NL194665C - Zuurstofdragende meervoudige emulsie, werkwijze voor het bereiden daarvan, en bloedvervangingsmiddel dat een dergelijke emulsie bevat. - Google Patents

Zuurstofdragende meervoudige emulsie, werkwijze voor het bereiden daarvan, en bloedvervangingsmiddel dat een dergelijke emulsie bevat. Download PDF

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Publication number
NL194665C
NL194665C NL8902100A NL8902100A NL194665C NL 194665 C NL194665 C NL 194665C NL 8902100 A NL8902100 A NL 8902100A NL 8902100 A NL8902100 A NL 8902100A NL 194665 C NL194665 C NL 194665C
Authority
NL
Netherlands
Prior art keywords
emulsion
primary
volume percent
oxygen
multiple emulsion
Prior art date
Application number
NL8902100A
Other languages
English (en)
Dutch (nl)
Other versions
NL8902100A (nl
NL194665B (nl
Original Assignee
Northfield Lab
Illinois Technology Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northfield Lab, Illinois Technology Inst filed Critical Northfield Lab
Publication of NL8902100A publication Critical patent/NL8902100A/nl
Publication of NL194665B publication Critical patent/NL194665B/xx
Application granted granted Critical
Publication of NL194665C publication Critical patent/NL194665C/nl

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026Blood substitute; Oxygen transporting formulations; Plasma extender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113Multiple emulsions, e.g. oil-in-water-in-oil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/41Emulsifying
    • B01F23/4105Methods of emulsifying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/41Emulsifying
    • B01F23/414Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/922Colloid systems having specified particle size, range, or distribution, e.g. bimodal particle distribution
    • Y10S516/923Emulsion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NL8902100A 1988-08-19 1989-08-21 Zuurstofdragende meervoudige emulsie, werkwijze voor het bereiden daarvan, en bloedvervangingsmiddel dat een dergelijke emulsie bevat. NL194665C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/234,386 US5061688A (en) 1988-08-19 1988-08-19 Hemoglobin multiple emulsion
US23438688 1988-08-19

Publications (3)

Publication Number Publication Date
NL8902100A NL8902100A (nl) 1990-03-16
NL194665B NL194665B (nl) 2002-07-01
NL194665C true NL194665C (nl) 2002-11-04

Family

ID=22881174

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8902100A NL194665C (nl) 1988-08-19 1989-08-21 Zuurstofdragende meervoudige emulsie, werkwijze voor het bereiden daarvan, en bloedvervangingsmiddel dat een dergelijke emulsie bevat.

Country Status (12)

Country Link
US (3) US5061688A (es)
JP (1) JPH02160724A (es)
AU (1) AU614173B2 (es)
CA (1) CA1330937C (es)
CH (1) CH679206A5 (es)
DE (1) DE3927298C2 (es)
ES (1) ES2015777A6 (es)
FR (1) FR2635458B1 (es)
GB (1) GB2221912B (es)
IT (1) IT1232170B (es)
NL (1) NL194665C (es)
SE (1) SE504671C2 (es)

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US5256422A (en) * 1991-03-28 1993-10-26 Micro Vesicular Systems, Inc. Lipid vesicle containing water-in-oil emulsions
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US5670173A (en) * 1992-09-14 1997-09-23 Mcgill University Biodegradable polymer membrane containing hemoglobin for blood substitute
US6506340B1 (en) 1993-06-01 2003-01-14 Cobe Cardiovascular, Inc. Antifoaming device and method for extracorporeal blood processing
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US5725839A (en) * 1993-08-16 1998-03-10 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules for ERI or MRI
US5804561A (en) * 1993-08-16 1998-09-08 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5824781A (en) * 1993-08-16 1998-10-20 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5840701A (en) * 1993-08-16 1998-11-24 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5767089A (en) * 1993-08-16 1998-06-16 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5817632A (en) * 1993-08-16 1998-10-06 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
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US20030153491A1 (en) * 2002-01-11 2003-08-14 Winslow Robert M. Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
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Also Published As

Publication number Publication date
US5217648A (en) 1993-06-08
GB2221912B (en) 1992-09-23
GB2221912A (en) 1990-02-21
AU4008689A (en) 1990-02-22
JPH02160724A (ja) 1990-06-20
FR2635458B1 (fr) 1994-11-18
DE3927298A1 (de) 1990-03-01
SE8902773D0 (sv) 1989-08-18
GB8918880D0 (en) 1989-09-27
DE3927298C2 (de) 2003-02-06
AU614173B2 (en) 1991-08-22
CA1330937C (en) 1994-07-26
ES2015777A6 (es) 1990-09-01
SE8902773L (sv) 1990-02-20
CH679206A5 (es) 1992-01-15
FR2635458A1 (fr) 1990-02-23
US5061688A (en) 1991-10-29
NL8902100A (nl) 1990-03-16
SE504671C2 (sv) 1997-03-24
US5438041A (en) 1995-08-01
IT1232170B (it) 1992-01-25
NL194665B (nl) 2002-07-01
IT8948297A0 (it) 1989-08-21

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