PE20150958A1 - Soluciones midriaticas y antiinflamatorias inyectables, estables y libres de conservantes - Google Patents

Soluciones midriaticas y antiinflamatorias inyectables, estables y libres de conservantes

Info

Publication number
PE20150958A1
PE20150958A1 PE2015000544A PE2015000544A PE20150958A1 PE 20150958 A1 PE20150958 A1 PE 20150958A1 PE 2015000544 A PE2015000544 A PE 2015000544A PE 2015000544 A PE2015000544 A PE 2015000544A PE 20150958 A1 PE20150958 A1 PE 20150958A1
Authority
PE
Peru
Prior art keywords
stable
myriatic
injectable
preservative free
solutions
Prior art date
Application number
PE2015000544A
Other languages
English (en)
Inventor
Gregory A Demopulos
Hui-Rong Shen
Clark E Tedford
Original Assignee
Omeros Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50545210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20150958(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Omeros Corp filed Critical Omeros Corp
Publication of PE20150958A1 publication Critical patent/PE20150958A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/08—Mydriatics or cycloplegics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Abstract

La invencion se refiere a formulaciones inyectables liquidas estables que comprenden fenilefrina y ketorolaco, libres de conservantes y de antioxidantes. Las formulaciones de la invencion pueden inyectarse en soluciones oftalmicas de irrigacion ocular, con el proposito de irrigar los tejidos del ojo durante una cirugia
PE2015000544A 2012-10-24 2013-10-23 Soluciones midriaticas y antiinflamatorias inyectables, estables y libres de conservantes PE20150958A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261718026P 2012-10-24 2012-10-24
US201261736179P 2012-12-12 2012-12-12

Publications (1)

Publication Number Publication Date
PE20150958A1 true PE20150958A1 (es) 2015-07-09

Family

ID=50545210

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2015000544A PE20150958A1 (es) 2012-10-24 2013-10-23 Soluciones midriaticas y antiinflamatorias inyectables, estables y libres de conservantes

Country Status (39)

Country Link
US (5) US9066856B2 (es)
EP (2) EP3909572A1 (es)
JP (7) JP6017053B2 (es)
KR (4) KR20170128640A (es)
CN (2) CN104822265A (es)
AP (1) AP2015008459A0 (es)
AR (1) AR093115A1 (es)
AU (1) AU2013201465B2 (es)
BR (1) BR112015009228B1 (es)
CA (1) CA2887772C (es)
CL (1) CL2015001078A1 (es)
CR (1) CR20150233A (es)
CU (1) CU20150037A7 (es)
CY (1) CY1124481T1 (es)
DK (1) DK2911511T3 (es)
EA (1) EA033811B1 (es)
ES (1) ES2875432T3 (es)
GE (1) GEP20186891B (es)
HK (1) HK1213434A1 (es)
HR (1) HRP20210980T1 (es)
HU (1) HUE055537T2 (es)
IL (1) IL238439B2 (es)
IN (1) IN2015DN03029A (es)
LT (1) LT2911511T (es)
MA (1) MA38096B1 (es)
MD (1) MD20150050A2 (es)
MX (2) MX2020012591A (es)
MY (1) MY188474A (es)
NZ (1) NZ628398A (es)
PE (1) PE20150958A1 (es)
PH (1) PH12015500850B1 (es)
PL (1) PL2911511T3 (es)
PT (1) PT2911511T (es)
RS (1) RS62188B1 (es)
SG (1) SG11201502602WA (es)
SI (1) SI2911511T1 (es)
UA (1) UA114650C2 (es)
WO (1) WO2014066485A1 (es)
ZA (1) ZA201502684B (es)

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US10993921B2 (en) * 2013-10-03 2021-05-04 Harrow Ip, Llc Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof
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CN104856990A (zh) * 2015-05-07 2015-08-26 武汉武药科技有限公司 去氧肾上腺素酮咯酸溶液及制备方法
US11213480B1 (en) * 2015-08-06 2022-01-04 Hikma Pharmaceuticals International Limited Phenylephrine hydrochloride ready-to-use solution
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CA3034640A1 (en) 2016-08-25 2018-03-01 Imprimis Pharmaceuticals, Inc. Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof
US20180318319A1 (en) * 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
JP7078843B2 (ja) * 2018-03-26 2022-06-01 サミー株式会社 遊技機
BR112021007725A2 (pt) * 2018-10-26 2021-07-27 Ocuphire Pharma, Inc. métodos e composições para tratamento de presbiopia, midríase e outros distúrbios oculares
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KR20210087352A (ko) 2020-01-02 2021-07-12 삼성전자주식회사 에어 스페이서를 가지는 반도체 소자
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CN115368310A (zh) 2021-05-18 2022-11-22 奥库菲尔医药公司 合成甲磺酸酚妥拉明的方法
US11793789B2 (en) 2021-07-23 2023-10-24 Somerset Therapeutics, Llc Treatment of ophthalmological conditions using buffer-free ophthalmological compositions of ketorolac and phenylephrine
CN115950992B (zh) * 2023-03-15 2023-06-09 苏州朗易生物医药研究有限公司 一种去氧肾上腺素酮咯酸溶液中有关物质的检测方法及其应用

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Also Published As

Publication number Publication date
CL2015001078A1 (es) 2015-09-04
AR093115A1 (es) 2015-05-20
PT2911511T (pt) 2021-07-06
BR112015009228A2 (pt) 2017-07-04
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