RU96105707A - Лекарственное средство для лечения дегенеративных заболеваний нервной системы - Google Patents
Лекарственное средство для лечения дегенеративных заболеваний нервной системыInfo
- Publication number
- RU96105707A RU96105707A RU96105707/14A RU96105707A RU96105707A RU 96105707 A RU96105707 A RU 96105707A RU 96105707/14 A RU96105707/14 A RU 96105707/14A RU 96105707 A RU96105707 A RU 96105707A RU 96105707 A RU96105707 A RU 96105707A
- Authority
- RU
- Russia
- Prior art keywords
- treatment
- flupirtine
- drugs
- preparation
- disease
- Prior art date
Links
- 230000003412 degenerative Effects 0.000 title claims 2
- 201000010099 disease Diseases 0.000 title 1
- 210000000653 nervous system Anatomy 0.000 title 1
- JUUFBMODXQKSTD-UHFFFAOYSA-N Flupirtine Chemical compound N1=C(N)C(NC(=O)OCC)=CC=C1NCC1=CC=C(F)C=C1 JUUFBMODXQKSTD-UHFFFAOYSA-N 0.000 claims 12
- 239000003814 drug Substances 0.000 claims 12
- 229940079593 drugs Drugs 0.000 claims 12
- 229960003667 flupirtine Drugs 0.000 claims 12
- 206010053643 Neurodegenerative disease Diseases 0.000 claims 3
- 206010061536 Parkinson's disease Diseases 0.000 claims 3
- 201000010874 syndrome Diseases 0.000 claims 2
- 206010001897 Alzheimer's disease Diseases 0.000 claims 1
- 206010002026 Amyotrophic lateral sclerosis Diseases 0.000 claims 1
- 208000001183 Brain Injury Diseases 0.000 claims 1
- 206010008120 Cerebral ischaemia Diseases 0.000 claims 1
- 201000001971 Huntington's disease Diseases 0.000 claims 1
- 206010022998 Irritability Diseases 0.000 claims 1
- 210000001428 Peripheral Nervous System Anatomy 0.000 claims 1
- 210000001525 Retina Anatomy 0.000 claims 1
- 231100001018 bone marrow damage Toxicity 0.000 claims 1
- 201000006474 brain ischemia Diseases 0.000 claims 1
- 230000002490 cerebral Effects 0.000 claims 1
- 230000002458 infectious Effects 0.000 claims 1
- 230000000302 ischemic Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 230000000626 neurodegenerative Effects 0.000 claims 1
Claims (1)
1. Применение флюпиртина для приготовления препаратов для лечения церебральной ишемии.
2. Применение флюпиртина для приготовления препаратов для лечения нейродегенеративных заболеваний, за исключением болезни Паркинсона.
3. Применение флюпиртина для приготовления препаратов для лечения болезни Альцгеймера.
4. Применение флюпиртина для приготовления препаратов для лечения хореи Гентингтона.
5. Применение флюпиртина для приготовления препаратов для лечения множественного склероза.
6. Применение флюпиртина для приготовления препаратов для лечения амиотрофического латерального склероза.
7. Применение флюпиртина для приготовления препаратов для лечения нейродегенеративных расстройств инфекционного генеза, за исключением болезни Паркинсона.
8. Применение флюпиртина для приготовления препаратов для лечения метаболическо-токсических нейродегенеративных расстройств, за исключением болезни Паркинсона.
9. Применение флюпиртина для приготовления препаратов для лечения дегенеративных и ишемических процессов в сетчатке.
10. Применение флюпиртина для приготовления препаратов для лечения травм головного мозга и повреждений костного мозга
11. Применение флюпиртина для приготовления препаратов для лечения синдромов повышенной церебральной возбудимости.
11. Применение флюпиртина для приготовления препаратов для лечения синдромов повышенной церебральной возбудимости.
