NL300205I2 - N-enentiomeer van N-propargyl-1-aminoindaan voor de behandeling van - Google Patents
N-enentiomeer van N-propargyl-1-aminoindaan voor de behandeling vanInfo
- Publication number
- NL300205I2 NL300205I2 NL300205C NL300205C NL300205I2 NL 300205 I2 NL300205 I2 NL 300205I2 NL 300205 C NL300205 C NL 300205C NL 300205 C NL300205 C NL 300205C NL 300205 I2 NL300205 I2 NL 300205I2
- Authority
- NL
- Netherlands
- Prior art keywords
- propargyl
- subject invention
- aminoindan
- subject
- pharmaceutically acceptable
- Prior art date
Links
- RUOKEQAAGRXIBM-UHFFFAOYSA-N n-prop-2-ynyl-2,3-dihydro-1h-inden-1-amine Chemical compound C1=CC=C2C(NCC#C)CCC2=C1 RUOKEQAAGRXIBM-UHFFFAOYSA-N 0.000 title abstract 2
- 208000014674 injury Diseases 0.000 abstract 4
- 208000027418 Wounds and injury Diseases 0.000 abstract 3
- 230000006378 damage Effects 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 abstract 1
- 201000006474 Brain Ischemia Diseases 0.000 abstract 1
- 206010012289 Dementia Diseases 0.000 abstract 1
- 206010019196 Head injury Diseases 0.000 abstract 1
- 208000026139 Memory disease Diseases 0.000 abstract 1
- 208000028389 Nerve injury Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 abstract 1
- 208000035231 inattentive type attention deficit hyperactivity disease Diseases 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 230000008764 nerve damage Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 231100000189 neurotoxic Toxicity 0.000 abstract 1
- 230000002887 neurotoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13951793A | 1993-10-18 | 1993-10-18 | |
| PCT/US1994/011567 WO1995011016A1 (en) | 1993-10-18 | 1994-10-12 | R-enantiomer of n-propargyl-1-aminoindan, salts, compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL300205I1 NL300205I1 (nl) | 2005-10-03 |
| NL300205I2 true NL300205I2 (nl) | 2006-03-01 |
Family
ID=22487049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL300205C NL300205I2 (nl) | 1993-10-18 | 2005-08-15 | N-enentiomeer van N-propargyl-1-aminoindaan voor de behandeling van |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0812190B1 (enExample) |
| JP (3) | JPH09505806A (enExample) |
| AT (1) | ATE284208T1 (enExample) |
| AU (1) | AU1253495A (enExample) |
| CA (1) | CA2174449C (enExample) |
| DE (2) | DE69434178T2 (enExample) |
| DK (1) | DK0812190T3 (enExample) |
| ES (1) | ES2235170T3 (enExample) |
| FR (1) | FR05C0033I2 (enExample) |
| HU (1) | HU226138B1 (enExample) |
| IL (1) | IL111240A (enExample) |
| LU (1) | LU91191I2 (enExample) |
| MX (1) | MXPA94008019A (enExample) |
| NL (1) | NL300205I2 (enExample) |
| PT (1) | PT812190E (enExample) |
| WO (1) | WO1995011016A1 (enExample) |
| ZA (1) | ZA948013B (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744500A (en) | 1990-01-03 | 1998-04-28 | Teva Pharmaceutical Industries, Ltd. | Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof |
| US5844003A (en) * | 1991-04-04 | 1998-12-01 | Innovations Foundation | Use of deprenyl compounds to maintain, prevent loss, or recover nerve cell function |
| DE4327516A1 (de) * | 1993-08-17 | 1995-02-23 | Asta Medica Ag | Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin |
| WO1995018617A1 (en) * | 1994-01-10 | 1995-07-13 | Teva Pharmaceutical Industries Ltd. | 1-aminoindan derivatives and compositions thereof |
| US5914349A (en) | 1994-01-10 | 1999-06-22 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
