NL189092C - Hybride menselijke leukocytinterferons, dubbelstrengs dna dat hiervoor codeert, expressievector, transformant micro-organisme, werkwijzen ter bereiding daarvan en farmaceutisch preparaat. - Google Patents
Hybride menselijke leukocytinterferons, dubbelstrengs dna dat hiervoor codeert, expressievector, transformant micro-organisme, werkwijzen ter bereiding daarvan en farmaceutisch preparaat.Info
- Publication number
- NL189092C NL189092C NLAANVRAGE8105078,A NL8105078A NL189092C NL 189092 C NL189092 C NL 189092C NL 8105078 A NL8105078 A NL 8105078A NL 189092 C NL189092 C NL 189092C
- Authority
- NL
- Netherlands
- Prior art keywords
- interferons
- preparation
- leukocytin
- transformant
- organism
- Prior art date
Links
- 102000014150 Interferons Human genes 0.000 title abstract 4
- 108010050904 Interferons Proteins 0.000 title abstract 4
- 229940047124 interferons Drugs 0.000 title abstract 4
- 241000282414 Homo sapiens Species 0.000 title abstract 2
- 239000013604 expression vector Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000013598 vector Substances 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20557980A | 1980-11-10 | 1980-11-10 | |
| US20557980 | 1980-11-10 | ||
| US23738881 | 1981-02-23 | ||
| US06/237,388 US4414150A (en) | 1980-11-10 | 1981-02-23 | Hybrid human leukocyte interferons |
| US06/305,657 US4456748A (en) | 1981-02-23 | 1981-09-25 | Hybrid human leukocyte interferons |
| US30565781 | 1981-09-25 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8105078A NL8105078A (nl) | 1982-06-01 |
| NL189092B NL189092B (nl) | 1992-08-03 |
| NL189092C true NL189092C (nl) | 1993-01-04 |
Family
ID=27394813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE8105078,A NL189092C (nl) | 1980-11-10 | 1981-11-10 | Hybride menselijke leukocytinterferons, dubbelstrengs dna dat hiervoor codeert, expressievector, transformant micro-organisme, werkwijzen ter bereiding daarvan en farmaceutisch preparaat. |
Country Status (34)
| Country | Link |
|---|---|
| EP (1) | EP0051873B1 (de) |
| JP (1) | JP2642291B2 (de) |
| KR (1) | KR920007439B1 (de) |
| AT (1) | ATE46718T1 (de) |
| AU (1) | AU555293B2 (de) |
| BR (1) | BR8107293A (de) |
| CA (2) | CA1212915A (de) |
| CH (2) | CH660743A5 (de) |
| DE (2) | DE3144469A1 (de) |
| DK (1) | DK173590B1 (de) |
| DO (1) | DOP1981004064A (de) |
| DZ (1) | DZ350A1 (de) |
| ES (2) | ES506955A0 (de) |
| FI (1) | FI79550C (de) |
| FR (1) | FR2493867B1 (de) |
| GB (1) | GB2090258B (de) |
| GR (1) | GR81947B (de) |
| HK (1) | HK51685A (de) |
| IE (1) | IE51850B1 (de) |
| IL (1) | IL64243A (de) |
| IT (1) | IT1169276B (de) |
| KE (1) | KE3536A (de) |
| LU (1) | LU83745A1 (de) |
| MC (1) | MC1424A1 (de) |
| MY (2) | MY8700710A (de) |
| NL (1) | NL189092C (de) |
| NO (1) | NO165201C (de) |
| NZ (1) | NZ198906A (de) |
| PH (1) | PH18565A (de) |
| PL (1) | PL233748A1 (de) |
| PT (1) | PT73955B (de) |
| SE (1) | SE460539B (de) |
| YU (1) | YU46597B (de) |
| ZW (1) | ZW26981A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH651308A5 (de) * | 1980-07-01 | 1985-09-13 | Hoffmann La Roche | Interferone und deren herstellung. |
| EP0085693A1 (de) * | 1981-08-14 | 1983-08-17 | A/S Alfred Benzon | Gegenstände betreffend menschliche interferon-alpha-subtyp-eiweissstoffe sowie übereinstimmende antikörper |
| EP0072541A3 (de) * | 1981-08-14 | 1984-04-18 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Menschliche Leukozyten-Interferone, Verfahren zu deren Mikrobiologischer Herstellung, Zwischenprodukte und diese enthaltende Zusammensetzungen |
| GB2108510B (en) * | 1981-10-03 | 1984-12-12 | Ciba Geigy Ag | Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof |
| IT1167610B (it) * | 1982-01-19 | 1987-05-13 | Cetus Corp | Interfreron ibrido multiclasse, composizione farmaceutica che lo contiene e procedimento di produzione |
| DE3220116A1 (de) * | 1982-05-28 | 1983-12-01 | Dr. Karl Thomae Gmbh, 7950 Biberach | Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung |
