FR2635458B1 - Emulsion multiple de transport d'oxygene utile notamment comme succedane du sang et son procede de fabrication - Google Patents

Emulsion multiple de transport d'oxygene utile notamment comme succedane du sang et son procede de fabrication

Info

Publication number
FR2635458B1
FR2635458B1 FR898911078A FR8911078A FR2635458B1 FR 2635458 B1 FR2635458 B1 FR 2635458B1 FR 898911078 A FR898911078 A FR 898911078A FR 8911078 A FR8911078 A FR 8911078A FR 2635458 B1 FR2635458 B1 FR 2635458B1
Authority
FR
France
Prior art keywords
manufacturing
multiple emulsion
blood substitute
transporting oxygen
oxygen useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR898911078A
Other languages
English (en)
Other versions
FR2635458A1 (fr
Inventor
Richard L Beissinger
Darsh T Wasan
Lakshman R Sehgal
Arthur L Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ILLINOIS INSTITUTE TECHNOLOGY
NORTHFIELD LAB
Northfield Laboratories Inc
Illinois Institute of Technology
Original Assignee
ILLINOIS INSTITUTE TECHNOLOGY
NORTHFIELD LAB
Northfield Laboratories Inc
Illinois Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ILLINOIS INSTITUTE TECHNOLOGY, NORTHFIELD LAB, Northfield Laboratories Inc, Illinois Institute of Technology filed Critical ILLINOIS INSTITUTE TECHNOLOGY
Publication of FR2635458A1 publication Critical patent/FR2635458A1/fr
Application granted granted Critical
Publication of FR2635458B1 publication Critical patent/FR2635458B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/4105—Methods of emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/922—Colloid systems having specified particle size, range, or distribution, e.g. bimodal particle distribution
    • Y10S516/923—Emulsion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR898911078A 1988-08-19 1989-08-21 Emulsion multiple de transport d'oxygene utile notamment comme succedane du sang et son procede de fabrication Expired - Fee Related FR2635458B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/234,386 US5061688A (en) 1988-08-19 1988-08-19 Hemoglobin multiple emulsion

Publications (2)

Publication Number Publication Date
FR2635458A1 FR2635458A1 (fr) 1990-02-23
FR2635458B1 true FR2635458B1 (fr) 1994-11-18

Family

ID=22881174

Family Applications (1)

Application Number Title Priority Date Filing Date
FR898911078A Expired - Fee Related FR2635458B1 (fr) 1988-08-19 1989-08-21 Emulsion multiple de transport d'oxygene utile notamment comme succedane du sang et son procede de fabrication

Country Status (12)

