MY8500285A - 3-(1-imidazolylalry) indoles - Google Patents

3-(1-imidazolylalry) indoles

Info

Publication number
MY8500285A
MY8500285A MY285/85A MY8500285A MY8500285A MY 8500285 A MY8500285 A MY 8500285A MY 285/85 A MY285/85 A MY 285/85A MY 8500285 A MY8500285 A MY 8500285A MY 8500285 A MY8500285 A MY 8500285A
Authority
MY
Malaysia
Prior art keywords
imidazolylalry
indoles
Prior art date
Application number
MY285/85A
Other languages
English (en)
Inventor
Peter Edward Cross
Roger Peter Dickenson
Original Assignee
Pfizer Limited Kent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Limited Kent filed Critical Pfizer Limited Kent
Publication of MY8500285A publication Critical patent/MY8500285A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MY285/85A 1979-03-07 1985-12-30 3-(1-imidazolylalry) indoles MY8500285A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7908123 1979-03-07

Publications (1)

Publication Number Publication Date
MY8500285A true MY8500285A (en) 1985-12-31

Family

ID=10503707

Family Applications (1)

Application Number Title Priority Date Filing Date
MY285/85A MY8500285A (en) 1979-03-07 1985-12-30 3-(1-imidazolylalry) indoles

Country Status (36)