| IE56509B1 (en) * | 1982-11-04 | 1991-08-28 | Univ California | Methods for oncogenic detection |
| US4751287A (en) * | 1983-02-24 | 1988-06-14 | Institut Organicheskogo Sinteza Akademii Nauk Latviiskoi Ssr | Human leukocyte interferon N and a method of producing same in bacterial cells |
| GB8315980D0 (en) * | 1983-06-10 | 1983-07-13 | Biogen Nv | Producing hybrid dna sequences |
| GB8317880D0 (en) * | 1983-07-01 | 1983-08-03 | Searle & Co | Structure and synthesis of interferons |
| US4892743A (en) * | 1983-12-21 | 1990-01-09 | Schering Corporation | Novel hybrid interferon species |
| EP0146903A3 (de) * | 1983-12-19 | 1987-07-22 | Schering Corporation | Herstellung eines ein Hybrid-Interferon-Spezies kodierenden Vektors |
| DE3409966A1 (de) * | 1984-03-19 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | Gentechnologisches verfahren zur herstellung von human-gammainterferon und mittel zur durchfuehrung dieses verfahrens |
| JPS6156199A (ja) * | 1984-08-27 | 1986-03-20 | Shionogi & Co Ltd | 新規ヒトインタ−フエロンα類 |
| EP0173935A1 (de) * | 1984-08-31 | 1986-03-12 | University Patents, Inc. | Hybrid-Lymphoblastoid-Leukozyten-Humaninterferone |
| DE3434345A1 (de) * | 1984-09-19 | 1986-03-27 | Hoechst Ag, 6230 Frankfurt | Verwendung von (alpha)-interferonen zur bekaempfung von durchfaellen |
| EP0194006B1 (de) * | 1985-02-01 | 1992-04-29 | Imperial Chemical Industries Plc | Analoge Interferon-Polypeptide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
| DE3685996T2 (de) * | 1985-06-11 | 1993-01-14 | Ciba Geigy Ag | Hybrid-interferone. |
| WO1987002037A1 (en) * | 1985-09-26 | 1987-04-09 | Genetics Institute, Inc. | Pulmonary surfactant proteins |
| US4806347A (en) * | 1985-12-11 | 1989-02-21 | Schering Corporation | Interferon combinations |
| EP0490233A1 (de) * | 1986-03-10 | 1992-06-17 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung |
| DE3607835A1 (de) * | 1986-03-10 | 1987-09-24 | Boehringer Ingelheim Int | Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung |
| US4851220A (en) * | 1986-11-26 | 1989-07-25 | Schering Corporation | Stable oleaginous gel |
| US4853218A (en) * | 1987-02-24 | 1989-08-01 | Schering Corporation | Zinc-protamine-alpha interferon complex |
| EP0331635A3 (de) * | 1988-02-29 | 1990-02-28 | The Board of Regents of the University of Texas System | Zubereitungen zur Behandlung von Blasenkrebs. |
| US5372808A (en) † | 1990-10-17 | 1994-12-13 | Amgen Inc. | Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect |
| GB2273931A (en) * | 1992-09-28 | 1994-07-06 | Unilever Plc | Mutant polypeptides |
| JPH11507352A (ja) | 1995-06-07 | 1999-06-29 | ジンタ・インコーポレイテッド | 新規カルバメート基本カチオン性脂質 |
| TW442492B (en) * | 1995-07-26 | 2001-06-23 | Novartis Ag | Process for the enrichment of interferon |
| FR2823220B1 (fr) | 2001-04-04 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo) |
| CA2498319A1 (en) | 2002-09-09 | 2004-03-18 | Nautilus Biotech | Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules |
| US7314613B2 (en) | 2002-11-18 | 2008-01-01 | Maxygen, Inc. | Interferon-alpha polypeptides and conjugates |
| CA2566247A1 (en) | 2004-05-19 | 2005-12-01 | Maxygen, Inc. | Interferon-alpha polypeptides and conjugates |
| MX2007014524A (es) | 2005-05-18 | 2008-02-07 | Maxygen Inc | Polipeptidos desarrollados de interferon-alfa. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CY1346A (en) * | 1980-01-08 | 1987-01-16 | Biogen Nv | Dna sequences,recombinant dna molecules and processes for producing human interferon-like polypeptides |
-
1981
- 1981-11-07 ES ES506955A patent/ES506955A0/es active Granted
- 1981-11-09 EP EP81109579A patent/EP0051873B1/de not_active Expired
- 1981-11-09 GR GR66464A patent/GR81947B/el unknown
- 1981-11-09 DE DE19813144469 patent/DE3144469A1/de not_active Ceased
- 1981-11-09 IL IL64243A patent/IL64243A/xx not_active IP Right Cessation