Country Link
US (3) US5061688A (fr)
JP (1) JPH02160724A (fr)
AU (1) AU614173B2 (fr)
CA (1) CA1330937C (fr)
CH (1) CH679206A5 (fr)
DE (1) DE3927298C2 (fr)
ES (1) ES2015777A6 (fr)
FR (1) FR2635458B1 (fr)
GB (1) GB2221912B (fr)
IT (1) IT1232170B (fr)
NL (1) NL194665C (fr)
SE (1) SE504671C2 (fr)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5061688A (en) * 1988-08-19 1991-10-29 Illinois Institute Of Technology Hemoglobin multiple emulsion
US5256422A (en) * 1991-03-28 1993-10-26 Micro Vesicular Systems, Inc. Lipid vesicle containing water-in-oil emulsions
US5622649A (en) * 1991-06-27 1997-04-22 Emory University Multiple emulsions and methods of preparation
EP0591452B1 (fr) * 1991-06-27 1998-05-06 Emory University Emulsions a plusieurs composants et leurs procedes de preparation
DE4136699A1 (de) * 1991-11-07 1992-10-22 Lancaster Group Ag Verfahren zur herstellung von stabilen, komplexen emulsionssystemen des typs wasser-oel-wasser und deren verwendung als kosmetische praeparate
US5670173A (en) * 1992-09-14 1997-09-23 Mcgill University Biodegradable polymer membrane containing hemoglobin for blood substitute
US6506340B1 (en) 1993-06-01 2003-01-14 Cobe Cardiovascular, Inc. Antifoaming device and method for extracorporeal blood processing
US5578564A (en) * 1993-07-23 1996-11-26 Somatogen, Inc. Nickel-free hemoglobin and methods for producing such hemoglobin
US5741893A (en) * 1993-08-16 1998-04-21 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5725839A (en) * 1993-08-16 1998-03-10 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules for ERI or MRI
US5804561A (en) * 1993-08-16 1998-09-08 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5824781A (en) * 1993-08-16 1998-10-20 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5840701A (en) * 1993-08-16 1998-11-24 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5767089A (en) * 1993-08-16 1998-06-16 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5817632A (en) * 1993-08-16 1998-10-06 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
US5807831A (en) * 1993-08-16 1998-09-15 Hsia; Jen-Chang Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules
TW381022B (en) * 1993-08-16 2000-02-01 Hsia Jen Chang Compositions and methods utilizing nitroxides to avoid oxygen toxicity, particularly in stabilized, polymerized, conjugated, or encapsulated hemoglobin used as a red cell substitute
DE4341113B4 (de) * 1993-12-02 2006-04-13 IFAC Institut für angewandte Colloidtechnologie GmbH & Co. KG Stabile multiple X/O/Y-Emulsion
DE4343833A1 (de) * 1993-12-22 1995-06-29 Beiersdorf Ag W/O/W-Emulsionen
US5589177A (en) * 1994-12-06 1996-12-31 Helene Curtis, Inc. Rinse-off water-in-oil-in-water compositions
US6436969B1 (en) * 1995-09-12 2002-08-20 Kansas University Medical Center Research Institute Inc. Dialysis solutions and methods
WO1997025978A1 (fr) * 1996-01-15 1997-07-24 BELOYARTSEV, Arkady Felixovich Procede de production d'emulsions perfluorocarbonees a des fins medicales
US5834519A (en) * 1996-10-11 1998-11-10 Wayne State University Stabilized gas-supersaturated emulsions and suspensions
US6054427A (en) * 1997-02-28 2000-04-25 The Regents Of The University Of California Methods and compositions for optimization of oxygen transport by cell-free systems
US5814601A (en) * 1997-02-28 1998-09-29 The Regents Of The University Of California Methods and compositions for optimization of oxygen transport by cell-free systems
WO1999043301A1 (fr) * 1998-02-24 1999-09-02 The Board Of Trustees Of The University Of Illinois Emulsions lipides pour le traitement de l'intoxication generale
EP1038573B1 (fr) * 1999-03-19 2005-12-14 Kao Corporation Procédé pour préparer une émulsion
US6500809B1 (en) 1999-11-12 2002-12-31 Neuron Therapeutics, Inc. Hyperoncotic artificial cerebrospinal fluid and method of treating neural tissue edema therewith
US6777450B1 (en) * 2000-05-26 2004-08-17 Color Access, Inc. Water-thin emulsions with low emulsifier levels
DE10034970B4 (de) * 2000-07-19 2004-11-18 Sanguibiotech Gmbh Einen Sauerstoffträger, ausgewählt aus Hämoglobin oder Hämoglobin- und Myoglobin-enthaltende Zubereitung in Form einer Emulsion sowie deren Verwendung als kosmetisches Externum und zur natürlichen Regeneration der Haut bei Sauerstoff-Mangel
US6747132B2 (en) 2000-11-29 2004-06-08 Apex Biosciences, Inc. Methods for the synthesis of a modified hemoglobin solution
WO2002076392A2 (fr) * 2001-03-21 2002-10-03 Madash Llc Emulsions eau dans huile dans eau thermiquement reversibles
KR20030097834A (ko) 2001-04-18 2003-12-31 노쓰필드 라보라토리스, 인코포레이티드 안정화된 헤모글로빈 용액을 저장하기 위한 가요성 용기시스템
US20050164915A1 (en) 2002-04-01 2005-07-28 Sangart, Inc. Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
US20030153491A1 (en) * 2002-01-11 2003-08-14 Winslow Robert M. Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
DE10209860A1 (de) * 2002-03-06 2003-09-25 Hemofarm Konzern A D Hydrophobe Nanotropfen mit gebundenen Hämoglobinmolekülen in hydrophiler Phase enthaltene Emulsion als Blutersatzstoff
JP3912206B2 (ja) * 2002-07-05 2007-05-09 株式会社日立製作所 筒内直接燃料噴射装置用燃料ポンプ
US20040072729A1 (en) * 2002-10-10 2004-04-15 Sunbio Inc. High oxygen affinity PEG-hemoglobin as treatment for brain stroke
US9388427B2 (en) * 2002-12-02 2016-07-12 Biovec, Llc In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors
US7803365B2 (en) * 2002-12-02 2010-09-28 Biovec, Llc Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases
US7135553B2 (en) * 2003-01-29 2006-11-14 Northfield Laboratories, Inc. Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing
CA2515916A1 (fr) * 2003-02-25 2004-09-10 Biovec B.V. Applications therapeutiques du gene de la thrombomoduline au moyen de vecteurs viraux et non viraux
US20050186183A1 (en) * 2003-12-08 2005-08-25 Deangelo Joseph Stabilized products, processes and devices for preparing same
US7087369B2 (en) * 2003-12-17 2006-08-08 The Regents Of The University Of California Cornea preservation medium
KR101327649B1 (ko) * 2005-03-31 2013-11-12 산토리 홀딩스 가부시키가이샤 리그난류 화합물 함유 수중 유적형 에멀션 및 그것을함유하는 조성물
CN1733298B (zh) * 2005-08-16 2011-08-24 华东理工大学 血红蛋白为基础的微囊型血液代用品及其制备方法
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
EP1978802A2 (fr) * 2006-01-24 2008-10-15 Northfield Laboratories, Inc. Milieu d´hemoglobine polymerisee et son utilisation pour l´isolation et la transplantation d´ilots de langerhans
WO2008044550A1 (fr) * 2006-10-04 2008-04-17 Suntory Limited Émulsion de type huile/eau/huile contenant un composé de lignane, et composition la contenant
US8063020B2 (en) * 2007-12-22 2011-11-22 Simpkins Cuthbert O Resuscitation fluid
US8618056B2 (en) 2007-12-22 2013-12-31 Cuthbert O. Simpkins Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
US8906855B2 (en) 2007-12-22 2014-12-09 Vivacelle Bio, Inc. Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
KR20110042107A (ko) 2008-08-07 2011-04-22 바이오엑티브 써지컬, 아이엔씨. 의료 장치 및 이식물을 위한 줄기 세포 포획 및 고정화 코팅
CN102300555B (zh) * 2009-01-30 2015-06-17 卡斯伯特·O·辛普金斯 复苏液
WO2010125558A1 (fr) * 2009-04-28 2010-11-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), The Volcani Center Émulsions, émulseur, procédé d'utilisation et procédé de production correspondants
US8273857B2 (en) * 2009-09-22 2012-09-25 Jen-Chang Hsia Compositions and methods of use of neurovascular protective multifunctional polynitroxylated pegylated carboxy hemoglobins for transfusion and critical care medicine
DE102011118500A1 (de) * 2011-11-15 2013-05-16 Planaturo GmbH & Co. KG Vegane Emulsion
US11119098B2 (en) 2014-10-31 2021-09-14 Massachusetts Institute Of Technology Systems including Janus droplets
US10252231B2 (en) 2014-10-31 2019-04-09 Massachusetts Institute Of Technology Compositions and methods for forming emulsions
ES2721306T3 (es) 2014-12-02 2019-07-30 Novartis Ag Fabricación de composiciones que contienen tensioactivo
CA3046802A1 (fr) 2017-01-08 2018-07-12 Resq Pharma, Inc. Procedes de reduction des lesions associees a l'hypotension peroperatoire

