BE563332A - - Google Patents

Info

Publication number
BE563332A
BE563332A BE563332DA BE563332A BE 563332 A BE563332 A BE 563332A BE 563332D A BE563332D A BE 563332DA BE 563332 A BE563332 A BE 563332A
Authority
BE
Belgium
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of BE563332A publication Critical patent/BE563332A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657154Cyclic esteramides of oxyacids of phosphorus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
BE563332D 1956-12-20 BE563332A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEA26234A DE1054997B (de) 1956-12-20 1956-12-20 Verfahren zur Herstellung von cyclischen Thiophosphorsaeure-esteramiden
DEA24298A DE1057119B (de) 1956-12-20 1957-12-04 Verfahren zur Herstellung von cyclischen Phosphorsaeure-esteramiden
DEA28444A DE1116672B (de) 1956-12-20 1957-12-04 Verfahren zur Herstellung von cyclischen Phosphorsaeure- und Thiophosphorsaeureesteramiden

Publications (1)

Publication Number Publication Date
BE563332A true BE563332A (ja)

Family

ID=27208860

Family Applications (2)

Application Number Title Priority Date Filing Date
BE563332D BE563332A (ja) 1956-12-20
BE554888D BE554888A (ja) 1956-12-20

Family Applications After (1)

Application Number Title Priority Date Filing Date
BE554888D BE554888A (ja) 1956-12-20

Country Status (7)