12. Применение флюпиртина для приготовления препаратов для лечения нейродегенеративных синдромов периферической нервной системы.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP4327516.8 | 1993-08-17 | ||
| DE4327516A DE4327516A1 (de) | 1993-08-17 | 1993-08-17 | Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU96105707A true RU96105707A (ru) | 1998-06-10 |
| RU2166318C2 RU2166318C2 (ru) | 2001-05-10 |
Family
ID=6495312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU96105707/14A RU2166318C2 (ru) | 1993-08-17 | 1994-08-10 | Флюпиртин - действующее вещество медицинских и фармакологических средств с активностью антагониста эксайторных аминокислот |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5721258A (ru) |
| EP (1) | EP0716602B1 (ru) |
| JP (1) | JPH09501664A (ru) |
| KR (1) | KR100341952B1 (ru) |
| CN (1) | CN1086291C (ru) |
| AT (1) | ATE210442T1 (ru) |
| AU (1) | AU694447B2 (ru) |
| BG (1) | BG62430B1 (ru) |
| BR (1) | BR9407293A (ru) |
| CA (1) | CA2169718C (ru) |
| CZ (1) | CZ289040B6 (ru) |
| DE (2) | DE4327516A1 (ru) |
| DK (1) | DK0716602T3 (ru) |
| EE (1) | EE03204B1 (ru) |
| ES (1) | ES2168309T3 (ru) |
| HR (1) | HRP940464A2 (ru) |
| HU (1) | HU227765B1 (ru) |
| IL (1) | IL110681A (ru) |
| NO (1) | NO309842B1 (ru) |
| NZ (1) | NZ273292A (ru) |
| PT (1) | PT716602E (ru) |
| RU (1) | RU2166318C2 (ru) |
| SK (1) | SK283330B6 (ru) |
| UA (1) | UA43351C2 (ru) |
| WO (1) | WO1995005175A1 (ru) |
| YU (1) | YU49215B (ru) |
| ZA (1) | ZA946176B (ru) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19539861A1 (de) * | 1995-10-26 | 1997-04-30 | Asta Medica Ag | Verwendung von 4-Amino-4-(4-fluorbenzylamino)-1-ethoxy-carbonylaminobenzen zur Prophylaxe und Behandlung der Folgen der akuten und chronischen zerebralen Minderdurchblutung sowie neurodegenerativer Erkrankungen |
| DE19541405A1 (de) * | 1995-11-07 | 1997-05-15 | Asta Medica Ag | Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen |
| DE19625582A1 (de) * | 1996-06-27 | 1998-01-02 | Asta Medica Ag | Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen die mit einer unphysiologisch hohen Zellsterberate einhergehen |
| CN1278167A (zh) | 1997-10-27 | 2000-12-27 | 住友制药株式会社 | 酰胺衍生物 |
| WO2001034172A2 (en) * | 1999-11-05 | 2001-05-17 | Vela Pharmaceuticals Inc. | Methods and compositions for treating reward deficiency syndrome |
| US6821995B1 (en) | 1999-12-01 | 2004-11-23 | Duke University | Method of treating batten disease |
| WO2001039760A2 (en) * | 1999-12-01 | 2001-06-07 | Duke University | Method of treating batten disease |
| DE10327674A1 (de) * | 2003-06-20 | 2005-01-05 | Awd.Pharma Gmbh & Co. Kg | Injizierbare Darreichungsform von Flupirtin |
| DE10328260A1 (de) * | 2003-06-23 | 2005-01-27 | Schmidt, K.-G., Dr. med. | Flupirtine-Präparat |
| WO2005058319A1 (en) * | 2003-12-16 | 2005-06-30 | Cnsbio Pty Ltd | Methods and compositions |
| EP1831170A4 (en) * | 2004-12-14 | 2009-10-14 | Astrazeneca Ab | SUBSTITUTED AMINOPYRIDINES AND THEIR USE |
| EP1688141A1 (en) | 2005-01-31 | 2006-08-09 | elbion AG | The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome |
| US20060258708A1 (en) * | 2005-05-16 | 2006-11-16 | Andrulis Peter J Jr | Method for treating Parkinson's disease and other neurological diseases |