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3823091A (en) * 1971-05-19 1974-07-09 Green Cross Corp Stable emulsion of fluorocarbon particles
US3823901A (en) * 1973-07-24 1974-07-16 Us Navy Aerial launch system
US3993581A (en) * 1973-10-05 1976-11-23 The Green Cross Corporation Process for preparing stable oxygen transferable emulsion
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
US4390521A (en) * 1980-04-11 1983-06-28 Exxon Research And Engineering Co. Artificial red cells
US4376059A (en) * 1980-04-11 1983-03-08 Exxon Research And Engineering Co. Process for preparing artificial red cells
US4569784A (en) * 1980-11-17 1986-02-11 Adamantech, Inc. Preparation of a gel having gas transporting capability
US4533254A (en) * 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
US4461717A (en) * 1982-03-19 1984-07-24 Sun Tech, Inc. Stable gas-carrying compositions
US4612370A (en) * 1982-04-02 1986-09-16 The Regents Of The University Of California Lipid-saccharide reaction products
US4425334A (en) * 1982-04-02 1984-01-10 The Regents Of The University Of California Functional oxygen transport system
EP0120967B1 (fr) * 1982-10-01 1987-06-03 Meiji Milk Products Company Limited Procede de production de compositions alimentaires d'huile et de graisse a emulsion eau/huile/eau
JPS60183031A (ja) * 1984-03-02 1985-09-18 Meiji Milk Prod Co Ltd Ｗ／ｏ／ｗ型複合エマルジヨンの製造法
FR2589160B1 (fr) * 1985-10-29 1988-01-08 Elf France Composition d'hydrocarbures lourds a viscosite abaissee sous forme d'emulsion multiple, et procede pour sa preparation
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4808334A (en) * 1986-07-11 1989-02-28 Fuji Oil Company, Ltd. Production of sterile composite emulsion
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
AU2807689A (en) * 1986-09-19 1989-03-01 Chemex Pharmaceuticals Inc. Method for the treatment of body tissues and the administration of drugs thereto
US4866096A (en) * 1987-03-20 1989-09-12 Air Products And Chemicals, Inc. Stable fluorochemical aqueous emulsions
US5061688A (en) * 1988-08-19 1991-10-29 Illinois Institute Of Technology Hemoglobin multiple emulsion

