NL222157A - - Google Patents
Info
- Publication number
- NL222157A NL222157A NL222157DA NL222157A NL 222157 A NL222157 A NL 222157A NL 222157D A NL222157D A NL 222157DA NL 222157 A NL222157 A NL 222157A
- Authority
- NL
- Netherlands
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657154—Cyclic esteramides of oxyacids of phosphorus
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEA26234A DE1054997B (de) | 1956-12-20 | 1956-12-20 | Verfahren zur Herstellung von cyclischen Thiophosphorsaeure-esteramiden |
| DEA28444A DE1116672B (de) | 1956-12-20 | 1957-12-04 | Verfahren zur Herstellung von cyclischen Phosphorsaeure- und Thiophosphorsaeureesteramiden |
| DEA24298A DE1057119B (de) | 1956-12-20 | 1957-12-04 | Verfahren zur Herstellung von cyclischen Phosphorsaeure-esteramiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL222157A true NL222157A (ja) |
Family
ID=27208860
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL222157D NL222157A (ja) | 1956-12-20 | ||
| NL99688D NL99688C (ja) | 1956-12-20 | ||
| NL99649D NL99649C (ja) | 1956-12-20 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL99688D NL99688C (ja) | 1956-12-20 | ||
| NL99649D NL99649C (ja) | 1956-12-20 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US3018302A (ja) |
| BE (2) | BE554888A (ja) |
| CH (3) | CH361279A (ja) |
| DE (3) | DE1054997B (ja) |
| FR (2) | FR1246708A (ja) |
| GB (2) | GB812651A (ja) |
| NL (3) | NL99649C (ja) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270093A (en) * | 1963-04-19 | 1966-08-30 | Tenneco Chem | Omicron, omicron-neopentylene-nu-diethylphosphoroamidothioate |
| US3286001A (en) * | 1963-06-07 | 1966-11-15 | Continental Oil Co | Reaction products of organophosphorus monohalides with mercaptoalkylamines |
| US3335129A (en) * | 1963-11-21 | 1967-08-08 | Wyandotte Chemicals Corp | Phosphoramidates |
| DE2110333A1 (de) * | 1971-03-04 | 1972-09-14 | Audi Nsu Auto Union Ag | Kreiskolben-Brennkraftmaschine |
| PL100390B1 (pl) | 1975-10-06 | 1978-09-30 | Sposob wytwarzania 2-tlenku-2-/bis/2-chloroetylo/-amino/-1-/okso-3-aza-2-fosfacykloheksanu/cyklofosfamidu/o czynnosci optycznej | |
| DE3132221A1 (de) * | 1981-08-14 | 1983-05-19 | Behringwerke Ag, 3550 Marburg | Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung |
| DE3133077A1 (de) * | 1981-08-21 | 1983-03-10 | Henkel KGaA, 4000 Düsseldorf | Neue cytostatisch wirksame epoxidgruppen tragende 1,3,2-oxazaphosphorin-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung in pharmazeutischen zubereitungen |
| US4537883A (en) * | 1982-11-12 | 1985-08-27 | Mead Johnson & Company | Lyophilized cyclophosphamide |
| US5227374A (en) * | 1982-11-12 | 1993-07-13 | Mead Johnson & Company | Lyophilized cyclophosphamide |
| US4659699A (en) * | 1983-08-22 | 1987-04-21 | Cetus-Ben Venue Therapeutics | Process for freeze drying cyclophosphamide |
| US4879286A (en) * | 1987-01-28 | 1989-11-07 | Lyphomed, Inc. | Cyclophosphamide |
| IT1251472B (it) * | 1991-09-12 | 1995-05-15 | Boehringer Mannheim Italia | Ossaazafosforine utili come agenti antitumorali, un processo per la loro preparazione e composizioni farmaceutiche che le contengono |
| DE19739159C1 (de) * | 1997-09-06 | 1999-01-28 | Asta Medica Ag | Verfahren zur Herstellung von Oxazaphosphorin-2-aminen |
| US6312662B1 (en) * | 1998-03-06 | 2001-11-06 | Metabasis Therapeutics, Inc. | Prodrugs phosphorus-containing compounds |
| AU767599B2 (en) | 1998-03-06 | 2003-11-20 | Metabasis Therapeutics, Inc. | Novel prodrugs for phosphorus-containing compounds |
| US7205404B1 (en) | 1999-03-05 | 2007-04-17 | Metabasis Therapeutics, Inc. | Phosphorus-containing prodrugs |
| WO2000052015A2 (en) * | 1999-03-05 | 2000-09-08 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing prodrugs |
| JP4979866B2 (ja) | 1999-09-08 | 2012-07-18 | リガンド・ファーマシューティカルズ・インコーポレイテッド | 肝臓に特異的なドラッグデリバリーのためのプロドラッグ |