- 1981-11-09 MC MC811558A patent/MC1424A1/fr unknown
- 1981-11-09 DE DE8181109579T patent/DE3177106D1/de not_active Expired
- 1981-11-09 PT PT73955A patent/PT73955B/pt unknown
- 1981-11-09 CA CA000389688A patent/CA1212915A/en not_active Expired
- 1981-11-09 PL PL23374881A patent/PL233748A1/xx unknown
- 1981-11-09 IE IE2622/81A patent/IE51850B1/en not_active IP Right Cessation
- 1981-11-09 AU AU77304/81A patent/AU555293B2/en not_active Expired
- 1981-11-09 GB GB8133762A patent/GB2090258B/en not_active Expired
- 1981-11-09 CH CH7174/81A patent/CH660743A5/de not_active IP Right Cessation
- 1981-11-09 FR FR8120943A patent/FR2493867B1/fr not_active Expired
- 1981-11-09 DK DK198104946A patent/DK173590B1/da active
- 1981-11-09 NZ NZ198906A patent/NZ198906A/en unknown
- 1981-11-09 SE SE8106641A patent/SE460539B/sv not_active Application Discontinuation
- 1981-11-09 DZ DZ816369A patent/DZ350A1/fr active
- 1981-11-09 NO NO813785A patent/NO165201C/no not_active IP Right Cessation
- 1981-11-09 CH CH5574/85A patent/CH663032A5/de not_active IP Right Cessation
- 1981-11-09 PH PH26462A patent/PH18565A/en unknown
- 1981-11-09 AT AT81109579T patent/ATE46718T1/de not_active IP Right Cessation
- 1981-11-10 ZW ZW269/81A patent/ZW26981A1/xx unknown
- 1981-11-10 KR KR1019810004343A patent/KR920007439B1/ko not_active Expired
- 1981-11-10 YU YU265681A patent/YU46597B/sh unknown
- 1981-11-10 IT IT24967/81A patent/IT1169276B/it active
- 1981-11-10 LU LU83745A patent/LU83745A1/de unknown
- 1981-11-10 DO DO1981004064A patent/DOP1981004064A/es unknown
- 1981-11-10 FI FI813539A patent/FI79550C/fi not_active IP Right Cessation
- 1981-11-10 BR BR8107293A patent/BR8107293A/pt unknown
- 1981-11-10 NL NLAANVRAGE8105078,A patent/NL189092C/xx not_active IP Right Cessation
-
1982
- 1982-05-19 ES ES512354A patent/ES512354A0/es active Granted
-
1984
- 1984-12-18 CA CA000470467A patent/CA1277616C/en not_active Expired - Lifetime
-
1985
- 1985-05-21 KE KE3536A patent/KE3536A/xx unknown
- 1985-07-04 HK HK516/85A patent/HK51685A/xx not_active IP Right Cessation
-
1987
- 1987-12-30 MY MY710/87A patent/MY8700710A/xx unknown
-
1988
- 1988-12-30 MY MY66/88A patent/MY8800066A/xx unknown
-
1992
- 1992-12-28 JP JP4349148A patent/JP2642291B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL189092B (nl) | Hybride menselijke leukocytinterferons, dubbelstrengs dna dat hiervoor codeert, expressievector, transformant micro-organisme, werkwijzen ter bereiding daarvan en farmaceutisch preparaat. | |
| SE8105657L (sv) | Mikrobiell framstellning av humanfibroblastinterferon | |
| HK49285A (en) | Interferons and process for their preparation | |
| PT97316A (pt) | Sequencias de dna,construcoes de dna e metodo para a sua aplicacao no tratamento de doencas celulares proliferativas | |
| ATE69241T1 (de) | Herstellung von polypeptiden mit humangammainterferon-aktivitaet. | |
| DE3683267D1 (de) | Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung. | |
| NO177863C (no) | Fremgangsmåte for fremstilling av rekombinant humant IFN-type I, IFN1, IFN-pseudo-2, -3, og -4, samt ekspresjonsvektorer | |
| HUT40695A (en) | Dna sequences, recombinant dna molecules and processes for preparing humane lipocortine like polypeptides | |
| EP0072541A3 (de) | Menschliche Leukozyten-Interferone, Verfahren zu deren Mikrobiologischer Herstellung, Zwischenprodukte und diese enthaltende Zusammensetzungen | |
| NO890174L (no) | Rekombinante interleukin-1alfa-polypeptider. | |
| ATE181104T1 (de) | Isoliertes pctd plasmid aus chlamydia trachomatis von serotyp d, dessen genen und davon kodierten proteine, rekombinante plasmide für die expression von deren genen als fusionsproteine in einem keterologen system, und ihre verwendung als impfstoff- und/oder diagnostiekformulierung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| V1 | Lapsed because of non-payment of the annual fee |
Effective date: 19970601 |