Country Link
US (2) US3018302A (ja)
BE (2) BE554888A (ja)
CH (3) CH361279A (ja)
DE (3) DE1054997B (ja)
FR (2) FR1246708A (ja)
GB (2) GB812651A (ja)
NL (3) NL99688C (ja)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3270093A (en) * 1963-04-19 1966-08-30 Tenneco Chem Omicron, omicron-neopentylene-nu-diethylphosphoroamidothioate
US3286001A (en) * 1963-06-07 1966-11-15 Continental Oil Co Reaction products of organophosphorus monohalides with mercaptoalkylamines
US3335129A (en) * 1963-11-21 1967-08-08 Wyandotte Chemicals Corp Phosphoramidates
DE2110333A1 (de) * 1971-03-04 1972-09-14 Audi Nsu Auto Union Ag Kreiskolben-Brennkraftmaschine
PL100390B1 (pl) 1975-10-06 1978-09-30 Sposob wytwarzania 2-tlenku-2-/bis/2-chloroetylo/-amino/-1-/okso-3-aza-2-fosfacykloheksanu/cyklofosfamidu/o czynnosci optycznej
DE3132221A1 (de) * 1981-08-14 1983-05-19 Behringwerke Ag, 3550 Marburg Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung
DE3133077A1 (de) * 1981-08-21 1983-03-10 Henkel KGaA, 4000 Düsseldorf Neue cytostatisch wirksame epoxidgruppen tragende 1,3,2-oxazaphosphorin-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung in pharmazeutischen zubereitungen
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide
US5227374A (en) * 1982-11-12 1993-07-13 Mead Johnson & Company Lyophilized cyclophosphamide
US4659699A (en) * 1983-08-22 1987-04-21 Cetus-Ben Venue Therapeutics Process for freeze drying cyclophosphamide
US4879286A (en) * 1987-01-28 1989-11-07 Lyphomed, Inc. Cyclophosphamide
IT1251472B (it) * 1991-09-12 1995-05-15 Boehringer Mannheim Italia Ossaazafosforine utili come agenti antitumorali, un processo per la loro preparazione e composizioni farmaceutiche che le contengono
DE19739159C1 (de) * 1997-09-06 1999-01-28 Asta Medica Ag Verfahren zur Herstellung von Oxazaphosphorin-2-aminen
US6312662B1 (en) 1998-03-06 2001-11-06 Metabasis Therapeutics, Inc. Prodrugs phosphorus-containing compounds
CA2322487C (en) 1998-03-06 2010-07-20 Metabasis Therapeutics, Inc. Novel prodrugs for phosphorus-containing compounds
US7205404B1 (en) * 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
DK1165570T3 (da) * 1999-03-05 2006-12-18 Metabasis Therapeutics Inc Nye phosphorholdige prodrugs
US6752981B1 (en) 1999-09-08 2004-06-22 Metabasis Therapeutics, Inc. Prodrugs for liver specific drug delivery
US7829084B2 (en) 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
WO2004037161A2 (en) * 2002-05-13 2004-05-06 Metabasis Therapeutics, Inc. Cyclic prodrugs of pmea one of its analogues
NZ536327A (en) 2002-05-13 2007-08-31 Metabasis Therapeutics Inc PMEA and PMPA cyclic producing synthesis
MXPA05004503A (es) * 2002-10-31 2005-08-16 Metabasis Therapeutics Inc Nuevos profarmacos de monofosfato de citarabina.
US20050182252A1 (en) * 2004-02-13 2005-08-18 Reddy K. R. Novel 2'-C-methyl nucleoside derivatives
RU2006138907A (ru) * 2004-06-08 2008-07-20 Метабазис Терапеутикс Синтез сложных циклических эфиров с применением кислоты льюиса
EP3105238A4 (en) 2014-02-13 2017-11-08 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
CN106456654A (zh) 2014-05-09 2017-02-22 奥罗医学制药有限公司 环磷酰胺液体浓缩制剂
EP3164136A4 (en) 2014-07-02 2018-04-04 Ligand Pharmaceuticals, Inc. Prodrug compounds and uses therof
WO2016005962A2 (en) 2014-07-11 2016-01-14 Dr. Reddy’S Laboratories Limited Stable liquid formulations of cyclophosphamide and processes
US10849916B2 (en) 2014-07-11 2020-12-01 Dr. Reddys Laboratories Limited Stable liquid formulations of cyclophosphamide and its impurities
EP3197438A4 (en) 2014-09-26 2018-06-20 Intas Pharmaceuticals Ltd. Pharmaceutical composition having improved content uniformity
AU2015371308A1 (en) 2014-12-23 2017-08-03 Intellectual Property Associates, Llc Methods and formulations for transdermal administration
EP3277700A1 (en) 2015-04-02 2018-02-07 Przedsi Biorstwo Produkcyjno-WDRO Eniowe Ifotam SP. Z.O.O Method of production of n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxazaphosphorine-2-amine 2-oxide
WO2017207719A1 (en) 2016-06-02 2017-12-07 Amneal Pharmaceuticals Company Gmbh Cyclophosphamide composition and method for preparation thereof
US20190083386A1 (en) 2017-09-15 2019-03-21 Ampersand Biopharmaceuticals, Inc. Methods and formulations for transdermal administration of buffering agents
US11970482B2 (en) 2018-01-09 2024-04-30 Ligand Pharmaceuticals Inc. Acetal compounds and therapeutic uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1065418B (de) * 1953-03-21 1959-09-17 Montecatini Soc. Gen. per 1'Industria Mineraria e Chimica, Mailand (Italien) Verfahren zur Herstellung von heterocyclischen Phosphorverbindungen
BE575869A (ja) * 1958-02-20 1900-01-01

Also Published As

Publication number Publication date
GB853044A (en) 1960-11-02
BE554888A (ja)
NL99649C (ja)
CH370406A (de) 1963-07-15
DE1057119B (de) 1959-05-14
US3018302A (en) 1962-01-23
US3074992A (en) 1963-01-22
DE1116672B (de) 1961-11-09
CH361279A (de) 1962-04-15
GB812651A (en) 1959-04-29
FR1246708A (fr) 1960-11-25
NL222157A (ja)
FR75178E (ja) 1961-09-08
CH369451A (de) 1963-05-31
NL99688C (ja)
DE1054997B (de) 1959-04-16

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