IT1235424B - Derivati del beta-3-ammino-nortropano - Google Patents

Derivati del beta-3-ammino-nortropano

Info

Publication number
IT1235424B
IT1235424B IT8024713A IT2471380A IT1235424B IT 1235424 B IT1235424 B IT 1235424B IT 8024713 A IT8024713 A IT 8024713A IT 2471380 A IT2471380 A IT 2471380A IT 1235424 B IT1235424 B IT 1235424B
Authority
IT
Italy
Prior art keywords
beta
amino
nortropane
derivatives
nortropane derivatives
Prior art date
Application number
IT8024713A
Other languages
English (en)
Other versions
IT8024713A0 (it
Inventor
Dostert Philippe
Imbert Thierry
Bucher Bernard
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7900971A external-priority patent/FR2446823A1/fr
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of IT8024713A0 publication Critical patent/IT8024713A0/it
Application granted granted Critical
Publication of IT1235424B publication Critical patent/IT1235424B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT8024713A 1979-01-16 1980-09-17 Derivati del beta-3-ammino-nortropano IT1235424B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7900971A FR2446823A1 (fr) 1979-01-16 1979-01-16 Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
FR7931656A FR2476088A2 (fr) 1979-01-16 1979-12-26 Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
IT8024713A0 IT8024713A0 (it) 1980-09-17
IT1235424B true IT1235424B (it) 1992-07-09

Family

ID=26220957

Family Applications (2)

Application Number Title Priority Date Filing Date
IT19071/80A IT1148801B (it) 1979-01-16 1980-01-08 Derivati del nor-tropano, loro procedimento di preparazione e loro applicazione terapeutica
IT8024713A IT1235424B (it) 1979-01-16 1980-09-17 Derivati del beta-3-ammino-nortropano

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IT19071/80A IT1148801B (it) 1979-01-16 1980-01-08 Derivati del nor-tropano, loro procedimento di preparazione e loro applicazione terapeutica

Country Status (14)

