja) * 2007-09-26 2015-03-11 瑞穂 森田 検出素子およびそれを用いた検出装置
EP2195114B1 (en) 2007-09-29 2017-03-22 El Spectra, LLC Instrumented pipette tip
EP2214833A4 (en) * 2007-11-27 2012-11-14 El Spectra Llc PIPETTE INSTRUMENT ON FLUORESCENCE BASIS
ITTO20080104A1 (it) * 2008-02-08 2009-08-09 Silicon Biosystems Spa Apparato e metodo per il conteggio e l'identificazione di particelle di interesse in un fluido
JP5693973B2 (ja) * 2008-03-03 2015-04-01 コーニンクレッカ フィリップス エヌ ヴェ 高分解能分類
WO2009137440A1 (en) 2008-05-05 2009-11-12 Acea Biosciences, Inc. Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution
US20100122907A1 (en) * 2008-05-06 2010-05-20 Government of the United States of America, Single molecule mass or size spectrometry in solution using a solitary nanopore
NZ590166A (en) * 2008-06-30 2013-09-27 Microbix Biosystems Inc Method and apparatus for sorting cells
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
EP4047367A1 (en) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Method for detecting target analytes with droplet libraries
WO2010037085A1 (en) 2008-09-29 2010-04-01 The Board Of Trustees Of The University Of Illinois Dna sequencing and amplification systems using nanoscale field effect sensor arrays
US8522604B2 (en) * 2008-10-31 2013-09-03 The University Of Akron Metal wear detection apparatus and method employing microfluidic electronic device
WO2010054180A1 (en) * 2008-11-07 2010-05-14 Beckman Coulter, Inc. High sensitivity parameters for the detection of vitamin b12 and/or folate deficiencies and methods of use
EP2356465B1 (en) 2008-11-13 2014-10-01 Beckman Coulter, Inc. Method of correction of particle interference to hemoglobin measurement
FR2939199B1 (fr) 2008-12-02 2011-02-11 C2 Diagnostics Procede et dispositif de cytometrie en flux sans fluide de gainage
DE102009007060B4 (de) 2009-02-02 2014-07-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Statistisches Verfahren zur resistiven Bestimmung der Partikeldichte und Partikelgröße in Flüssigkeiten und Vorrichtung zur Durchführung des Verfahrens
US8528589B2 (en) 2009-03-23 2013-09-10 Raindance Technologies, Inc. Manipulation of microfluidic droplets
US8395398B2 (en) * 2009-04-24 2013-03-12 Beckman Coulter, Inc. Method of characterizing particles
US8665439B2 (en) * 2009-06-30 2014-03-04 Microbix Biosystems, Inc. Method and apparatus for limiting effects of refraction in cytometry
US8621943B2 (en) 2009-09-30 2014-01-07 Weyerhaeuser Nr Company Method of singulating embryos
WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
WO2011079176A2 (en) 2009-12-23 2011-06-30 Raindance Technologies, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
US8906308B2 (en) 2010-01-15 2014-12-09 Abbott Laboratories Method for determining volume and hemoglobin content of individual red blood cells
GB2477287B (en) * 2010-01-27 2012-02-15 Izon Science Ltd Control of particle flow in an aperture
US20110192723A1 (en) * 2010-02-08 2011-08-11 Genia Technologies, Inc. Systems and methods for manipulating a molecule in a nanopore
US9605307B2 (en) * 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
WO2011100604A2 (en) 2010-02-12 2011-08-18 Raindance Technologies, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
WO2012045012A2 (en) 2010-09-30 2012-04-05 Raindance Technologies, Inc. Sandwich assays in droplets
US9999886B2 (en) * 2010-10-07 2018-06-19 The Regents Of The University Of California Methods and systems for on demand droplet generation and impedance based detection
JP5617532B2 (ja) 2010-10-29 2014-11-05 ソニー株式会社 誘電サイトメトリ装置及び誘電サイトメトリによる細胞分取方法
US9976973B2 (en) 2010-11-09 2018-05-22 The General Hospital Corporation Counting particles using an electrical differential counter
US8973531B2 (en) * 2010-12-09 2015-03-10 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Automated continuous zooplankton culture system
JP5410406B2 (ja) 2010-12-13 2014-02-05 日本光電工業株式会社 血液測定装置
GB2500360B (en) 2010-12-22 2019-10-23 Genia Tech Inc Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
US9581563B2 (en) 2011-01-24 2017-02-28 Genia Technologies, Inc. System for communicating information from an array of sensors
US9110478B2 (en) 2011-01-27 2015-08-18 Genia Technologies, Inc. Temperature regulation of measurement arrays
US8901914B2 (en) 2011-01-31 2014-12-02 The Regents Of The University Of California High throughput label free nanoparticle detection and size assay
