MY204103A - Stable preservative-free mydriatic and anti-inflammatory solutions for injection - Google Patents

Stable preservative-free mydriatic and anti-inflammatory solutions for injection

Info

Publication number
MY204103A
MY204103A MYPI2020001054A MYPI2020001054A MY204103A MY 204103 A MY204103 A MY 204103A MY PI2020001054 A MYPI2020001054 A MY PI2020001054A MY PI2020001054 A MYPI2020001054 A MY PI2020001054A MY 204103 A MY204103 A MY 204103A
Authority
MY
Malaysia
Prior art keywords
injection
stable preservative
free
mydriatic
preservative
Prior art date
Application number
MYPI2020001054A
Other languages
English (en)
Inventor
A Demopulos Gregory
Shen Hui-Rong
E Tedford Clark
Original Assignee
Rayner Surgical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50545210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY204103(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rayner Surgical Inc filed Critical Rayner Surgical Inc
Publication of MY204103A publication Critical patent/MY204103A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/08Mydriatics or cycloplegics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
MYPI2020001054A 2012-10-24 2013-10-23 Stable preservative-free mydriatic and anti-inflammatory solutions for injection MY204103A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261718026P 2012-10-24 2012-10-24
US201261736179P 2012-12-12 2012-12-12

Publications (1)

Publication Number Publication Date
MY204103A true MY204103A (en) 2024-08-07

Family

ID=50545210

Family Applications (2)

Application Number Title Priority Date Filing Date
MYPI2020001054A MY204103A (en) 2012-10-24 2013-10-23 Stable preservative-free mydriatic and anti-inflammatory solutions for injection
MYPI2015001038A MY188474A (en) 2012-10-24 2013-10-23 Stable preservative-free mydriatic and anti-inflammatory solutions for injection

Family Applications After (1)

Application Number Title Priority Date Filing Date
MYPI2015001038A MY188474A (en) 2012-10-24 2013-10-23 Stable preservative-free mydriatic and anti-inflammatory solutions for injection

Country Status (39)

