NL8303657A - Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan. - Google Patents

Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan. Download PDF

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Publication number
NL8303657A
NL8303657A NL8303657A NL8303657A NL8303657A NL 8303657 A NL8303657 A NL 8303657A NL 8303657 A NL8303657 A NL 8303657A NL 8303657 A NL8303657 A NL 8303657A NL 8303657 A NL8303657 A NL 8303657A
Authority
NL
Netherlands
Prior art keywords
solution
cis
platinum
aqueous
stable
Prior art date
Application number
NL8303657A
Other languages
English (en)
Dutch (nl)
Original Assignee
Pharmachemie Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmachemie Bv filed Critical Pharmachemie Bv
Priority to NL8303657A priority Critical patent/NL8303657A/nl
Priority to FI843286A priority patent/FI78837C/fi
Priority to AU32269/84A priority patent/AU576204B2/en
Priority to IL72829A priority patent/IL72829A/xx
Priority to DE8484201425T priority patent/DE3464849D1/de
Priority to EP84201425A priority patent/EP0143478B1/de
Priority to AT84201425T priority patent/ATE28402T1/de
Priority to JP59222864A priority patent/JPS60172923A/ja
Priority to NO844225A priority patent/NO165277C/no
Priority to DK504384A priority patent/DK160806C/da
Priority to ES537033A priority patent/ES9300011A1/es
Publication of NL8303657A publication Critical patent/NL8303657A/nl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Escalators And Moving Walkways (AREA)
  • Hydraulic Clutches, Magnetic Clutches, Fluid Clutches, And Fluid Joints (AREA)
  • Excavating Of Shafts Or Tunnels (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
NL8303657A 1983-10-24 1983-10-24 Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan. NL8303657A (nl)

Priority Applications (11)

Application Number Priority Date Filing Date Title
NL8303657A NL8303657A (nl) 1983-10-24 1983-10-24 Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
FI843286A FI78837C (fi) 1983-10-24 1984-08-20 Foerfarande foer framstaellning av en foer injektionsadministration laemplig, stabil och saltsyrahaltig vattenloesning av cis-platina.
AU32269/84A AU576204B2 (en) 1983-10-24 1984-08-22 Aqueous, injectable solutions of cis-platimum
IL72829A IL72829A (en) 1983-10-24 1984-08-31 Stable,aqueous,acidic solution of cis-platinum,suitable for injection
DE8484201425T DE3464849D1 (en) 1983-10-24 1984-10-04 Stable, aqueous, acidic solution of cis-platinum, suitable for injection
EP84201425A EP0143478B1 (de) 1983-10-24 1984-10-04 Stabile, wässerige, saure, zur Einspritzung geeignete Lösung von Cis-Platinum
AT84201425T ATE28402T1 (de) 1983-10-24 1984-10-04 Stabile, waesserige, saure, zur einspritzung geeignete loesung von cis-platinum.
JP59222864A JPS60172923A (ja) 1983-10-24 1984-10-22 シスジクロロジアンミン白金を含有する安定な注射液に適した水溶液
NO844225A NO165277C (no) 1983-10-24 1984-10-23 Fremgangsmaate for fremstilling av en stabil, vandig, sur opploesning av cis-platina.
DK504384A DK160806C (da) 1983-10-24 1984-10-23 Stabil, vandig syreoploesning af cis-platin egnet til injektion og fremgangsmaade til fremstilling heraf
ES537033A ES9300011A1 (es) 1983-10-24 1984-10-24 Un procedimiento para preparar una solucion de cis-platino que contiene acido clarhidrico acuosa estable

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8303657A NL8303657A (nl) 1983-10-24 1983-10-24 Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
NL8303657 1983-10-24

Publications (1)

Publication Number Publication Date
NL8303657A true NL8303657A (nl) 1985-05-17

Family

ID=19842603

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8303657A NL8303657A (nl) 1983-10-24 1983-10-24 Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.

