NL8000277A - Nieuwe nor-tropaanverbindingen alsmede werkwijze ter bereiding en therapeutische toepassing van deze verbindingen. - Google Patents
Nieuwe nor-tropaanverbindingen alsmede werkwijze ter bereiding en therapeutische toepassing van deze verbindingen. Download PDFInfo
- Publication number
- NL8000277A NL8000277A NL8000277A NL8000277A NL8000277A NL 8000277 A NL8000277 A NL 8000277A NL 8000277 A NL8000277 A NL 8000277A NL 8000277 A NL8000277 A NL 8000277A NL 8000277 A NL8000277 A NL 8000277A
- Authority
- NL
- Netherlands
- Prior art keywords
- formula
- group
- amino
- methoxy
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7900971 | 1979-01-16 | ||
FR7900971A FR2446823A1 (fr) | 1979-01-16 | 1979-01-16 | Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique |
FR7931656A FR2476088A2 (fr) | 1979-01-16 | 1979-12-26 | Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique |
FR7931656 | 1979-12-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
NL8000277A true NL8000277A (nl) | 1980-07-18 |
Family
ID=26220957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL8000277A NL8000277A (nl) | 1979-01-16 | 1980-01-16 | Nieuwe nor-tropaanverbindingen alsmede werkwijze ter bereiding en therapeutische toepassing van deze verbindingen. |
Country Status (14)
Country | Link |
---|---|
US (2) | US4471120A (sv) |
AU (1) | AU542537B2 (sv) |
BE (1) | BE881134A (sv) |
CA (1) | CA1130286A (sv) |
CH (2) | CH647520A5 (sv) |
DE (2) | DE3001328A1 (sv) |
ES (1) | ES487721A1 (sv) |
FR (1) | FR2476088A2 (sv) |
GB (1) | GB2042522B (sv) |
GR (1) | GR66499B (sv) |
IT (2) | IT1148801B (sv) |
LU (1) | LU82083A1 (sv) |
NL (1) | NL8000277A (sv) |
SE (2) | SE444941B (sv) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL61642A0 (en) * | 1979-12-20 | 1981-01-30 | Beecham Group Ltd | Aniline derivatives,their preparation and pharmalceutical compositions containing them |
FR2493848B2 (fr) * | 1980-11-07 | 1986-05-16 | Delalande Sa | Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique |
NZ199080A (en) * | 1980-12-12 | 1984-07-31 | Beecham Group Ltd | 2-alkoxy-4-amino-5-alkylsulphonyl-n-(3beta-(8-hydrocarbyl-8-azabicyclo (3,2,1)octyl))benzamides |
DE3268378D1 (en) * | 1981-06-17 | 1986-02-20 | Beecham Group Plc | Alkylthio derivatives of azabicyclobenzamides, their preparation and pharmaceutical compositions |
EP0069481A1 (en) * | 1981-06-17 | 1983-01-12 | Beecham Group Plc | Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them |
EP0069482A1 (en) * | 1981-06-29 | 1983-01-12 | Beecham Group Plc | Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them |
EP0068700A1 (en) * | 1981-06-29 | 1983-01-05 | Beecham Group Plc | Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them |
EP0076592B1 (en) * | 1981-10-01 | 1987-01-28 | Beecham Group Plc | Azabicyclo-(3,3,1)-nonylbenzamide derivatives, processes for their preparation, and pharmaceutical compositions containing them |
EP0083737A1 (en) * | 1981-12-15 | 1983-07-20 | Beecham Group Plc | N-azabicycloalkane benzamides, process for their preparation and pharmaceutical compositions containing them |
EP0095262B1 (en) * | 1982-05-11 | 1986-12-03 | Beecham Group Plc | Azabicycloalkane derivatives, their preparation and medicaments containing them |
FR2531083B1 (fr) * | 1982-06-29 | 1986-11-28 | Sandoz Sa | Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments |
EP0126087A1 (en) * | 1982-09-24 | 1984-11-28 | Beecham Group Plc | Amino-azabicycloalkyl derivatives as dopamine antagonists |
CA1244028A (en) * | 1983-04-14 | 1988-11-01 | Hans Maag | Pyrimidine derivatives |
FR2546169B1 (fr) * | 1983-05-20 | 1986-03-21 | Delalande Sa | N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique |
CH664567A5 (de) * | 1983-08-26 | 1988-03-15 | Sandoz Ag | Aromatische carbonsaeure- und sulfonsaeureester oder -amide. |
DE3445377A1 (de) * | 1983-12-23 | 1985-07-04 | Sandoz-Patent-GmbH, 7850 Lörrach | Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen |
US4997956A (en) * | 1989-06-14 | 1991-03-05 | Eli Lilly And Company | Certain 2,3-dihydro-2;2-dimethyl-benzothiophene carboxylic acids which are intermediates |
US5364863A (en) * | 1987-09-08 | 1994-11-15 | Eli Lilly And Company | Specific 5-HT3 antagonists |
US4921982A (en) * | 1988-07-21 | 1990-05-01 | Eli Lilly And Company | 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists |
