NL8200746A - Verbinding met antitussive activiteit, werkwijze ter bereiding daarvan en toepassing. - Google Patents

Verbinding met antitussive activiteit, werkwijze ter bereiding daarvan en toepassing. Download PDF

Info

Publication number
NL8200746A
NL8200746A NL8200746A NL8200746A NL8200746A NL 8200746 A NL8200746 A NL 8200746A NL 8200746 A NL8200746 A NL 8200746A NL 8200746 A NL8200746 A NL 8200746A NL 8200746 A NL8200746 A NL 8200746A
Authority
NL
Netherlands
Prior art keywords
compound
preparing
propanediol
antitussive
antitussive activity
Prior art date
Application number
NL8200746A
Other languages
English (en)
Dutch (nl)
Original Assignee
Menarini Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Sas filed Critical Menarini Sas
Publication of NL8200746A publication Critical patent/NL8200746A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NL8200746A 1981-02-25 1982-02-24 Verbinding met antitussive activiteit, werkwijze ter bereiding daarvan en toepassing. NL8200746A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT934381 1981-02-25
IT8109343A IT1210639B (it) 1981-02-25 1981-02-25 Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione

Publications (1)

Publication Number Publication Date
NL8200746A true NL8200746A (nl) 1982-09-16

Family

ID=11128724

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8200746A NL8200746A (nl) 1981-02-25 1982-02-24 Verbinding met antitussive activiteit, werkwijze ter bereiding daarvan en toepassing.

Country Status (18)

Country Link
US (1) US4372958A (xx)
JP (1) JPS57188589A (xx)
AT (1) AT380881B (xx)
BE (1) BE892271A (xx)
CA (1) CA1192549A (xx)
CH (1) CH651043A5 (xx)
DE (1) DE3205149A1 (xx)
DK (1) DK148687C (xx)
ES (1) ES8302680A1 (xx)
FR (1) FR2500455A1 (xx)
GB (1) GB2093445B (xx)
GR (1) GR76060B (xx)
IT (1) IT1210639B (xx)
LU (1) LU83962A1 (xx)
NL (1) NL8200746A (xx)
PT (1) PT74463B (xx)
SE (1) SE440503B (xx)
YU (1) YU44007B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
IT1217950B (it) * 1988-06-28 1990-03-30 Dott Formenti Ind Chimica E Fa Sali di (r,s) 3 (4 fenil 1 piperazinil) 1,2 propandtolo
IT1231158B (it) * 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.
DE3938123A1 (de) * 1989-11-16 1991-05-23 Diehl Gmbh & Co Treibladungsanzuender
IT1318651B1 (it) * 2000-07-28 2003-08-27 Dompe Spa Sintesi di (+-)1,3-diossolani e loro risoluzione ottica.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3163649A (en) * 1964-12-29 Substituteb phenyl-piperazine
GB938646A (en) * 1961-03-16 1963-10-02 Henri Morren New piperazine derivatives
FR1384693A (fr) * 1963-10-08 1965-01-08 Electrochimie Soc Procédé de préparation d'esters méthallyliques
FR1554628A (xx) * 1967-05-23 1969-01-24

Also Published As

Publication number Publication date
YU44007B (en) 1990-02-28
DK148687B (da) 1985-09-02
IT1210639B (it) 1989-09-14
YU41282A (en) 1987-10-31
GB2093445B (en) 1985-02-27
FR2500455A1 (fr) 1982-08-27
ES509850A0 (es) 1983-02-01
ATA59982A (de) 1985-12-15
JPS57188589A (en) 1982-11-19
DK79982A (da) 1982-08-26
DK148687C (da) 1986-04-28
ES8302680A1 (es) 1983-02-01
CH651043A5 (it) 1985-08-30
CA1192549A (en) 1985-08-27
BE892271A (fr) 1982-06-16
GB2093445A (en) 1982-09-02
AT380881B (de) 1986-07-25
LU83962A1 (fr) 1982-07-08
DE3205149A1 (de) 1982-11-11
PT74463B (en) 1983-08-24
JPH0333715B2 (xx) 1991-05-20
PT74463A (en) 1982-03-01
IT8109343A0 (it) 1981-02-25
SE8201184L (sv) 1982-08-26
GR76060B (xx) 1984-08-03
SE440503B (sv) 1985-08-05
FR2500455B1 (xx) 1984-04-27
US4372958A (en) 1983-02-08
DE3205149C2 (xx) 1991-04-18

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed