SI3431074T1 - Raztopine bimatoprosta in timolola brez konzervansov - Google Patents

Raztopine bimatoprosta in timolola brez konzervansov

Info

Publication number
SI3431074T1
SI3431074T1 SI201132054T SI201132054T SI3431074T1 SI 3431074 T1 SI3431074 T1 SI 3431074T1 SI 201132054 T SI201132054 T SI 201132054T SI 201132054 T SI201132054 T SI 201132054T SI 3431074 T1 SI3431074 T1 SI 3431074T1
Authority
SI
Slovenia
Prior art keywords
preservative free
free bimatoprost
timolol
solutions
timolol solutions
Prior art date
Application number
SI201132054T
Other languages
English (en)
Inventor
Sukhon Likitlersuang
Ajay P. Parashar
Chetan P. Pujara
William F. Kelly
Original Assignee
Allergan, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44504226&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI3431074(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan, Inc. filed Critical Allergan, Inc.
Publication of SI3431074T1 publication Critical patent/SI3431074T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI201132054T 2010-07-29 2011-07-28 Raztopine bimatoprosta in timolola brez konzervansov SI3431074T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36868510P 2010-07-29 2010-07-29
EP18182158.8A EP3431074B1 (en) 2010-07-29 2011-07-28 Preservative free bimatoprost and timolol solutions

Publications (1)

Publication Number Publication Date
SI3431074T1 true SI3431074T1 (sl) 2022-07-29

Family

ID=44504226

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201132054T SI3431074T1 (sl) 2010-07-29 2011-07-28 Raztopine bimatoprosta in timolola brez konzervansov
SI201131614T SI2598118T1 (sl) 2010-07-29 2011-07-28 Raztopine z bimatoprostom in timololom brez konzervansov

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI201131614T SI2598118T1 (sl) 2010-07-29 2011-07-28 Raztopine z bimatoprostom in timololom brez konzervansov

Country Status (16)

Country Link
US (2) US9078854B2 (sl)
EP (2) EP2598118B1 (sl)
JP (1) JP6014033B2 (sl)
KR (1) KR101820184B1 (sl)
CN (1) CN103068364B (sl)
AU (1) AU2011282681B2 (sl)
CA (1) CA2807081C (sl)
DK (1) DK2598118T3 (sl)
ES (2) ES2708451T3 (sl)
HR (1) HRP20220626T1 (sl)
HU (2) HUE059325T2 (sl)
PL (1) PL2598118T3 (sl)
PT (2) PT2598118T (sl)
RU (1) RU2624534C2 (sl)
SI (2) SI3431074T1 (sl)
WO (1) WO2012015998A2 (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3431074T1 (sl) 2010-07-29 2022-07-29 Allergan, Inc. Raztopine bimatoprosta in timolola brez konzervansov
US9061034B2 (en) * 2010-07-29 2015-06-23 Allergan, Inc. Preservative free bimatoprost and timolol solutions
US9248135B2 (en) 2012-04-24 2016-02-02 Allergan, Inc. Prostaglandin and vasoconstrictor pharmaceutical compositions and methods of use
EP3057575B1 (en) 2013-10-15 2021-09-08 Pharmathen S.A. Preservative free pharmaceutical compositions for ophthalmic administration
GR1008483B (el) * 2013-12-23 2015-05-12 Rafarm Α.Ε.Β.Ε., Οφθαλμικη φαρμακευτικη συνθεση και μεθοδος για την παρασκευη αυτης
GR1009006B (el) * 2016-04-01 2017-04-04 Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χρηση περιεχον βιματοπροστη και τιμολολη
PL431139A1 (pl) * 2019-09-13 2021-03-22 Warszawskie Zakłady Farmaceutyczne Polfa Spółka Akcyjna Kompozycja farmaceutyczna bimatoprostu i tymololu
US11786538B2 (en) 2019-12-11 2023-10-17 Somerset Therapeutics, Llc Low benzalkonium chloride bimatoprost ophthalmic compositions with effective penetration and preservation properties
KR20220100194A (ko) 2021-01-08 2022-07-15 이동혁 식품 방부제 스티커
US20230293541A1 (en) 2022-03-21 2023-09-21 Somerset Therapeutics, Llc Methods of treating ophthalmic conditions with enhanced penetration compositions of bimatoprost and timolol

