NL7111808A - - Google Patents
Info
- Publication number
- NL7111808A NL7111808A NL7111808A NL7111808A NL7111808A NL 7111808 A NL7111808 A NL 7111808A NL 7111808 A NL7111808 A NL 7111808A NL 7111808 A NL7111808 A NL 7111808A NL 7111808 A NL7111808 A NL 7111808A
- Authority
- NL
- Netherlands
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C07D333/80—Seven-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH359870A CH533639A (de) | 1970-03-11 | 1970-03-11 | Verfahren zur Herstellung neuer Benzo(4,5)cyclohepta(1,2-b)-thiophen-Derivate |
CH1159370A CH531000A (de) | 1970-03-11 | 1970-07-31 | Verfahren zur Herstellung neuer Benzocycloheptathiophene |
CH1412070A CH537404A (de) | 1970-09-24 | 1970-09-24 | Verfahren zur Herstellung neuer Thiophenderivate |
CH163271 | 1971-02-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
NL7111808A true NL7111808A (fr) | 1972-03-28 |
NL171449C NL171449C (nl) | 1983-04-05 |
Family
ID=27428249
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7103174.A NL167431C (nl) | 1970-03-11 | 1971-03-10 | Werkwijze voor de bereiding van een histaminolytisch werkend preparaat en werkwijze voor de bereiding van een histaminolytisch werkend 4-(1-alkyl-4-piperidyli- deen)benzo4,5cyclohepta1,2-bthiofeen |
NLAANVRAGE7111808,A NL171449C (nl) | 1970-03-11 | 1971-08-27 | Werkwijze ter bereiding van een met een aminoalkylideengroep gesubstitueerd tricyclisch keton. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7103174.A NL167431C (nl) | 1970-03-11 | 1971-03-10 | Werkwijze voor de bereiding van een histaminolytisch werkend preparaat en werkwijze voor de bereiding van een histaminolytisch werkend 4-(1-alkyl-4-piperidyli- deen)benzo4,5cyclohepta1,2-bthiofeen |
Country Status (12)
Country | Link |
---|---|
US (4) | US3682930A (fr) |
AT (2) | AT319238B (fr) |
BE (2) | BE764019A (fr) |
CA (2) | CA960673A (fr) |
CH (1) | CH531000A (fr) |
DE (2) | DE2111071C3 (fr) |
FR (2) | FR2085695B1 (fr) |
GB (4) | GB1355539A (fr) |
LU (2) | LU62757A1 (fr) |
NL (2) | NL167431C (fr) |
OA (2) | OA03692A (fr) |
SE (2) | SE368954B (fr) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH531000A (de) * | 1970-03-11 | 1972-11-30 | Sandoz Ag | Verfahren zur Herstellung neuer Benzocycloheptathiophene |
US3960894A (en) * | 1972-01-24 | 1976-06-01 | Sandoz Ltd. | 9-Bromo-or chloro-9,10-dihydro-10-dihydro-10-alkoxy-4H-benzo[4,5]cyclo-hepta[1,2-b]thiophen-4-ones |
BE794377A (fr) * | 1972-01-24 | 1973-07-23 | Sandoz Sa | Nouveaux derives du benzo-cyclohepta-thiophene |
US4072756A (en) * | 1973-05-17 | 1978-02-07 | Sandoz Ltd. | Tricyclo piperidino ketones and soporific compositions thereof |
CA1041100A (fr) * | 1973-10-04 | 1978-10-24 | Herbert G. Johnson | Acide pyridine-diyldioxamique |
CH580621A5 (fr) * | 1973-10-08 | 1976-10-15 | Sandoz Ag | |
US4073915A (en) * | 1975-05-20 | 1978-02-14 | Sandoz Ltd. | Treating asthma |
FI761607A (fr) * | 1975-06-16 | 1976-12-17 | Sandoz Ag | |
US4128549A (en) * | 1976-02-27 | 1978-12-05 | Sandoz Ltd. | Precursors of 4-(1-alkyl-4-piperidylidene-4H-benzo[4,5]cyclohepta-[1,2-b]thiophen-10(9H)-ones |
US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
DE3045135A1 (de) * | 1980-11-29 | 1982-06-09 | Sandoz-Patent-GmbH, 7850 Lörrach | Pharmazeutische kompositionen enthaltende bioabbaubare polymere |
HU202753B (en) * | 1986-06-21 | 1991-04-29 | Sandoz Ag | Process for producing retard pharmaceutical compositions containing cetotiphene |
US5438062A (en) * | 1986-10-31 | 1995-08-01 | Schering Corporation | Benzo(5,6)cycloheptapyridines, compositions and methods of use |
US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
DZ1460A1 (fr) * | 1989-11-22 | 2004-09-13 | Sod Conseils Rech Applic | Nouveaux dérivés du sélénophèn ainsi que leur procédé de préparation. |
