NL8400910A - 17-esters van clobetasol en werkwijze voor het bereiden daarvan. - Google Patents

17-esters van clobetasol en werkwijze voor het bereiden daarvan. Download PDF

Info

Publication number
NL8400910A
NL8400910A NL8400910A NL8400910A NL8400910A NL 8400910 A NL8400910 A NL 8400910A NL 8400910 A NL8400910 A NL 8400910A NL 8400910 A NL8400910 A NL 8400910A NL 8400910 A NL8400910 A NL 8400910A
Authority
NL
Netherlands
Prior art keywords
epoxy
dione
diene
methylpregna
chloro
Prior art date
Application number
NL8400910A
Other languages
English (en)
Dutch (nl)
Original Assignee
Sicor Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicor Spa filed Critical Sicor Spa
Publication of NL8400910A publication Critical patent/NL8400910A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8400910A 1983-03-29 1984-03-22 17-esters van clobetasol en werkwijze voor het bereiden daarvan. NL8400910A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20334/83A IT1194178B (it) 1983-03-29 1983-03-29 Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti
IT2033483 1983-03-29

Publications (1)

Publication Number Publication Date
NL8400910A true NL8400910A (nl) 1984-10-16

Family

ID=11165811

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8400910A NL8400910A (nl) 1983-03-29 1984-03-22 17-esters van clobetasol en werkwijze voor het bereiden daarvan.

Country Status (10)

Country Link
JP (2) JPS59205399A (enExample)
CA (1) CA1220468A (enExample)
CH (1) CH661930A5 (enExample)
DK (1) DK42884A (enExample)
FI (1) FI840344L (enExample)
IT (1) IT1194178B (enExample)
NL (1) NL8400910A (enExample)
NO (1) NO840065L (enExample)
SE (1) SE8400145L (enExample)
YU (1) YU54684A (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108727458A (zh) * 2018-05-10 2018-11-02 浙江仙居仙乐药业有限公司 一种17-丙酸酯的合成方法
CN111944002A (zh) * 2020-07-29 2020-11-17 河南利华制药有限公司 一种倍氯米松二丙酸酯中间体及制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1253831A (en) * 1968-01-19 1971-11-17 Glaxo Lab Ltd 9alpha,21-DIHALOPREGNANE COMPOUNDS
JPS51125372A (en) * 1975-03-31 1976-11-01 Taisho Pharmaceut Co Ltd Aprocess for preparing pregnane steroid-17-ester-21-halides

Also Published As

Publication number Publication date
FI840344A7 (fi) 1984-09-30
SE8400145L (sv) 1984-09-30
JPS59205399A (ja) 1984-11-20
IT1194178B (it) 1988-09-14
JPS59205397A (ja) 1984-11-20
SE8400145D0 (sv) 1984-01-12
FI840344A0 (fi) 1984-01-27
JPS6228160B2 (enExample) 1987-06-18
NO840065L (no) 1984-10-01
DK42884D0 (da) 1984-01-31
IT8320334A0 (it) 1983-03-29
FI840344L (fi) 1984-09-30
YU54684A (en) 1986-10-31
CH661930A5 (en) 1987-08-31
DK42884A (da) 1984-09-30
CA1220468A (en) 1987-04-14

Similar Documents

Publication Publication Date Title
FI78111B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 3,20-dioxo-1,4-pregnadien-17 -ol 17-aromatisk- heterocykliska karboxylater.
EP0061416B1 (en) Process for the preparation of delta 9(11)- and delta 16-21-chloro-20-keto steroids of the pregnane and d-homopregnane series and their use as intermediates for the synthesis of highly effective corticoids
US4255331A (en) 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones
NL8400910A (nl) 17-esters van clobetasol en werkwijze voor het bereiden daarvan.
US7718793B2 (en) Method for the preparation of 6-α fluoro corticosteroids
CA2450661C (en) Preparation of flumethasone and its 17-carboxyl androsten analogue
KR20030081329A (ko) 트랜스케탈화 반응에 의한 16,17-[(시클로헥실메틸렌)비스(옥시)]-11,21-디히드록시-프레그나-1,4-디엔-3,20-디온또는 이의 21-이소부티라트의 제조방법
AU2002310616A1 (en) Preparation of flumethasone and its 17-carboxyl androsten analogue
JP2004534795A5 (enExample)
NO327138B1 (no) Fremgangsmate for fremstilling av flutikasonpropionat som krystallinsk polymorf form 1
KR880001238B1 (ko) 9α-플루오로-또는 클로로-코티코스테로이드 에스테르의 제조방법
EP0027192A1 (en) A process for the preparation of 4,6-dien-3-one steroids
US4207235A (en) Selective epoxidation of steroidal bromohydrins
US5670676A (en) Process for preparation of 9α -chloro-11β formyloxypregna-3.20-diones
WO2025132164A1 (en) Method for producing alclometasone dipropionate and intermediates thereof
US5602248A (en) Process for preparation of 9α-chloro-11β-formyloxypregna-3,20-diones
KR800000556B1 (ko) 17 α-에스테르-21 할로 프레그난류의 제법
CN119264206A (zh) 一种甾体环氧化物开环氟化的方法
WO2001055171A1 (en) Mometasone and its preparation
KR840000155B1 (ko) 6α, 9α-디플루오로-16-메틸-프레드니솔론 17, 21-디에스테르의 제조방법
EA000731B1 (ru) ПОЛУЧЕНИЕ (11β, 16β)-21-(3-КАРБОКСИ-3-ОКСОПРОПОКСИ)-11-ГИДРОКСИ-2'-МЕТИЛ-5'Н-ПРЕГНА-1,4-ДИЕНО[17,16-D]-ОКСАЗОЛ-3,20-ДИОНА
JPH0122280B2 (enExample)
HU200610B (en) New process for producing 21-halogen pregnane derivatives
JPS6363555B2 (enExample)

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
A85 Still pending on 85-01-01
BB A search report has been drawn up
BV The patent application has lapsed