ES2015777A6 - Emulsion multiple de hemoglobina. - Google Patents
Emulsion multiple de hemoglobina.Info
- Publication number
- ES2015777A6 ES2015777A6 ES8902899A ES8902899A ES2015777A6 ES 2015777 A6 ES2015777 A6 ES 2015777A6 ES 8902899 A ES8902899 A ES 8902899A ES 8902899 A ES8902899 A ES 8902899A ES 2015777 A6 ES2015777 A6 ES 2015777A6
- Authority
- ES
- Spain
- Prior art keywords
- oxygen
- oil
- hemoglobin
- multiple emulsion
- oxygen carrying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
- B01F23/4105—Methods of emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
- B01F23/414—Emulsifying characterised by the internal structure of the emulsion
- B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
- Y10S516/922—Colloid systems having specified particle size, range, or distribution, e.g. bimodal particle distribution
- Y10S516/923—Emulsion
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
EMULSION MULTIPLE DE HEMOGLOBINA. LA PRESENTE INVENCION PROPORCIONA UNA EMULSION MULTIPLE DE UN MATERIAL ACUOSO PORTADOR DE OXIGENO EN ACEITE EN UNA FASE ACUOSA EXTERNA, QUE ES ADECUADA PARA LA PROVISION DE OXIGENO EN PROCESOS DE TRANSFERENCIA DE OXIGENO. MAS CONCRETAMENTE, LA INVENCION PROPORCIONA UNA EMULSION MULTIPLE DE HEMOGLOBINA EN UN ACEITE FISIOLOGICAMENTE COMPATIBLE EN UNA SOLUCION SALINA ACUOSA EXTERNA, CUYAS GOTITAS TIENEN UN TAMAÑO SUFICIENTEMENTE PEQUEÑO PARA SUMINISTRAR UN FLUJO DE OXIGENO A TRAVES DE LOS VASOS SANGUINEOS A LOS TEJIDOS U ORGANOS CORPORALES DESEADOS, POR LO QUE CONSTITUYE UN SUSTITUTO DE SANGRE. LA INVENCION TAMBIEN PROPORCIONA UN PROCEDIMIENTO PARA FORMULAR LA HEMOGLOBINA, UN MATERIAL FRAGIL, EN EMULSIONES MULTIPLES DE AGUA EN ACEITE EN AGUA DE ALTO CONTENIDO EN HEMOGLOBINA, QUE MANTIENEN ALTOS RENDIMIENTOS Y TIENEN UNA BUENA ACTIVIDAD DE INTERCAMBIO DE OXIGENO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/234,386 US5061688A (en) | 1988-08-19 | 1988-08-19 | Hemoglobin multiple emulsion |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2015777A6 true ES2015777A6 (es) | 1990-09-01 |
Family
ID=22881174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8902899A Expired - Lifetime ES2015777A6 (es) | 1988-08-19 | 1989-08-18 | Emulsion multiple de hemoglobina. |
Country Status (12)
Country | Link |
---|---|
US (3) | US5061688A (es) |
JP (1) | JPH02160724A (es) |
AU (1) | AU614173B2 (es) |
CA (1) | CA1330937C (es) |
CH (1) | CH679206A5 (es) |
DE (1) | DE3927298C2 (es) |
ES (1) | ES2015777A6 (es) |
FR (1) | FR2635458B1 (es) |
GB (1) | GB2221912B (es) |
IT (1) | IT1232170B (es) |
NL (1) | NL194665C (es) |
SE (1) | SE504671C2 (es) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5061688A (en) * | 1988-08-19 | 1991-10-29 | Illinois Institute Of Technology | Hemoglobin multiple emulsion |
US5256422A (en) * | 1991-03-28 | 1993-10-26 | Micro Vesicular Systems, Inc. | Lipid vesicle containing water-in-oil emulsions |
US5622649A (en) * | 1991-06-27 | 1997-04-22 | Emory University | Multiple emulsions and methods of preparation |
EP0591452B1 (en) * | 1991-06-27 | 1998-05-06 | Emory University | Multiple emulsions and methods of preparation |
DE4136699A1 (de) * | 1991-11-07 | 1992-10-22 | Lancaster Group Ag | Verfahren zur herstellung von stabilen, komplexen emulsionssystemen des typs wasser-oel-wasser und deren verwendung als kosmetische praeparate |
US5670173A (en) * | 1992-09-14 | 1997-09-23 | Mcgill University | Biodegradable polymer membrane containing hemoglobin for blood substitute |