Country Link
US (6) US9066856B2 (en:Method)
EP (2) EP2911511B1 (en:Method)
JP (8) JP6017053B2 (en:Method)
KR (4) KR101808394B1 (en:Method)
CN (2) CN108721210A (en:Method)
AP (1) AP2015008459A0 (en:Method)
AR (1) AR093115A1 (en:Method)
AU (1) AU2013201465B2 (en:Method)
BR (1) BR112015009228B1 (en:Method)
CA (1) CA2887772C (en:Method)
CL (1) CL2015001078A1 (en:Method)
CR (1) CR20150233A (en:Method)
CU (1) CU20150037A7 (en:Method)
CY (1) CY1124481T1 (en:Method)
DK (1) DK2911511T3 (en:Method)
EA (1) EA033811B1 (en:Method)
ES (2) ES3040229T3 (en:Method)
GE (1) GEP20186891B (en:Method)
HR (1) HRP20210980T1 (en:Method)
HU (1) HUE055537T2 (en:Method)
IL (1) IL238439B2 (en:Method)
IN (1) IN2015DN03029A (en:Method)
LT (1) LT2911511T (en:Method)
MA (1) MA38096B1 (en:Method)
MD (1) MD20150050A2 (en:Method)
MX (2) MX382411B (en:Method)
MY (2) MY204103A (en:Method)
NZ (1) NZ628398A (en:Method)
PE (1) PE20150958A1 (en:Method)
PH (1) PH12015500850B1 (en:Method)
PL (1) PL2911511T3 (en:Method)
PT (1) PT2911511T (en:Method)
RS (1) RS62188B1 (en:Method)
SG (1) SG11201502602WA (en:Method)
SI (1) SI2911511T1 (en:Method)
SM (1) SMT202100393T1 (en:Method)
UA (1) UA114650C2 (en:Method)
WO (1) WO2014066485A1 (en:Method)
ZA (1) ZA201502684B (en:Method)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103143022A (zh) 2002-07-30 2013-06-12 奥默罗斯公司 眼科冲洗液及方法
AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Intraocular Lenses Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
MX2016004257A (es) 2013-10-03 2016-08-17 Imprimis Pharmaceuticals Inc Composiciones oftalmicas basadas en epinefrina para la administracion intraocular y metodos para su frabricacion.
US20210346318A1 (en) * 2013-10-03 2021-11-11 Harrow Ip, Llc Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof
TWI705812B (zh) 2014-12-01 2020-10-01 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
CN104856990A (zh) * 2015-05-07 2015-08-26 武汉武药科技有限公司 去氧肾上腺素酮咯酸溶液及制备方法
US11213480B1 (en) 2015-08-06 2022-01-04 Hikma Pharmaceuticals International Limited Phenylephrine hydrochloride ready-to-use solution
USD831868S1 (en) 2015-09-17 2018-10-23 Lume Cube, Inc. Compact external light
US10704745B2 (en) 2015-10-13 2020-07-07 Lume Cube, Inc. Mobile light source
KR20190035927A (ko) 2016-08-25 2019-04-03 임프리미스 파마슈티컬스, 인크. 안구 내 투여를 위한 에피네프린-기반 안과용 조성물 및 이의 제조방법
US20180318319A1 (en) * 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
JP7078843B2 (ja) * 2018-03-26 2022-06-01 サミー株式会社 遊技機
WO2020087021A1 (en) * 2018-10-26 2020-04-30 Ocuphire Pharma, Inc. Methods and compositions for treatment of presbyopia, mydriasis, and other ocular disorders
US11071724B2 (en) 2019-05-17 2021-07-27 Ocular Science, Inc. Compositions and methods for treating presbyopia
DE102019125430B3 (de) * 2019-09-20 2020-11-19 Carl Zeiss Meditec Ag Steuerungsvorrichtung für ein ophthalmochirurgisches System, ophthalmochirurgisches System sowie Computerprogrammprodukt
KR102749980B1 (ko) 2020-01-02 2025-01-03 삼성전자주식회사 에어 스페이서를 가지는 반도체 소자
US20210228507A1 (en) * 2020-01-22 2021-07-29 Nevakar Inc. Phenylephrine Hydrochloride Compositions and Containers
WO2022132567A1 (en) * 2020-12-17 2022-06-23 Harrow Ip, Llc Mydriatic compositions and methods for fabricating thereof
CN115368310B (zh) 2021-05-18 2025-06-27 奥库菲尔医药公司 合成甲磺酸酚妥拉明的方法
US11883382B2 (en) 2021-07-23 2024-01-30 Somerset Therapeutics, Llc Buffer-free ophthalmological compositions of ketorolac and phenylephrine and applications thereof
US12029729B2 (en) 2021-07-23 2024-07-09 Somerset Therapeutics, Llc Chelated, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof
EP4604924A1 (en) * 2022-10-19 2025-08-27 Fresenius Kabi Austria GmbH Phenylephrine liquid formulations
CN115950992B (zh) * 2023-03-15 2023-06-09 苏州朗易生物医药研究有限公司 一种去氧肾上腺素酮咯酸溶液中有关物质的检测方法及其应用
WO2025165753A1 (en) * 2024-01-31 2025-08-07 Hikma Pharmaceuticals Usa Inc. Pharmaceutical formulations of phenylephrine and process of making the same