CA2038417A1 (fr) * | 1990-04-11 | 1991-10-12 | Yasuo Ito | Composes de piperidine, methode de preparation de ces composes, et une composition pharmaceutique qui en contient. |
JPH089616B2 (ja) * | 1990-10-10 | 1996-01-31 | シェリング・コーポレーション | 置換されたイミダゾベンズアゼピン類およびイミダゾピリドアゼピン類 |
US5891460A (en) * | 1995-06-07 | 1999-04-06 | University Of Southern California University Park Campus | Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof |
EP1014979A4 (fr) | 1997-06-09 | 2003-08-20 | Bridge Pharma Inc | Composes a combinaison d'activites antihistaminique et stabilisatrice des membranes cellulaires de mastocytes, utilises a des fins ophtalmiques |
US6221897B1 (en) * | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
PL353586A1 (en) * | 1999-09-13 | 2003-12-01 | Bridge Pharma, Inc.Bridge Pharma, Inc. | Optically active isomers of ketotifen and therapeutically active metabolites thereof |
WO2001039774A1 (fr) * | 1999-12-01 | 2001-06-07 | Klein Pharmaceuticals | Administration topique de ketotifene |
US20030212078A1 (en) * | 2001-05-17 | 2003-11-13 | Klein Gerald L. | Topical administration of pharmacological compositions for non-systemic treatment of pruritus |
AU2004206827A1 (en) * | 2003-01-14 | 2004-08-05 | Gilead Sciences, Inc. | Compositions and methods for combination antiviral therapy |
CN100381439C (zh) * | 2005-04-05 | 2008-04-16 | 浙江华海药业股份有限公司 | 9,10-二溴-9,10-二氢-4-H苯并[4,5]环庚烯并[1,2-b]噻吩-4-酮的制备方法 |
TWI375560B (en) | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
WO2008153761A1 (fr) * | 2007-05-23 | 2008-12-18 | Mastcell Pharmaceuticals, Inc. | Méthodes |
TWI429641B (zh) | 2008-01-30 | 2014-03-11 | Nippon Zoki Pharmaceutical Co | 哌啶衍生物 |
WO2009142772A2 (fr) | 2008-05-23 | 2009-11-26 | Mastcell Pharmaceuticals, Inc. | Méthodes et traitement d’allergies et inflammations associées à des pathologies gastro-intestinales |
EP2319840B1 (fr) * | 2008-08-01 | 2015-12-16 | Nippon Zoki Pharmaceutical Co., Ltd. | Dérivé d'aminopropylidène |
AU2010279164A1 (en) * | 2009-07-28 | 2012-02-02 | Nippon Zoki Pharmaceutical Co., Ltd. | Method for producing thiabenzoazulene propionic acid derivative |
EA201891154A1 (ru) | 2011-10-28 | 2019-02-28 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Ингибиторы рециклинга желчных кислот при лечении холестатических заболеваний печени у детей |
US8557846B1 (en) | 2012-10-23 | 2013-10-15 | Bridge Pharma, Inc. | Medicinal treatment of dermal diseases in dogs |
US8778971B2 (en) | 2012-10-23 | 2014-07-15 | Bridge Pharma, Inc. | Medicinal treatment of dermal diseases in companion animals |
US20150272941A1 (en) | 2012-10-30 | 2015-10-01 | Bridge Pharma, Inc. | Medicinal treatment of chronic pulmonary inflammatory diseases with norketotifen |
US20140120121A1 (en) | 2012-10-30 | 2014-05-01 | Bridge Pharma, Inc. | Medicinal treatment of atopic inflammatory diseases |
US9345697B2 (en) | 2013-08-06 | 2016-05-24 | Bridge Pharma, Inc. | Methods of treatment of non-histaminic pruritus |
US9439895B2 (en) | 2013-08-06 | 2016-09-13 | Bridge Pharma, Inc. | Methods of treating pruritic conditions mediated through non-histaminergic mechanisms in diabetic patients |
US9138431B2 (en) | 2013-08-06 | 2015-09-22 | Bridge Pharma, Inc. | Methods of treatment of histamine H-4 receptor-related pruritus |
AU2016276022C1 (en) | 2015-06-11 | 2021-04-22 | Bridge Pharma, Inc. | Methods of treatment of non-histaminic pruritus in mammals |
MX2018011699A (es) | 2018-09-26 | 2019-07-24 | Federico Amezcua Amezcua | Composicion farmaceutica sinergica de un antagonista de los receptores de leucotrienos y un agonista inverso de la histamina h1. |
US10959992B2 (en) | 2019-02-22 | 2021-03-30 | Bridge Pharma Inc. | Methods of treatment of asthma and COPD |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL130095C (fr) * | 1962-08-31 | |||
US3491103A (en) * | 1963-12-19 | 1970-01-20 | Sandoz Ag | Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes |
