NL6412251A - - Google Patents

Info

Publication number
NL6412251A
NL6412251A NL6412251A NL6412251A NL6412251A NL 6412251 A NL6412251 A NL 6412251A NL 6412251 A NL6412251 A NL 6412251A NL 6412251 A NL6412251 A NL 6412251A NL 6412251 A NL6412251 A NL 6412251A
Authority
NL
Netherlands
Application number
NL6412251A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL6412251A publication Critical patent/NL6412251A/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/74Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NL6412251A 1959-12-10 1964-10-21 NL6412251A (US20100012521A1-20100121-C00001.png)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85856459A 1959-12-10 1959-12-10
US260560A 1960-01-15 1960-01-15
US2468660A 1960-04-26 1960-04-26
US3873260A 1960-06-27 1960-06-27

Publications (1)

Publication Number Publication Date
NL6412251A true NL6412251A (US20100012521A1-20100121-C00001.png) 1966-01-25

Family

ID=27485190

Family Applications (2)

Application Number Title Priority Date Filing Date
NL6412250A NL6412250A (US20100012521A1-20100121-C00001.png) 1959-12-10 1964-10-21
NL6412251A NL6412251A (US20100012521A1-20100121-C00001.png) 1959-12-10 1964-10-21

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL6412250A NL6412250A (US20100012521A1-20100121-C00001.png) 1959-12-10 1964-10-21

Country Status (11)

Country Link
BE (4) BE598012A (US20100012521A1-20100121-C00001.png)
BR (1) BR6024755D0 (US20100012521A1-20100121-C00001.png)
CH (9) CH408045A (US20100012521A1-20100121-C00001.png)
CY (1) CY324A (US20100012521A1-20100121-C00001.png)
DE (5) DE1288610B (US20100012521A1-20100121-C00001.png)
ES (2) ES263123A1 (US20100012521A1-20100121-C00001.png)
GB (13) GB972963A (US20100012521A1-20100121-C00001.png)
MY (1) MY6500178A (US20100012521A1-20100121-C00001.png)
NL (2) NL6412250A (US20100012521A1-20100121-C00001.png)
OA (7) OA00816A (US20100012521A1-20100121-C00001.png)
SE (2) SE310887B (US20100012521A1-20100121-C00001.png)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1295563B (de) * 1963-05-29 1969-05-22 American Home Prod Verfahren zur Herstellung von 5-Phenyl-7-chlor-1, 2-dihydro-3H-1, 4-benzodiazepinon-(2)-4-oxyd
GB1333501A (en) * 1971-03-05 1973-10-10 Ravizza Spa Process for the preparation of 7-chlorobenzodiazepine de rivatives
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
NZ529582A (en) * 2001-06-07 2006-10-27 Neuro3D Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof
WO2003099773A1 (en) * 2002-05-24 2003-12-04 Millennium Pharmaceuticals, Inc. Ccr9 inhibitors and methods of use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2893992A (en) * 1959-07-07 I ii i i

Also Published As

Publication number Publication date
GB972964A (en) 1964-10-21
DE1445073A1 (de) 1968-10-31
GB972963A (en) 1964-10-21
CH418342A (de) 1966-08-15
GB972968A (en) 1964-10-21
SE310887B (US20100012521A1-20100121-C00001.png) 1969-05-19
DE1288610B (de) 1969-02-06
OA00816A (fr) 1967-11-15
NL6412250A (US20100012521A1-20100121-C00001.png) 1966-01-25
MY6500178A (en) 1965-12-31
OA00958A (fr) 1968-03-22
BE598008A (fr) 1961-06-09
OA00817A (fr) 1967-11-15
GB972970A (en) 1964-10-21
ES263123A1 (es) 1961-06-01
GB972976A (en) 1964-10-21
CH411910A (de) 1966-04-30
GB972969A (en) 1964-10-21
GB972962A (en) 1964-10-21
GB972966A (en) 1964-10-21
DE1290143B (de) 1969-03-06
GB972973A (en) 1964-10-21
BE598013A (fr) 1961-06-09
CH408940A (de) 1966-03-15
CH408045A (de) 1966-02-28
CY324A (en) 1965-11-03
GB972967A (en) 1964-10-21
DE1288609B (de) 1969-02-06
CH418341A (de) 1966-08-15
GB972965A (en) 1964-10-21
GB972972A (en) 1964-10-21
GB972961A (en) 1964-10-21
CH414652A (de) 1966-06-15
OA02384A (fr) 1970-05-05
ES263124A1 (es) 1961-06-01
BE598012A (fr) 1961-06-09
OA00953A (fr) 1968-03-22
CH414653A (de) 1966-06-15
OA02385A (fr) 1970-05-05
CH408029A (de) 1966-02-28
OA00959A (fr) 1968-03-22
CH396016A (de) 1965-07-31
BR6024755D0 (pt) 1973-05-24
DE1445908A1 (de) 1969-04-17
BE598015A (fr) 1961-06-09
SE318283B (US20100012521A1-20100121-C00001.png) 1969-12-08

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