| US20080279930A1 (en) * | 2007-05-07 | 2008-11-13 | Bernd Terhaag | Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof |
| DE102011006425A1 (de) | 2010-03-31 | 2011-10-06 | Awd.Pharma Gmbh & Co. Kg | Pharmazeutische Zubereitung und deren Verwendung |
| DE102010030053A1 (de) | 2010-06-14 | 2011-12-15 | Awd.Pharma Gmbh & Co.Kg | Injizierbare Darreichungsform von Flupirtin |
| EP3027188A4 (en) * | 2013-07-31 | 2017-03-01 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with combination of laquinimod and flupirtine |
| US11369593B2 (en) * | 2017-07-14 | 2022-06-28 | Texas Tech University System | Functionalized pyridine carbamates with enhanced neuroprotective activity |
| DE102017007385A1 (de) | 2017-08-02 | 2019-02-07 | Christoph Hoock | Maleatfreie feste Arzneimittelformen |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4481205A (en) * | 1980-09-13 | 1984-11-06 | Degussa Aktiengesellschaft | 2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate |
| DE3369315D1 (en) * | 1982-10-27 | 1987-02-26 | Degussa | Derivatives of 2-amino-3-acylamino-6-benzylamino pyridine with an anti-epileptic activity |
| DE3337593A1 (de) * | 1982-10-27 | 1984-05-03 | Degussa Ag, 6000 Frankfurt | 2-amino-3-acylamino-6-benzylamino-pyridin-derivate mit antiepileptischer wirkung |
| NO860825L (no) * | 1985-03-23 | 1986-09-24 | Degussa | Fremgangsmaate til fremstilling av 2-amino-3-nitro-6-(4-fluor-benzylamino)-pyridin samt 2-amino-3-karbetoksyamino-6-(4-fluor-benzylamino)-pyridin. |
| IN172468B (ru) * | 1990-07-14 | 1993-08-14 | Asta Medica Ag |
-
1993
- 1993-08-17 DE DE4327516A patent/DE4327516A1/de not_active Ceased
-
1994
- 1994-08-10 WO PCT/EP1994/002649 patent/WO1995005175A1/en active IP Right Grant
- 1994-08-10 CZ CZ1996465A patent/CZ289040B6/cs not_active IP Right Cessation
- 1994-08-10 DK DK94926828T patent/DK0716602T3/da active
- 1994-08-10 DE DE69429435T patent/DE69429435T2/de not_active Expired - Lifetime
- 1994-08-10 JP JP7506731A patent/JPH09501664A/ja active Pending
- 1994-08-10 AT AT94926828T patent/ATE210442T1/de active
- 1994-08-10 PT PT94926828T patent/PT716602E/pt unknown
- 1994-08-10 BR BR9407293A patent/BR9407293A/pt not_active Application Discontinuation
- 1994-08-10 CA CA002169718A patent/CA2169718C/en not_active Expired - Lifetime
- 1994-08-10 SK SK214-96A patent/SK283330B6/sk not_active IP Right Cessation
- 1994-08-10 HU HU9600355A patent/HU227765B1/hu unknown
- 1994-08-10 ES ES94926828T patent/ES2168309T3/es not_active Expired - Lifetime
- 1994-08-10 US US08/602,742 patent/US5721258A/en not_active Expired - Lifetime
- 1994-08-10 EP EP94926828A patent/EP0716602B1/en not_active Expired - Lifetime
- 1994-08-10 RU RU96105707/14A patent/RU2166318C2/ru active
- 1994-08-10 KR KR1019960700753A patent/KR100341952B1/ko active IP Right Grant
- 1994-08-10 NZ NZ273292A patent/NZ273292A/en not_active IP Right Cessation
- 1994-08-10 CN CN94193106A patent/CN1086291C/zh not_active Expired - Lifetime
- 1994-08-10 AU AU76528/94A patent/AU694447B2/en not_active Expired
- 1994-08-15 YU YU51294A patent/YU49215B/sh unknown
- 1994-08-16 HR HRP4327516.8A patent/HRP940464A2/hr not_active Application Discontinuation
- 1994-08-16 ZA ZA946176A patent/ZA946176B/xx unknown
- 1994-08-16 IL IL11068194A patent/IL110681A/xx not_active IP Right Cessation
- 1994-10-08 UA UA96030972A patent/UA43351C2/uk unknown
