NL193245C - Aan 1Ó,25-dihydroxyvitamine D2 verwante verbinding en farmaceutisch preparaat met een het calciummetabolisme regulerende werking dat een dergelijke verbinding bevat. - Google Patents

Aan 1Ó,25-dihydroxyvitamine D2 verwante verbinding en farmaceutisch preparaat met een het calciummetabolisme regulerende werking dat een dergelijke verbinding bevat. Download PDF

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Publication number
NL193245C
NL193245C NL8420137A NL8420137A NL193245C NL 193245 C NL193245 C NL 193245C NL 8420137 A NL8420137 A NL 8420137A NL 8420137 A NL8420137 A NL 8420137A NL 193245 C NL193245 C NL 193245C
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NL
Netherlands
Prior art keywords
compound
dihydroxyvitamin
formula
compounds
calcium
Prior art date
Application number
NL8420137A
Other languages
English (en)
Dutch (nl)
Other versions
NL193245B (nl
NL8420137A (nl
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of NL8420137A publication Critical patent/NL8420137A/nl
Publication of NL193245B publication Critical patent/NL193245B/xx
Application granted granted Critical
Publication of NL193245C publication Critical patent/NL193245C/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0042Nitrogen only

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
NL8420137A 1983-05-09 1984-05-09 Aan 1Ó,25-dihydroxyvitamine D2 verwante verbinding en farmaceutisch preparaat met een het calciummetabolisme regulerende werking dat een dergelijke verbinding bevat. NL193245C (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49286383A 1983-05-09 1983-05-09
US49286383 1983-05-09
US60732784A 1984-05-04 1984-05-04
US60732784 1984-05-04

Publications (3)

Publication Number Publication Date
NL8420137A NL8420137A (nl) 1985-04-01
NL193245B NL193245B (nl) 1998-12-01
NL193245C true NL193245C (nl) 1999-04-02

Family

ID=27050897

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8420137A NL193245C (nl) 1983-05-09 1984-05-09 Aan 1Ó,25-dihydroxyvitamine D2 verwante verbinding en farmaceutisch preparaat met een het calciummetabolisme regulerende werking dat een dergelijke verbinding bevat.

Country Status (7)

Country Link
JP (3) JPH0651624B2 (de)
AU (1) AU568549B2 (de)
CH (1) CH665834A5 (de)
DE (4) DE3490215C2 (de)
DK (3) DK171397B1 (de)
NL (1) NL193245C (de)
WO (1) WO1984004527A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3590488T (de) * 1984-10-04 1986-10-09 Wisconsin Alumni Research Foundation, Madison, Wis. Vitamin D-Derivate und Verfahren zu deren Herstellung
WO1986004333A1 (en) * 1985-01-17 1986-07-31 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
CA1341408C (en) * 1988-08-02 2002-12-10 Charles W. Bishop Method for treating and preventing loss of bone mass
US5104864A (en) * 1988-08-02 1992-04-14 Bone Care International, Inc. Method for treating and preventing loss of bone mass
US4973584A (en) * 1989-03-09 1990-11-27 Deluca Hector F Novel 1α-hydroxyvitamin D2 epimer and derivatives
JP2645130B2 (ja) * 1989-03-31 1997-08-25 日清製粉株式会社 ステロイド誘導体
GB8914963D0 (en) * 1989-06-29 1989-08-23 Leo Pharm Prod Ltd Chemical compounds
IN171426B (de) * 1990-02-14 1992-10-10 Wisconsin Alumni Res Found
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
NZ254424A (en) * 1992-06-22 1997-09-22 Lunar Corp Pharmaceutical composition and use of 1 alpha hydroxy-pre-vitamin d
US5763429A (en) 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
BR9815442A (pt) 1997-02-13 2001-08-21 Bone Care Int Inc Liberação terapêutica dirigida de compostos de vitamina d
US20090233889A1 (en) 2008-03-12 2009-09-17 Uttam Saha Stabilized 1,25-dihydroxyvitamin d2 and method of making same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4267117A (en) * 1978-06-19 1981-05-12 The Upjohn Company Compounds and process
US4269777A (en) * 1979-05-21 1981-05-26 Wisconsin Alumni Research Foundation Isotopically labeled vitamin D derivatives and processes for preparing same

Also Published As

Publication number Publication date
DK183291A (da) 1991-11-07
DK184588D0 (da) 1988-04-06
DK172733B1 (da) 1999-06-21
JPH0339505B2 (de) 1991-06-14
DK172567B1 (da) 1999-01-18
DK171397B1 (da) 1996-10-14
JPH0651624B2 (ja) 1994-07-06
DE3490215T (de) 1985-05-15
JPH02288873A (ja) 1990-11-28
DK183291D0 (da) 1991-11-07
JPH0610188B2 (ja) 1994-02-09
NL193245B (nl) 1998-12-01
DE3448412C2 (de) 1991-12-12
DK8685D0 (da) 1985-01-08
AU3011584A (en) 1984-12-04
DE3490215C2 (de) 1991-07-25
CH665834A5 (de) 1988-06-15
DK8685A (da) 1985-01-08
WO1984004527A1 (en) 1984-11-22
DK184588A (da) 1988-04-06
AU568549B2 (en) 1988-01-07
NL8420137A (nl) 1985-04-01
JPH02288854A (ja) 1990-11-28
DE3448360C2 (de) 1991-10-02
JPH02288829A (ja) 1990-11-28

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V1 Lapsed because of non-payment of the annual fee

Effective date: 20031201