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4402949A (en) 1979-11-12 1983-09-06 Sandoz Ltd. Stable solutions of hydrogenated ergotalkaloids
US4550022A (en) 1981-10-05 1985-10-29 Alcon Laboratories, Inc. Tissue irrigating solution
JPS58126810A (ja) 1981-12-24 1983-07-28 Kaken Pharmaceut Co Ltd 抗炎症眼科用液剤およびその製法
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
JPS6017053U (ja) 1983-07-11 1985-02-05 住友電気工業株式会社 伝送エラ−検出器
WO1987007141A1 (en) 1986-05-23 1987-12-03 New England Medical Center Hospitals, Inc. Method for treating glaucoma
US5212196A (en) 1986-10-21 1993-05-18 Alcon Laboratories, Inc. Control of post-surgical intraocular pressure using clonidine derivatives
US4938970A (en) 1987-02-06 1990-07-03 Hustead Robert E Painless electrolyte solutions
US5110493A (en) 1987-09-11 1992-05-05 Syntex (U.S.A.) Inc. Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
US4876250A (en) 1988-10-31 1989-10-24 Alcon Laboratories, Inc. Methods for controlling ocular hypertension with angiostatic steroids
DE3833893A1 (de) 1988-10-05 1990-04-12 Bayer Ag Verwendung von basischen nitro-phenyl-dihydropyridin-amiden als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung ueber neue zwischenprodukte
US5036046A (en) 1988-10-12 1991-07-30 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
US5051443A (en) 1988-10-12 1991-09-24 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
US5371078A (en) 1988-10-31 1994-12-06 Alcon Laboratories, Inc. Angiostatic steroids and methods and compositions for controlling ocular hypertension
US5116868A (en) 1989-05-03 1992-05-26 The Johns Hopkins University Effective ophthalmic irrigation solution
CA2065375A1 (en) 1989-08-21 1991-02-22 Richard J. Sharpe Method and composition for the treatment of cutaneous, ocular, and mucosal hypersensitivity, inflammation, and hyperproliferative conditions using topical preparations of serotonin antagonists
US5679650A (en) * 1993-11-24 1997-10-21 Fukunaga; Atsuo F. Pharmaceutical compositions including mixtures of an adenosine compound and a catecholamine
JPH05506035A (ja) 1990-09-07 1993-09-02 ユニベルシダド、ド、アリカンテ 眼痛治療用組成物
US5318780A (en) 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
IT1252692B (it) 1991-11-27 1995-06-23 Zambon Spa Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi
EP0619739A1 (en) 1992-10-21 1994-10-19 Alcon Laboratories, Inc. Composition for irrigating intraocular tissues and maintaining mydriasis during intraocular surgery
US6117907A (en) 1993-04-14 2000-09-12 Sher; Neal A. Topical treatment of ocular pain after corneal surgery
JPH08503968A (ja) 1993-09-29 1996-04-30 アルコン ラボラトリーズ,インコーポレイテッド 増殖因子と代謝拮抗物質を含有する組成物
WO1995009004A1 (en) 1993-09-29 1995-04-06 Alcon Laboratories, Inc. Compositions containing growth factors and antiplastic agents
US5624893A (en) 1993-10-14 1997-04-29 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
WO1995016435A2 (en) 1993-12-17 1995-06-22 Alcon Laboratories, Inc. Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent
US6350781B1 (en) 1994-01-14 2002-02-26 Lee Shahinia, Jr. Method and analgesic preparations for sustained and extended corneal analgesia with subanesthetic concentrations of lidocaine
WO1995034298A1 (en) 1994-06-10 1995-12-21 Telor Ophthalmic Pharmaceuticals, Inc. Inhibition of intraoperative miosis/production of mydriasis by local anesthetics
US5523316A (en) 1994-06-23 1996-06-04 Alcon Laboratories, Inc. Intraocular irrigating solution containing agent for controlling IOP
US7091181B2 (en) 1994-12-12 2006-08-15 Omeros Corporation Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