US6506340B1 (en) | 1993-06-01 | 2003-01-14 | Cobe Cardiovascular, Inc. | Antifoaming device and method for extracorporeal blood processing |
US5578564A (en) * | 1993-07-23 | 1996-11-26 | Somatogen, Inc. | Nickel-free hemoglobin and methods for producing such hemoglobin |
US5741893A (en) * | 1993-08-16 | 1998-04-21 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5725839A (en) * | 1993-08-16 | 1998-03-10 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules for ERI or MRI |
US5804561A (en) * | 1993-08-16 | 1998-09-08 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5824781A (en) * | 1993-08-16 | 1998-10-20 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5840701A (en) * | 1993-08-16 | 1998-11-24 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5767089A (en) * | 1993-08-16 | 1998-06-16 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5817632A (en) * | 1993-08-16 | 1998-10-06 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
US5807831A (en) * | 1993-08-16 | 1998-09-15 | Hsia; Jen-Chang | Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules |
TW381022B (en) * | 1993-08-16 | 2000-02-01 | Hsia Jen Chang | Compositions and methods utilizing nitroxides to avoid oxygen toxicity, particularly in stabilized, polymerized, conjugated, or encapsulated hemoglobin used as a red cell substitute |
DE4341113B4 (de) * | 1993-12-02 | 2006-04-13 | IFAC Institut für angewandte Colloidtechnologie GmbH & Co. KG | Stabile multiple X/O/Y-Emulsion |
DE4343833A1 (de) * | 1993-12-22 | 1995-06-29 | Beiersdorf Ag | W/O/W-Emulsionen |
US5589177A (en) * | 1994-12-06 | 1996-12-31 | Helene Curtis, Inc. | Rinse-off water-in-oil-in-water compositions |
US6436969B1 (en) * | 1995-09-12 | 2002-08-20 | Kansas University Medical Center Research Institute Inc. | Dialysis solutions and methods |
WO1997025978A1 (fr) * | 1996-01-15 | 1997-07-24 | BELOYARTSEV, Arkady Felixovich | Procede de production d'emulsions perfluorocarbonees a des fins medicales |
US5834519A (en) * | 1996-10-11 | 1998-11-10 | Wayne State University | Stabilized gas-supersaturated emulsions and suspensions |
US6054427A (en) * | 1997-02-28 | 2000-04-25 | The Regents Of The University Of California | Methods and compositions for optimization of oxygen transport by cell-free systems |
US5814601A (en) * | 1997-02-28 | 1998-09-29 | The Regents Of The University Of California | Methods and compositions for optimization of oxygen transport by cell-free systems |
WO1999043301A1 (en) * | 1998-02-24 | 1999-09-02 | The Board Of Trustees Of The University Of Illinois | Lipid emulsions in the treatment of systemic poisoning |
EP1038573B1 (en) * | 1999-03-19 | 2005-12-14 | Kao Corporation | Process for preparing emulsion |
US6500809B1 (en) | 1999-11-12 | 2002-12-31 | Neuron Therapeutics, Inc. | Hyperoncotic artificial cerebrospinal fluid and method of treating neural tissue edema therewith |
US6777450B1 (en) * | 2000-05-26 | 2004-08-17 | Color Access, Inc. | Water-thin emulsions with low emulsifier levels |
DE10034970B4 (de) * | 2000-07-19 | 2004-11-18 | Sanguibiotech Gmbh | Einen Sauerstoffträger, ausgewählt aus Hämoglobin oder Hämoglobin- und Myoglobin-enthaltende Zubereitung in Form einer Emulsion sowie deren Verwendung als kosmetisches Externum und zur natürlichen Regeneration der Haut bei Sauerstoff-Mangel |
US6747132B2 (en) | 2000-11-29 | 2004-06-08 | Apex Biosciences, Inc. | Methods for the synthesis of a modified hemoglobin solution |
