NL194300C - Farmaceutisch preparaat, dat een polyprenol als werkzaam bestanddeel bevat, alsmede voor toepassing daarin geschikte polyprenolen. - Google Patents

Farmaceutisch preparaat, dat een polyprenol als werkzaam bestanddeel bevat, alsmede voor toepassing daarin geschikte polyprenolen. Download PDF

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Publication number
NL194300C
NL194300C NL8301892A NL8301892A NL194300C NL 194300 C NL194300 C NL 194300C NL 8301892 A NL8301892 A NL 8301892A NL 8301892 A NL8301892 A NL 8301892A NL 194300 C NL194300 C NL 194300C
Authority
NL
Netherlands
Prior art keywords
compound
polyprenols
polyprenol
formula
preparation
Prior art date
Application number
NL8301892A
Other languages
English (en)
Dutch (nl)
Other versions
NL8301892A (nl
NL194300B (nl
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57089806A external-priority patent/JPS58206517A/ja
Priority claimed from JP10620382A external-priority patent/JPS58225014A/ja
Priority claimed from JP18364382A external-priority patent/JPS5973533A/ja
Priority claimed from JP18364282A external-priority patent/JPS5973513A/ja
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of NL8301892A publication Critical patent/NL8301892A/nl
Priority to NL9900009A priority Critical patent/NL9900009A/nl
Publication of NL194300B publication Critical patent/NL194300B/xx
Application granted granted Critical
Publication of NL194300C publication Critical patent/NL194300C/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/15—Unsaturated ethers containing only non-aromatic carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/203—Unsaturated compounds containing keto groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/14—Acetic acid esters of monohydroxylic compounds
    • C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12C—BEER; PREPARATION OF BEER BY FERMENTATION; PREPARATION OF MALT FOR MAKING BEER; PREPARATION OF HOPS FOR MAKING BEER
    • C12C11/00—Fermentation processes for beer
    • C12C11/02—Pitching yeast

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8301892A 1982-05-28 1983-05-27 Farmaceutisch preparaat, dat een polyprenol als werkzaam bestanddeel bevat, alsmede voor toepassing daarin geschikte polyprenolen. NL194300C (nl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL9900009A NL9900009A (nl) 1982-05-28 2000-12-05 Beta, gamma-dihydropolyprenylalcoholderivaten en farmaceutisch preparaat, dat een polyprenylverbinding bevat.

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP8980682 1982-05-28
JP57089806A JPS58206517A (ja) 1982-05-28 1982-05-28 免疫機能不全による疾患の予防・治療剤
JP10620382A JPS58225014A (ja) 1982-06-22 1982-06-22 免疫機能不全による疾患の予防・治療剤
JP10620382 1982-06-22
JP18364282 1982-10-21
JP18364382 1982-10-21
JP18364382A JPS5973533A (ja) 1982-10-21 1982-10-21 β，γ−ジヒドロポリプレニルアルコ−ル誘導体
JP18364282A JPS5973513A (ja) 1982-10-21 1982-10-21 免疫機能不全による疾患の予防・治療剤

Publications (3)

Publication Number Publication Date
NL8301892A NL8301892A (nl) 1983-12-16
NL194300B NL194300B (nl) 2001-08-01
NL194300C true NL194300C (nl) 2001-12-04

Family

ID=27467677

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8301892A NL194300C (nl) 1982-05-28 1983-05-27 Farmaceutisch preparaat, dat een polyprenol als werkzaam bestanddeel bevat, alsmede voor toepassing daarin geschikte polyprenolen.