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US368685A (en) 1887-08-23 peahae
US4599353A (en) 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
DE3220156C2 (de) 1982-05-28 1990-01-25 Heida Houston Tex. Thurlow Mit Metallgriffen, insbesondere Edelstahlgriffen, versehenes Koch- und Bratgeschirr mit Deckel
CH665587A5 (de) 1984-11-07 1988-05-31 Wiederkehr Hans Schleifkopf.
EP0286903B2 (en) 1987-04-03 2000-03-29 The Trustees Of Columbia University In The City Of New York Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure
JP2721414B2 (ja) 1988-09-06 1998-03-04 フアーマシア・アンド・アツプジヨン・アー・ベー 縁内障または眼圧亢進の治療のためのプロスタグランジン誘導体
US5034413A (en) 1989-07-27 1991-07-23 Allergan, Inc. Intraocular pressure reducing 9,11-diacyl prostaglandins
US5028624A (en) 1989-07-27 1991-07-02 Allergan, Inc. Intraocular pressure reducing 9,15-diacyl prostaglandins
US4994274A (en) 1989-07-27 1991-02-19 Allergan, Inc. Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using
EP0458590B1 (en) 1990-05-22 1996-01-10 R-Tech Ueno Ltd. Treatment of ocular hypertention with a synergistic combination
SK282039B6 (sk) 1991-04-17 2001-10-08 Merck & Co., Inc. Oftalmický prípravok na liečenie očnej hypertenzie obsahujúci kombináciu inhibítora karboanhydrázy a beta-adrenergného antagonistu
SG84487A1 (en) 1991-04-17 2001-11-20 Merck & Co Inc Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a b-adrenergic antagonist
US5352708A (en) 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5688819A (en) 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
JPH06107547A (ja) 1992-10-01 1994-04-19 Aarutetsuku Ueno:Kk 眼科用組成物
US5268624A (en) 1992-10-14 1993-12-07 Allergan, Inc. Foot pedal control with user-selectable operational ranges
US6184250B1 (en) 1993-08-03 2001-02-06 Alcon Laboratories, Inc. Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
AU692220B2 (en) 1993-12-20 1998-06-04 Biopolymerix, Inc. Non-leachable antimicrobial material and articles comprising same
US6051576A (en) 1994-01-28 2000-04-18 University Of Kentucky Research Foundation Means to achieve sustained release of synergistic drugs by conjugation
CA2237898A1 (en) 1995-11-17 1997-05-29 Louis Desantis Jr. Combination therapy for treating glaucoma
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CA2337399A1 (en) 1998-07-21 2000-02-03 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
EP1169061A1 (en) 1999-03-12 2002-01-09 Alcon Laboratories, Inc. Combination therapy for treating glaucoma
CN1525861A (zh) * 2001-05-14 2004-09-01 ��������˹�����տ����� 用于治疗眼压过高和青光眼的方法
TWI298257B (en) 2001-05-31 2008-07-01 Allergan Inc Hypotensive lipid and timolol compositions and methods of using same
US7074827B2 (en) 2002-10-24 2006-07-11 Sucampo Ag (Usa) Inc. Method for treating ocular hypertension and glaucoma
US8648213B2 (en) * 2004-10-06 2014-02-11 Allergan, Inc. Prostamides for the treatment of glaucoma and related diseases
ES2232319B1 (es) 2004-10-15 2006-08-16 Fico Mirrors, S.A. Metodo de control de un espejo electrocromico y sistema electrocromico, aplicables a un vehiculo automovil.
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
PL1937212T3 (pl) * 2005-10-10 2011-02-28 Santen Sas Emulsje oftalmiczne zawierające prostaglandyny
FR2918891B1 (fr) 2007-07-20 2009-09-25 Thea Sa Lab Solution ophtalmique a base de prostaglandines sans conservateur
US7469624B1 (en) 2007-11-12 2008-12-30 Jason Adams Direct drive retrofit for rifles
EP2127638A1 (en) * 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
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US9061034B2 (en) * 2010-07-29 2015-06-23 Allergan, Inc. Preservative free bimatoprost and timolol solutions
SI3431074T1 (sl) 2010-07-29 2022-07-29 Allergan, Inc. Raztopine bimatoprosta in timolola brez konzervansov

Also Published As

Publication number Publication date
US9078854B2 (en) 2015-07-14
HUE040488T2 (hu) 2019-03-28
AU2011282681B2 (en) 2015-07-30
WO2012015998A3 (en) 2012-04-12
CA2807081C (en) 2018-09-18
DK2598118T3 (en) 2018-12-10
WO2012015998A2 (en) 2012-02-02
US20160113934A1 (en) 2016-04-28
PL2598118T3 (pl) 2019-01-31
EP3431074B1 (en) 2022-01-19
PT3431074T (pt) 2022-05-23
US20140148455A1 (en) 2014-05-29
SI2598118T1 (sl) 2018-12-31
HUE059325T2 (hu) 2022-11-28
JP6014033B2 (ja) 2016-10-25
ES2708451T3 (es) 2019-04-09
RU2013107744A (ru) 2014-09-10
KR101820184B1 (ko) 2018-01-18
PT2598118T (pt) 2018-11-29
JP2013535472A (ja) 2013-09-12
EP3431074A1 (en) 2019-01-23
HRP20220626T1 (hr) 2022-06-24
EP2598118A2 (en) 2013-06-05
AU2011282681A1 (en) 2013-02-28
EP2598118B1 (en) 2018-09-05
KR20130052619A (ko) 2013-05-22
CN103068364A (zh) 2013-04-24
RU2624534C2 (ru) 2017-07-04
CA2807081A1 (en) 2012-02-02
ES2911174T3 (es) 2022-05-18
CN103068364B (zh) 2016-08-17

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