WO2000023061A2 (en) 1998-10-21 2000-04-27 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
US6492332B1 (en) 1995-12-12 2002-12-10 Omeros Corporation Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
AU4467396A (en) 1994-12-12 1996-07-10 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain, inflammation and spasm
WO2000025745A2 (en) 1998-11-05 2000-05-11 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
WO2000023062A2 (en) 1998-10-20 2000-04-27 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
KR100517210B1 (ko) 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
DE69534341T2 (de) 1994-12-12 2006-05-24 Omeros Corp., Seattle Bespüllungslösung und deren verwendung zur perioperativen hemmung von schmerzen, entzündungen und spasmen an einer wunde
US5972326A (en) 1995-04-18 1999-10-26 Galin; Miles A. Controlled release of pharmaceuticals in the anterior chamber of the eye
US5612027A (en) 1995-04-18 1997-03-18 Galin; Miles A. Controlled release of miotic and mydriatic drugs in the anterior chamber
US5767105A (en) 1995-05-03 1998-06-16 Peyman; Gholam A. Ocular solution
US5798356A (en) 1995-08-07 1998-08-25 Alcon Laboratories, Inc. Angiostatic compounds
US5849761A (en) 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6413961B1 (en) 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
US6280745B1 (en) 1997-12-23 2001-08-28 Alliance Pharmaceutical Corp. Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions
WO1998004171A1 (en) 1996-07-26 1998-02-05 Schein Dental Equipment Co. Armrest mechanism for dental chairs
GB9704352D0 (en) 1997-03-03 1997-04-23 Chiroscience Ltd Levobupivacaine and its use
WO1998043619A2 (en) 1997-04-02 1998-10-08 The Regents Of The University Of California Method of local anesthesia
US5811446A (en) 1997-04-18 1998-09-22 Cytos Pharmaceuticals Llc Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor
US6034256A (en) 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
US6495598B1 (en) 1997-04-22 2002-12-17 Ophtecs Corporation Perfusate preparation for ophthalmic operation
EP0903151A1 (en) 1997-09-22 1999-03-24 ASTA Medica Aktiengesellschaft Use of combinations comprising non-sedating antihistamines and alpha-adrenergic drugs for the topical treatment of rhinitis/conjunctivitis and cold, cold-like and/or flu symptoms
DE69928806T2 (de) 1998-07-01 2006-07-20 Warner-Lambert Co. Llc (-)-pseudoephedrin als sympathomimetisches arzneimittel
DK1037627T3 (da) 1998-07-14 2001-10-01 Alcon Lab Inc Anvendelse af 11-(3-dimethylamino-propyliden)-6, 11-dihydrodibenz[b,e]oxepin-2-eddikesyre og af farmaceutisk acceptable salte deraf til fremstillingen af et lægemiddel til behandlingen af non-allergiske...
US6262066B1 (en) 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
FR2782721B1 (fr) 1998-09-01 2000-11-03 Inst Nat Sante Rech Med Nouveaux composes phosphohalohydrines, procede de fabrication et applications
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US7973068B2 (en) 1998-10-20 2011-07-05 Omeros Corporation Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation
US20030087962A1 (en) 1998-10-20 2003-05-08 Omeros Corporation Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation
ES2239466T3 (es) 1998-10-20 2005-09-16 Omeros Corporation Solucion de irrigacion y metodo de inhibicion del dolor y de la inflamacion.
AU1127700A (en) 1998-10-20 2000-05-08 Omeros Medical Systems, Inc. Irrigation solution containing mapk inhibitors and their use for treating pain and inflammation