Country Status (12)

Country Link
US (3) US4624966A (sv)
AT (1) AT389871B (sv)
CA (1) CA1310660C (sv)
CH (1) CH654823A5 (sv)
DE (2) DE3318989C2 (sv)
DK (1) DK171640B1 (sv)
ES (3) ES8406992A1 (sv)
FR (5) FR2527597B1 (sv)
GB (7) GB2122610B (sv)
IT (1) IT1164256B (sv)
NL (1) NL194300C (sv)
SE (4) SE461650B (sv)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318989C2 (de) * 1982-05-28 1996-11-21 Eisai Co Ltd ß,gamma-Dihydropolyprenylalkoholderivate und diese enthaltende Arzneimittel und deren Verwendung
JPS6112622A (ja) * 1984-06-29 1986-01-21 Kuraray Co Ltd 造血幹細胞の分化増殖促進剤
JPH0759504B2 (ja) * 1986-01-23 1995-06-28 エーザイ株式会社 ポリプレニルアルコ−ル含有注射剤
US5071879A (en) * 1989-04-28 1991-12-10 Lidak Pharmaceuticals Systemic antiviral treatment
US5070107A (en) * 1989-04-28 1991-12-03 Lidak Pharmaceuticals Systemic antiviral treatment
JP3166991B2 (ja) * 1992-08-17 2001-05-14 日清製粉株式会社 （ｓ）−２，３−ジヒドロポリプレノール化合物を有効成分とする癌増殖抑制および／または癌転移抑制剤
US5602184A (en) * 1993-03-03 1997-02-11 The United States Of America As Represented By Department Of Health And Human Services Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
SG43833A1 (en) * 1993-12-13 1997-11-14 Lidak Pharmaceuticals Sucrose ester-c20 to c25 alcohol formulations
TW338042B (en) * 1995-10-31 1998-08-11 Clary Kk Process for producing all trans-form polyprenols
GB2310138A (en) * 1996-02-19 1997-08-20 Juris Rubens Immunomodulating plant polyprenols
US6440980B1 (en) 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
US5952392A (en) * 1996-09-17 1999-09-14 Avanir Pharmaceuticals Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition
PL334066A1 (en) * 1996-12-12 2000-01-31 Upjohn Co Oily composition of dihydropolyprenoles
CA2234326C (en) * 1997-04-25 2001-07-31 Yoshin Tamai Process for preparing polyprenols
US6784207B2 (en) * 2000-08-04 2004-08-31 Roche Vitamins Inc. Phytanic acid derivative compositions
CA2421026C (en) * 2001-10-16 2005-02-15 Avanir Pharmaceuticals Viral inhibition by n-docosanol
US7015022B2 (en) * 2002-06-07 2006-03-21 University Of Medicine & Dentistry Of New Jersey Mammalian catalase-dependent oxidation processes and methods for stimulating oxidative activities
US20050158329A1 (en) * 2004-01-21 2005-07-21 Ghosh Swapan K. Novel phytol derived immunoadjuvants and their use in vaccine formulations
WO2017087539A1 (en) * 2015-11-16 2017-05-26 O'neil Gregory W Alkenone-based formulations for topical applications

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53145922A (en) * 1977-05-26 1978-12-19 Eisai Co Ltd Remedy for peptic ulcer containing prenyl ketone compound
FR4055M (sv) * 1964-01-20 1966-04-04
GB1459233A (en) 1973-08-29 1976-12-22 Inst Rech Chim Biolog Medicament containing a higher alkanol
US4059641A (en) * 1975-11-18 1977-11-22 Sankyo Company Limited Polyprenyl derivatives
JPS5391137A (en) * 1977-01-19 1978-08-10 Sumitomo Chem Co Ltd Stabilization of agrichemicals
DE2834911C2 (de) * 1977-08-10 1985-11-21 Eisai Co., Ltd., Tokio/Tokyo Antihypertonikum
US4199587A (en) * 1977-08-10 1980-04-22 Eisai Co., Ltd. Method of treating hypertension with polyprenyl alcohol ester
JPS6058209B2 (ja) * 1978-12-01 1985-12-19 エーザイ株式会社 β，γ−ジヒドロポリプレニルアルコ−ルおよびそれからなる血圧降下剤
FR2443245A1 (fr) * 1978-12-07 1980-07-04 Nisshin Flour Milling Co Nouveaux agents anti-ulcere et compositions pharmaceutiques les contenant
EP0041235B1 (en) * 1980-05-30 1985-02-13 Eisai Co., Ltd. Alpha,beta-dihydropolyprenyl derivatives for treating liver diseases
CA1165240A (en) * 1980-07-09 1984-04-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
JPS5791932A (en) * 1980-11-28 1982-06-08 Kuraray Co Ltd Polyprenyl compound
DE3163920D1 (en) * 1980-12-24 1984-07-05 Eisai Co Ltd Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases
JPS57106618A (en) * 1980-12-24 1982-07-02 Eisai Co Ltd Anticancer agent consisting of polyprenyl compound
DE3318989C2 (de) * 1982-05-28 1996-11-21 Eisai Co Ltd ß,gamma-Dihydropolyprenylalkoholderivate und diese enthaltende Arzneimittel und deren Verwendung
EP0561305B1 (en) * 1992-03-17 1999-08-11 Eisai Co., Ltd. Skin whitening composition containing teprenone