FR1437412A (fr) * | 1963-12-19 | 1966-05-06 | Sandoz Sa | Nouveaux benzo-cyclohepta-thiophènes et leur préparation |
GB1084450A (en) * | 1963-12-20 | 1967-09-20 | Sandoz Ltd | Improvements in or relating to 4h-benzo[4,5]cyclohepta-[1,2-b] thiophene derivatives |
CH537897A (de) * | 1968-03-20 | 1973-06-15 | Hoffmann La Roche | Verfahren zur Herstellung von tricyclischen Verbindungen |
US3574199A (en) * | 1968-06-28 | 1971-04-06 | Searle & Co | 6-(aminoalkyl- and aminoalkylidene)-1,1a,6,10b -tetrahydro-dibenzo(a,e)cyclopropa(c)cycloheptenes |
CH531000A (de) * | 1970-03-11 | 1972-11-30 | Sandoz Ag | Verfahren zur Herstellung neuer Benzocycloheptathiophene |
US3709947A (en) * | 1971-07-26 | 1973-01-09 | Searle & Co | 6-chloropropylidene-1,1a,6,10b-tetrahydrobenzo(a,e)cyclopropa(c)cycloheptenes |
-
1970
- 1970-07-31 CH CH1159370A patent/CH531000A/de not_active IP Right Cessation
-
1971
- 1971-03-03 US US120738A patent/US3682930A/en not_active Expired - Lifetime
- 1971-03-08 FR FR7107901A patent/FR2085695B1/fr not_active Expired
- 1971-03-09 BE BE764019A patent/BE764019A/fr not_active IP Right Cessation
- 1971-03-09 OA OA54190A patent/OA03692A/fr unknown
- 1971-03-09 DE DE2111071A patent/DE2111071C3/de not_active Expired
- 1971-03-09 LU LU62757D patent/LU62757A1/xx unknown
- 1971-03-10 SE SE03074/71A patent/SE368954B/xx unknown
- 1971-03-10 AT AT206471A patent/AT319238B/de not_active IP Right Cessation
- 1971-03-10 CA CA107,340A patent/CA960673A/en not_active Expired
- 1971-03-10 NL NL7103174.A patent/NL167431C/xx not_active IP Right Cessation
- 1971-04-19 GB GB2882373A patent/GB1355539A/en not_active Expired
- 1971-04-19 GB GB2348271*A patent/GB1355537A/en not_active Expired
- 1971-06-04 GB GB1894073A patent/GB1355538A/en not_active Expired
- 1971-08-27 NL NLAANVRAGE7111808,A patent/NL171449C/xx not_active IP Right Cessation
- 1971-08-30 BE BE771964A patent/BE771964A/fr unknown
- 1971-08-31 CA CA121,762A patent/CA947767A/en not_active Expired
- 1971-09-02 LU LU63829D patent/LU63829A1/xx unknown
- 1971-09-02 AT AT766471A patent/AT321905B/de not_active IP Right Cessation
- 1971-09-03 SE SE7111154A patent/SE378820B/xx unknown
- 1971-09-03 FR FR7131866A patent/FR2107917B1/fr not_active Expired
- 1971-09-03 OA OA54351A patent/OA03786A/fr unknown
- 1971-09-06 DE DE19712144490 patent/DE2144490A1/de active Pending
- 1971-09-07 US US00178449A patent/US3770728A/en not_active Expired - Lifetime
- 1971-09-21 GB GB4392471A patent/GB1360219A/en not_active Expired
-
1972
- 1972-08-07 US US00278244A patent/US3749786A/en not_active Expired - Lifetime
- 1972-08-08 US US00278738A patent/US3853915A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US3749786A (en) | 1973-07-31 |
OA03692A (fr) | 1971-12-24 |
FR2085695A1 (fr) | 1971-12-31 |
US3853915A (en) | 1974-12-10 |
US3770728A (en) | 1973-11-06 |
BE771964A (fr) | 1972-02-29 |
FR2107917B1 (fr) | 1975-04-18 |
GB1355537A (en) | 1974-06-05 |
SE368954B (fr) | 1974-07-29 |
AT319238B (de) | 1974-12-10 |
LU63829A1 (fr) | 1972-06-27 |
CA947767A (en) | 1974-05-21 |
AT321905B (de) | 1975-04-25 |
FR2085695B1 (fr) | 1974-11-15 |
LU62757A1 (fr) | 1971-10-13 |
DE2144490A1 (de) | 1972-03-30 |
BE764019A (fr) | 1971-09-09 |
CA960673A (en) | 1975-01-07 |
GB1360219A (en) | 1974-07-17 |
FR2107917A1 (fr) | 1972-05-12 |
DE2111071B2 (de) | 1978-11-09 |
DE2111071A1 (de) | 1971-09-23 |
NL167431C (nl) | 1981-12-16 |
DE2111071C3 (de) | 1979-07-12 |
GB1355538A (en) | 1974-06-05 |
NL7103174A (fr) | 1971-09-14 |
US3682930A (en) | 1972-08-08 |
GB1355539A (en) | 1974-06-05 |
NL171449C (nl) | 1983-04-05 |
SE378820B (fr) | 1975-09-15 |
CH531000A (de) | 1972-11-30 |
OA03786A (fr) | 1971-12-24 |
Similar Documents
Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
V4 | Discontinued because of reaching the maximum lifetime of a patent |