MY8500062A - 1,2,4-troazome deriovatives, process for preparing such compounds and pharmaceutical compositions containing them - Google Patents

1,2,4-troazome deriovatives, process for preparing such compounds and pharmaceutical compositions containing them

Info

Publication number
MY8500062A
MY8500062A MY62/85A MY8500062A MY8500062A MY 8500062 A MY8500062 A MY 8500062A MY 62/85 A MY62/85 A MY 62/85A MY 8500062 A MY8500062 A MY 8500062A MY 8500062 A MY8500062 A MY 8500062A
Authority
MY
Malaysia
Prior art keywords
troazome
deriovatives
preparing
compounds
pharmaceutical compositions
Prior art date
Application number
MY62/85A
Other languages
English (en)
Inventor
Martin Gerge Baxter
Albert Reginald Elphick
Alistair Ainslie Miller
David Alan Sawyer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10505597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY8500062(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MY8500062A publication Critical patent/MY8500062A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MY62/85A 1979-06-01 1985-12-30 1,2,4-troazome deriovatives, process for preparing such compounds and pharmaceutical compositions containing them MY8500062A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7919257 1979-06-01

Publications (1)

Publication Number Publication Date
MY8500062A true MY8500062A (en) 1985-12-31

Family

ID=10505597

Family Applications (1)

Application Number Title Priority Date Filing Date
MY62/85A MY8500062A (en) 1979-06-01 1985-12-30 1,2,4-troazome deriovatives, process for preparing such compounds and pharmaceutical compositions containing them

Country Status (30)

Country Link
US (2) US4486354A (uk)
EP (2) EP0059987B1 (uk)
JP (2) JPS5625169A (uk)
AR (1) AR227521A1 (uk)
AT (1) AT370097B (uk)
AU (2) AU530999B2 (uk)
BG (1) BG60427B2 (uk)
CA (1) CA1112643A (uk)
CS (1) CS234018B2 (uk)
CZ (1) CZ384891A3 (uk)
DD (1) DD151309A5 (uk)
DK (1) DK153787C (uk)
ES (1) ES491998A0 (uk)
FI (1) FI67844C (uk)
GE (1) GEP19960470B (uk)
GR (1) GR68380B (uk)
HU (1) HU182086B (uk)
IE (1) IE49823B1 (uk)
IL (1) IL60201A (uk)
IT (1) IT1147087B (uk)
MX (1) MX9202962A (uk)
MY (1) MY8500062A (uk)
NL (1) NL950007I2 (uk)
NZ (1) NZ193890A (uk)
PL (1) PL124029B1 (uk)
SU (1) SU1055331A3 (uk)
UA (1) UA5576A1 (uk)
YU (1) YU145680A (uk)
ZA (1) ZA803250B (uk)
ZW (1) ZW12980A1 (uk)

Families Citing this family (90)

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IT1145308B (it) * 1979-08-16 1986-11-05 Wellcome Found Composti aromatici sostituiti
GB8328757D0 (en) * 1983-10-27 1983-11-30 Wellcome Found Chemical compounds
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GB8613183D0 (en) * 1986-05-30 1986-07-02 Wellcome Found Triazine salt
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US5136080A (en) * 1989-12-04 1992-08-04 Burroughs Wellcome Co. Nitrile compounds
GB9012311D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
GB9012312D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
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GB9124807D0 (en) * 1991-11-22 1992-01-15 Wellcome Found Pharmaceutical formulations
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
GB9203483D0 (en) * 1992-02-19 1992-04-08 Wellcome Found Anti-inflammatory compounds
IL105986A (en) * 1992-06-12 1998-12-06 Wellcome Found Pharmaceutical preparations containing triazine compounds for the prevention or reduction of tolerable dependence or the opposite of dependency
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
FR2699077B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes.
US6133299A (en) * 1993-02-25 2000-10-17 Warner-Lambert Company Methods for treating neurodegenerative diseases and disorders using N-(2,6-disubstituted aromatic)-N'-pyridinyl ureas and other anticonvulsant compounds
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GB9317146D0 (en) * 1993-08-18 1993-10-06 Wellcome Found Therapeutic combinations
GB9424766D0 (en) * 1994-12-07 1995-02-08 Wellcome Found Pharmaceutical composition
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GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
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US20020055177A1 (en) * 1999-03-10 2002-05-09 Glaxo Wellcome Inc. Compound and its use
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EP1603889A1 (en) * 2003-03-17 2005-12-14 Hetero Drugs Limited Novel crystalline forms of lamotrigine
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BRPI0410271A (pt) 2003-05-16 2006-05-16 Pfizer Prod Inc combinações terapêuticas de antipsicóticos atìpicos com moduladores de gaba, anticonvulsivantes ou benzodiazepinas
WO2004103340A1 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited Water dispersible tablets of lamotrigine
GB2395483A (en) * 2003-07-03 2004-05-26 Jubilant Organosys Ltd Crystalline lamotrigine and its monohydrate
CA2548917C (en) 2003-12-11 2014-09-23 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
EP1737466A1 (en) * 2004-01-29 2007-01-03 Pfizer Products Inc. COMBINATION OF y-AMINOBUTYRIC ACID MODULATORS AND 5-HT-1b RECEPTOR ANTAGONISTS
WO2005102366A2 (en) * 2004-04-19 2005-11-03 Philip Maxwell Satow Lithium combinations, and uses related thereto
PT1809271E (pt) * 2004-09-10 2010-08-30 Newron Pharm Spa Utilização de (halogenobenziloxi)benzilamino-propanamidas para o fabrico de medicamentos activos como moduladores selectivos dos canais de sódio e/ou de cálcio
US7825151B2 (en) * 2005-09-23 2010-11-02 Janssen Pharmaceutica Nv Hexahydro-cyclooctyl pyrazole cannabinoid modulators
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US8378117B2 (en) * 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
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US20070117858A1 (en) * 2005-11-23 2007-05-24 Mingde Xia Substituted 5-heteroaryl-1-phenyl-pyrazole cannabinoid modulators
US7526911B2 (en) * 2006-02-03 2009-05-05 Rolls-Royce Corporation Gas turbine engine fuel system with fuel metering valve
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GB2471729A (en) 2009-07-08 2011-01-12 Univ Greenwich 1,2,4-triazine derivatives and their use as sodium channel blockers
GB2471713A (en) 2009-07-08 2011-01-12 Univ Greenwich 1,2,4-triazine derivatives and their use as sodium channel blockers
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TWI826531B (zh) 2018-09-21 2023-12-21 南韓商愛思開生物製藥股份有限公司 具有㗁二唑之化合物及包含該化合物之醫藥組合物