WO2002076392A2 (en) * | 2001-03-21 | 2002-10-03 | Madash Llc | Thermally reversible water in oil in water emulsions |
KR20030097834A (ko) | 2001-04-18 | 2003-12-31 | 노쓰필드 라보라토리스, 인코포레이티드 | 안정화된 헤모글로빈 용액을 저장하기 위한 가요성 용기시스템 |
US20050164915A1 (en) | 2002-04-01 | 2005-07-28 | Sangart, Inc. | Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
US20030153491A1 (en) * | 2002-01-11 | 2003-08-14 | Winslow Robert M. | Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
DE10209860A1 (de) * | 2002-03-06 | 2003-09-25 | Hemofarm Konzern A D | Hydrophobe Nanotropfen mit gebundenen Hämoglobinmolekülen in hydrophiler Phase enthaltene Emulsion als Blutersatzstoff |
JP3912206B2 (ja) * | 2002-07-05 | 2007-05-09 | 株式会社日立製作所 | 筒内直接燃料噴射装置用燃料ポンプ |
US20040072729A1 (en) * | 2002-10-10 | 2004-04-15 | Sunbio Inc. | High oxygen affinity PEG-hemoglobin as treatment for brain stroke |
US9388427B2 (en) * | 2002-12-02 | 2016-07-12 | Biovec, Llc | In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors |
US7803365B2 (en) * | 2002-12-02 | 2010-09-28 | Biovec, Llc | Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases |
US7135553B2 (en) * | 2003-01-29 | 2006-11-14 | Northfield Laboratories, Inc. | Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing |
CA2515916A1 (en) * | 2003-02-25 | 2004-09-10 | Biovec B.V. | Therapeutic applications of thrombomodulin gene via viral and non-viral vectors |
US20050186183A1 (en) * | 2003-12-08 | 2005-08-25 | Deangelo Joseph | Stabilized products, processes and devices for preparing same |
US7087369B2 (en) * | 2003-12-17 | 2006-08-08 | The Regents Of The University Of California | Cornea preservation medium |
KR101327649B1 (ko) * | 2005-03-31 | 2013-11-12 | 산토리 홀딩스 가부시키가이샤 | 리그난류 화합물 함유 수중 유적형 에멀션 및 그것을함유하는 조성물 |
CN1733298B (zh) * | 2005-08-16 | 2011-08-24 | 华东理工大学 | 血红蛋白为基础的微囊型血液代用品及其制备方法 |
US20090004159A1 (en) * | 2006-01-24 | 2009-01-01 | The Board Of Trustees Of The University Of Illinoi | Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells |
EP1978802A2 (en) * | 2006-01-24 | 2008-10-15 | Northfield Laboratories, Inc. | Polymerized hemoglobin media and its use in isolation and transplantation of islet cells |
WO2008044550A1 (fr) * | 2006-10-04 | 2008-04-17 | Suntory Limited | Émulsion de type huile/eau/huile contenant un composé de lignane, et composition la contenant |
US8063020B2 (en) * | 2007-12-22 | 2011-11-22 | Simpkins Cuthbert O | Resuscitation fluid |
US8618056B2 (en) | 2007-12-22 | 2013-12-31 | Cuthbert O. Simpkins | Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries |
US8906855B2 (en) | 2007-12-22 | 2014-12-09 | Vivacelle Bio, Inc. | Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries |
KR20110042107A (ko) | 2008-08-07 | 2011-04-22 | 바이오엑티브 써지컬, 아이엔씨. | 의료 장치 및 이식물을 위한 줄기 세포 포획 및 고정화 코팅 |
CN102300555B (zh) * | 2009-01-30 | 2015-06-17 | 卡斯伯特·O·辛普金斯 | 复苏液 |
WO2010125558A1 (en) * | 2009-04-28 | 2010-11-04 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), The Volcani Center | Emulsions, emulsifier, method of use and production process |
US8273857B2 (en) * | 2009-09-22 | 2012-09-25 | Jen-Chang Hsia | Compositions and methods of use of neurovascular protective multifunctional polynitroxylated pegylated carboxy hemoglobins for transfusion and critical care medicine |
DE102011118500A1 (de) * | 2011-11-15 | 2013-05-16 | Planaturo GmbH & Co. KG | Vegane Emulsion |
US11119098B2 (en) | 2014-10-31 | 2021-09-14 | Massachusetts Institute Of Technology | Systems including Janus droplets |