WO2012109600A2 (en) 2011-02-11 2012-08-16 Raindance Technologies, Inc. Methods for forming mixed droplets
WO2012112641A1 (en) 2011-02-15 2012-08-23 Microbix Biosystems Inc. Methods, systems, and apparatus for performing flow cytometry
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
US9347929B2 (en) 2011-03-01 2016-05-24 The Regents Of The University Of Michigan Controlling translocation through nanopores with fluid wall
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
EP3709018A1 (en) 2011-06-02 2020-09-16 Bio-Rad Laboratories, Inc. Microfluidic apparatus for identifying components of a chemical reaction
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
US10175195B2 (en) 2011-07-27 2019-01-08 The Board Of Trustees Of The University Of Illinois Nanopore sensors for biomolecular characterization
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
WO2013136430A1 (ja) 2012-03-13 2013-09-19 株式会社 東芝 一粒子解析装置および解析方法
US8804105B2 (en) 2012-03-27 2014-08-12 E. I. Spectra, Llc Combined optical imaging and electrical detection to characterize particles carried in a fluid
WO2013177560A1 (en) 2012-05-25 2013-11-28 The Regents Of The University Of California Microfluidic systems for particle trapping and separation
US8735853B2 (en) 2012-06-09 2014-05-27 E.I. Spectra, Llc Fluorescence flow cytometry
CN104350162A (zh) 2012-06-15 2015-02-11 吉尼亚科技公司 芯片设置和高精确度核酸测序
US9605309B2 (en) 2012-11-09 2017-03-28 Genia Technologies, Inc. Nucleic acid sequencing using tags
US9423336B2 (en) 2013-01-24 2016-08-23 Beckman Coulter, Inc. Systems and methods for particle sensing and characterization
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
US9557292B2 (en) 2013-02-25 2017-01-31 The Regents Of The University Of Michigan Nanopore-based determination of protein charge, shape, volume, rotational diffusion coefficient, and dipole moment
WO2014144868A1 (en) 2013-03-15 2014-09-18 Beckman Coulter, Inc. Compound optical flow cells and method of manufacture and use
US9753009B2 (en) 2013-04-17 2017-09-05 Revalesio Corporation Methods and apparatus for trapping and size resolution of nanoparticles and nanobubbles
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
DK3058337T3 (en) 2013-10-15 2019-04-15 Ecole Polytechnique Fed Lausanne Epfl MEASUREMENT TIP WITH ELECTRIC IMPEDANCE SENSOR
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
EP3640349A3 (en) 2013-10-23 2020-07-29 Roche Sequencing Solutions, Inc. High speed molecular sensing with nanopores
US9322062B2 (en) 2013-10-23 2016-04-26 Genia Technologies, Inc. Process for biosensor well formation
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
EP3090063B1 (en) 2013-12-31 2019-11-06 Bio-Rad Laboratories, Inc. Method for detection of latent retrovirus
WO2016166729A1 (en) 2015-04-15 2016-10-20 Ecole Polytechnique Federale De Lausanne (Epfl) Devices, systems and methods for dispensing and analysing particles
WO2016180918A1 (en) 2015-05-12 2016-11-17 Platod Combination of pharmacological and microfluidic features for improved platelets production
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
US9862941B2 (en) 2015-10-14 2018-01-09 Pioneer Hi-Bred International, Inc. Single cell microfluidic device
US12066428B2 (en) 2015-11-20 2024-08-20 Agilent Technologies, Inc. Cell-substrate impedance monitoring of cancer cells
WO2018027107A1 (en) 2016-08-05 2018-02-08 Trustees Of Boston University Method and device for antibiotic susceptibility testing based on fluctuations of electrical resistance in a microchannel
EP3525933B1 (en) 2016-10-11 2024-07-03 The Regents of the University of California Systems and methods to encapsulate and preserve organic matter for analysis
EP3349005A1 (en) 2017-01-16 2018-07-18 Fundació Institut Català de Nanociència i Nanotecnologia Sensors for translocating analytes comprising nanometer or sub-nanometer thick heterostructured functional layers and a method for sensing translocating analytes
US11746328B2 (en) 2017-03-03 2023-09-05 Agilent Technologies, Inc. Methods and systems for functional maturation of iPSC and ESC derived cardiomyocytes
EP3592695A1 (en) 2017-03-09 2020-01-15 Ecole Polytechnique Federale de Lausanne (EPFL) Microfluidic sensor and method for obtaining such a sensor
US11517901B2 (en) 2017-06-09 2022-12-06 The Regents Of The University Of California High-efficiency particle encapsulation in droplets with particle spacing and downstream droplet sorting
