NL194665B - Zuurstofdragende meervoudige emulsie, werkwijze voor het bereiden daarvan, en bloedvervangingsmiddel dat een dergelijke emulsie bevat. - Google Patents

Zuurstofdragende meervoudige emulsie, werkwijze voor het bereiden daarvan, en bloedvervangingsmiddel dat een dergelijke emulsie bevat.

Info

Publication number
NL194665B
NL194665B NL8902100A NL8902100A NL194665B NL 194665 B NL194665 B NL 194665B NL 8902100 A NL8902100 A NL 8902100A NL 8902100 A NL8902100 A NL 8902100A NL 194665 B NL194665 B NL 194665B
Authority
NL
Netherlands
Prior art keywords
emulsion
oxygen
preparing
blood substitute
bearing multiple
Prior art date
Application number
NL8902100A
Other languages
English (en)
Other versions
NL194665C (nl
NL8902100A (nl
Original Assignee
Illinois Technology Inst
Northfield Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illinois Technology Inst, Northfield Lab filed Critical Illinois Technology Inst
Publication of NL8902100A publication Critical patent/NL8902100A/nl
Publication of NL194665B publication Critical patent/NL194665B/nl
Application granted granted Critical
Publication of NL194665C publication Critical patent/NL194665C/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/4105—Methods of emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/922—Colloid systems having specified particle size, range, or distribution, e.g. bimodal particle distribution
    • Y10S516/923—Emulsion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NL8902100A 1988-08-19 1989-08-21 Zuurstofdragende meervoudige emulsie, werkwijze voor het bereiden daarvan, en bloedvervangingsmiddel dat een dergelijke emulsie bevat. NL194665C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23438688 1988-08-19
US07/234,386 US5061688A (en) 1988-08-19 1988-08-19 Hemoglobin multiple emulsion

Publications (3)

Publication Number Publication Date
NL8902100A NL8902100A (nl) 1990-03-16
NL194665B true NL194665B (nl) 2002-07-01
NL194665C NL194665C (nl) 2002-11-04

Family

ID=22881174

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8902100A NL194665C (nl) 1988-08-19 1989-08-21 Zuurstofdragende meervoudige emulsie, werkwijze voor het bereiden daarvan, en bloedvervangingsmiddel dat een dergelijke emulsie bevat.

Country Status (12)

Country Link
US (3) US5061688A (nl)
JP (1) JPH02160724A (nl)
AU (1) AU614173B2 (nl)
CA (1) CA1330937C (nl)
CH (1) CH679206A5 (nl)
DE (1) DE3927298C2 (nl)
ES (1) ES2015777A6 (nl)
FR (1) FR2635458B1 (nl)
GB (1) GB2221912B (nl)
IT (1) IT1232170B (nl)
NL (1) NL194665C (nl)
SE (1) SE504671C2 (nl)

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US5670173A (en) * 1992-09-14 1997-09-23 Mcgill University Biodegradable polymer membrane containing hemoglobin for blood substitute
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US5741893A (en) * 1993-08-16 1998-04-21 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5767089A (en) * 1993-08-16 1998-06-16 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5725839A (en) * 1993-08-16 1998-03-10 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules for ERI or MRI
US5824781A (en) * 1993-08-16 1998-10-20 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5840701A (en) * 1993-08-16 1998-11-24 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
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US20050164915A1 (en) * 2002-04-01 2005-07-28 Sangart, Inc. Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
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CN1733298B (zh) * 2005-08-16 2011-08-24 华东理工大学 血红蛋白为基础的微囊型血液代用品及其制备方法
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
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US8906855B2 (en) 2007-12-22 2014-12-09 Vivacelle Bio, Inc. Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
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US8618056B2 (en) 2007-12-22 2013-12-31 Cuthbert O. Simpkins Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
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US8273857B2 (en) * 2009-09-22 2012-09-25 Jen-Chang Hsia Compositions and methods of use of neurovascular protective multifunctional polynitroxylated pegylated carboxy hemoglobins for transfusion and critical care medicine
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Also Published As

Publication number Publication date
JPH02160724A (ja) 1990-06-20
AU614173B2 (en) 1991-08-22
FR2635458B1 (fr) 1994-11-18
US5061688A (en) 1991-10-29
US5217648A (en) 1993-06-08
SE504671C2 (sv) 1997-03-24
AU4008689A (en) 1990-02-22
CA1330937C (en) 1994-07-26
FR2635458A1 (fr) 1990-02-23
US5438041A (en) 1995-08-01
CH679206A5 (nl) 1992-01-15
ES2015777A6 (es) 1990-09-01
DE3927298C2 (de) 2003-02-06
DE3927298A1 (de) 1990-03-01
NL194665C (nl) 2002-11-04
GB2221912A (en) 1990-02-21
IT1232170B (it) 1992-01-25
NL8902100A (nl) 1990-03-16
SE8902773L (sv) 1990-02-20
GB8918880D0 (en) 1989-09-27
GB2221912B (en) 1992-09-23
IT8948297A0 (it) 1989-08-21
SE8902773D0 (sv) 1989-08-18

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Effective date: 20040301