US10252231B2 (en) | 2014-10-31 | 2019-04-09 | Massachusetts Institute Of Technology | Compositions and methods for forming emulsions |
ES2721306T3 (es) | 2014-12-02 | 2019-07-30 | Novartis Ag | Fabricación de composiciones que contienen tensioactivo |
CA3046802A1 (en) | 2017-01-08 | 2018-07-12 | Resq Pharma, Inc. | Methods for decreasing injuries associated with intraoperative hypotension |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3823091A (en) * | 1971-05-19 | 1974-07-09 | Green Cross Corp | Stable emulsion of fluorocarbon particles |
US3823901A (en) * | 1973-07-24 | 1974-07-16 | Us Navy | Aerial launch system |
US3993581A (en) * | 1973-10-05 | 1976-11-23 | The Green Cross Corporation | Process for preparing stable oxygen transferable emulsion |
US4146499A (en) * | 1976-09-18 | 1979-03-27 | Rosano Henri L | Method for preparing microemulsions |
US4390521A (en) * | 1980-04-11 | 1983-06-28 | Exxon Research And Engineering Co. | Artificial red cells |
US4376059A (en) * | 1980-04-11 | 1983-03-08 | Exxon Research And Engineering Co. | Process for preparing artificial red cells |
US4569784A (en) * | 1980-11-17 | 1986-02-11 | Adamantech, Inc. | Preparation of a gel having gas transporting capability |
US4533254A (en) * | 1981-04-17 | 1985-08-06 | Biotechnology Development Corporation | Apparatus for forming emulsions |
US4461717A (en) * | 1982-03-19 | 1984-07-24 | Sun Tech, Inc. | Stable gas-carrying compositions |
US4612370A (en) * | 1982-04-02 | 1986-09-16 | The Regents Of The University Of California | Lipid-saccharide reaction products |
US4425334A (en) * | 1982-04-02 | 1984-01-10 | The Regents Of The University Of California | Functional oxygen transport system |
EP0120967B1 (en) * | 1982-10-01 | 1987-06-03 | Meiji Milk Products Company Limited | Process for producing w/o/w oil-and-fat composition for food use |
JPS60183031A (ja) * | 1984-03-02 | 1985-09-18 | Meiji Milk Prod Co Ltd | W/o/w型複合エマルジヨンの製造法 |
FR2589160B1 (fr) * | 1985-10-29 | 1988-01-08 | Elf France | Composition d'hydrocarbures lourds a viscosite abaissee sous forme d'emulsion multiple, et procede pour sa preparation |
US4865836A (en) * | 1986-01-14 | 1989-09-12 | Fluoromed Pharmaceutical, Inc. | Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport |
US4808334A (en) * | 1986-07-11 | 1989-02-28 | Fuji Oil Company, Ltd. | Production of sterile composite emulsion |
US4776991A (en) * | 1986-08-29 | 1988-10-11 | The United States Of America As Represented By The Secretary Of The Navy | Scaled-up production of liposome-encapsulated hemoglobin |
AU2807689A (en) * | 1986-09-19 | 1989-03-01 | Chemex Pharmaceuticals Inc. | Method for the treatment of body tissues and the administration of drugs thereto |
US4866096A (en) * | 1987-03-20 | 1989-09-12 | Air Products And Chemicals, Inc. | Stable fluorochemical aqueous emulsions |
US5061688A (en) * | 1988-08-19 | 1991-10-29 | Illinois Institute Of Technology | Hemoglobin multiple emulsion |
-
1988
- 1988-08-19 US US07/234,386 patent/US5061688A/en not_active Expired - Fee Related
-
1989
- 1989-08-18 CA CA000608778A patent/CA1330937C/en not_active Expired - Fee Related
- 1989-08-18 ES ES8902899A patent/ES2015777A6/es not_active Expired - Lifetime
- 1989-08-18 GB GB8918880A patent/GB2221912B/en not_active Expired - Lifetime
- 1989-08-18 SE SE8902773A patent/SE504671C2/sv not_active IP Right Cessation
- 1989-08-18 DE DE3927298A patent/DE3927298C2/de not_active Expired - Fee Related
- 1989-08-18 CH CH3035/89A patent/CH679206A5/de not_active IP Right Cessation
