IT8124967A0 - Interferoni di leucociti umani ibridi. - Google Patents

Interferoni di leucociti umani ibridi.

Info

Publication number
IT8124967A0
IT8124967A0 IT8124967A IT2496781A IT8124967A0 IT 8124967 A0 IT8124967 A0 IT 8124967A0 IT 8124967 A IT8124967 A IT 8124967A IT 2496781 A IT2496781 A IT 2496781A IT 8124967 A0 IT8124967 A0 IT 8124967A0
Authority
IT
Italy
Prior art keywords
human leukocyte
hybrid human
leukocyte interferons
interferons
hybrid
Prior art date
Application number
IT8124967A
Other languages
English (en)
Other versions
IT1169276B (it
Inventor
David Van Norman Goeddel
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/237,388 external-priority patent/US4414150A/en
Priority claimed from US06/305,657 external-priority patent/US4456748A/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IT8124967A0 publication Critical patent/IT8124967A0/it
Application granted granted Critical
Publication of IT1169276B publication Critical patent/IT1169276B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/71Expression systems using regulatory sequences derived from the trp-operon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
IT24967/81A 1980-11-10 1981-11-10 Interferoni di leucociti umani ibridi IT1169276B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20557980A 1980-11-10 1980-11-10
US06/237,388 US4414150A (en) 1980-11-10 1981-02-23 Hybrid human leukocyte interferons
US06/305,657 US4456748A (en) 1981-02-23 1981-09-25 Hybrid human leukocyte interferons

Publications (2)

Publication Number Publication Date
IT8124967A0 true IT8124967A0 (it) 1981-11-10
IT1169276B IT1169276B (it) 1987-05-27

Family

ID=27394813

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24967/81A IT1169276B (it) 1980-11-10 1981-11-10 Interferoni di leucociti umani ibridi

Country Status (34)

Country Link
EP (1) EP0051873B1 (it)
JP (1) JP2642291B2 (it)
KR (1) KR920007439B1 (it)
AT (1) ATE46718T1 (it)
AU (1) AU555293B2 (it)
BR (1) BR8107293A (it)
CA (2) CA1212915A (it)
CH (2) CH660743A5 (it)
DE (2) DE3177106D1 (it)
DK (1) DK173590B1 (it)
DO (1) DOP1981004064A (it)
DZ (1) DZ350A1 (it)
ES (2) ES8302778A1 (it)
FI (1) FI79550C (it)
FR (1) FR2493867B1 (it)
GB (1) GB2090258B (it)
GR (1) GR81947B (it)
HK (1) HK51685A (it)
IE (1) IE51850B1 (it)
IL (1) IL64243A (it)
IT (1) IT1169276B (it)
KE (1) KE3536A (it)
LU (1) LU83745A1 (it)
MC (1) MC1424A1 (it)
MY (2) MY8700710A (it)
NL (1) NL189092C (it)
NO (1) NO165201C (it)
NZ (1) NZ198906A (it)
PH (1) PH18565A (it)
PL (1) PL233748A1 (it)
PT (1) PT73955B (it)
SE (1) SE460539B (it)
YU (1) YU46597B (it)
ZW (1) ZW26981A1 (it)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH651308A5 (de) * 1980-07-01 1985-09-13 Hoffmann La Roche Interferone und deren herstellung.
EP0072541A3 (en) * 1981-08-14 1984-04-18 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Human leukocyte interferons, process for their microbial production, intermediates therefor and compositions containing them
JPS58501543A (ja) * 1981-08-14 1983-09-16 エイ/エス アルフレツド ベンツオン ヒトインタ−フエロン蛋白とヒトインタ−フエロン蛋白に対する抗体に関する改良
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
EP0098876A1 (en) * 1982-01-19 1984-01-25 Cetus Corporation Multiclass hybrid interferons
DE3220116A1 (de) * 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung
IE56509B1 (en) * 1982-11-04 1991-08-28 Univ California Methods for oncogenic detection
FR2541579B1 (fr) * 1983-02-24 1987-12-18 Inst Organicheskogo Sinteza Ak Interferon n leucocytaire humain et procede d'obtention de celui-ci dans les cellules bacteriennes
GB8315980D0 (en) * 1983-06-10 1983-07-13 Biogen Nv Producing hybrid dna sequences
GB8317880D0 (en) * 1983-07-01 1983-08-03 Searle & Co Structure and synthesis of interferons
EP0146903A3 (en) * 1983-12-19 1987-07-22 Schering Corporation Production of a vector encoding a novel hybrid interferon species
US4892743A (en) * 1983-12-21 1990-01-09 Schering Corporation Novel hybrid interferon species
DE3409966A1 (de) * 1984-03-19 1985-09-26 Hoechst Ag, 6230 Frankfurt Gentechnologisches verfahren zur herstellung von human-gammainterferon und mittel zur durchfuehrung dieses verfahrens
JPS6156199A (ja) * 1984-08-27 1986-03-20 Shionogi & Co Ltd 新規ヒトインタ−フエロンα類
EP0173935A1 (en) * 1984-08-31 1986-03-12 University Patents, Inc. Hybrid lymphoblastoid-leukocyte human interferons
DE3434345A1 (de) * 1984-09-19 1986-03-27 Hoechst Ag, 6230 Frankfurt Verwendung von (alpha)-interferonen zur bekaempfung von durchfaellen
EP0194006B1 (en) * 1985-02-01 1992-04-29 Imperial Chemical Industries Plc Analogous interferon polypeptides, process for their preparation and pharmaceutical compositions containing them
US4885166A (en) * 1985-06-11 1989-12-05 Ciba-Geigy Corporation Hybrid interferons
WO1987002037A1 (en) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Pulmonary surfactant proteins
US4806347A (en) * 1985-12-11 1989-02-21 Schering Corporation Interferon combinations
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
US4851220A (en) * 1986-11-26 1989-07-25 Schering Corporation Stable oleaginous gel
US4853218A (en) * 1987-02-24 1989-08-01 Schering Corporation Zinc-protamine-alpha interferon complex
EP0331635A3 (en) * 1988-02-29 1990-02-28 The Board of Regents of the University of Texas System Preparations for treating bladder cancer
US5372808A (en) 1990-10-17 1994-12-13 Amgen Inc. Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect
GB2273931A (en) * 1992-09-28 1994-07-06 Unilever Plc Mutant polypeptides
CA2223088A1 (en) 1995-06-07 1996-12-19 Bob Dale Brown Novel carbamate-based cationic lipids
TW442492B (en) * 1995-07-26 2001-06-23 Novartis Ag Process for the enrichment of interferon
FR2823220B1 (fr) 2001-04-04 2003-12-12 Genodyssee Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
US7314613B2 (en) 2002-11-18 2008-01-01 Maxygen, Inc. Interferon-alpha polypeptides and conjugates
JP2008507298A (ja) 2004-05-19 2008-03-13 マキシジェン, インコーポレイテッド インターフェロンαポリペプチドおよび結合体
MX2007014524A (es) 2005-05-18 2008-02-07 Maxygen Inc Polipeptidos desarrollados de interferon-alfa.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR73557B (it) * 1980-01-08 1984-03-15 Biogen Inc