US5070094A (en) * | 1989-09-05 | 1991-12-03 | G. D. Searle & Co. | N-benzyltropaneamides |
GB9027487D0 (en) * | 1990-12-19 | 1991-02-06 | Beecham Group Plc | Pharmaceuticals |
FR2831884B1 (fr) | 2001-11-02 | 2003-12-26 | Pf Medicament | Nouveaux derives amides heteroaromatiques de 3 beta-amino azabicyclooctane, leur procede de preparation et leurs applications en therapeutique |
JP2009513491A (ja) | 2003-06-24 | 2009-04-02 | ノイロサーチ アクティーゼルスカブ | 新規な8−アザ−ビシクロ[3.2.1]オクタン誘導体、及びモノアミン神経伝達物質の再取り込み阻害剤としてのその使用 |
NZ599853A (en) * | 2008-04-11 | 2012-08-31 | Janssen Pharmaceutica Nv | Process for the preparation of meso-N-[(3-endo)-8-benzyl-8-azabicyclo[3.2.1]oct-3-yl]acetamide and its derivatives |
CA2761881C (en) * | 2009-05-14 | 2017-04-04 | Janssen Pharmaceutica Nv | Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3134782A (en) * | 1964-05-26 | Chjxch- | ||
FR1162129A (fr) * | 1954-10-20 | 1958-09-09 | Sandoz Ag | Dérivés amidés du tropane et leur préparation |
GB774858A (en) * | 1954-10-20 | 1957-05-15 | Sandoz Ltd | Tropane and -Î-tropane derivatives and process for preparation thereof |
CH374679A (de) * | 1958-11-26 | 1964-01-31 | Sandoz Ag | Verfahren zur Herstellung von neuen Tropan-Derivaten |
DE2513136C3 (de) * | 1974-03-21 | 1981-04-30 | Anphar S.A., Madrid | N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate |
GB1593146A (en) * | 1976-11-05 | 1981-07-15 | Beecham Group Ltd | Octahydro-quinolizinyl benzamide derivatives |
US4179567A (en) * | 1978-04-10 | 1979-12-18 | Sterling Drug Inc. | 2-Aryltropane compounds |
IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
US4321378A (en) * | 1979-01-16 | 1982-03-23 | Delalande S.A. | 8-(5-Pyrimidinecarboxamide)nor-tropane derivatives |
US4329466A (en) * | 1979-01-16 | 1982-05-11 | Delalande S.A. | Certain nor-tropan-8-amine-3-aryl or heteroaryl derivatives |
-
1979
- 1979-12-26 FR FR7931656A patent/FR2476088A2/fr active Granted
-
1980
- 1980-01-04 SE SE8000068A patent/SE444941B/sv not_active IP Right Cessation
- 1980-01-05 GR GR60908A patent/GR66499B/el unknown
- 1980-01-07 US US06/110,067 patent/US4471120A/en not_active Expired - Lifetime
- 1980-01-08 CA CA343,219A patent/CA1130286A/en not_active Expired
- 1980-01-08 IT IT19071/80A patent/IT1148801B/it active
- 1980-01-08 CH CH111/80A patent/CH647520A5/fr not_active IP Right Cessation
- 1980-01-11 GB GB8001037A patent/GB2042522B/en not_active Expired
- 1980-01-14 BE BE0/198955A patent/BE881134A/fr not_active IP Right Cessation
- 1980-01-14 LU LU82083A patent/LU82083A1/fr unknown
- 1980-01-15 AU AU54610/80A patent/AU542537B2/en not_active Ceased
- 1980-01-15 ES ES487721A patent/ES487721A1/es not_active Expired
- 1980-01-16 NL NL8000277A patent/NL8000277A/nl not_active Application Discontinuation
- 1980-01-16 DE DE19803001328 patent/DE3001328A1/de active Granted
- 1980-01-16 DE DE3049963A patent/DE3049963C2/de not_active Expired - Lifetime
- 1980-08-12 SE SE8005674A patent/SE431984B/sv not_active IP Right Cessation
- 1980-08-18 CH CH622080A patent/CH646969A5/fr not_active IP Right Cessation
- 1980-09-17 IT IT8024713A patent/IT1235424B/it active
-
1982
- 1982-07-19 US US06/399,392 patent/US4536580A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
SE444941B (sv) | 1986-05-20 |
DE3001328C2 (sv) | 1989-06-08 |
BE881134A (fr) | 1980-07-14 |
CH646969A5 (fr) | 1984-12-28 |
CH647520A5 (fr) | 1985-01-31 |
GR66499B (sv) | 1981-03-24 |
FR2476088B2 (sv) | 1983-11-04 |
ES487721A1 (es) | 1980-06-16 |
GB2042522B (en) | 1983-04-13 |
IT8024713A0 (it) | 1980-09-17 |
AU542537B2 (en) | 1985-02-28 |
SE431984B (sv) | 1984-03-12 |
LU82083A1 (fr) | 1981-09-10 |
IT1148801B (it) | 1986-12-03 |
US4471120A (en) | 1984-09-11 |
GB2042522A (en) | 1980-09-24 |
CA1130286A (en) | 1982-08-24 |
AU5461080A (en) | 1980-07-24 |
DE3049963C2 (de) | 1993-11-25 |
SE8000068L (sv) | 1980-07-17 |
US4536580A (en) | 1985-08-20 |
DE3001328A1 (de) | 1980-07-24 |
IT1235424B (it) | 1992-07-09 |
IT8019071A0 (it) | 1980-01-08 |
FR2476088A2 (fr) | 1981-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | A search report has been drawn up | ||
BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
A85 | Still pending on 85-01-01 | ||
BC | A request for examination has been filed | ||
BV | The patent application has lapsed | ||
BV | The patent application has lapsed |