- 1994-10-25 EE EE9400160A patent/EE03204B1/xx unknown
-
1996
- 1996-02-14 BG BG100356A patent/BG62430B1/bg unknown
- 1996-02-15 NO NO960607A patent/NO309842B1/no not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU96105707A (ru) | Лекарственное средство для лечения дегенеративных заболеваний нервной системы | |
| CA2260037A1 (en) | Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan | |
| WO1996037199A8 (en) | Use of r-enantiomer of n-propargyl-1-aminoindan, salts, and compositions thereof | |
| NL300205I1 (nl) | N-enentiomeer van N-propargyl-1-aminoindaan voor de behandeling van verschillende ziekten, en mesylaat, esylaat en sulfaat daarvan. | |
| CA2050284A1 (en) | PCP Receptor Ligands and the Use Thereof | |
| BR9707616A (pt) | Composto composiç o farmacéutica utilização de um composto e processo para a preparação de um composto para o tratamento ou profilaxia de distúrbios de deficiéncia intelectual ou profilaxia da doença de parkinson doença de huntington síndrome de tourette esclerose amiotrófica lateral ou distúrbios neurodegenerativos | |
| HUP9802862A2 (hu) | (1S,2S)-1-(4-hydroxi-fenil)-2-(4-hidroxi-4-fenil-1-piperidinil)-1-propanol-metánszulfonát-trihidrát, és ezt a vegyületet tartalmazó a központi idegrendszeri rendellenességek kezelésére alkalmas gyógyászati készítmények | |
| ZA901854B (en) | Pharmaceutical product for the treatment of immunoregulatory disorders | |
| BR9203032A (pt) | Material esponjoso de liberacao lenta,processo para preparar o mesmo,preparacoes farmaceuticas e processo terapeutico | |
| BG104686A (en) | Glycine transport inhibitors | |
| RU94012366A (ru) | Производные 2-(4-гидроксипиридино)-1-алканола, способ получения, промежуточный продукт, фармацевтическая композиция, способ лечения | |
| KR960703591A (ko) | 신경변성 질병에서 플로피르틴의 일차적 및 이차적 신경보호 효과(The primary and secondary neuroprotective effect of flupirtine in neurodegenerative diseases) | |
| AU7425391A (en) | Use of n-alkylated 1, 4-dihydropyridinedicarboxylic acid esters as medicaments, new compounds and processes for their preparation | |
| EP0267676A3 (en) | Use of 1,3-di-n-butyl-7-(2-oxypropyl) xanthine in the treatment of cerebrovascular or cerebral senility associated disorders, peripheral vascular disease and proliferative skin diseases | |
| AU5053296A (en) | Pharmaceutical agents for the treatment of Alzheimer's disease | |
| MA22866A1 (fr) | Procede pour la preparation des composes pour le traitement des troubles neuro-degeneratifs . | |
| MX9200948A (es) | Composicion farmaceutica para el tratamiento de isquemia cerebral en mamiferos. | |
| CA2374997A1 (en) | Il6ril6 chimera for the treatment of neurodegenerative diseases | |
| TH20134EX (th) | ผลการป้องกันระบบประสาทแบบปฐมภูมิและทุติยภูมิของฟลูเพอร์ทีน ในโรคการเสื่อมของระบบประสาท | |
| CA2135752A1 (en) | Use of (E)-2-(p-Fluorophenethyl)-3-Fluoroallylamine in the Treatment of Alzheimer's Disease | |
| GB9209599D0 (en) | Novel therapy for the treatment of parkinsons disease | |
| Manabe | Does Aluminum Cause Alzheimer's Disease? | |
| Smith | A description of the events which influence spouse caregivers of Alzheimer's disease clients to seek support | |
| AU6035490A (en) | Medicament against degenerative brain performance diseases of the alzheimer type and cholinergic system disturbances |