Country Status (11)

Country Link
EP (1) EP0143478B1 (de)
JP (1) JPS60172923A (de)
AT (1) ATE28402T1 (de)
AU (1) AU576204B2 (de)
DE (1) DE3464849D1 (de)
DK (1) DK160806C (de)
ES (1) ES9300011A1 (de)
FI (1) FI78837C (de)
IL (1) IL72829A (de)
NL (1) NL8303657A (de)
NO (1) NO165277C (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL83380A (en) * 1987-07-30 1991-04-15 Teva Pharma Stable aqueous cisplatin solutions
NL8901433A (nl) * 1989-06-06 1991-01-02 Pharmachemie Bv Carboplatinpreparaat.
US5466678A (en) * 1992-09-04 1995-11-14 Fuji Kagaku Kogyo Kabushiki Kaisha Co-administration of S-adenosyl-L-methionine to reduce the nephrotoxicity of cisplatin therapy
US6861422B2 (en) 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
DE102004029784A1 (de) 2004-06-21 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
DE102004033670A1 (de) 2004-07-09 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
US7728134B2 (en) 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US7759485B2 (en) 2004-08-14 2010-07-20 Boehringer Ingelheim International Gmbh Process for the manufacture of dihydropteridinones
US20060035903A1 (en) 2004-08-14 2006-02-16 Boehringer Ingelheim International Gmbh Storage stable perfusion solution for dihydropteridinones
US20060074088A1 (en) 2004-08-14 2006-04-06 Boehringer Ingelheim International Gmbh Dihydropteridinones for the treatment of cancer diseases
US20060058311A1 (en) 2004-08-14 2006-03-16 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation
EP1630163A1 (de) 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004058337A1 (de) 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
US7439358B2 (en) 2006-02-08 2008-10-21 Boehringer Ingelheim International Gmbh Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
EP2185559A1 (de) 2007-08-03 2010-05-19 Boehringer Ingelheim International GmbH Kristalline form eines dihydropteridionderivats
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
WO2015011236A1 (en) 2013-07-26 2015-01-29 Boehringer Ingelheim International Gmbh Treatment of myelodysplastic syndrome
US9867831B2 (en) 2014-10-01 2018-01-16 Boehringer Ingelheim International Gmbh Combination treatment of acute myeloid leukemia and myelodysplastic syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310515A (en) * 1978-05-30 1982-01-12 Bristol-Myers Company Pharmaceutical compositions of cisplatin
CA1119954A (en) * 1978-05-30 1982-03-16 Edmund S. Granatek Aqueous solution of cisplatin
US4302446A (en) * 1979-10-02 1981-11-24 Bristol-Myers Company Pharmaceutical compositions
AU541056B2 (en) * 1980-03-31 1984-12-13 Bristol-Myers Company Pharmaceuticals formulations
US4426372A (en) * 1980-08-08 1984-01-17 Regents Of The University Of Minnesota Inhibition of undesired effects of platinum(II) compounds
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento

Also Published As

Publication number Publication date
EP0143478A1 (de) 1985-06-05
FI843286A0 (fi) 1984-08-20
ATE28402T1 (de) 1987-08-15
DK504384D0 (da) 1984-10-23
DE3464849D1 (en) 1987-08-27
IL72829A (en) 1986-09-30
FI78837B (fi) 1989-06-30
ES9300011A1 (es) 1993-10-16
NO844225L (no) 1985-04-25
DK160806B (da) 1991-04-22
DK160806C (da) 1991-10-07
NO165277C (no) 1991-01-30
DK504384A (da) 1985-04-25
NO165277B (no) 1990-10-15
FI843286A (fi) 1985-04-25
FI78837C (fi) 1989-10-10
AU3226984A (en) 1985-06-13
EP0143478B1 (de) 1987-07-22
IL72829A0 (en) 1984-11-30
JPS60172923A (ja) 1985-09-06
AU576204B2 (en) 1988-08-18

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