Country Link
US (1) US4273782A (nl)
JP (1) JPS55133380A (nl)
KR (1) KR850000760B1 (nl)
AR (1) AR227015A1 (nl)
AT (1) AT375366B (nl)
AU (1) AU516957B2 (nl)
BE (1) BE882113A (nl)
CA (1) CA1120479A (nl)
CH (1) CH649546A5 (nl)
CS (1) CS253702B2 (nl)
DD (1) DD149525A5 (nl)
DE (1) DE3008632A1 (nl)
DK (1) DK151884C (nl)
ES (2) ES8104278A1 (nl)
FI (1) FI66860C (nl)
FR (1) FR2450832A1 (nl)
GR (1) GR67237B (nl)
HK (1) HK89884A (nl)
HU (1) HU184727B (nl)
IE (1) IE49542B1 (nl)
IL (1) IL59524A (nl)
IT (1) IT1218420B (nl)
KE (1) KE3467A (nl)
LU (1) LU82224A1 (nl)
MY (1) MY8500285A (nl)
NL (1) NL182959C (nl)
NO (1) NO152217C (nl)
NZ (1) NZ193052A (nl)
PH (1) PH15198A (nl)
PL (1) PL128296B1 (nl)
PT (1) PT70914A (nl)
SE (1) SE440778B (nl)
SG (1) SG67284G (nl)
SU (1) SU1277894A3 (nl)
YU (1) YU41911B (nl)
ZA (1) ZA801328B (nl)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4414159A (en) * 1980-09-26 1983-11-08 E. I. Du Pont De Nemours & Co. Vinyl ether monomers and polymers therefrom
US4444775A (en) * 1981-06-22 1984-04-24 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridines
KR840000529A (ko) * 1981-07-07 1984-02-25 콘스탄틴 루이스 클레멘트 인돌 유도체의 제조방법
ZA825413B (en) * 1981-08-26 1983-06-29 Pfizer Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4436746A (en) 1982-09-30 1984-03-13 Ciba-Geigy Corporation Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles
US4539410A (en) * 1982-09-30 1985-09-03 Ciba-Geigy Corporation N-Substituted-2-(1-imidazolyl)indoles
AT376436B (de) * 1982-11-05 1984-11-26 Laevosan Gmbh & Co Kg Verfahren zur herstellung neuer thiophen-2carbons[urederivate und pharmazeutisch vertraeglicher saeure- oder basenadditionssalze davon
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
ATE90076T1 (de) 1986-03-27 1993-06-15 Merck Frosst Canada Inc Tetrahydrocarbazole ester.
JPH0832679B2 (ja) * 1986-09-05 1996-03-29 理化学研究所 Ｎ―フタルイシド誘導体及びその製造法
GR871809B (en) * 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones
KR920700210A (ko) * 1989-03-31 1992-02-19 기따미 가즈히꼬 신규 이미다졸 유도체, 그의 제법 및 그의 의약용도
DE4023215A1 (de) * 1990-07-21 1992-01-23 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
CA2091246A1 (en) * 1990-09-13 1992-03-14 Ian Thomson Forbes Indole ureas as 5 ht receptor antagonist
US5162337A (en) * 1990-10-05 1992-11-10 Merck & Co., Inc. Animal growth promotion
US5120749A (en) * 1991-02-20 1992-06-09 Abbott Laboratories Platelet activating antagonists
WO1993012108A1 (en) * 1991-12-18 1993-06-24 Schering Corporation Imidazolyl or imidazoylalkyl substituted with a four or five membered nitrogen containing heterocyclic ring
CA2109931A1 (en) * 1992-03-27 1993-10-14 Hiroshi Matsui Novel imidazole derivative, pharmaceutical use thereof, and intermediate therefor
US5538973A (en) * 1992-03-27 1996-07-23 Kyoto Pharmaceutical Industries, Ltd. Imidazole derivative, pharmaceutical use thereof, and intermediate therefor
JPH0632913U (ja) * 1992-09-18 1994-04-28 三洋電機株式会社 床暖房用パネル
CN1205207C (zh) * 1998-03-31 2005-06-08 药品发现学会公司 取代的吲哚链烷酸
ES2268480T3 (es) * 2002-12-10 2007-03-16 Wyeth Derivados del acido 3-alquilo- y 3-arilalquilo-1h-indol-1-il-acetico sustituidos como inhibidores del inhibidor del activador del plasminogeno-1 (pai-1).
GB0324763D0 (en) 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
AU2005296305A1 (en) * 2004-10-12 2006-04-27 Decode Genetics Ehf Sulfonamide peri-substituted bicyclics for occlusive artery disease
WO2007024944A1 (en) * 2005-08-25 2007-03-01 Schering Corporation Imidazole derivatives as functionally selective alpha2c adrenoreceptor agonists
US7977359B2 (en) * 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) * 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) * 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
EP2027117A2 (en) * 2006-05-16 2009-02-25 Decode Genetics EHF Process for preparing 7-(acryloyl)-indoles
EP2046740B1 (en) 2006-07-22 2012-05-23 Oxagen Limited Compounds having crth2 antagonist activity
TW200920369A (en) * 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
CA2708281A1 (en) 2007-12-11 2009-08-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
US7750027B2 (en) 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
PT2250161E (pt) 2008-01-18 2014-01-21 Atopix Therapeutics Ltd Compostos tendo atividade antagonista de crth2
JP2011509990A (ja) * 2008-01-22 2011-03-31 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
EP2240444A1 (en) * 2008-01-22 2010-10-20 Oxagen Limited Compounds having crth2 antagonist activity
KR20160129109A (ko) * 2008-05-23 2016-11-08 아미라 파마슈티칼스 인코포레이티드 5-리폭시게나아제 활성화 단백질 억제제
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
WO2012177782A1 (en) * 2011-06-20 2012-12-27 Myrexis, Inc. Compounds and therapeutic uses thereof
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407807D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407820D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
US11530186B2 (en) * 2018-03-29 2022-12-20 H. Lee Moffitt Cancer Center and Research Center Institute, Inc. Inhibitors for the β-catenin / T-cell factor protein-protein interaction

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL125443C (nl) * 1963-06-06
US3370063A (en) * 1964-10-05 1968-02-20 Mcneilab Inc Substituted dimethoxy indoles and method of making the same
US3621027A (en) * 1968-03-18 1971-11-16 Endo Lab 1-aminoalkyl-2,6-diaryl 4,5,6,7 tetrahydro-4-oxindales
US3931229A (en) * 1973-08-23 1976-01-06 Warner-Lambert Company 3-Thiomethyl-2[2-(dialkylamino)ethyl]indoles
US4059583A (en) * 1975-11-13 1977-11-22 Mcneil Laboratories, Incorporated Substituted indoles
AU523536B2 (en) * 1977-08-26 1982-08-05 Wellcome Foundation Limited, The Imidazoles and methods of preparing them
US4140858A (en) * 1977-12-19 1979-02-20 Warner-Lambert Company 3-(1H-imidazol-1-ylmethyl)-2-(disubstitutedaminomethyl)indoles and a method for their production
DE2960547D1 (en) * 1978-02-24 1981-11-05 Pfizer Ltd 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them