WO2018227210A1 (en) 2017-06-09 2018-12-13 The Regents Of The University Of California High-efficiency encapsulation in droplets based on hydrodynamic vortices control
WO2019075409A1 (en) 2017-10-12 2019-04-18 The Regents Of The University Of California ISOLATION AND IDENTIFICATION WITHOUT MICROFLUIDIC LABEL OF CELLS USING FLUORESCENCE LIFE IMAGING (FLIM)
WO2019079787A1 (en) 2017-10-20 2019-04-25 The Regents Of The University Of California MICROFLUIDIC SYSTEMS AND METHODS FOR CELL TRANSFECTION VIA LIPOFLEX
US11499127B2 (en) 2017-10-20 2022-11-15 The Regents Of The University Of California Multi-layered microfluidic systems for in vitro large-scale perfused capillary networks
EP3789751B1 (en) 2018-04-28 2024-06-26 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Method and system for determining platelet concentration
CN108680461B (zh) * 2018-05-18 2024-06-14 招远市大明仪表有限公司 一种全量程溶液浓度检测变送器及检测方法
EP3803399A4 (en) 2018-06-05 2022-03-09 Chronus Health, Inc. DEVICES, CARTRIDGES AND SENSORS FOR CONTROL OF FLUID MOVEMENT AND ANALYSIS OF BIOLOGICAL SAMPLES
US11440007B2 (en) 2018-10-02 2022-09-13 Lawrence Livermore National Security, Llc Electrical sensing, tracking, and actuation of droplets
EP3647405A1 (en) 2018-11-02 2020-05-06 Microfluidx Cell culture device and method of using the same
CN109765253B (zh) * 2019-01-04 2022-05-10 潍坊华鼎电子技术有限公司 一种增强器输出屏用荧光粉浆料的检测方法
AU2020215595B2 (en) 2019-02-01 2023-05-11 Labcyte Inc. Acoustic concentration, transfer and analysis of samples containing particles
CN113508285A (zh) * 2019-03-12 2021-10-15 国立大学法人东北大学 内毒素检测装置、及内毒素的检测方法
CN109959585B (zh) * 2019-04-08 2024-01-19 生态环境部南京环境科学研究所 一种入河口悬浮物分级计量装置
US11161109B2 (en) 2019-09-19 2021-11-02 Invidx Corp. Point-of-care testing cartridge with sliding cap
US11327084B2 (en) 2019-09-19 2022-05-10 Invidx Corp. Joint hematology and biochemistry point-of-care testing system
CN111999490B (zh) 2019-12-19 2021-07-30 瑞芯智造(深圳)科技有限公司 一种检测样品体系中微量蛋白的方法
USD941488S1 (en) 2020-02-07 2022-01-18 Agilent Technologies, Inc. Instrument for analyzing biological cells
US20210301245A1 (en) 2020-03-29 2021-09-30 Agilent Technologies, Inc. Systems and methods for electronically and optically monitoring biological samples
EP3985379A1 (de) 2020-10-13 2022-04-20 Charité - Universitätsmedizin Berlin Vorrichtung und verfahren zur messung einer in situ simulierten virusausbreitung in aerosolen
US12011715B2 (en) 2020-11-11 2024-06-18 International Business Machines Corporation Tailorable electrode capping for microfluidic devices
WO2023186905A1 (en) 2022-03-29 2023-10-05 LAVA Therapeutics N.V. A method of treating a hematological cancer following screening for cd1d positive tumor cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1070556A (en) * 1913-01-03 1913-08-19 William Walker Strong Device for detecting suspended matter in gases.
US1168227A (en) * 1913-01-30 1916-01-11 Int Precipitation Co Method and means for indicating suspended matter in gases.
US1995492A (en) * 1928-06-11 1935-03-26 Smith Corp A O Device for determining the composition of fluid bodies in motion and for selectively distributing the flow of portions of said bodies to predetermined locations
DE542197C (de) * 1930-01-29 1932-01-21 I G Farbenindustrie Akt Ges Verfahren und Vorrichtung zur Messung der Konzentration von stroemenden Elektrolyten
US2122363A (en) * 1935-07-02 1938-06-28 Soren L Christie Concentration testing apparatus and method
US2262370A (en) * 1939-08-18 1941-11-11 Westinghouse Electric & Mfg Co Smoke meter
US2349992A (en) * 1939-10-23 1944-05-30 Schrader Walter Device for indicating contaminations in oil circulation systems
US2492768A (en) * 1947-09-18 1949-12-27 Gen Electric Cloud moisture meter
FR984042A (fr) * 1949-02-05 1951-07-02 Déceleur de liquides secondaires contenus dans un liquide primaire

Also Published As

Publication number Publication date
GB722418A (xx) 1955-01-26
US2656508A (en) 1953-10-20
FR1080716A (fr) 1954-12-13
DE964810C (de) 1957-05-29

Similar Documents

Publication Publication Date Title
AT166754B (xx)
AT193848B (xx)
NL74694C (xx)
BE488253A (xx)
BE486689A (xx)
BE155588A (xx)
BE437616A (xx)
BE449134A (xx)
BE488270A (xx)
BE457200A (xx)
NL94112C (xx)
BE476015A (xx)
BE488247A (xx)
BE476643A (xx)
BE476829A (xx)
BE479156A (xx)
BE480597A (xx)
BE480618A (xx)
BE482756A (xx)
BE483443A (xx)
BE483689A (xx)
BE485768A (xx)
BE485770A (xx)
BE486819A (xx)
BE487077A (xx)