HUE040283T2 - Brimonidin és timolol tartalmú, tartósítószer-mentes oldatok - Google Patents
Brimonidin és timolol tartalmú, tartósítószer-mentes oldatokInfo
- Publication number
- HUE040283T2 HUE040283T2 HUE11745861A HUE11745861A HUE040283T2 HU E040283 T2 HUE040283 T2 HU E040283T2 HU E11745861 A HUE11745861 A HU E11745861A HU E11745861 A HUE11745861 A HU E11745861A HU E040283 T2 HUE040283 T2 HU E040283T2
- Authority
- HU
- Hungary
- Prior art keywords
- preservative free
- brimonidine
- timolol
- solutions
- timolol solutions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36868110P | 2010-07-29 | 2010-07-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE040283T2 true HUE040283T2 (hu) | 2019-02-28 |
Family
ID=44504227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE11745861A HUE040283T2 (hu) | 2010-07-29 | 2011-07-28 | Brimonidin és timolol tartalmú, tartósítószer-mentes oldatok |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10213431B2 (hu) |
| EP (2) | EP2598119B1 (hu) |
| AU (1) | AU2011282683B2 (hu) |
| CA (1) | CA2807084C (hu) |
| DK (1) | DK2598119T3 (hu) |
| ES (1) | ES2709180T3 (hu) |
| HU (1) | HUE040283T2 (hu) |
| PL (1) | PL2598119T3 (hu) |
| PT (1) | PT2598119T (hu) |
| SI (1) | SI2598119T1 (hu) |
| TR (1) | TR201818754T4 (hu) |
| WO (1) | WO2012016000A2 (hu) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013201465B2 (en) | 2012-10-24 | 2016-03-03 | Rayner Surgical (Ireland) Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
| GR1008330B (el) * | 2013-10-17 | 2014-10-20 | "Φαρματεν Α.Β.Ε.Ε.", | Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χορηγηση εχoν βελτιωμενες φυσικες ιδιοτητες και ογκο σταγονας |
| GR1008483B (el) * | 2013-12-23 | 2015-05-12 | Rafarm Α.Ε.Β.Ε., | Οφθαλμικη φαρμακευτικη συνθεση και μεθοδος για την παρασκευη αυτης |
| TWI705812B (zh) | 2014-12-01 | 2020-10-01 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
| KR20170129823A (ko) * | 2015-03-19 | 2017-11-27 | 알러간, 인코포레이티드 | 브리모니딘 및 티몰롤의 고정된 용량 조합 |
| KR20180014768A (ko) * | 2015-06-05 | 2018-02-09 | 산텐 세이야꾸 가부시키가이샤 | 소프트 콘택트렌즈가 착용된 드라이아이 환자의 눈에 점안되도록 이용되는 것을 특징으로 하는 드라이아이 치료제 |
| EP3474831A1 (en) * | 2016-06-23 | 2019-05-01 | Corium International, Inc. | Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent |
| KR20230109782A (ko) | 2016-07-27 | 2023-07-20 | 코리움, 엘엘씨 | 아민 약물의 나트륨 바이카보네이트 제자리 전환 구동된경피성 전달 |
| US11173132B2 (en) | 2017-12-20 | 2021-11-16 | Corium, Inc. | Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point |
| GR1010024B (el) * | 2020-05-06 | 2021-06-01 | Φαρματεν Α.Β.Ε.Ε. | Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χορηγηση που περιλαμβανει βριμονιδινη |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795970A (fr) | 1972-02-29 | 1973-08-27 | Pfizer | Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant |
| US4195085A (en) | 1975-09-26 | 1980-03-25 | Merck & Co., Inc. | Compositions and methods for treating glaucoma by the topical administration of t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy-2-phopanol hydrogen maleate |
| CA1334168C (en) | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
| US5021416A (en) | 1989-10-31 | 1991-06-04 | Allergan, Inc. | Method for using (2-imidazolin-2-ylamino) quinoxalines to reduce or maintain intraocular pressure |
| US5688819A (en) | 1992-09-21 | 1997-11-18 | Allergan | Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US7030149B2 (en) | 2002-04-19 | 2006-04-18 | Allergan, Inc. | Combination of brimonidine timolol for topical ophthalmic use |
| CA2536061A1 (en) * | 2003-08-22 | 2005-03-17 | Edward J. Ellis | Polymeric systems for controlled drug therapy |
| WO2008024846A2 (en) | 2006-08-25 | 2008-02-28 | Allergan, Inc. | Brimonidine and timolol compositions |
| MX2007010025A (es) * | 2007-08-17 | 2009-02-25 | Arturo Jimenez Bayardo | Composición farmacéutica para tratamiento de hipertensión ocular. |
| WO2011087790A1 (en) | 2009-12-22 | 2011-07-21 | Allergan, Inc. | Triple combination for lowering intraocular pres sure |
-
2011
- 2011-07-28 US US13/812,599 patent/US10213431B2/en not_active Expired - Fee Related
- 2011-07-28 EP EP11745861.2A patent/EP2598119B1/en not_active Revoked
- 2011-07-28 HU HUE11745861A patent/HUE040283T2/hu unknown
- 2011-07-28 TR TR2018/18754T patent/TR201818754T4/tr unknown
- 2011-07-28 PL PL11745861T patent/PL2598119T3/pl unknown
- 2011-07-28 WO PCT/US2011/045656 patent/WO2012016000A2/en active Application Filing
- 2011-07-28 EP EP18194001.6A patent/EP3434257A1/en not_active Withdrawn
- 2011-07-28 PT PT11745861T patent/PT2598119T/pt unknown
- 2011-07-28 DK DK11745861.2T patent/DK2598119T3/en active
- 2011-07-28 SI SI201131629T patent/SI2598119T1/sl unknown
- 2011-07-28 AU AU2011282683A patent/AU2011282683B2/en not_active Ceased
- 2011-07-28 ES ES11745861T patent/ES2709180T3/es active Active
- 2011-07-28 CA CA2807084A patent/CA2807084C/en active Active
-
2019
- 2019-01-10 US US16/245,026 patent/US10792288B2/en active Active
-
2020
- 2020-09-09 US US17/015,615 patent/US20210228587A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012016000A2 (en) | 2012-02-02 |
| US20190307759A1 (en) | 2019-10-10 |
| EP2598119A2 (en) | 2013-06-05 |
| AU2011282683B2 (en) | 2016-12-22 |
| EP3434257A1 (en) | 2019-01-30 |
| PL2598119T3 (pl) | 2019-03-29 |
| SI2598119T1 (sl) | 2019-02-28 |
| ES2709180T3 (es) | 2019-04-15 |
| US10792288B2 (en) | 2020-10-06 |
| PT2598119T (pt) | 2018-12-17 |
| CA2807084A1 (en) | 2012-02-02 |
| WO2012016000A3 (en) | 2012-03-15 |
| EP2598119B1 (en) | 2018-09-19 |
| US10213431B2 (en) | 2019-02-26 |
| US20210228587A1 (en) | 2021-07-29 |
| TR201818754T4 (tr) | 2019-01-21 |
| CA2807084C (en) | 2018-05-22 |
| AU2011282683A1 (en) | 2013-03-07 |
| US20140148456A1 (en) | 2014-05-29 |
| DK2598119T3 (en) | 2019-01-07 |
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