Also Published As

Publication number Publication date
GB2159710A (en) 1985-12-11
DK239483A (da) 1983-11-29
ATA197283A (de) 1989-07-15
SE8303013L (sv) 1983-11-29
CH654823A5 (fr) 1986-03-14
GB8508220D0 (en) 1985-05-09
SE8801513D0 (sv) 1988-04-22
FR2532844A1 (fr) 1984-03-16
GB2122610B (en) 1987-04-01
ES522789A0 (es) 1984-09-01
FR2569108A1 (fr) 1986-02-21
FR2527597B1 (fr) 1989-02-10
GB2159711A (en) 1985-12-11
GB8508217D0 (en) 1985-05-09
US4624966A (en) 1986-11-25
GB2159710B (en) 1987-04-08
FR2532844B1 (fr) 1986-10-03
SE502924C2 (sv) 1996-02-19
SE8801514L (sv) 1988-04-22
NL8301892A (nl) 1983-12-16
DE3318989A1 (de) 1983-12-01
SE502922C2 (sv) 1996-02-19
NL194300B (nl) 2001-08-01
ES8506567A1 (es) 1985-07-16
GB2159712B (en) 1987-04-01
US6111131A (en) 2000-08-29
FR2569108B1 (fr) 1990-03-02
SE461650B (sv) 1990-03-12
GB8508219D0 (en) 1985-05-09
GB2159712A (en) 1985-12-11
SE502923C2 (sv) 1996-02-19
DE3348500C2 (de) 1998-10-22
GB2159055A (en) 1985-11-27
FR2532848B1 (fr) 1986-04-11
US6288128B1 (en) 2001-09-11
GB8314419D0 (en) 1983-06-29
FR2527597A1 (fr) 1983-12-02
ES8507444A1 (es) 1985-09-01
GB8508218D0 (en) 1985-05-09
SE8801515L (sv) 1988-04-22
AT389871B (de) 1990-02-12
SE8801515D0 (sv) 1988-04-22
ES529754A0 (es) 1985-09-01
IT1164256B (it) 1987-04-08
SE8801513L (sv) 1988-04-22
IT8321364A1 (it) 1984-11-30
GB2159054A (en) 1985-11-27
SE8801514D0 (sv) 1988-04-22
FR2532843A1 (fr) 1984-03-16
GB2122610A (en) 1984-01-18
ES529753A0 (es) 1985-07-16
GB2159054B (en) 1987-04-08
GB2159055B (en) 1987-04-08
ES8406992A1 (es) 1984-09-01
GB2159713A (en) 1985-12-11
GB2159711B (en) 1987-04-01
GB8508214D0 (en) 1985-05-09
DK171640B1 (da) 1997-03-03
IT8321364A0 (it) 1983-05-30
FR2532848A1 (fr) 1984-03-16
SE8303013D0 (sv) 1983-05-27
DE3318989C2 (de) 1996-11-21
DK239483D0 (da) 1983-05-27
CA1310660C (en) 1992-11-24

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20030527