Also Published As

Publication number Publication date
NO800650L (no) 1980-09-08
KR850000760B1 (ko) 1985-05-25
SE440778B (sv) 1985-08-19
ES8205789A1 (es) 1982-08-01
SE8001736L (sv) 1980-09-08
ATA125780A (de) 1983-12-15
NL8001351A (nl) 1980-09-09
IE49542B1 (en) 1985-10-30
CS253702B2 (en) 1987-12-17
DK151884C (da) 1988-06-13
ZA801328B (en) 1981-03-25
SU1277894A3 (ru) 1986-12-15
AU516957B2 (en) 1981-07-02
FI66860C (fi) 1984-12-10
HU184727B (en) 1984-10-29
FI66860B (fi) 1984-08-31
GR67237B (nl) 1981-06-25
LU82224A1 (fr) 1980-06-06
NO152217B (no) 1985-05-13
IL59524A (en) 1982-11-30
IT1218420B (it) 1990-04-19
DD149525A5 (de) 1981-07-15
DE3008632C2 (nl) 1988-02-25
NZ193052A (en) 1984-07-06
HK89884A (en) 1984-11-23
YU61480A (en) 1983-12-31
DK151884B (da) 1988-01-11
PL128296B1 (en) 1984-01-31
KR830001928A (ko) 1983-05-19
NL182959C (nl) 1988-06-16
YU41911B (en) 1988-02-29
PT70914A (en) 1980-04-01
ES489220A0 (es) 1981-04-01
ES496889A0 (es) 1982-08-01
FI800672A (fi) 1980-09-08
FR2450832A1 (fr) 1980-10-03
FR2450832B1 (nl) 1983-04-22
CH649546A5 (de) 1985-05-31
KE3467A (en) 1984-11-09
IL59524A0 (en) 1980-06-30
PL222470A1 (nl) 1980-12-01
ES8104278A1 (es) 1981-04-01
IT8020399A0 (it) 1980-03-06
AR227015A1 (es) 1982-09-15
DK42580A (da) 1980-09-08
AU5623180A (en) 1980-09-11
JPS55133380A (en) 1980-10-17
PH15198A (en) 1982-09-17
US4273782A (en) 1981-06-16
NO152217C (no) 1985-08-21
CA1120479A (en) 1982-03-23
DE3008632A1 (de) 1980-10-16
SG67284G (en) 1985-03-15
BE882113A (fr) 1980-09-08
JPS6141513B2 (nl) 1986-09-16
IE800453L (en) 1980-09-07
AT375366B (de) 1984-07-25

Similar Documents

Publication Publication Date Title
KE3467A (en) 3-(1-imidazolyalkyl)indoles
AU539414B2 (en) 2-carboxylic azabicydoalkanes
DE3070816D1 (en) Loud-speaker
GB2046409B (en) Practice shell
AU525296B2 (en) 3-(pyrid-3-3-or4-ylankyl) indoles
GB2043639B (en) 3-optionally substituted methyl-2-penem derivatives
GB2041925B (en) 2-substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3-b)indoles
BG31792A3 (en) Fungeous means
JPS55103594A (en) Highhhat cymbals
JPS5699413A (en) Cardiovascularly active indole derivative
GB2031882B (en) Indole derivatives
ZA807102B (en) Novel halophenyl-pyridyl-allylamine derivatives
GB2055815B (en) Indoles
CU35300A (en) Pyrrholidine derivatives
GB2040697B (en) Swing
JPS55135831A (en) Improved stepprepetion projectionnmatching exposer
NZ196789A (en) 3-(n-phenyl-n-isoxazolylcarbonyl) aminotetrahydro-furan-2-ones
MW4680A1 (en) Substituted indoline-2-one derivatives
IE790554L (en) 3-(imidazol-1-ylalkyl) indoles
AU5973980A (en) Indolines
JPS55130997A (en) Fortimycin an
JPS5511559A (en) Indole derivative
NZ194686A (en) Substituted 2-carbamoyloxyimino-butanes
JPS5551067A (en) Indole derivative
JPS55163158A (en) Lid