| EP0808160A1 (en) * | 1995-02-10 | 1997-11-26 | The University Of Toronto Innovations Foundation | Deprenyl compounds for treatment of glaucoma |
| PT814789E (pt) * | 1995-03-02 | 2003-09-30 | Scherer Technologies Inc R P | Composicoes farmaceuticas compreendendo inibidores de monoamina-oxidase b |
| IL115357A (en) * | 1995-09-20 | 2000-01-31 | Teva Pharma | Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols |
| IL118836A (en) * | 1996-07-11 | 2001-01-11 | Teva Pharma | Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan |
| IL119417A (en) * | 1996-10-13 | 2003-02-12 | Moshe Kushnir | Pharmaceutical composition for transdermal administration of levodopa for parkinson's disease |
| ATE292619T1 (de) | 1996-12-18 | 2005-04-15 | Teva Pharma | Aminoindanderivate |
| GB9715082D0 (en) * | 1997-07-17 | 1997-09-24 | Scherer Ltd R P | Treatment of attention deficit hyperactivity disorder and narcolepsy |
| WO1999037293A2 (en) * | 1998-01-27 | 1999-07-29 | Thomas Thomas N | Use of an mao-a or mao-b inhibitor for the treatment of vascular disorders |
| US6737547B1 (en) | 1998-12-31 | 2004-05-18 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using N-acyl-1H-aminoindenes |
| AU775885B2 (en) | 1999-10-27 | 2004-08-19 | Teva Pharmaceutical Industries Ltd. | Use of 1-aminoindan derivatives for treatment of mania in bipolar mood disorder |
| ES2588780T3 (es) * | 2002-11-15 | 2016-11-04 | Teva Pharmaceutical Industries Limited | Uso de rasagilina con o sin riluzol para el tratamiento de la esclerosis lateral amiotrófica |
| AR044007A1 (es) * | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
| EP1588704A1 (en) * | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
| JP5738509B2 (ja) * | 2005-02-23 | 2015-06-24 | テバ ファーマシューティカル インダストリーズ リミティド | 内容物均一性が改善されたラサギリン製剤 |
| CN101622225B (zh) * | 2005-11-17 | 2015-04-15 | 泰华制药工业有限公司 | 炔丙基氨基茚分离方法 |
| US7572834B1 (en) | 2005-12-06 | 2009-08-11 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations and processes for their preparation |
| CN101325871B (zh) | 2005-12-09 | 2013-04-10 | 耶路撒冷希伯来大学伊森姆研究发展公司 | 低剂量Ladostigil用于神经保护的用途 |
| CA2643235C (en) * | 2006-02-21 | 2014-06-17 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of multiple system atrophy |
| TW200744576A (en) | 2006-02-24 | 2007-12-16 | Teva Pharma | Propargylated aminoindans, processes for preparation, and uses thereof |
| JP5769923B2 (ja) | 2006-04-03 | 2015-08-26 | テバ ファーマシューティカル インダストリーズ リミティド | レストレスレッグス症候群の治療のためのラサギリンの使用 |
| EP1892233A1 (de) * | 2006-08-18 | 2008-02-27 | Ratiopharm GmbH | Neue Salze des Wirkstoffs Rasagilin |
| DK2101569T3 (da) | 2006-12-14 | 2012-01-30 | Teva Pharma | Krystallinsk fast rasagilinbase |
| BRPI0718339A2 (pt) | 2006-12-14 | 2014-02-18 | Teva Pharma | Composto, composição, composição farmacêutica e processo de fabricação de tanato de rasagilina |
| EP2194780A4 (en) * | 2007-09-05 | 2010-10-27 | Teva Pharma | METHOD FOR TREATING GLAUCOMA BY RASAGILINE |
| US8461388B2 (en) | 2007-12-24 | 2013-06-11 | Cipla Limited | Process for the synthesis of propargylated aminoindan derivatives |
| US20110117200A1 (en) * | 2008-03-31 | 2011-05-19 | Actavis Group Ptc Ehf | Rasagiline mesylate particles and process for the preparation thereof |
| WO2009141737A2 (en) | 2008-05-23 | 2009-11-26 | Medichem, S.A. | A new method for obtaining an aminoindan mesylate derivative |
| AU2009254929B2 (en) * | 2008-06-02 | 2014-03-13 | Generics [Uk] Limited | An improved process for the preparation of amines |
| US8569545B2 (en) * | 2008-06-02 | 2013-10-29 | Generics (Uk) Limited | Process for the preparation of enantiomerically pure amines |