Also Published As

Publication number Publication date
US5217648A (en) 1993-06-08
GB2221912B (en) 1992-09-23
NL194665C (nl) 2002-11-04
GB2221912A (en) 1990-02-21
AU4008689A (en) 1990-02-22
JPH02160724A (ja) 1990-06-20
DE3927298A1 (de) 1990-03-01
SE8902773D0 (sv) 1989-08-18
GB8918880D0 (en) 1989-09-27
DE3927298C2 (de) 2003-02-06
AU614173B2 (en) 1991-08-22
CA1330937C (fr) 1994-07-26
ES2015777A6 (es) 1990-09-01
SE8902773L (sv) 1990-02-20
CH679206A5 (fr) 1992-01-15
FR2635458A1 (fr) 1990-02-23
US5061688A (en) 1991-10-29
NL8902100A (nl) 1990-03-16
SE504671C2 (sv) 1997-03-24
US5438041A (en) 1995-08-01
IT1232170B (it) 1992-01-25
NL194665B (nl) 2002-07-01
IT8948297A0 (it) 1989-08-21

Similar Documents

Publication Publication Date Title
FR2635458B1 (fr) Emulsion multiple de transport d'oxygene utile notamment comme succedane du sang et son procede de fabrication
DE69422997T2 (de) Blutsauerstoffsystem und herstellverfahren
DE3887478D1 (de) Methode zur Herstellung eines Oxid-Supraleiters.
FI103980B (fi) Biaksiaalisesti venytetty polypropeeniyksikerroskalvo, menetelmä sen valmistamiseksi ja sen käyttö
FR2704418B1 (fr) Tube contenant un activateur de la coagulation du sang et son procede de preparation.
ITTO910817A1 (it) "articoli riflettenti e metodo per la loro fabbricazione".
DE69431023D1 (de) Halbleiteraufbau und Verfahren zur Herstellung
DE69216615D1 (de) Entwässerte Blutzellen und Verfahren zur Herstellung
DE3689503D1 (de) Multifilament-Supraleiterdrähte und Verfahren zu deren Herstellung.
ITRM910579A0 (it) Metodo per trasportare rocche di filo
DE68928155D1 (de) Oxidischer Supraleiter und Methode zu dessen Herstellung
DE69627489D1 (de) MULTIFilament-GEGENSTÄNDE AUS BSCCO 2223-OXID SUPRALEITERN UND VERFAHREN ZU IHRER HERSTELLUNG
DE69215016D1 (de) Josephson-Kontakte in Hochtemperatur Supraleitern und Verfahren zu deren Herstellung
DE69106742D1 (de) Verfahren uund Vorrichtung zur Herstellung von dünnen Schichten aus supraleitendem Oxyd.
DE69029234D1 (de) Verfahren zur Herstellung von Dünnschichtsupraleitern und supraleitenden Einrichtungen
DE59408569D1 (de) Multifilament-Garn aus Polyäthylennaphthalat und Verfahren zu seiner Herstellung
DE68927945D1 (de) Supraleitendes gesintertes Teil aus Oxiden und Verfahren zu seiner Herstellung
FI962549A0 (fi) Metallinen siirrännäinen ja menetelmä metallisen siirrännäisen käsittelemiseksi
DE69227274T2 (de) Supraleitender Gegenstand und Verfahren zur Herstellung diesen supraleitenden Gegenstand
DE3854493D1 (de) Verfahren zur Herstellung eines Dünnschichtsupraleiters.
DE69012422D1 (de) Methode zur Herstellung eines Oxydsupraleiterfilms.
DE69408285D1 (de) Verfahren zur Herstellung von supraleitenden Josephson Hochtemperaturanordnungen
DE69011582D1 (de) Methode zur Herstellung supraleitender Artikel.
ATE136299T1 (de) Verfahren zur herstellung der racemischen und optisch aktiven 1,2,3,4-tetrahydroisochinolin-3- carbonsäure sowie deren vorprodukte
FR2744393B1 (fr) Film d'enregistrement et son procede de fabrication

Legal Events

Date Code Title Description
ST Notification of lapse