AU3119100A (en) 1998-12-17 2000-07-03 Alcon Laboratories, Inc. Methods for the prevention and treatment of post-surgical complications
MXPA01008729A (es) * 1999-03-02 2003-06-24 Vitreo Retinal Technologies In Agentes para administracion intravitrea para tratar o prevenir desordenes del ojo.
HK1047216A1 (zh) 1999-05-14 2003-02-14 加利福尼亚大学董事会 对炎症介导感染的抗炎症治疗
AU5286901A (en) 1999-10-22 2001-06-18 Transdermatech, Inc. Topical anesthetic formulation
US6218428B1 (en) 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
JP2004512260A (ja) 2000-04-28 2004-04-22 メモリアル スローン−ケッタリング キャンサー センター 局所麻酔/オピオイド製剤およびその使用方法
PE20020146A1 (es) 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
CA2414674A1 (en) 2000-07-13 2002-01-24 Pharmacia Corporation Use of cox-2 inhibitors in the treatment and prevention of ocular cox-2 mediated disorders
EP2153819B1 (en) 2000-07-14 2012-09-05 Allergan, Inc. Use of a solubility enhancing component in an aqueous composition comprising brimonidine tartrate
MXPA03000729A (es) 2000-07-28 2004-11-01 Inspire Pharmaceuticals Inc Metodo para reducir la presion intraocular utilizando derivados de indol.
JP2002161032A (ja) 2000-09-14 2002-06-04 Taisho Pharmaceut Co Ltd 粘膜適用組成物
CN1390124A (zh) 2000-09-20 2003-01-08 永光制药有限公司 近视眼的预防、治疗药
US20020183279A1 (en) 2001-04-18 2002-12-05 Koichiro Tanaka Pharmaceutical composition containing viscoelastic substance and medication
US20020198209A1 (en) 2001-05-03 2002-12-26 Allergan Sales Inc. Compositions having enhanced pharmacokinetic characteristics
US20030191187A1 (en) * 2002-04-01 2003-10-09 Lee Fang Yu Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same
CN103143022A (zh) 2002-07-30 2013-06-12 奥默罗斯公司 眼科冲洗液及方法
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
CA2591706A1 (en) 2004-12-22 2006-06-29 Schering Corporation Pharmaceutical formulations
SG161208A1 (en) 2004-12-23 2010-05-27 Roxro Pharma Inc Therapeutic compositions for intranasal administration of ketorolac
FR2882930B1 (fr) 2005-03-09 2009-03-27 Walid Katib Nouvelles compositions ophtalmologiques et leur mode d'utilisation
DOP2007000055A (es) * 2006-04-10 2007-10-31 Senosiain S A De C V Lab Composición farmaceutica que comprende un analgésico y vitaminas
CA2697160A1 (en) 2007-08-21 2009-02-26 Harbor Biosciences, Inc. Stabilized therapeutic compositions and formulations
CA2705050A1 (en) 2007-11-08 2009-05-14 Aciex Therapeutics, Inc. Compositions for the treatment and prevention of eyelid swelling
WO2009074853A2 (en) 2007-12-10 2009-06-18 Promed Research Centre Ophthalmic composition comprising phenylephrine
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
US7842714B2 (en) 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
EP2403532A4 (en) * 2009-03-06 2012-12-05 Medimmune Llc HUMANIZED ANTI-CD19 ANTIBODY FORMULATIONS
US8277781B2 (en) 2009-03-13 2012-10-02 Luitpold Pharmaceuticals, Inc. Device for intranasal administration
US20100311688A1 (en) * 2009-06-05 2010-12-09 Aciex Therapeutics, Inc. Ophthalmic formulations, methods of manufacture, and methods of using same
JP2012528889A (ja) * 2009-06-05 2012-11-15 アーシエックス セラピューティックス, インコーポレイテッド フルチカゾンの眼科処方物および使用方法
US8680510B2 (en) 2010-06-28 2014-03-25 International Business Machines Corporation Method of forming compound semiconductor
PL2598119T3 (pl) 2010-07-29 2019-03-29 Allergan, Inc. Niezawierające konserwantów roztwory brymonidyny i timololu
AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Intraocular Lenses Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI705812B (zh) 2014-12-01 2020-10-01 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液