| EP2299993A4 (en) * | 2008-06-19 | 2014-08-20 | Teva Pharma | PROCESS FOR PURIFYING THE BASE OF RASAGILINE |
| US20100010098A1 (en) | 2008-07-11 | 2010-01-14 | Walter Elffrink | Polymorphs of rasagiline hydrochloride |
| US20100041920A1 (en) * | 2008-07-18 | 2010-02-18 | Stephen Benedict David Winter | New salt forms of an aminoindan derivative |
| DE102008064061A1 (de) | 2008-12-19 | 2010-06-24 | Ratiopharm Gmbh | Feste Zusammensetzung mit dem Wirkstoff Rasagilin |
| US8080584B2 (en) | 2009-01-23 | 2011-12-20 | Teva Pharmaceuticals Industries, Ltd. | Delayed release rasagiline citrate formulation |
| PL2451771T3 (pl) | 2009-07-09 | 2014-12-31 | Ratiopharm Gmbh | Sole rasagiliny i ich preparaty farmaceutyczne |
| CN102048717B (zh) † | 2009-10-29 | 2014-02-19 | 重庆医药工业研究院有限责任公司 | 一种稳定的雷沙吉兰组合物 |
| EP2325159A1 (en) | 2009-11-24 | 2011-05-25 | LEK Pharmaceuticals d.d. | Novel salts of rasagiline |
| WO2011087791A1 (en) | 2009-12-22 | 2011-07-21 | Teva Pharmaceutical Industries Ltd. | 3-keto-n-propargyl-1-aminoindan |
| WO2011080589A2 (en) * | 2009-12-30 | 2011-07-07 | Actavis Group Ptc Ehf | Solid state forms of rasagiline salts |
| EP3517103A1 (en) * | 2010-02-03 | 2019-07-31 | Pharma Two B Ltd. | Extended release formulations of rasagiline and uses thereof |
| WO2011121607A2 (en) | 2010-03-29 | 2011-10-06 | Cadila Healthcare Limited | Rasagiline and its pharmaceutically acceptable salts |
| EP2389927A1 (en) | 2010-05-30 | 2011-11-30 | Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi | Pharmaceutical formulations of rasagiline |
| CN102464589A (zh) * | 2010-11-17 | 2012-05-23 | 凯瑞斯德生化(苏州)有限公司 | 雷沙吉兰、其甲磺酸盐及其中间体的制备方法 |
| EP2663545B1 (en) | 2011-01-13 | 2015-07-01 | Nobel Ilaç Sanayii Ve Ticaret A.S. | A new method for the synthesis of rasagiline |
| EP2681186B1 (en) | 2011-03-03 | 2016-05-11 | Synthon BV | Process of resolution of 1-aminoindan |
| EP2705021A2 (en) | 2011-05-04 | 2014-03-12 | Cadila Healthcare Limited | Rasagiline and its pharmaceutically acceptable salts |
| KR20140090996A (ko) * | 2011-10-10 | 2014-07-18 | 테바 파마슈티컬 인더스트리즈 리미티드 | R(+)-n-폼일-프로파길-아미노인단 |
| DE102012000786A1 (de) | 2012-01-18 | 2013-07-18 | Stada Arzneimittel Ag | Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung, enthaltend den Wirkstoff Rasagilin |
| WO2013139387A1 (en) | 2012-03-21 | 2013-09-26 | Synthon Bv | Stabilized pharmaceutical compositions comprising rasagiline salts |
| WO2013175493A1 (en) | 2012-04-09 | 2013-11-28 | Cadila Healthcare Limited | Stable oral pharmaceutical compositions |
| ES2524865T1 (es) | 2013-02-06 | 2014-12-15 | Galenicum Health S.L. | Composiciones farmacéuticas estables en forma de comprimidos de liberación inmediata |
| ES2502140T1 (es) | 2013-02-06 | 2014-10-02 | Galenicum Health S.L. | Comprimidos de liberación inmediata de rasagilina hemitartrato |
| WO2014192022A1 (en) * | 2013-05-20 | 2014-12-04 | Cadila Healthcare Limited | Pharmaceutical compositions of rasagiline |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1187017A (en) * | 1966-07-16 | 1970-04-08 | Aspro Nicholas Ltd | Substituted 1-Amino Indanes and Tetrahydronaphthalens |
| DE252290T1 (de) * | 1986-06-10 | 1988-06-09 | Chiesi Farmaceutici S.P.A., Parma | Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen. |
| IL92952A (en) * | 1990-01-03 | 1994-06-24 | Teva Pharma | R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them |