Also Published As

Publication number Publication date
ATE46718T1 (de) 1989-10-15
FI813539L (fi) 1982-05-11
NL189092C (nl) 1993-01-04
FR2493867A1 (fr) 1982-05-14
LU83745A1 (de) 1983-09-01
CA1212915A (en) 1986-10-21
IE51850B1 (en) 1987-04-15
NO813785L (no) 1982-05-11
IL64243A0 (en) 1982-02-28
PT73955B (en) 1983-11-23
KR920007439B1 (ko) 1992-09-01
BR8107293A (pt) 1982-08-03
NZ198906A (en) 1985-12-13
HK51685A (en) 1985-07-12
SE460539B (sv) 1989-10-23
ES506955A0 (es) 1983-02-01
JPH07308191A (ja) 1995-11-28
CH663032A5 (de) 1987-11-13
EP0051873A2 (en) 1982-05-19
DE3144469A1 (de) 1982-09-02
EP0051873B1 (en) 1989-09-27
KR830007825A (ko) 1983-11-07
PH18565A (en) 1985-08-09
FI79550B (fi) 1989-09-29
GB2090258B (en) 1984-05-02
NL8105078A (nl) 1982-06-01
MC1424A1 (fr) 1982-10-18
MY8700710A (en) 1987-12-31
JP2642291B2 (ja) 1997-08-20
ES8304200A1 (es) 1983-03-01
IT1169276B (it) 1987-05-27
KE3536A (en) 1985-06-07
AU7730481A (en) 1982-05-20
FI79550C (fi) 1990-01-10
NO165201C (no) 1991-01-16
AU555293B2 (en) 1986-09-18
DK173590B1 (da) 2001-04-02
NO165201B (no) 1990-10-01
FR2493867B1 (fr) 1986-06-27
GR81947B (it) 1984-12-12
NL189092B (nl) 1992-08-03
ES8302778A1 (es) 1983-02-01
CA1277616C (en) 1990-12-11
GB2090258A (en) 1982-07-07
ZW26981A1 (en) 1982-06-02
IL64243A (en) 1985-11-29
DE3177106D1 (en) 1989-11-02
SE8106641L (sv) 1982-06-24
PL233748A1 (en) 1983-07-18
IE812622L (en) 1982-05-10
DK494681A (da) 1982-05-11
ES512354A0 (es) 1983-03-01
PT73955A (en) 1981-12-01
MY8800066A (en) 1988-12-31
DZ350A1 (fr) 2004-09-13
CH660743A5 (de) 1987-06-15
YU265681A (en) 1984-08-31
DOP1981004064A (es) 1988-03-16
YU46597B (sh) 1994-01-20
EP0051873A3 (en) 1982-09-22

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971127