MY8100025A - Vinca alkaloid derivatives - Google Patents

Vinca alkaloid derivatives

Info

Publication number
MY8100025A
MY8100025A MY25/81A MY8100025A MY8100025A MY 8100025 A MY8100025 A MY 8100025A MY 25/81 A MY25/81 A MY 25/81A MY 8100025 A MY8100025 A MY 8100025A MY 8100025 A MY8100025 A MY 8100025A
Authority
MY
Malaysia
Prior art keywords
vinca alkaloid
alkaloid derivatives
derivatives
vinca
alkaloid
Prior art date
Application number
MY25/81A
Other languages
English (en)
Inventor
George Joseph Cullinan
Kdert Gerzon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MY8100025A publication Critical patent/MY8100025A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MY25/81A 1973-04-02 1981-12-30 Vinca alkaloid derivatives MY8100025A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (1)

Publication Number Publication Date
MY8100025A true MY8100025A (en) 1981-12-31

Family

ID=23363051

Family Applications (1)

Application Number Title Priority Date Filing Date
MY25/81A MY8100025A (en) 1973-04-02 1981-12-30 Vinca alkaloid derivatives

Country Status (28)

Country Link
JP (2) JPS5919117B2 (US20110009641A1-20110113-C00256.png)
AR (2) AR204004A1 (US20110009641A1-20110113-C00256.png)
AT (1) AT340605B (US20110009641A1-20110113-C00256.png)
BE (1) BE813168A (US20110009641A1-20110113-C00256.png)
BG (3) BG22831A3 (US20110009641A1-20110113-C00256.png)
CA (1) CA1042428A (US20110009641A1-20110113-C00256.png)
CH (1) CH603669A5 (US20110009641A1-20110113-C00256.png)
CS (1) CS185223B2 (US20110009641A1-20110113-C00256.png)
CY (1) CY1044A (US20110009641A1-20110113-C00256.png)
DD (1) DD113538A5 (US20110009641A1-20110113-C00256.png)
DE (1) DE2415980A1 (US20110009641A1-20110113-C00256.png)
DK (1) DK141511B (US20110009641A1-20110113-C00256.png)
ES (2) ES424882A1 (US20110009641A1-20110113-C00256.png)
FR (1) FR2223044B1 (US20110009641A1-20110113-C00256.png)
GB (1) GB1463575A (US20110009641A1-20110113-C00256.png)
HK (1) HK20180A (US20110009641A1-20110113-C00256.png)
HU (1) HU171572B (US20110009641A1-20110113-C00256.png)
IE (1) IE39071B1 (US20110009641A1-20110113-C00256.png)
IL (1) IL44415A (US20110009641A1-20110113-C00256.png)
KE (1) KE3028A (US20110009641A1-20110113-C00256.png)
MY (1) MY8100025A (US20110009641A1-20110113-C00256.png)
NL (1) NL181079C (US20110009641A1-20110113-C00256.png)
PH (1) PH13623A (US20110009641A1-20110113-C00256.png)
RO (2) RO73524B (US20110009641A1-20110113-C00256.png)
SE (1) SE416206B (US20110009641A1-20110113-C00256.png)
SU (4) SU731900A3 (US20110009641A1-20110113-C00256.png)
YU (3) YU39719B (US20110009641A1-20110113-C00256.png)
ZA (1) ZA741674B (US20110009641A1-20110113-C00256.png)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (US20110009641A1-20110113-C00256.png) * 1976-09-08 1982-07-07 Lilly Co Eli
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
LU83822A1 (fr) 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
US20080161251A1 (en) 2005-01-21 2008-07-03 Astex Therapeutics Limited Pharmaceutical Compounds
SG164368A1 (en) 2005-07-18 2010-09-29 Bipar Sciences Inc Treatment of cancer
WO2008030891A2 (en) 2006-09-05 2008-03-13 Bipar Sciences, Inc. Inhibition of fatty acid synthesis by parp inhibitors and methods of treatment thereof
CN101522609A (zh) 2006-09-05 2009-09-02 彼帕科学公司 癌症的治疗
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
KR20100102609A (ko) 2007-11-12 2010-09-24 바이파 사이언스 인코포레이티드 Parp 억제제를 단독으로 사용하거나 항종양제와 병용하여 유방암을 치료하는 방법
WO2014169697A1 (zh) * 2013-04-19 2014-10-23 暨南大学 长春碱类衍生物及其制备方法和应用
CN113456797B (zh) * 2021-06-18 2024-03-08 暨南大学 长春碱类衍生物在制备治疗骨肉瘤和/或软组织肉瘤药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
AU6671974A (en) 1975-09-18
DE2415980A1 (de) 1974-10-10
ES424882A1 (es) 1976-12-16
KE3028A (en) 1980-03-28
NL7404423A (US20110009641A1-20110113-C00256.png) 1974-10-04
RO77533A (ro) 1982-02-01
JPS6033837B2 (ja) 1985-08-05
BG21612A3 (US20110009641A1-20110113-C00256.png) 1976-07-20
YU39875B (en) 1985-04-30
CA1042428A (en) 1978-11-14
HK20180A (en) 1980-04-25
BG21235A3 (US20110009641A1-20110113-C00256.png) 1976-03-20
ES446571A1 (es) 1977-06-16
JPS59193895A (ja) 1984-11-02
NL181079B (nl) 1987-01-16
HU171572B (hu) 1978-02-28
IE39071L (en) 1974-10-02
NL181079C (nl) 1987-06-16
YU113880A (en) 1982-05-31
FR2223044B1 (US20110009641A1-20110113-C00256.png) 1978-06-30
YU81774A (en) 1982-05-31
BE813168A (fr) 1974-10-02
ZA741674B (en) 1975-10-29
SU652896A3 (ru) 1979-03-15
RO73524B (ro) 1984-11-30
BG22831A3 (US20110009641A1-20110113-C00256.png) 1977-04-20
DE2415980C2 (US20110009641A1-20110113-C00256.png) 1989-11-09
RO73524A (ro) 1984-10-31
CS185223B2 (en) 1978-09-15
SU784783A3 (ru) 1980-11-30
SE416206B (sv) 1980-12-08
YU39876B (en) 1985-04-30
AT340605B (de) 1977-12-27
GB1463575A (en) 1977-02-02
FR2223044A1 (US20110009641A1-20110113-C00256.png) 1974-10-25
AR203882A1 (es) 1975-10-31
IE39071B1 (en) 1978-08-02
CY1044A (en) 1980-08-01
YU113980A (en) 1982-05-31
YU39719B (en) 1985-04-30
IL44415A0 (en) 1974-06-30
IL44415A (en) 1978-08-31
ATA267974A (de) 1977-04-15
DK141511C (US20110009641A1-20110113-C00256.png) 1980-09-29
DD113538A5 (US20110009641A1-20110113-C00256.png) 1975-06-12
JPS5919117B2 (ja) 1984-05-02
DK141511B (da) 1980-04-08
JPS49128000A (US20110009641A1-20110113-C00256.png) 1974-12-07
CH603669A5 (US20110009641A1-20110113-C00256.png) 1978-08-31
AR204004A1 (es) 1975-11-12
SU623522A3 (ru) 1978-09-05
SU731900A3 (ru) 1980-04-30
PH13623A (en) 1980-08-07

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