| IL112819A (en) * | 1991-10-16 | 2001-11-25 | Teva Pharma | Fluorinated 1-aminoindan compounds and a process for their preparation |
-
1994
- 1994-10-11 IL IL11124094A patent/IL111240A/en not_active IP Right Cessation
- 1994-10-12 AT AT95903505T patent/ATE284208T1/de active
- 1994-10-12 ES ES95903505T patent/ES2235170T3/es not_active Expired - Lifetime
- 1994-10-12 CA CA002174449A patent/CA2174449C/en not_active Expired - Lifetime
- 1994-10-12 PT PT95903505T patent/PT812190E/pt unknown
- 1994-10-12 DE DE69434178T patent/DE69434178T2/de not_active Expired - Lifetime
- 1994-10-12 WO PCT/US1994/011567 patent/WO1995011016A1/en not_active Ceased
- 1994-10-12 JP JP7512014A patent/JPH09505806A/ja not_active Withdrawn
- 1994-10-12 AU AU12534/95A patent/AU1253495A/en not_active Abandoned
- 1994-10-12 HU HU9601012A patent/HU226138B1/hu active Protection Beyond IP Right Term
- 1994-10-12 DK DK95903505T patent/DK0812190T3/da active
- 1994-10-12 EP EP95903505A patent/EP0812190B1/en not_active Expired - Lifetime
- 1994-10-12 DE DE200512000044 patent/DE122005000044I2/de active Active
- 1994-10-13 ZA ZA948013A patent/ZA948013B/xx unknown
- 1994-10-17 MX MXPA94008019A patent/MXPA94008019A/es active IP Right Grant
-
2002
- 2002-10-17 JP JP2002303097A patent/JP2003160481A/ja not_active Withdrawn
-
2005
- 2005-08-09 FR FR05C0033C patent/FR05C0033I2/fr active Active
- 2005-08-10 LU LU91191C patent/LU91191I2/fr unknown
- 2005-08-15 NL NL300205C patent/NL300205I2/nl unknown
-
2009
- 2009-09-24 JP JP2009219662A patent/JP2010018626A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0812190A4 (en) | 1998-03-04 |
| IL111240A0 (en) | 1994-12-29 |
| IL111240A (en) | 2001-10-31 |
| ZA948013B (en) | 1995-05-31 |
| AU1253495A (en) | 1995-05-08 |
| DE122005000044I1 (de) | 2005-12-22 |
| ES2235170T3 (es) | 2005-07-01 |
| DK0812190T3 (da) | 2005-04-11 |
| LU91191I2 (fr) | 2005-10-10 |
| NL300205I1 (nl) | 2005-10-03 |
| JPH09505806A (ja) | 1997-06-10 |
| WO1995011016A1 (en) | 1995-04-27 |
| JP2010018626A (ja) | 2010-01-28 |
| EP0812190B1 (en) | 2004-12-08 |
| DE69434178T2 (de) | 2005-12-01 |
| DE122005000044I2 (de) | 2007-09-13 |
| ATE284208T1 (de) | 2004-12-15 |
| FR05C0033I2 (fr) | 2006-12-29 |
| DE69434178D1 (de) | 2005-01-13 |
| MXPA94008019A (es) | 2004-08-10 |
| HU226138B1 (en) | 2008-05-28 |
| PT812190E (pt) | 2005-04-29 |
| JP2003160481A (ja) | 2003-06-03 |
| CA2174449A1 (en) | 1995-04-27 |
| CA2174449C (en) | 2007-01-16 |
| FR05C0033I1 (enExample) | 2005-09-30 |
| HU9601012D0 (en) | 1996-06-28 |
| HUT77934A (hu) | 1998-11-30 |
| EP0812190A1 (en) | 1997-12-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL300205I2 (nl) | N-enentiomeer van N-propargyl-1-aminoindaan voor de behandeling van | |
| MX9708977A (es) | Uso de r-enantiomero de sales de n-propargilo-1-aminoindano, y composiciones de las mismas. | |
| ATE328590T1 (de) | Pharmazeutische zusammensetzungen enthaltend s-(- )-n-propargyl-1-aminoindan | |
| TW264480B (enExample) | ||
| AU2001273574A1 (en) | Substituted 5-alkynyl pyrimidines having neurotrophic activity | |
| IL225192A (en) | Combinations of dextromethorphan and quinidine for the preparation of mental illness, neuropathic pain or brain injury | |
| BG104686A (en) | Glycine transport inhibitors | |
| AU4333893A (en) | Use of guanosine and its precursors and derivatives in the manufacture of drugs for the treatment of brain dysfunction | |
| AU3585089A (en) | Condensed diazepinones | |
| IL101560A0 (en) | Condensed diazepinones,their preparation and pharmaceutical compositions containing them |