Country Link
US (2) US4471120A (it)
AU (1) AU542537B2 (it)
BE (1) BE881134A (it)
CA (1) CA1130286A (it)
CH (2) CH647520A5 (it)
DE (2) DE3001328A1 (it)
ES (1) ES487721A1 (it)
FR (1) FR2476088A2 (it)
GB (1) GB2042522B (it)
GR (1) GR66499B (it)
IT (2) IT1148801B (it)
LU (1) LU82083A1 (it)
NL (1) NL8000277A (it)
SE (2) SE444941B (it)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61642A0 (en) * 1979-12-20 1981-01-30 Beecham Group Ltd Aniline derivatives,their preparation and pharmalceutical compositions containing them
FR2493848B2 (fr) * 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
ZA818221B (en) * 1980-12-12 1982-10-27 Beecham Group Plc Pharmaceutical compounds
EP0067615B1 (en) * 1981-06-17 1986-01-08 Beecham Group Plc Alkylthio derivatives of azabicyclobenzamides, their preparation and pharmaceutical compositions
EP0069481A1 (en) * 1981-06-17 1983-01-12 Beecham Group Plc Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them
EP0068700A1 (en) * 1981-06-29 1983-01-05 Beecham Group Plc Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them
EP0069482A1 (en) * 1981-06-29 1983-01-12 Beecham Group Plc Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them
DE3275296D1 (en) * 1981-10-01 1987-03-05 Beecham Group Plc Azabicyclo-(3,3,1)-nonylbenzamide derivatives, processes for their preparation, and pharmaceutical compositions containing them
EP0083737A1 (en) * 1981-12-15 1983-07-20 Beecham Group Plc N-azabicycloalkane benzamides, process for their preparation and pharmaceutical compositions containing them
DE3368061D1 (en) * 1982-05-11 1987-01-15 Beecham Group Plc Azabicycloalkane derivatives, their preparation and medicaments containing them
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
EP0126087A1 (en) * 1982-09-24 1984-11-28 Beecham Group Plc Amino-azabicycloalkyl derivatives as dopamine antagonists
CA1244028A (en) * 1983-04-14 1988-11-01 Hans Maag Pyrimidine derivatives
FR2546169B1 (fr) * 1983-05-20 1986-03-21 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
DE3429830A1 (de) * 1983-08-26 1985-03-07 Sandoz-Patent-GmbH, 7850 Lörrach Automatische carbonsaeure- und sulfonsaeureester oder -amide
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
US4997956A (en) * 1989-06-14 1991-03-05 Eli Lilly And Company Certain 2,3-dihydro-2;2-dimethyl-benzothiophene carboxylic acids which are intermediates
US5364863A (en) * 1987-09-08 1994-11-15 Eli Lilly And Company Specific 5-HT3 antagonists
US4921982A (en) * 1988-07-21 1990-05-01 Eli Lilly And Company 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists
US5070094A (en) * 1989-09-05 1991-12-03 G. D. Searle & Co. N-benzyltropaneamides
GB9027487D0 (en) * 1990-12-19 1991-02-06 Beecham Group Plc Pharmaceuticals
FR2831884B1 (fr) 2001-11-02 2003-12-26 Pf Medicament Nouveaux derives amides heteroaromatiques de 3 beta-amino azabicyclooctane, leur procede de preparation et leurs applications en therapeutique
CA2530023A1 (en) 2003-06-24 2004-12-29 Neurosearch A/S Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
ES2400875T3 (es) * 2008-04-11 2013-04-15 Janssen Pharmaceutica N.V. Tiazolopiridin-2-iloxi-fenil y tiazolopirazin-2-iloxi-fenil aminas como moduladores de la leucotrieno A4 hidrolasa
NZ596137A (en) 2009-05-14 2013-08-30 Janssen Pharmaceutica Nv Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3134782A (en) * 1964-05-26 Chjxch-
GB774858A (en) * 1954-10-20 1957-05-15 Sandoz Ltd Tropane and -Î-tropane derivatives and process for preparation thereof
FR1162129A (fr) * 1954-10-20 1958-09-09 Sandoz Ag Dérivés amidés du tropane et leur préparation
CH374679A (de) * 1958-11-26 1964-01-31 Sandoz Ag Verfahren zur Herstellung von neuen Tropan-Derivaten
DE2513136C3 (de) * 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
GB1593146A (en) * 1976-11-05 1981-07-15 Beecham Group Ltd Octahydro-quinolizinyl benzamide derivatives
US4179567A (en) * 1978-04-10 1979-12-18 Sterling Drug Inc. 2-Aryltropane compounds
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
US4321378A (en) * 1979-01-16 1982-03-23 Delalande S.A. 8-(5-Pyrimidinecarboxamide)nor-tropane derivatives
US4329466A (en) * 1979-01-16 1982-05-11 Delalande S.A. Certain nor-tropan-8-amine-3-aryl or heteroaryl derivatives

Also Published As

Publication number Publication date
IT1148801B (it) 1986-12-03
BE881134A (fr) 1980-07-14
LU82083A1 (fr) 1981-09-10
DE3001328A1 (de) 1980-07-24
SE8000068L (sv) 1980-07-17
CH647520A5 (fr) 1985-01-31
CA1130286A (en) 1982-08-24
CH646969A5 (fr) 1984-12-28
SE444941B (sv) 1986-05-20
IT8024713A0 (it) 1980-09-17
NL8000277A (nl) 1980-07-18
AU542537B2 (en) 1985-02-28
US4471120A (en) 1984-09-11
DE3001328C2 (it) 1989-06-08
GB2042522A (en) 1980-09-24
GB2042522B (en) 1983-04-13
AU5461080A (en) 1980-07-24
SE431984B (sv) 1984-03-12
FR2476088B2 (it) 1983-11-04
US4536580A (en) 1985-08-20
FR2476088A2 (fr) 1981-08-21
IT8019071A0 (it) 1980-01-08
ES487721A1 (es) 1980-06-16
DE3049963C2 (de) 1993-11-25
GR66499B (it) 1981-03-24

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960130