- 1989-08-19 JP JP1214018A patent/JPH02160724A/ja active Pending
- 1989-08-21 IT IT8948297A patent/IT1232170B/it active
- 1989-08-21 AU AU40086/89A patent/AU614173B2/en not_active Ceased
- 1989-08-21 NL NL8902100A patent/NL194665C/nl not_active IP Right Cessation
- 1989-08-21 FR FR898911078A patent/FR2635458B1/fr not_active Expired - Fee Related
-
1991
- 1991-10-11 US US07/776,062 patent/US5217648A/en not_active Expired - Fee Related
-
1993
- 1993-03-03 US US08/025,608 patent/US5438041A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5217648A (en) | 1993-06-08 |
GB2221912B (en) | 1992-09-23 |
NL194665C (nl) | 2002-11-04 |
GB2221912A (en) | 1990-02-21 |
AU4008689A (en) | 1990-02-22 |
JPH02160724A (ja) | 1990-06-20 |
FR2635458B1 (fr) | 1994-11-18 |
DE3927298A1 (de) | 1990-03-01 |
SE8902773D0 (sv) | 1989-08-18 |
GB8918880D0 (en) | 1989-09-27 |
DE3927298C2 (de) | 2003-02-06 |
AU614173B2 (en) | 1991-08-22 |
CA1330937C (en) | 1994-07-26 |
SE8902773L (sv) | 1990-02-20 |
CH679206A5 (es) | 1992-01-15 |
FR2635458A1 (fr) | 1990-02-23 |
US5061688A (en) | 1991-10-29 |
NL8902100A (nl) | 1990-03-16 |
SE504671C2 (sv) | 1997-03-24 |
US5438041A (en) | 1995-08-01 |
IT1232170B (it) | 1992-01-25 |
NL194665B (nl) | 2002-07-01 |
IT8948297A0 (it) | 1989-08-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2015777A6 (es) | Emulsion multiple de hemoglobina. | |
Cameron et al. | Aerial gas exchange in the coconut crab, Birgus latro with some notes on Gecarcoidea lalandii | |
AU584724B2 (en) | Oxygenated fluorocarbon for use intra peritoneal perfusions | |
CA2297082A1 (en) | Therapeutic and dietary compositions containing essential fatty acids and bioactive disulphides | |
EP0510185B1 (en) | Blood platelet storage medium | |
DE3380788D1 (en) | Microencapsulation of living tissue and cells | |
HU910979D0 (en) | Process for the prodiction of medical preparations with n-neuropeptide-antagonistic effect, containing guanidine derivatives | |
AU1141288A (en) | Production of proteins in active forms | |
RU2000100923A (ru) | Уменьшение нежелательных побочных эффектов при использовании адсорбирующих изделий с помощью регулирования уровня ph | |
IE842618L (en) | Sotrage of red blood cells | |
SE9600631D0 (sv) | Use of a solution comprising glucose for peritonial dialysis having reduced formation of AGE products | |
US4911925A (en) | Vegetable extracts for skin treatment | |
US5218958A (en) | Placental chamber - artificial uterus | |
EP0224453A3 (en) | Biologically active topical collagen support matrix: cosmetic and pharmaceutical uses and a process for its preparation | |
DE69015910D1 (de) | Pharmazeutische Verwendung von Fettsäuren. | |
EP0150574A3 (en) | Treating marine alga to provide desalinating activity | |
SE8800545L (sv) | Alster och foerfarande foer processkontroll | |
JPS6239520A (ja) | アスコルビン酸カルシウムの投与装置 | |
SU1839983A1 (ru) | Способ лечения декомпрессионной болезни | |
Lâuar et al. | Release of tissue kallikrein from the isolated perfused kidney | |
Salmon et al. | Perfusion of the isolated canine stomach: A preliminary report | |
de Takats | ACUTE ARTERIAL INJURIES | |
KR970073367A (ko) | 어류 양식용 사료 | |
NUTRITION | requisite of the surgical operation of the present day. | |
Jones | Hyperbaric Technicians and Nurses Association Inc Conference Report-Fremantle, WA, 2-4 September 1994 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
SA6 | Expiration date (snapshot 920101) |
Free format text: 2009-08-18 |