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GB759014A (en) * 1952-02-26 1956-10-10 Wellcome Found Improvements in triazines and their manufacture
AT190941B (de) * 1954-09-22 1957-07-25 Chemie Linz Ag Verfahren zur Herstellung neuer Guanylhydrazone
US2952677A (en) * 1956-10-01 1960-09-13 Ici Ltd Aminoguanadine compounds
BE663481A (uk) * 1964-05-05
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GB1223491A (en) * 1967-10-13 1971-02-24 American Home Prod Guanidines
US3637688A (en) * 1970-01-09 1972-01-25 American Home Prod 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines
IT1145308B (it) * 1979-08-16 1986-11-05 Wellcome Found Composti aromatici sostituiti

Also Published As

Publication number Publication date
NL950007I1 (nl) 1995-06-16
ZW12980A1 (en) 1982-01-06
ZA803250B (en) 1982-01-27
GEP19960470B (en) 1996-08-29
AU5890680A (en) 1980-12-04
EP0021121B1 (en) 1983-05-11
DK153787B (da) 1988-09-05
MX9202962A (es) 1992-07-01
UA5576A1 (uk) 1994-12-28
IE49823B1 (en) 1985-12-25
EP0021121A1 (en) 1981-01-07
PL124029B1 (en) 1982-12-31
ES8104993A1 (es) 1981-05-16
FI67844B (fi) 1985-02-28
EP0059987B1 (en) 1985-08-14
DK153787C (da) 1989-01-16
SU1055331A3 (ru) 1983-11-15
IL60201A (en) 1984-05-31
YU145680A (en) 1983-02-28
AU566870B2 (en) 1987-11-05
IL60201A0 (en) 1980-07-31
BG60427B2 (bg) 1995-03-31
AU530999B2 (en) 1983-08-04
CZ384891A3 (en) 1993-10-13
IT8048848A0 (it) 1980-05-30
ES491998A0 (es) 1981-05-16
NZ193890A (en) 1984-07-06
JPS6133163A (ja) 1986-02-17
JPH0144179B2 (uk) 1989-09-26
FI67844C (fi) 1985-06-10
IE801126L (en) 1980-12-01
JPH0144706B2 (uk) 1989-09-29
NL950007I2 (nl) 1997-02-03
IT1147087B (it) 1986-11-19
AR227521A1 (es) 1982-11-15
FI801758A (fi) 1980-12-02
DD151309A5 (de) 1981-10-14
CA1112643A (en) 1981-11-17
PL224633A1 (uk) 1981-02-13
AT370097B (de) 1983-02-25
HU182086B (en) 1983-12-28
US4602017A (en) 1986-07-22
US4486354A (en) 1984-12-04
ATA289680A (de) 1982-07-15
GR68380B (uk) 1981-12-28
EP0059987A1 (en) 1982-09-15
JPS5625169A (en) 1981-03-10
DK233880A (da) 1980-12-02
CS234018B2 (en) 1985-03-14

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