Also Published As

Publication number Publication date
WO2014066485A1 (en) 2014-05-01
MD20150050A2 (ro) 2015-09-30
HUE055537T2 (hu) 2021-12-28
KR20150068990A (ko) 2015-06-22
EP3909572C0 (en) 2025-08-06
JP6282699B2 (ja) 2018-02-21
AP2015008459A0 (en) 2015-05-31
HK1213434A1 (en) 2016-07-08
LT2911511T (lt) 2021-07-26
RS62188B1 (sr) 2021-08-31
US20150342928A1 (en) 2015-12-03
UA114650C2 (uk) 2017-07-10
US20180085349A1 (en) 2018-03-29
US20220175726A1 (en) 2022-06-09
JP2020147606A (ja) 2020-09-17
KR101808394B1 (ko) 2017-12-12
JP6017053B2 (ja) 2016-10-26
US9066856B2 (en) 2015-06-30
US12133842B2 (en) 2024-11-05
MX382411B (es) 2025-03-13
EP2911511A1 (en) 2015-09-02
AU2013201465B2 (en) 2016-03-03
CY1124481T1 (el) 2022-07-22
JP2017014294A (ja) 2017-01-19
CL2015001078A1 (es) 2015-09-04
EP2911511A4 (en) 2015-12-16
JP2019081798A (ja) 2019-05-30
EP3909572B1 (en) 2025-08-06
ZA201502684B (en) 2016-01-27
KR20210018954A (ko) 2021-02-18
ES3040229T3 (en) 2025-10-29
PL2911511T3 (pl) 2021-11-15
SI2911511T1 (sl) 2021-09-30
PH12015500850A1 (en) 2015-06-22
CA2887772A1 (en) 2014-05-01
MX2020012591A (es) 2022-11-04
US20140235691A1 (en) 2014-08-21
CU20150037A7 (es) 2015-08-27
CN108721210A (zh) 2018-11-02
US20250032452A1 (en) 2025-01-30
BR112015009228A2 (pt) 2017-07-04
PT2911511T (pt) 2021-07-06
PE20150958A1 (es) 2015-07-09
JP2018058905A (ja) 2018-04-12
JP2016196511A (ja) 2016-11-24
SMT202100393T1 (it) 2021-09-14
MY188474A (en) 2021-12-13
NZ628398A (en) 2016-03-31
CR20150233A (es) 2015-08-14
JP2015535250A (ja) 2015-12-10
US9855246B2 (en) 2018-01-02
JP2023041804A (ja) 2023-03-24
US9486406B2 (en) 2016-11-08
DK2911511T3 (en) 2021-06-28
GEP20186891B (en) 2018-09-10
EA033811B1 (ru) 2019-11-27
KR102211784B1 (ko) 2021-02-04
MX2015005089A (es) 2015-07-17
MA38096A1 (fr) 2016-10-31
ES2875432T3 (es) 2021-11-10
KR20170128640A (ko) 2017-11-22
AU2013201465A1 (en) 2014-05-08
SG11201502602WA (en) 2015-05-28
PH12015500850B1 (en) 2017-11-17
HRP20210980T1 (hr) 2021-09-17
IN2015DN03029A (en:Method) 2015-10-02
KR102496463B1 (ko) 2023-02-06
CN104822265A (zh) 2015-08-05
KR20200000487A (ko) 2020-01-02
BR112015009228A8 (pt) 2022-07-12
AR093115A1 (es) 2015-05-20
US20170196838A1 (en) 2017-07-13
IL238439A0 (en) 2015-06-30
MA38096B1 (fr) 2019-12-31
IL238439B1 (en) 2023-07-01
EP3909572A1 (en) 2021-11-17
IL238439B2 (en) 2023-11-01
BR112015009228B1 (pt) 2022-07-19
EP2911511B1 (en) 2021-04-14
EA201590807A1 (ru) 2015-11-30
JP2025019330A (ja) 2025-02-06
CA2887772C (en) 2017-02-21

Similar Documents

Publication Publication Date Title
PH12015500850A1 (en) Stable preservative-free mydriatic and anti-inflammatory solutions for injection
NZ702663A (en) Nuclear transport modulators and uses thereof
BR112014032990A2 (pt) seringa
PH12014501967B1 (en) Benzodioxanes in combination with other actives for inhibiting leukotriene production
MY168212A (en) A new therapeutical composition containing apomorphine as active ingredient
PH12016500924A1 (en) Anti-cancer agents and preparation thereof
CO6920289A2 (es) Composición farmacéutica oftalmológica tópica que contiene regorafenib.
MX347373B (es) Soluciones anti-inflamatorias estables para inyección.
EA201491300A1 (ru) Композиция для назального применения с улучшенной стабильностью
TR201100148A2 (tr) Stabil akarboz förmülasyonları.
MX2020012953A (es) Usos del extracto de bacopa monnieri.
WO2014104989A8 (en) Pharmaceutical compositions comprising aripiprazole
IN2013CH04314A (en:Method)
IN2015DN00962A (en:Method)
PL399298A1 (pl) Kompozycja farmaceutyczna do stosowania miejscowego zawierajaca acyklowir oraz sposób jej wytwarzania
UA105703C2 (uk) 7-бром-5-феніл-3-ариламіно-1,2-дигідро-3н-1,4-бенздіазепін-2-они як анальгетичні агенти