| US7829084B2 (en) | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| NZ536328A (en) * | 2002-05-13 | 2007-11-30 | Metabasis Therapeutics Inc | Novel phosphonic acid based prodrugs of PMEA and its analogues |
| EP1504014B1 (en) * | 2002-05-13 | 2015-12-02 | Metabasis Therapeutics, Inc. | Process for preparation of cyclic prodrugs of pmea and pmpa |
| MXPA05004503A (es) * | 2002-10-31 | 2005-08-16 | Metabasis Therapeutics Inc | Nuevos profarmacos de monofosfato de citarabina. |
| US20050182252A1 (en) * | 2004-02-13 | 2005-08-18 | Reddy K. R. | Novel 2'-C-methyl nucleoside derivatives |
| RU2006138907A (ru) * | 2004-06-08 | 2008-07-20 | Метабазис Терапеутикс | Синтез сложных циклических эфиров с применением кислоты льюиса |
| JP2017512183A (ja) * | 2014-02-13 | 2017-05-18 | リガンド・ファーマシューティカルズ・インコーポレイテッド | プロドラッグ化合物およびそれらの使用 |
| BR112016026140A2 (pt) | 2014-05-09 | 2018-08-07 | AuroMedics Pharma LLC | formulações de concentrado líquido de ciclofosfamida. |
| CN106687118A (zh) | 2014-07-02 | 2017-05-17 | 配体药物公司 | 前药化合物及其用途 |
| WO2016005962A2 (en) | 2014-07-11 | 2016-01-14 | Dr. Reddy’S Laboratories Limited | Stable liquid formulations of cyclophosphamide and processes |
| US10849916B2 (en) | 2014-07-11 | 2020-12-01 | Dr. Reddys Laboratories Limited | Stable liquid formulations of cyclophosphamide and its impurities |
| WO2016046797A1 (en) | 2014-09-26 | 2016-03-31 | Intas Pharmaceuticals Ltd. | Pharmaceutical composition having improved content uniformity |
| CA2972065A1 (en) | 2014-12-23 | 2016-06-30 | Intellectual Property Associates, Llc | Methods and formulations for transdermal administration |
| WO2016156927A1 (en) | 2015-04-02 | 2016-10-06 | PRZEDSIĘBIORSTWO PRODUKCYJNO-WDROŻENIOWE IFOTAM Sp. z o.o. | Method of production of n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxazaphosphorine-2-amine 2-oxide |
| WO2017207719A1 (en) | 2016-06-02 | 2017-12-07 | Amneal Pharmaceuticals Company Gmbh | Cyclophosphamide composition and method for preparation thereof |
| US20190083386A1 (en) | 2017-09-15 | 2019-03-21 | Ampersand Biopharmaceuticals, Inc. | Methods and formulations for transdermal administration of buffering agents |
| US11970482B2 (en) | 2018-01-09 | 2024-04-30 | Ligand Pharmaceuticals Inc. | Acetal compounds and therapeutic uses thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1065418B (de) * | 1953-03-21 | 1959-09-17 | Montecatini Soc. Gen. per 1'Industria Mineraria e Chimica, Mailand (Italien) | Verfahren zur Herstellung von heterocyclischen Phosphorverbindungen |
| NL236264A (ja) * | 1958-02-20 | 1900-01-01 |
-
0
- FR FR75178D patent/FR75178E/fr not_active Expired
- NL NL222157D patent/NL222157A/xx unknown
- BE BE563332D patent/BE563332A/xx unknown
- NL NL99688D patent/NL99688C/xx active
- NL NL99649D patent/NL99649C/xx active
- BE BE554888D patent/BE554888A/xx unknown
-
1956
- 1956-12-20 DE DEA26234A patent/DE1054997B/de active Pending
-
1957
- 1957-01-30 GB GB3283/57A patent/GB812651A/en not_active Expired
- 1957-02-04 FR FR731011A patent/FR1246708A/fr not_active Expired
- 1957-02-09 CH CH361279D patent/CH361279A/de unknown
- 1957-11-28 CH CH5317357A patent/CH369451A/de unknown
- 1957-12-04 DE DEA24298A patent/DE1057119B/de active Pending
- 1957-12-04 DE DEA28444A patent/DE1116672B/de active Pending
-
1958
- 1958-04-15 US US728568A patent/US3018302A/en not_active Expired - Lifetime
- 1958-12-03 CH CH6689458A patent/CH370406A/de unknown
- 1958-12-03 GB GB39031/58A patent/GB853044A/en not_active Expired
-
1959
- 1959-07-27 US US829528A patent/US3074992A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| BE563332A (ja) | |
| CH370406A (de) | 1963-07-15 |
| GB853044A (en) | 1960-11-02 |
| FR75178E (ja) | 1961-09-08 |
| US3074992A (en) | 1963-01-22 |
| DE1116672B (de) | 1961-11-09 |
| CH361279A (de) | 1962-04-15 |
| DE1054997B (de) | 1959-04-16 |
| US3018302A (en) | 1962-01-23 |
| NL99649C (ja) | |
| GB812651A (en) | 1959-04-29 |
| FR1246708A (fr) | 1960-11-25 |
| BE554888A (ja) | |
| NL99688C (ja) | |
| DE1057119B (de) | 1959-05-14 |
| CH369451A (de) | 1963-05-31 |